Yoon Young Jang

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Molecular imaging and stem cell research
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center, JohnsHopkins University School of Medicine, Baltimore, MD 21231, USA
    Mol Imaging 10:111-22. 2011
  2. ncbi request reprint Fetal to adult stem cell transition: knocking Sox17 off
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Cell 130:403-4. 2007
  3. pmc A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Blood 110:3056-63. 2007
  4. ncbi request reprint Hematopoietic stem cells convert into liver cells within days without fusion
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Nat Cell Biol 6:532-9. 2004
  5. pmc Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells
    Su Mi Choi
    Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Hepatology 57:2458-68. 2013
  6. pmc Liver engraftment potential of hepatic cells derived from patient-specific induced pluripotent stem cells
    Su Mi Choi
    Stem Cell Biology Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cell Cycle 10:2423-7. 2011
  7. pmc Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent stem cells
    Su Mi Choi
    Stem Cell Biology Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Blood 118:1801-5. 2011
  8. ncbi request reprint Metamorphosis from bone marrow derived primitive stem cells to functional liver cells
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Cell Cycle 3:980-2. 2004
  9. ncbi request reprint Stem cell plasticity: a rare cell, not a rare event
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Stem Cell Rev 1:45-51. 2005
  10. pmc Hematopoietic cells as sources for patient-specific iPSCs and disease modeling
    Zhaohui Ye
    Division of Hematology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cell Cycle 10:2840-4. 2011

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Molecular imaging and stem cell research
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center, JohnsHopkins University School of Medicine, Baltimore, MD 21231, USA
    Mol Imaging 10:111-22. 2011
    ..In this review, we discuss the application of current imaging modalities for research of hematopoietic stem cells and pluripotent stem cells and the challenges ahead...
  2. ncbi request reprint Fetal to adult stem cell transition: knocking Sox17 off
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Cell 130:403-4. 2007
    ..2007) demonstrate in mice that the endodermal transcription factor Sox17 is required for the maintenance of fetal and neonatal but not adult HSCs...
  3. pmc A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Blood 110:3056-63. 2007
    ..The ROS-related signaling pathways together with specific characteristics of niche HSCs may serve as targets for beneficial therapies...
  4. ncbi request reprint Hematopoietic stem cells convert into liver cells within days without fusion
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Nat Cell Biol 6:532-9. 2004
    ..Notably, liver function was restored 2-7 d after transplantation. We conclude that HSCs contribute to the regeneration of injured liver by converting into functional hepatocytes without fusion...
  5. pmc Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells
    Su Mi Choi
    Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Hepatology 57:2458-68. 2013
    ....
  6. pmc Liver engraftment potential of hepatic cells derived from patient-specific induced pluripotent stem cells
    Su Mi Choi
    Stem Cell Biology Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cell Cycle 10:2423-7. 2011
    ....
  7. pmc Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent stem cells
    Su Mi Choi
    Stem Cell Biology Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Blood 118:1801-5. 2011
    ..The ability to reprogram the widely banked patient B-cell lines will offer an unprecedented opportunity to generate human disease models and provide novel drug therapies...
  8. ncbi request reprint Metamorphosis from bone marrow derived primitive stem cells to functional liver cells
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA
    Cell Cycle 3:980-2. 2004
    ..Functional repair should also be demonstrated prior to treatment in patients...
  9. ncbi request reprint Stem cell plasticity: a rare cell, not a rare event
    Yoon Young Jang
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Stem Cell Rev 1:45-51. 2005
    ..It is important to dissect the relationship between primitive/tissue-specific SCs and regenerative signals...
  10. pmc Hematopoietic cells as sources for patient-specific iPSCs and disease modeling
    Zhaohui Ye
    Division of Hematology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cell Cycle 10:2840-4. 2011
    ..Here we describe the recent advances in generating disease specific human iPSCs from these different types of hematopoietic cells and their potential applications in disease modeling and regenerative medicine...
  11. pmc In vivo liver regeneration potential of human induced pluripotent stem cells from diverse origins
    Hua Liu
    Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Sci Transl Med 3:82ra39. 2011
    ....
  12. pmc Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders
    Zhaohui Ye
    Stem Cell Program, Institute for Cell Engineering, and Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Blood 114:5473-80. 2009
    ..These iPS cells provide a renewable cell source and a prospective hematopoiesis model for investigating MPD pathogenesis...
  13. pmc Pluripotent stem cell-based cancer therapy: promise and challenges
    Saul J Sharkis
    Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Sci Transl Med 4:127ps9. 2012
    ..Here, we discuss the potential therapeutic applications of iPSCs for treating cancer and other diseases and highlight the current barriers restricting their use...
  14. pmc Generation of endoderm-derived human induced pluripotent stem cells from primary hepatocytes
    Hua Liu
    Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Hepatology 51:1810-9. 2010
    ..In addition, these cells are able to directly differentiate into definitive endoderm, hepatic progenitors, and mature hepatocytes...
  15. pmc Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells
    Hsing Chen Tsai
    The Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Cancer Cell 21:430-46. 2012
    ..Low-dose decitabine and azacitidine may have broad applicability for cancer management...