Research Topics
| Judy HuangSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Predictors of surgery-free outcome in adult endoscopic third ventriculostomyGraeme F Woodworth
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
World Neurosurg 78:312-7. 2012..We analyze patient, radiographic, and operative factors associated with CSF diversion surgery-free outcomes after ETV...
Prior CSF shunting increases the risk of endoscopic third ventriculostomy failure in the treatment of obstructive hydrocephalus in adultsGraeme Woodworth
The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Neurol Res 29:27-31. 2007..The value of concurrent ETV and ventriculoperitoneal (VP) shunting in patients with frequent shunt failure remains unstudied...- Predictors of ambulatory function after surgical resection of intramedullary spinal cord tumorsGraeme F Woodworth
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurosurgery 61:99-105; discussion 105-6. 2007..Although previous research is limited, identifying reliable predictors of functional status after tumor resection would be clinically useful for perioperative modification strategies... - Frameless image-guided stereotactic brain biopsy procedure: diagnostic yield, surgical morbidity, and comparison with the frame-based techniqueGraeme F Woodworth
Department of Neurosurgery, The Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
J Neurosurg 104:233-7. 2006..Few authors have evaluated this procedure, analyzed preoperative predictors of diagnostic yield, or explored the differences in diagnostic yield and morbidity rate between the frameless and frame-based techniques... - Evaluation of a distal pericallosal aneurysm visualized with 3-dimensional digital subtraction angiography: case report and treatment implicationsGraeme F Woodworth
Department of Neurosurgery, Division of Interventional Neuroradiology, Johns Hopkins School of Medicine, 1017 S Bouldin Street, Baltimore, MD 21224, USA
Surg Neurol 64:321-4. 2005..This was then revealed to be a saccular bifurcation aneurysm by 3D-DSA. This additional information changed the treatment plan for this patient from medical management to a surgical approach... - Selective versus routine intraoperative shunting during carotid endarterectomy: a multivariate outcome analysisGraeme F Woodworth
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA
Neurosurgery 61:1170-6; discussion 1176-7. 2007..No studies have assessed the independent association of selective versus routine intraluminal shunting to outcomes after CEA... - Cerebrospinal fluid drainage and dynamics in the diagnosis of normal pressure hydrocephalusGraeme F Woodworth
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurosurgery 64:919-25; discussion 925-6. 2009..We examined the utility of CSF drainage and CSF pressure (Pcsf) dynamics in predicting response to CSF shunting for patients with INPH... - Impact of changes in intraoperative somatosensory evoked potentials on stroke rates after clipping of intracranial aneurysmsRobert T Wicks
The Johns Hopkins University School of Medicine, Department of Neurosurgery, Baltimore, Maryland, USA
Neurosurgery 70:1114-24; discussion 1124. 2012..Somatosensory evoked potential (SSEP) monitoring is used during intracranial aneurysm surgery to track the effects of anesthesia, surgical manipulation, and temporary clipping... - A single center comparison of coiling versus stent assisted coiling in 90 consecutive paraophthalmic region aneurysmsGeoffrey P Colby
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
J Neurointerv Surg 4:116-20. 2012..However, further investigation into the durability and outcomes of stent assisted coiling procedures is required... - Surgical treatment of cranial arteriovenous malformations and dural arteriovenous fistulasGustavo Pradilla
Division of Cerebrovascular Neurosurgery, Department of Neurosurgery, The Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
Neurosurg Clin N Am 23:105-22. 2012..When performed, however, microsurgical obliteration of DAVFs is associated with excellent outcomes as well. This article reviews the current state of microsurgical treatment of AVMs and DAVFs... - Inflammation and cerebral vasospasm after subarachnoid hemorrhageGustavo Pradilla
Division of Cerebrovascular Neurosurgery, Department of Neurosurgery, The Johns Hopkins University School of Medicine, Meyer Building 8 181, 600 North Wolfe Street, Baltimore, MD 21287, USA
Neurosurg Clin N Am 21:365-79. 2010.... 
Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemiaPiotr Walczak
Division of MR Research, Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 217 Traylor, 720 Rutland Ave, Baltimore, MD 21205 2195, USA
Stroke 39:1569-74. 2008..We assessed the suitability of laser Doppler flow (LDF) signal measurements and magnetic resonance (MR) imaging for noninvasive dual monitoring of targeted IA cell delivery...- Historical perspective of treatments of cranial arteriovenous malformations and dural arteriovenous fistulasGeoffrey P Colby
Department of Neurosurgery, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
Neurosurg Clin N Am 23:15-25. 2012..It also describes modern therapeutic options, including microsurgical, endovascular, and radiosurgery techniques... - Cost comparison of endovascular treatment of anterior circulation aneurysms with the pipeline embolization device and stent-assisted coilingGeoffrey P Colby
Department of Neurosurgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurosurgery 71:944-48; discussion 948-50. 2012..However, stent-coiling incurs significant equipment and implant costs... - Comparison of tertiary-center aneurysm location frequencies in 400 consecutive cases: Decreasing incidence of posterior communicating artery region aneurysmsAlexander L Coon
Department of Neurosurgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, 600 N Wolfe Street, Meyer 8 181, Baltimore, MD 21287, USA
Surg Neurol Int 2:152. 2011..The authors hypothesized that this would be reflected in changes in the location frequencies of aneurysms treated now compared to before the widespread institution of endovascular coiling... - Hyperglycemia independently increases the risk of perioperative stroke, myocardial infarction, and death after carotid endarterectomyMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Neurosurgery 58:1066-73; discussion 1066-73. 2006..Strict glucose control should be attempted before surgery to minimize the risk of morbidity and mortality after CEA... - Role of inflammation (leukocyte-endothelial cell interactions) in vasospasm after subarachnoid hemorrhageKaisorn L Chaichana
Division of Cerebrovascular Neurosurgery, Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
World Neurosurg 73:22-41. 2010..This phenomenon was first described more than 50 years ago, but only recently has the role of inflammation in this condition become better understood... - Simplified quantitative description of amide proton transfer (APT) imaging during acute ischemiaPhillip Zhe Sun
Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Magn Reson Med 57:405-10. 2007..The results showed an optimal RF strength of 0.75 microT for our particular coil setup, and a maximally obtainable APT ratio difference of 2.9%+/-0.3% between ischemic and normal brain regions... - Dural arteriovenous fistulas: epidemiology and clinical presentationKaisorn L Chaichana
Cerebrovascular Neurosurgery, Department of Neurosurgery, The Johns Hopkins Hospital, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
Neurosurg Clin N Am 23:7-13. 2012..This places an emphasis on promptly suspecting and diagnosing these lesions. This review highlights the etiology, epidemiology, clinical presentation, and clinical course of patients with intracranial DAVFs... - Simvastatin for the prevention of symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage: a single-institution prospective cohort studyMatthew J McGirt
Department of Neurosurgery, Johns Hopkins University Hospital, Baltimore, Maryland, USA
J Neurosurg 110:968-74. 2009..The authors conducted a prospective observational study to determine whether a standardized regimen of simvastatin would reduce the incidence of cerebral vasospasm and improve neurological outcomes in patients with aSAH... - Intra-arterial intraoperative computed tomography angiography guided navigation: a new technique for localization of vascular pathologyShaan M Raza
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Neurosurgery 71:ons240-52; discussion ons252. 2012..We introduce the technique of intraoperative computed tomography angiography (iCTA) with an intra-arterial injection for surgical navigation... - 17β-estradiol attenuates breakdown of blood-brain barrier and hemorrhagic transformation induced by tissue plasminogen activator in cerebral ischemiaMingchang Li
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Neurobiol Dis 44:277-83. 2011..These findings suggest a potential role for estrogen in thrombolytic treatment for ischemic stroke... - Microsurgical clipping and endovascular coiling of intracranial aneurysms: a critical review of the literaturePushpa V Raja
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Neurosurgery 62:1187-202; discussion 1202-3. 2008..The objective of this review is to weigh evidence for the efficacy of endovascular coiling compared with microsurgical clipping based on published head-to-head comparisons... - Intracranial aneurysms in the pediatric population: case series and literature reviewJudy Huang
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Surg Neurol 63:424-32; discussion 432-3. 2005..Pediatric intracranial aneurysms occur more commonly in male patients and have a predilection for the terminal ICA bifurcation... - The radiosurgical treatment of arteriovenous malformations: obliteration, morbidities, and performance statusDaniel Q Sun
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, MD, USA
Int J Radiat Oncol Biol Phys 80:354-61. 2011..This study examined the single-center treatment outcomes of arteriovenous malformations (AVMs) of the brain using stereotactic radiosurgery, with regard to obliteration, predictive factors, morbidities, and patient performance status... - Aortic arch injection with C-arm cone beam CT for radiosurgery treatment planning of cerebral arteriovenous malformations: technical noteMartin G Radvany
The Johns Hopkins University School of Medicine, Division of Interventional Neuroradiology, Baltimore, Maryland 21287, USA
J Neurointerv Surg 4:e28. 2012..In some instances an AVM will derive its blood supply from more than one main cervical artery (carotid and/or vertebral artery) and a single-vessel injection will not adequately demonstrate the entire AVM nidus... - Inflammation in stroke and focal cerebral ischemiaJudy Huang
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Surg Neurol 66:232-45. 2006..Exploring these pathophysiological mechanisms underlying ischemic tissue damage may direct rational drug design in the therapeutic treatment of stroke... - Femoral access in 100 consecutive subarachnoid hemorrhage patients: the "craniotomy" of endovascular neurosurgeryAlexandra R Paul
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, MD, USA
BMC Res Notes 3:285. 2010..We sought to characterize the location of the CFA bifurcation along with the presence of significant atherosclerosis or iliac tortuosity in a contemporary series of subarachnoid hemorrhage (SAH) patients... - Detection of the ischemic penumbra using pH-weighted MRIPhillip Zhe Sun
Division of MRI Research, Neurosection, Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Cereb Blood Flow Metab 27:1129-36. 2007..These first results show that pHWI can provide information complementary to PWI and DWI in the delineation of ischemic tissue... - The syndrome of hydrocephalus in young and middle-aged adults (SHYMA)John A Cowan
Department of Neurosurgery, Baltimore, MD, USA
Neurol Res 27:540-7. 2005..Despite the subtlety of clinical signs, CSF diversion treatment is effective at resolving symptomatology... - Dural prostate adenocarcinoma metastasis with subdural hematoma mimicking the appearance of an epidural hematomaMichael J Dorsi
Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD, United States
Clin Neurol Neurosurg 112:501-4. 2010..Here we describe the clinical presentation, evaluation and surgical intervention of a patient with a dural prostate carcinoma metastasis with chronic subdural hematoma mimicking an epidural hematoma... - Occurrence of perimesencephalic subarachnoid hemorrhage during pregnancyKaren G Hirsch
Department of Neurology, Johns Hopkins University School of Medicine, Meyer 8 140, 600 N Wolfe St, Baltimore, MD, USA
Neurocrit Care 10:339-43. 2009..Risk factors may include hypertension and tobacco use, but it has not previously been reported during pregnancy... - Delayed tolerance with repetitive transient focal ischemic preconditioning in the mouseJian Zhang
Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Blalock 1404, Baltimore, MD 21287, USA
Stroke 39:967-74. 2008..The present objective was to develop an ischemic preconditioning (IPC) model of delayed tolerance in the mouse based on repetitive, transient middle cerebral artery occlusion (MCAO)... - Diagnosis, treatment, and analysis of long-term outcomes in idiopathic normal-pressure hydrocephalusMatthew J McGirt
Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Neurosurgery 57:699-705; discussion 699-705. 2005..CSF shunting is safe and effective for INPH with a long-term shunt response rate of 75%. Independent predictors of improvement are the presence of gait impairment as the dominant symptom and shorter duration of symptoms... - Baseline neuropsychological profile and cognitive response to cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalusGeorge Thomas
Adult Hydrocephalus Program, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Dement Geriatr Cogn Disord 20:163-8. 2005.... - Cerebrospinal fluid shunt placement for pseudotumor cerebri-associated intractable headache: predictors of treatment response and an analysis of long-term outcomesMatthew J McGirt
Departments of Neurosurgery, Ophthalmology, and Neurology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Neurosurg 101:627-32. 2004..Using ventricular shunts in patients with papilledema or symptoms lasting less than 2 years should be considered for those with pseudotumor cerebri-associated intractable headache... - Accuracy of frameless and frame-based image-guided stereotactic brain biopsy in the diagnosis of glioma: comparison of biopsy and open resection specimenGraeme Woodworth
Departments of Neurosurgery and Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Neurol Res 27:358-62. 2005..Large tumor volume had a higher incidence of non-concordance. Increasing the number of specimens taken through the long dimension of large tumors may improve diagnostic accuracy...