Suzanne Jan de Beur

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Molecular pathogenesis of hypophosphatemic rickets
    Suzanne M Jan De Beur
    Division of Endocrinology and Metabolism, Department of Medicine, Ilyssa Center for Molecular and Cellular Endocrinology, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Baltimore, MD 21287, USA
    J Clin Endocrinol Metab 87:2467-73. 2002
  2. ncbi request reprint The pseudohypoparathyroidism type lb locus is linked to a region including GNAS1 at 20q13.3
    Suzanne M Jan De Beur
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    J Bone Miner Res 18:424-33. 2003
  3. pmc Discordance between genetic and epigenetic defects in pseudohypoparathyroidism type 1b revealed by inconsistent loss of maternal imprinting at GNAS1
    Suzanne Jan de Beur
    Division of Endocrinology and Metabolism, Department of Medicine, and the Ilyssa Center for Molecular and Cellular Endocrinology, The Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA
    Am J Hum Genet 73:314-22. 2003
  4. ncbi request reprint Tumor-induced osteomalacia
    Suzanne M Jan De Beur
    Department of Medicine, Johns Hopkins University School of Medicine, and Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA
    JAMA 294:1260-7. 2005
  5. ncbi request reprint Exercise effects on bone mineral density relationships to changes in fitness and fatness
    Kerry J Stewart
    Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland 21224, USA
    Am J Prev Med 28:453-60. 2005
  6. pmc Serum 25-hydroxyvitamin D, calcium, phosphorus, and electrocardiographic QT interval duration: findings from NHANES III and ARIC
    Yiyi Zhang
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 2024 East Monument Street, Baltimore, Maryland 21205, USA
    J Clin Endocrinol Metab 96:1873-82. 2011
  7. ncbi request reprint Growth hormone deficiency in pseudohypoparathyroidism type 1a: another manifestation of multihormone resistance
    Emily L Germain-Lee
    Department of Pediatrics, Division of Endocrinology and the Ilyssa Center for Molecular Endocrinology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Clin Endocrinol Metab 88:4059-69. 2003
  8. pmc Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent
    Theresa Berndt
    Department of Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Clin Invest 112:785-94. 2003
  9. ncbi request reprint Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literature
    Andrew L Folpe
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
    Am J Surg Pathol 28:1-30. 2004
  10. ncbi request reprint Consumptive hypothyroidism caused by paraneoplastic production of type 3 iodothyronine deiodinase
    Mary D Ruppe
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Thyroid 15:1369-72. 2005

Research Grants

  1. PHOSPHOTONIN--A NOVEL PHOSPHATE REGULATORY HORMONE
    Suzanne Jan de Beur; Fiscal Year: 2003
  2. Role of FGF-23 in Regulation of Phosphate Homeostasis
    Suzanne Jan de Beur; Fiscal Year: 2004
  3. MOLECULAR PATHOGENESIS OF HYPOPHOSPHATEMIC RICKETS
    Suzanne Jan de Beur; Fiscal Year: 2009
  4. MOLECULAR PATHOGENESIS OF HYPOPHOSPHATEMIC RICKETS
    Suzanne M Jan De Beur; Fiscal Year: 2010

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Molecular pathogenesis of hypophosphatemic rickets
    Suzanne M Jan De Beur
    Division of Endocrinology and Metabolism, Department of Medicine, Ilyssa Center for Molecular and Cellular Endocrinology, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Baltimore, MD 21287, USA
    J Clin Endocrinol Metab 87:2467-73. 2002
  2. ncbi request reprint The pseudohypoparathyroidism type lb locus is linked to a region including GNAS1 at 20q13.3
    Suzanne M Jan De Beur
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    J Bone Miner Res 18:424-33. 2003
    ..Our data confirm that PHP1b is linked to a region that includes GNAS1, and further refine the locus, although the primary genetic mutation(s) that causes defective imprinting of GNAS1 remains undefined...
  3. pmc Discordance between genetic and epigenetic defects in pseudohypoparathyroidism type 1b revealed by inconsistent loss of maternal imprinting at GNAS1
    Suzanne Jan de Beur
    Division of Endocrinology and Metabolism, Department of Medicine, and the Ilyssa Center for Molecular and Cellular Endocrinology, The Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA
    Am J Hum Genet 73:314-22. 2003
    ....
  4. ncbi request reprint Tumor-induced osteomalacia
    Suzanne M Jan De Beur
    Department of Medicine, Johns Hopkins University School of Medicine, and Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA
    JAMA 294:1260-7. 2005
    ..In this article, the distinctive clinical characteristics of this syndrome, the advances in diagnosis of TIO, and new insights into the pathophysiology of this disorder are discussed...
  5. ncbi request reprint Exercise effects on bone mineral density relationships to changes in fitness and fatness
    Kerry J Stewart
    Division of Cardiology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland 21224, USA
    Am J Prev Med 28:453-60. 2005
    ..Weight loss typically reduces bone mineral density (BMD). Exercise may preserve or increase BMD even while reducing fatness. We examined the relationships among exercise-induced changes in fitness and fatness with BMD...
  6. pmc Serum 25-hydroxyvitamin D, calcium, phosphorus, and electrocardiographic QT interval duration: findings from NHANES III and ARIC
    Yiyi Zhang
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 2024 East Monument Street, Baltimore, Maryland 21205, USA
    J Clin Endocrinol Metab 96:1873-82. 2011
    ....
  7. ncbi request reprint Growth hormone deficiency in pseudohypoparathyroidism type 1a: another manifestation of multihormone resistance
    Emily L Germain-Lee
    Department of Pediatrics, Division of Endocrinology and the Ilyssa Center for Molecular Endocrinology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Clin Endocrinol Metab 88:4059-69. 2003
    ..Our data indicate that GH deficiency is common (69%) in PHP type 1a and may contribute to the obesity and short stature typical of AHO. We propose that GH status be evaluated in all patients with PHP type 1a...
  8. pmc Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent
    Theresa Berndt
    Department of Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Clin Invest 112:785-94. 2003
    ..Thus, sFRP-4 displays phosphatonin-like properties, because it is a circulating protein that promotes phosphaturia and hypophosphatemia and blunts compensatory increases in 1alpha, 25-dihydroxyvitamin D...
  9. ncbi request reprint Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literature
    Andrew L Folpe
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
    Am J Surg Pathol 28:1-30. 2004
    ..Recognition of PMTMCT is critical, as complete resection cures intractable OO. Immunohistochemistry and RT-PCR for FGF-23 confirm the role of this protein in PMTMCT-associated OO...
  10. ncbi request reprint Consumptive hypothyroidism caused by paraneoplastic production of type 3 iodothyronine deiodinase
    Mary D Ruppe
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Thyroid 15:1369-72. 2005
    ....
  11. ncbi request reprint Localisation of mesenchymal tumours by somatostatin receptor imaging
    Suzanne M Jan De Beur
    Lancet 359:761-3. 2002
    ..Our findings suggest that 111In-pentetreotide imaging effectively detects occult mesenchymal tumours and facilitates surgical treatment of oncogenic osteomalacia...

Research Grants7

  1. PHOSPHOTONIN--A NOVEL PHOSPHATE REGULATORY HORMONE
    Suzanne Jan de Beur; Fiscal Year: 2003
    ..abstract_text> ..
  2. Role of FGF-23 in Regulation of Phosphate Homeostasis
    Suzanne Jan de Beur; Fiscal Year: 2004
    ..Elucidating the molecular mechanism by which FGF-23 causes renal phosphate wasting will contribute substantially to our understanding of the role of FGF-23 in phosphate homeostasis. ..
  3. MOLECULAR PATHOGENESIS OF HYPOPHOSPHATEMIC RICKETS
    Suzanne Jan de Beur; Fiscal Year: 2009
    ..A better understanding of FGF-23 signaling and its consequences for renal phosphate handling and ultimately skeletal mineralization will provide new therapeutic targets for disorders of phosphate homeostasis. ..
  4. MOLECULAR PATHOGENESIS OF HYPOPHOSPHATEMIC RICKETS
    Suzanne M Jan De Beur; Fiscal Year: 2010
    ..A better understanding of FGF-23 signaling and its consequences for renal phosphate handling and ultimately skeletal mineralization will provide new therapeutic targets for disorders of phosphate homeostasis. ..