Research Topics
| L P JacobsonSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
CD4 count at presentation for HIV care in the United States and Canada: are those over 50 years more likely to have a delayed presentation?Keri N Althoff
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD, 21205, USA
AIDS Res Ther 7:45. 2010..10%, respectively). Due to the increasing proportion, consistently lower CD4 counts, and more advanced HIV disease in adults ≥50-year-old at first presentation for HIV care, renewed HIV testing efforts are needed...
Virologic and immunologic response to highly active antiretroviral therapyLisa P Jacobson
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Curr HIV/AIDS Rep 1:74-81. 2004....- Evaluation of the effectiveness of highly active antiretroviral therapy in persons with human immunodeficiency virus using biomarker-based equivalence of disease progressionL P Jacobson
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 155:760-70. 2002.... - Impact of potent antiretroviral therapy on the incidence of Kaposi's sarcoma and non-Hodgkin's lymphomas among HIV-1-infected individuals. Multicenter AIDS Cohort StudyL P Jacobson
Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland 21205, USA
J Acquir Immune Defic Syndr 21:S34-41. 1999..With additional follow-up, an impact on NHL may yet be observed... - Interaction of human immunodeficiency virus type 1 and human herpesvirus type 8 infections on the incidence of Kaposi's sarcomaL P Jacobson
Department of Epidemiology, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21205, USA
J Infect Dis 181:1940-9. 2000..The quicker development of KS in men acquiring HHV-8 after HIV-1 and its association with CD4 slope argues that KS is more likely if HHV-8 infection occurs in an immunocompromised person... - Therapy naivete in the era of potent antiretroviral therapyL P Jacobson
Department of Epidemiology, The Johns Hopkins School of Hygiene and Public Health, Baltimore, MD 21205, USA
J Clin Epidemiol 54:149-56. 2001..In this era of effective ART, use was not universal. Besides disease markers, these nonclinical determinants need to be considered for promoting population therapy effectiveness... - Immunologic and virologic response to highly active antiretroviral therapy in the Multicenter AIDS Cohort StudyT E Yamashita
Johns Hopkins School of Public Health, Baltimore, Maryland 21205, USA
AIDS 15:735-46. 2001..Age, level of immune competence and immunogenetics appeared to play a role in the subsequent immune reconstitution following use of highly effective HIV therapy... - Thrush and fever as markers of immune competence in the era of highly active antiretroviral therapyR L Skolasky
Department of Epidemiology, Johns Hopkins University School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA
AIDS Res Hum Retroviruses 17:1311-6. 2001..These results provide evidence that increases in CD4+ T cell count due to HAART represent a reconstitution of immune function... - Oltipraz chemoprevention trial in Qidong, People's Republic of China: modulation of serum aflatoxin albumin adduct biomarkersT W Kensler
Department of Environmental Health Sciences, Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland 21205, USA
Cancer Epidemiol Biomarkers Prev 7:127-34. 1998..A follow-up Phase IIb trial with a longer intervention period will be necessary to determine the full extent to which aflatoxin biomarker burden can be reduced and whether diminution of biomarkers can be sustained over the long term... - Determinants of heterogeneous adherence to HIV-antiretroviral therapies in the Multicenter AIDS Cohort StudyC A Kleeberger
Department of Epidemiology, The Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland 21205, USA
J Acquir Immune Defic Syndr 26:82-92. 2001..Identification of individuals with characteristics associated with lower adherence provides the basis for interventions to enhance adherence and optimize effective therapies... - Interruption and discontinuation of highly active antiretroviral therapy in the multicenter AIDS cohort studyXiuhong Li
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
J Acquir Immune Defic Syndr 38:320-8. 2005..CONCLUSIONS: Host characteristics play a role in short interruptions, whereas longer interruptions may be clinically indicated. These longer stoppages had further virologic and immunologic consequences, however... - Zidovudine use in AIDS-free HIV-1-seropositive homosexual men in the Multicenter AIDS Cohort Study (MACS), 1987-1989N M Graham
Department of Epidemiology, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland
J Acquir Immune Defic Syndr 4:267-76. 1991..No important differences were found in demographic or major clinical variables between clinical trial participants and zidovudine nonusers in this study... - Relationship between a frailty-related phenotype and progressive deterioration of the immune system in HIV-infected menLoic Desquilbet
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Acquir Immune Defic Syndr 50:299-306. 2009..Using a frailty-related phenotype (FRP), we investigated in the Multicenter AIDS Cohort Study whether progressive deterioration of the immune system among HIV-positive individuals independently predicts onset of FRP... - Emergence and persistence of CXCR4-tropic HIV-1 in a population of men from the multicenter AIDS cohort studyJames C Shepherd
School of Medicine, Johns Hopkins University, MD, USA
J Infect Dis 198:1104-12. 2008..We conclude that HIV-1 variants that used X4 frequently emerged at high CD4(+) T cell counts and may contribute to the decrease in T cell numbers during late HIV-1 infection... - A case-control study of HIV-1-related dementia and co-infection with HHV-8S Polk
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Neurology 59:950-3. 2002..The HHV-8 seropositivity of 210 male age- and HIV disease stage-matched cases and controls was compared. The overall HHV-8 seropositivity of 66% was similar among demented HIV-infected cases and nondemented HIV-infected controls... - Time scale and adjusted survival curves for marginal structural cox modelsDaniel Westreich
Department of Epidemiology, Universityof North Carolina, Chapel Hill, NorthCarolina, USA
Am J Epidemiol 171:691-700. 2010..In the present example, use of time on treatment yielded a hazard ratio further from the null and more precise than use of time on study as the time scale... - Sexual activity and Kaposi's sarcoma among human immunodeficiency virus type 1 and human herpesvirus type 8-coinfected menEric W Nawar
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Ann Epidemiol 18:517-21. 2008..Here, we explore sexual activity as a proxy for a sexually transmitted determinant beyond HIV-1 and HHV-8... - A comparison of ad hoc methods to account for non-cancer AIDS and deaths as competing risks when estimating the effect of HAART on incident cancer AIDS among HIV-infected menMeredith S Shiels
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
J Clin Epidemiol 63:459-67. 2010.... - Effect of tuberculosis on the survival of HIV-infected men in a country with low tuberculosis incidenceHugo Lopez-Gatell
Directorate of Epidemiology, Ministry of Health, Mexico, Mexico
AIDS 22:1869-73. 2008..2-4.7). Results underscore the importance of avoiding TB by using preventive interventions such as treatment of latent TB infection, particularly in populations with a large prevalence of HIV/TB co-infected individuals... - Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of ChinaThomas W Kensler
Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Room E7541, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 14:2605-13. 2005..29). Understanding factors influencing glucosinolate hydrolysis and bioavailability will be required for optimal use of broccoli sprouts in human interventions... - Cancer incidence in the multicenter AIDS Cohort Study before and during the HAART era: 1984 to 2007Eric C Seaberg
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
Cancer 116:5507-16. 2010.... - Impacts of HIV infection and HAART use on quality of lifeChenglong Liu
Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205, USA
Qual Life Res 15:941-9. 2006..Changes in QOL related to the use of highly active antiretroviral therapy (HAART) have been inconsistent and it is unknown how QOL after HAART compares to pre-infection levels... - HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailtyLoic Desquilbet
Department of Epidemiology, Bloomberg School of Public Health, John Hopkins University, Baltimore, Maryland 21205, USA
J Gerontol A Biol Sci Med Sci 62:1279-86. 2007..We investigated whether HIV infection increases the prevalence of a frailty-related phenotype (FRP) that approximates a clinical definition of frailty... - Patterns and predictors of changes in adherence to highly active antiretroviral therapy: longitudinal study of men and womenMariana Lazo
Johns Hopkins University Bloomberg School of Public Health, Epidemiology, Baltimore, MD 21205, USA
Clin Infect Dis 45:1377-85. 2007..Adherence to therapy is a dynamic behavior. However, few studies have identified factors associated with changes in adherence to highly active antiretroviral therapy (HAART) among men and women... - The relationship between antibody to R7V and progression of HIV type 1 infectionJoseph B Margolick
Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
AIDS Res Hum Retroviruses 26:389-94. 2010..The early presence of anti-R7VAb in HIV-1 seroconverters was not associated with slower progression of HIV-1 disease... - Failure to restore the Vgamma2-Jgamma1.2 repertoire in HIV-infected men receiving highly active antiretroviral therapy (HAART)Andrew M Hebbeler
Institute of Human Virology, University of Maryland School of Medicine, 725 West Lombard Street, Baltimore, Maryland 21201, USA
Clin Immunol 128:349-57. 2008..2Vdelta2 T cell repertoire did not recover after HAART initiation irrespective of treatment duration. These studies highlight important defects among cell subsets lost due to indirect effects of HIV... - Investigation of pre-diagnostic virological markers for progressive multifocal leukoencephalopathy in human immunodeficiency virus-infected patientsMary K Grabowski
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
J Med Virol 81:1140-50. 2009..0, 95% CI: 1.2-394.5). The results suggest that persistent JCV viruria and increasing urinary concentration of JCV DNA may be predictive of PML for some patients... 
Incidence and epidemiology of anal cancer in the multicenter AIDS cohort studyGypsyamber D'Souza
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Acquir Immune Defic Syndr 48:491-9. 2008..To examine the incidence and risk factors for anal cancer in a multicenter cohort of human immunodeficiency virus (HIV) positive and HIV-negative men who have sex with men followed between 1984 and 2006 (Multicenter AIDS Cohort Study)...- Effect of HAART on incident cancer and noncancer AIDS events among male HIV seroconvertersMeredith S Shiels
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, 615 North Wolfe Street, Room E7133, Baltimore, MD 21205, USA
J Acquir Immune Defic Syndr 48:485-90. 2008..To explore the impact of highly active antiretroviral therapy (HAART) on the prevention of AIDS-defining cancers relative to other AIDS-defining events... - Individual variation in CD4 cell count trajectory among human immunodeficiency virus-infected men and women on long-term highly active antiretroviral therapy: an application using a Bayesian random change-point modelHaitao Chu
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 162:787-97. 2005..At the individual level, 35% of men in the Multicenter AIDS Cohort Study versus 25% of women in the Women's Interagency HIV Study had a statistically significant change in CD4 cell count trajectory within 7 years after HAART initiation... - Changes in adherence to highly active antiretroviral therapy medications in the Multicenter AIDS Cohort StudyCynthia A Kleeberger
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
AIDS 18:683-8. 2004..CONCLUSION: Characteristics associated with improving and lowering adherence differed and should be considered in developing interventions to enhance adherence and optimize effective therapies... - Strategies for chemoprevention of liver cancerThomas W Kensler
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Eur J Cancer Prev 11:S58-64. 2002..Both chemopreventive agents modulated levels of aflatoxin biomarkers in the study participants in manners consonant with protection... - Chemoprevention of hepatocellular carcinoma in aflatoxin endemic areasThomas W Kensler
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, Maryland 21205, USA
Gastroenterology 127:S310-8. 2004.... - When to initiate highly active antiretroviral therapy: a cohort approachLinda Ahdieh-Grant
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Epidemiol 157:738-46. 2003..Furthermore, results suggest a potential threshold for HAART initiation in the neighborhood of 275 cells/microl... - Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, ChinaPatricia A Egner
Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Cancer Prev Res (Phila) 4:384-95. 2011..Cancer Prev Res; 4(3); 384-95. ©2011 AACR... - Age and racial/ethnic differences in the prevalence of reported symptoms in human immunodeficiency virus-infected persons on antiretroviral therapyMichael J Silverberg
Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA
J Pain Symptom Manage 38:197-207. 2009..Clinicians should consider these factors when counseling patients regarding potential adverse effects of antiretrovirals or symptoms associated with HIV disease... - Predictors for lower quality of life in the HAART era among HIV-infected menChenglong Liu
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
J Acquir Immune Defic Syndr 42:470-7. 2006..Modifiable determinants of lower QOL should be identified for interventions specifically targeted to the HAART-using individuals to improve their QOL... - Anthropometry in the prediction of sleep disordered breathing in HIV-positive and HIV-negative menTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD, USA
Antivir Ther 15:651-9. 2010.... - Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancerP A Egner
Department of Environmental Health Sciences and Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
Proc Natl Acad Sci U S A 98:14601-6. 2001.... - Factors associated with human herpesvirus type 8 infection in an injecting drug user cohortKyle T Bernstein
Department of Epidemiology, The Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland 21205, USA
Sex Transm Dis 30:199-204. 2003..5; = 0.085). CONCLUSION: The seroprevalence of HHV-8 in this population is similar to that seen in the general population, with risk factors being more consistent with sexual behaviors than injection drug use... - Plasma antibodies against Chlamydia trachomatis, human papillomavirus, and human herpesvirus type 8 in relation to prostate cancer: a prospective studySiobhan Sutcliffe
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6132 A, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 16:1573-80. 2007..70; 95% CI, 0.52-0.95). As this study is the first, to our knowledge, to observe such an inverse association, similar additional studies are warranted... - Late presentation for human immunodeficiency virus care in the United States and CanadaKeri N Althoff
Johns Hopkins University, Baltimore, Maryland, USA
Clin Infect Dis 50:1512-20. 2010..CONCLUSION. CD4 count at first presentation for HIV care has increased annually over the past 11 years but has remained <350 cells/mm(3), which suggests the urgent need for earlier HIV diagnosis and treatment... - Cohort profile: the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD)Stephen J Gange
NA-ACCORD Coordinating Center, Baltimore, MD 21287, USA
Int J Epidemiol 36:294-301. 2007 - The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphomaBrahim Aissani
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
J Acquir Immune Defic Syndr 52:170-9. 2009..Which gene variant on this highly conserved extended haplotype (CEH 8.1) in whites most likely represents a true etiologic factor remains uncertain... - The association of backpack use and back pain in adolescentsGeraldine I Sheir-Neiss
Department of Research, Alfred I. duPont Hospital for Children, Wilmington, Delaware 19899, USA
Spine 28:922-30. 2003..CONCLUSION: The use of backpacks during the school day and backpack weights are independently associated with back pain... - Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and menRobert C Kaplan
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
AIDS 22:1615-24. 2008..To assess the association of HIV infection, HIV disease parameters (including CD4+ T-cell counts, HIV viral load, and AIDS) and antiretroviral medication use with subclinical carotid artery atherosclerosis... - The complexity of HLA class II (DRB1, DQB1, DM) associations with disseminated Mycobacterium avium complex infection among HIV-1-seropositive whitesEknath Naik
Department of Epidemiology and Biostatistics, University of South Florida, Tampa, Florida, USA
J Acquir Immune Defic Syndr 33:140-5. 2003.... - Association of polymorphisms in human leukocyte antigen class I and transporter associated with antigen processing genes with resistance to human immunodeficiency virus type 1 infectionChenglong Liu
School of Public Health, University of California, Los Angeles, CA 90095, USA
J Infect Dis 187:1404-10. 2003..In multivariate logistic analysis, only the A*0205 subgroup (OR, 5.56; 95% CI, 1.34-23.10; P=.018) and the TAP2 Ala665 (OR, 2.22; 95% CI, 1.28-3.84; P=.005) were associated with resistance... - Effect of highly active antiretroviral therapy on survival among HIV-infected men with Kaposi sarcoma or non-Hodgkin lymphomaHenry K Tam
School of Public Health, University of California, Los Angeles, CA 90095-1772, USA
Int J Cancer 98:916-22. 2002..The use of HAART prolongs overall survival among HIV-positive men diagnosed with KS and NHL. HAART appears to be effective in improving survival even when initiated after the diagnosis of NHL and KS... - Attitudes towards highly active antiretroviral therapy are associated with sexual risk taking among HIV-infected and uninfected homosexual menDavid E Ostrow
Loyola University School of Medicine, Maywood, Illinois, USA
AIDS 16:775-80. 2002..Prevention programs should take into account underlying attitudes for unprotected sex in the era of HAART among both HIV-infected and uninfected men... - Changes in the incidence and predictors of wasting syndrome related to human immunodeficiency virus infection, 1987-1999Ellen Smit
Department of Social and Preventive Medicine, School of Medicine and Biological Sciences, University at Buffalo, Buffalo, NY 14214 3000, USA
Am J Epidemiol 156:211-8. 2002..05) and potent ART (p = 0.097). Predictors of wasting have changed with potent ART. Further research is needed to determine whether lipodystrophy may be misdiagnosed as wasting syndrome... - Non-Hodgkin's B cell lymphoma in persons with acquired immunodeficiency syndrome is associated with increased serum levels of IL10, or the IL10 promoter -592 C/C genotypeElizabeth Crabb Breen
Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
Clin Immunol 109:119-29. 2003..009), even when controlling for race (P = 0.006). These results suggest that elevated serum IL10 or the IL10 promoter -592 C/C genotype are associated with development of AIDS lymphoma... - Antiretroviral therapy is associated with an atherogenic lipoprotein phenotype among HIV-1-infected men in the Multicenter AIDS Cohort StudySharon A Riddler
Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Acquir Immune Defic Syndr 48:281-8. 2008..Alterations in serum lipids and an increased risk of myocardial infarction have been associated with HIV-1 infection and its treatment... - Dominant effects of CCR2-CCR5 haplotypes in HIV-1 disease progressionCheryl A Winkler
Laboratory of Genomic Diversity, Division of Basic Research, SAIC Frederick, NCI, Frederick, MD, USA
J Acquir Immune Defic Syndr 37:1534-8. 2004.... - Early and delayed benefits of HIV-1 suppression: timeline of recovery of innate immunity effector cellsLivio Azzoni
The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA
AIDS 21:293-305. 2007..The kinetics of recovery for innate immune effectors following antiretroviral therapy are unknown... - The relationship between methamphetamine and popper use and risk of HIV seroconversion in the multicenter AIDS cohort studyMichael W Plankey
Department of Medicine, Division of Infectious Diseases, Georgetown University Medical Center, Washington, DC 20007, USA
J Acquir Immune Defic Syndr 45:85-92. 2007..The association between methamphetamine use and HIV seroconversion for men who have sex with men (MSM) was examined using longitudinal data from the Multicenter AIDS Cohort Study... - Prospective study of attitudinal and relationship predictors of sexual risk in the multicenter AIDS cohort studyDavid G Ostrow
David Ostrow and Associates, Chicago MACS Howard Brown Health Center and Northwestern University School of Medicine, 5455 N Sheridan Rd, Suite 1207, Chicago, IL 60640, USA
AIDS Behav 12:127-38. 2008..We conclude that HIV prevention efforts should target modifiable attitudes (reduced concern about HIV and safer sex fatigue) and increases in sexual risk-taking of MSM, particularly among HIV+ men having sex with serodiscordant partners... - Macrolide use and the risk of vascular disease in HIV-infected men in the Multicenter AIDS Cohort StudyIan J Woolley
Infectious Diseases Department, Alfred Hospital, Monash University Medical School, Prahran 3004, Victoria, Australia
Sex Health 4:111-9. 2007..This study examined the risk of thromboembolic events in HIV-infected and non-infected individuals and the effect of macrolide prophylaxis on those outcomes... - Prognostic value of HIV-1 RNA, CD4 cell count, and CD4 Cell count slope for progression to AIDS and death in untreated HIV-1 infectionJohn W Mellors
JAMA 297:2349-50. 2007 - HLA-B, -DRB1/3/4/5, and -DQB1 gene polymorphisms in human immunodeficiency virus-related Kaposi's sarcomaM Tevfik Dorak
Department of Epidemiology and Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
J Med Virol 76:302-10. 2005..Alternatively, the relationship might hold a clue to the predilection of KS for men because that haplotype harbors the mutant form of the 21-hydroxylase gene... - Estimating the benefit of an HIV-1 vaccine that reduces viral load set pointSwati B Gupta
Merck Research Laboratories, West Point, PA, USA
J Infect Dis 195:546-50. 2007..5-1.25 log(10) copies/mL lower than the reference group. By quantifying the anticipated clinical benefits associated with a reduction in viral set point, these findings support the use of virologic end points in HIV-1 vaccine trials... - FcgammaRIIa genotype predicts progression of HIV infectionDonald N Forthal
Division of Infectious Diseases, Department of Medicine, University of California, Irvine School of Medicine, Irvine, CA 92697, USA
J Immunol 179:7916-23. 2007..These results demonstrate the importance of FcgammaRs in AIDS pathogenesis and point toward a critical role for interactions between FcgammaRs and immune complexes in disease progression... - Recreational drug use and T lymphocyte subpopulations in HIV-uninfected and HIV-infected menChun Chao
Department of Epidemiology and Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90095 1772, USA
Drug Alcohol Depend 94:165-71. 2008..These results indicate that use of these substances does not adversely affect the numbers and percentages of circulating CD4 or CD8 T cells in either HIV-uninfected or -infected MSM... - Lack of evidence for changing virulence of HIV-1 in North AmericaJoshua T Herbeck
University of Washington School of Medicine, Seattle, Washington, USA
PLoS ONE 3:e1525. 2008.... - Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survivalSher L Hendrickson
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
J Acquir Immune Defic Syndr 48:263-71. 2008..27; P=0.01). ARG influence after HAART suggests residual HIV-1 replication, and spread continues even in patients successfully suppressing detectable viral RNA... - HIV-1 variation before seroconversion in men who have sex with men: analysis of acute/early HIV infection in the multicenter AIDS cohort studyGeoffrey S Gottlieb
Division of Allergy and Infectious Diseases, Department of Medicine, School of Medicine, University of Washington, Seattle 98195, USA
J Infect Dis 197:1011-5. 2008..Nearly all variants were predicted to be CCR5 tropic. We found no correlation between these viral characteristics and the HIV outcomes of time to clinical AIDS or death and/or a CD4 cell count <200 cells/microL... - Lack of associations between HLA class II alleles and resistance to HIV-1 infection among white, non-Hispanic homosexual menChenglong Liu
School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
J Acquir Immune Defic Syndr 37:1313-7. 2004..Other genetic factors in the HLA class II-TAP region of the major histocompatibility complex might be involved... - Seroprevalence of human herpesvirus 8 infection in Northern ThailandNora Chen
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 39:1052-8. 2004..CONCLUSION: Despite the rarity of KS among patients with AIDS in Thailand, HHV-8 infections are common and do not appear to be frequently transmitted sexually in these populations...
Research Grants
- Center/Coordination, Analysis and Management/MACS-Part BLisa Jacobson; Fiscal Year: 2007..abstract_text> ..