Xiaofeng Jia

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Residual motor signal in long-term human severed peripheral nerves and feasibility of neural signal-controlled artificial limb
    Xiaofeng Jia
    Department of Orthopedic Surgery, Zhong Shan Hospital, Fudan University, Shanghai, PR China
    J Hand Surg Am 32:657-66. 2007
  2. pmc Epidermal stem cells in orthopaedic regenerative medicine
    Jin Li
    Biomedical Engineering, The Johns Hopkins University School of Medicine, 720 Rutland Ave, Traylor 710B, Baltimore, MD 21205, USA
    Int J Mol Sci 14:11626-42. 2013
  3. doi request reprint Critical care of traumatic spinal cord injury
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Intensive Care Med 28:12-23. 2013
  4. pmc Post-cardiac arrest temperature manipulation alters early EEG bursting in rats
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Resuscitation 78:367-73. 2008
  5. pmc Early electrophysiologic markers predict functional outcome associated with temperature manipulation after cardiac arrest in rats
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 36:1909-16. 2008
  6. doi request reprint Improved long-term recording of nerve signal by modified intrafascicular electrodes in rabbits
    Xiaofeng Jia
    Department of Orthopedic Surgery, Zhong Shan Hospital, Fudan University, Shanghai, People s Republic of China
    Microsurgery 28:173-8. 2008
  7. pmc Improving neurological outcomes post-cardiac arrest in a rat model: immediate hypothermia and quantitative EEG monitoring
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Resuscitation 76:431-42. 2008
  8. pmc Quantitative EEG and neurological recovery with therapeutic hypothermia after asphyxial cardiac arrest in rats
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Brain Res 1111:166-75. 2006
  9. pmc Evolution of Somatosensory Evoked Potentials after Cardiac Arrest induced hypoxic-ischemic injury
    Wei Xiong
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Resuscitation 81:893-7. 2010
  10. pmc Quantitative assessment of somatosensory-evoked potentials after cardiac arrest in rats: prognostication of functional outcomes
    Jai Madhok
    Department of Biomedical Engineering, John Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 38:1709-17. 2010

Detail Information

Publications39

  1. ncbi request reprint Residual motor signal in long-term human severed peripheral nerves and feasibility of neural signal-controlled artificial limb
    Xiaofeng Jia
    Department of Orthopedic Surgery, Zhong Shan Hospital, Fudan University, Shanghai, PR China
    J Hand Surg Am 32:657-66. 2007
    ..We sampled potentials from peripheral nerve stumps with intrafascicular electrodes to study residual motor transmission and explore the feasibility of nerve signal-controlled artificial limbs...
  2. pmc Epidermal stem cells in orthopaedic regenerative medicine
    Jin Li
    Biomedical Engineering, The Johns Hopkins University School of Medicine, 720 Rutland Ave, Traylor 710B, Baltimore, MD 21205, USA
    Int J Mol Sci 14:11626-42. 2013
    ....
  3. doi request reprint Critical care of traumatic spinal cord injury
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Intensive Care Med 28:12-23. 2013
    ....
  4. pmc Post-cardiac arrest temperature manipulation alters early EEG bursting in rats
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Resuscitation 78:367-73. 2008
    ..EEG recovers through periodic bursting from isoelectricity after CA, the duration of which is associated with outcome in normothermia. We quantified burst frequency to study the effect of temperature on early EEG recovery after CA...
  5. pmc Early electrophysiologic markers predict functional outcome associated with temperature manipulation after cardiac arrest in rats
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 36:1909-16. 2008
    ..We studied the recovery of cortical electrical function by quantitative electroencephalography after 7-min asphyxial cardiac arrest, using information quantity (IQ)...
  6. doi request reprint Improved long-term recording of nerve signal by modified intrafascicular electrodes in rabbits
    Xiaofeng Jia
    Department of Orthopedic Surgery, Zhong Shan Hospital, Fudan University, Shanghai, People s Republic of China
    Microsurgery 28:173-8. 2008
    ..05) and a greater total functioning electrode time (P = 0.006). Intrafascicular electrodes with a spring-like structure demonstrated superior potential for long-term electrophysiological monitoring over straight electrodes...
  7. pmc Improving neurological outcomes post-cardiac arrest in a rat model: immediate hypothermia and quantitative EEG monitoring
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Resuscitation 76:431-42. 2008
    ..To enhance the administration of TH, we studied brain electrophysiological monitoring in determining the benefit of early initiation of TH compared to conventional administration in a rat model...
  8. pmc Quantitative EEG and neurological recovery with therapeutic hypothermia after asphyxial cardiac arrest in rats
    Xiaofeng Jia
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Brain Res 1111:166-75. 2006
    ..These results demonstrate the potential utility of qEEG-IQ to track the response to neuroprotective hypothermia during the early phase of recovery from cardiac arrest...
  9. pmc Evolution of Somatosensory Evoked Potentials after Cardiac Arrest induced hypoxic-ischemic injury
    Wei Xiong
    Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Resuscitation 81:893-7. 2010
    ..We tested the hypothesis that early recovery of cortical SEP would be associated with milder hypoxic-ischemic injury and better outcome after resuscitation from CA...
  10. pmc Quantitative assessment of somatosensory-evoked potentials after cardiac arrest in rats: prognostication of functional outcomes
    Jai Madhok
    Department of Biomedical Engineering, John Hopkins University School of Medicine, Baltimore, MD, USA
    Crit Care Med 38:1709-17. 2010
    ..Due to the vulnerability of these circuits to hypoxic-ischemic insults, we hypothesize that quantitative SSEP markers may indicate future neurologic status...
  11. doi request reprint Intraventricular orexin-A improves arousal and early EEG entropy in rats after cardiac arrest
    Matthew A Koenig
    The Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 8 140, Baltimore, MD 21287, USA
    Brain Res 1255:153-61. 2009
    ..14). In rats resuscitated from CA, orexin-A transiently increased arousal and EEG entropy without worsening ischemic neuronal injury. The role of orexin-A in recovery of arousal after CA deserves further investigation...
  12. ncbi request reprint Quantitative EEG assessment of brain injury and hypothermic neuroprotection after cardiac arrest
    Hyun Chool Shin
    Dept of Biomed Eng, Johns Hopkins Univ Sch of Med, Baltimore, MD 21205, USA
    Conf Proc IEEE Eng Med Biol Soc 1:6229-32. 2006
    ..Experimental results show that the IQ is higher for hypothermic than normothermic rats. The results quantitatively support the hypothesis that hypothermia accelerates the recovery of brain injury after cardiac arrest...
  13. doi request reprint Multiresolution entropy measure for neuronal multiunit activity
    Young Seok Choi
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205 USA
    Conf Proc IEEE Eng Med Biol Soc 2009:4715-8. 2009
    ..Simulation and Experimental results demonstrate that the dynamics of a population can be quantified by using the proposed multiresolution entropy...
  14. pmc Short- and long-latency somatosensory neuronal responses reveal selective brain injury and effect of hypothermia in global hypoxic ischemia
    Dan Wu
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurophysiol 107:1164-71. 2012
    ..In summary, our study reveals the vulnerability of the somatosensory neural structures to global HI and the differential effects of hypothermia on these structures...
  15. pmc A subband-based information measure of EEG during brain injury and recovery after cardiac arrest
    Hyun Chool Shin
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    IEEE Trans Biomed Eng 55:1985-90. 2008
    ..Thirteen rats, based on 7-min cardiac arrest were used. The experimental results show that the proposed measure was more highly correlated to neurological outcome than IQ...
  16. pmc Study of the origin of short- and long-latency SSEP during recovery from brain ischemia in a rat model
    Dan Wu
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neurosci Lett 485:157-61. 2010
    ....
  17. doi request reprint Scaling exponents of EEG are related to the temporal process of the therapeutic hypothermia following ischemic brain injury
    Dineng Jiang
    Department of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, PR China
    Conf Proc IEEE Eng Med Biol Soc 2009:2192-5. 2009
    ..gamma(2)(alpha)) were correlated with the delayed neuronal death after CA. Our preliminary results showed that the long-range correlations in theta and alpha bands could be related the detail temporal process of therapeutic hypothermia...
  18. doi request reprint Neural signals in cortex and thalamus during brain injury from cardiac arrest in rats
    Dandan Zhang
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:5946-9. 2009
    ..These results will help elucidate the mechanism of brain recovery after CA injury...
  19. pmc Multiscale entropy analysis of EEG for assessment of post-cardiac arrest neurological recovery under hypothermia in rats
    Xiaoxu Kang
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
    IEEE Trans Biomed Eng 56:1023-31. 2009
    ..These experiments point to the role of cortical rhythms in reporting early neurological response to ischemia and therapeutic hypothermia...
  20. pmc Quantitative EEG and effect of hypothermia on brain recovery after cardiac arrest
    Hyun Chool Shin
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    IEEE Trans Biomed Eng 53:1016-23. 2006
    ..20 (0.20 +/- 0.11 is 95% condidence interval). The results quantitatively support the hypothesis that hypothermia accelerates the electrical recovery from brain injury after cardiac arrest...
  21. pmc Application of Tsallis entropy to EEG: quantifying the presence of burst suppression after asphyxial cardiac arrest in rats
    - Dandan Zhang
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    IEEE Trans Biomed Eng 57:867-74. 2010
    ..86, p << 0.01 ). This research shows that TsEnA reliably quantifies the complex dynamics in BS EEG, and may be useful as an experimental or clinical tool for objective estimation of the gravity of brain damage after CA...
  22. pmc Time jitter of somatosensory evoked potentials in recovery from hypoxic-ischemic brain injury
    Ying Ma
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Neurosci Methods 201:355-60. 2011
    ..The SOBI technique is an efficient method in the identification of peak detection and offers a favorable alternative to reveal the neural transmission variation...
  23. pmc Management of brain injury after resuscitation from cardiac arrest
    Romergryko G Geocadin
    Neurosciences Critical Care Division, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Neurol Clin 26:487-506, ix. 2008
    ....
  24. doi request reprint Long-term assessment of post-cardiac-arrest neurological outcomes with somatosensory evoked potential in rats
    Xiaoxu Kang
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:2196-9. 2009
    ....
  25. doi request reprint Effect of hypothermia on the thalamocortical function in the rat model
    Anil Maybhate
    Department of Biomedical Engineering, Johns Hopkins University, 720 Rutland Avenue, Traylor Building, Room 710 C, Baltimore, MD 21205, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:4680-3. 2012
    ..These results could have important implications towards understanding of hypothermia...
  26. doi request reprint Diagnostic errors in orthopedic surgery: evaluation of resident documentation of neurovascular examinations for orthopedic trauma patients
    Eric W Tan
    Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA
    Am J Med Qual 28:60-8. 2013
    ..The element most often documented completely was the sensory examination. Increased examiner experience was significantly associated with decreased sensory and vascular documentation...
  27. pmc Hypothermia amplifies somatosensory-evoked potentials in uninjured rats
    Jai Madhok
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Neurosurg Anesthesiol 24:197-202. 2012
    ..Hypothermia also suppressed EEGs at different regions of the brain by different degrees. The changes to SSEP and EEG are both reversible with subsequent rewarming...
  28. doi request reprint Laser speckle imaging reveals multiple aspects of cerebral vascular responses to whole body mild hypothermia in rats
    Nan Li
    Biomedical Engineering Department, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:2049-52. 2011
    ..The results reported provide a circulatory explanation for the hypothermia therapeutic effects and mechanism...
  29. pmc Intraarticular abnormalities in overhead athletes are variable
    Ashvin K Dewan
    Division of Shoulder Surgery and the Department of Orthopaedic Surgery, Johns Hopkins Bayview Medical Center, The Johns Hopkins University, Baltimore, MD 21224 2780, USA
    Clin Orthop Relat Res 470:1552-7. 2012
    ..Several studies illustrate the wide variety of lesions seen at the time of arthroscopy in overhead athletes who require surgery but it is unclear whether these differ by sport...
  30. pmc Does a positive neer impingement sign reflect rotator cuff contact with the acromion?
    Xiaofeng Jia
    Division of Shoulder Surgery, Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA
    Clin Orthop Relat Res 469:813-8. 2011
    ..It has been assumed that the pain with a Neer impingement sign on physical examination of the shoulder was secondary to the rotator cuff making contact with the anterior and lateral acromion...
  31. doi request reprint Clinical and imaging assessment for superior labrum anterior and posterior lesions
    Edward G McFarland
    Division of Shoulder Surgery, Department of Orthopaedic Surgery, Johns Hopkins University, Baltimore, MD, USA
    Curr Sports Med Rep 8:234-9. 2009
    ....
  32. doi request reprint Statistical model applied to motor evoked potentials analysis
    Ying Ma
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
    Conf Proc IEEE Eng Med Biol Soc 2011:2001-4. 2011
    ..This statistical method eliminates the effects of anesthesia, and provides an objective assessment of MEPs. Consequently this statistical method has high potential to be useful in future quantitative MEPs analysis...
  33. doi request reprint Exploring high-frequency oscillation as a marker of brain ischemia using S-transform
    Dan Wu
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Conf Proc IEEE Eng Med Biol Soc 2010:6099-102. 2010
    ..05) and recovery dynamics (p=0.03) between the good- and bad-outcome groups. We consider the HFO to be reflective of the health of thalamocotical circuitry in brain ischemia...
  34. doi request reprint High spatiotemporal resolution imaging of the neurovascular response to electrical stimulation of rat peripheral trigeminal nerve as revealed by in vivo temporal laser speckle contrast
    Nan Li
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Neurosci Methods 176:230-6. 2009
    ..Dural vessels enlarged by 40+/-8% and the blood velocity increased by 50+/-5%. The method described here could be very useful in understanding and studying disorders in the neurovascular system...
  35. doi request reprint Reproducibility and reliability of the Snyder classification of superior labral anterior posterior lesions among shoulder surgeons
    Xiaofeng Jia
    Departments of Biomedical Engineering, Physical Medicine and Rehabilitation, The Johns Hopkins University, Baltimore, Maryland, USA
    Am J Sports Med 39:986-91. 2011
    ..Previous studies of the reliability of classifications for superior labral anterior and posterior (SLAP) lesions suggest that intraobserver/interobserver reliability is poor...
  36. pmc Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
    Gehua Zhen
    Department of Orthopaedic Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Nat Med 19:704-12. 2013
    ..Thus, high concentrations of active TGF-β1 in subchondral bone seem to initiate the pathological changes of osteoarthritis, and inhibition of this process could be a potential therapeutic approach to treating this disease...
  37. pmc Injury-activated transforming growth factor β controls mobilization of mesenchymal stem cells for tissue remodeling
    Mei Wan
    Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Stem Cells 30:2498-511. 2012
    ..Thus, TGFβ is an injury-activated messenger essential for the mobilization and recruitment of MSCs to participate in tissue repair/remodeling...
  38. doi request reprint Clinical and diagnostic tests for shoulder disorders: a critical review
    Edward G McFarland
    Division of Shoulder Surgery, Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, Maryland, USA
    Br J Sports Med 44:328-32. 2010
    ..The goals of this study were to review the current limitations of evidence-based medicine with regard to shoulder examination and to assess the rationale for and against the use of diagnostic physical examination tests...
  39. doi request reprint An analysis of shoulder laxity in patients undergoing shoulder surgery
    Xiaofeng Jia
    Department of Orthopaedic Surgery, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224 2780, USA
    J Bone Joint Surg Am 91:2144-50. 2009
    ..We hypothesized that, on examination with the patient under anesthesia, most shoulders could be subluxated over the glenoid rim and that the degree of shoulder laxity would be related to diagnosis...