Research Topics
Genomes and GenesSpecies | Han Yao HuangSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
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Detail Information
Publications
Impact of pill organizers and blister packs on adherence to pill taking in two vitamin supplementation trialsH Y Huang
Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205 2223, USA
Am J Epidemiol 152:780-7. 2000..In summary, use of blister packs, but not pill organizers, improved adherence as measured by pill counts among those with lower adherence. Neither pill delivery system improved adherence as measured by serum vitamin levels...
Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based populationHan Yao Huang
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
BMC Genet 8:7. 2007..The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF...
Multivitamin/Mineral supplements and prevention of chronic disease: executive summaryHan-Yao Huang
Department of Epidemiology, John Hopkins Bloomberg School of Public Health, Baltimore, MD 21205-2223, USA
Am J Clin Nutr 85:265S-268S. 2007
The efficacy and safety of multivitamin and mineral supplement use to prevent cancer and chronic disease in adults: a systematic review for a National Institutes of Health state-of-the-science conferenceHan Yao Huang
Bloomberg School of Public Health and the School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205 2223, USA
Ann Intern Med 145:372-85. 2006..Multivitamin and mineral supplements are the most commonly used dietary supplements in the United States...
The effects of vitamin C supplementation on serum concentrations of uric acid: results of a randomized controlled trialHan Yao Huang
Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 52:1843-7. 2005..Previous studies have suggested a uricosuric effect of vitamin C. Whether vitamin C reduces serum uric acid is unknown. We undertook this study to determine the effects of vitamin C supplementation on serum uric acid concentrations...
Supplementation of diets with alpha-tocopherol reduces serum concentrations of gamma- and delta-tocopherol in humansHan Yao Huang
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Nutr 133:3137-40. 2003..In view of the potential benefits of gamma- and delta-tocopherol, the efficacy of alpha-tocopherol supplementation may be reduced due to decreases in serum gamma- and delta-tocopherol levels. Additional research is clearly warranted...
Prospective study of antioxidant micronutrients in the blood and the risk of developing prostate cancerHan Yao Huang
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 2223, USA
Am J Epidemiol 157:335-44. 2003..Findings do not replicate previous reports of a protective association between lycopene and prostate cancer, but they suggest potential chemopreventive effects of gamma-tocopherol on prostate cancer...
Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trialHan Yao Huang
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore 21205 2223, USA
Am J Clin Nutr 76:549-55. 2002..Evidence predominantly from in vitro studies suggests that antioxidant vitamins can prevent lipid peroxidation and that vitamin C and vitamin E have synergistic effects. However, in vivo evidence in support of these hypotheses is sparse...
Single nucleotide polymorphisms in inflammation-related genes and mortality in a community-based cohort in Washington County, MarylandLisa Gallicchio
Prevention and Research Center, Weinberg Center for Women s Health and Medicine, Mercy Medical Center, Baltimore, MD 21202, USA
Am J Epidemiol 167:807-13. 2008..The authors' findings from this community-based prospective cohort study suggest that the selected SNPs are not associated with overall or cause-specific death, although CRP genotypes may be associated with systemic inflammation...
Body mass, polymorphisms in obesity-related genes, and the risk of developing breast cancer among women with benign breast diseaseLisa Gallicchio
Prevention and Research Center, The Weinberg Center for Women s Health and Medicine, Mercy Medical Center, 227 St Paul Place, Baltimore, MD 21202, USA
Cancer Detect Prev 31:95-101. 2007....
N-acetyltransferase 2 (NAT2) genotypes, cigarette smoking, and the risk of breast cancerAnthony J Alberg
Department of Epidemiology, Room E6132B, The Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Cancer Detect Prev 28:187-93. 2004..The results for smoking were consistent with an inactivation role for NAT2 in breast cancer...
Single nucleotide polymorphisms in obesity-related genes and all-cause and cause-specific mortality: a prospective cohort studyLisa Gallicchio
The Prevention and Research Center, The Weinberg Center for Women s Health and Medicine, Mercy Medical Center, Baltimore, Maryland 21202, USA
BMC Med Genet 10:103. 2009..We also examined the associations between the SNPs and body mass index (BMI) and change in BMI over time...
Genetic polymorphisms of peroxisome proliferator-activated receptors and the risk of cardiovascular morbidity and mortality in a community-based cohort in washington county, MarylandL Gallicchio
Prevention and Research Center, Weinberg Center for Women s Health and Medicine, Mercy Medical Center, 227 Street Paul Place, 6th Floor, Baltimore, MD 21202, USA
PPAR Res 2008:276581. 2008..Future studies should be conducted to confirm these findings and to explore the associations in populations with greater racial and ethnic diversity...
Association between alpha-tocopherol, gamma-tocopherol, selenium, and subsequent prostate cancerK J Helzlsouer
Department of Epidemiology, The Johns Hopkins School of Hygiene and Public Health, Baltimore, MD 21205, USA
J Natl Cancer Inst 92:2018-23. 2000..S. diet and the second most common tocopherol in human serum. A nested case-control study was conducted to examine the associations of alpha-tocopherol, gamma-tocopherol, and selenium with incident prostate cancer...
A community-based study of cigarette smoking behavior in relation to variation in three genes involved in dopamine metabolism: Catechol-O-methyltransferase (COMT), dopamine beta-hydroxylase (DBH) and monoamine oxidase-A (MAO-A)Meredith S Shiels
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
Prev Med 47:116-22. 2008..The association between common polymorphisms of these genes and smoking behavior was assessed among 10,059 Caucasian volunteers in Washington County, MD in 1989...
Measurement of cyclin E genomic copy number and strand length in cell-free DNA distinguish malignant versus benign effusionsRitu Salani
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
Clin Cancer Res 13:5805-9. 2007..We hypothesized that analysis of both DNA copy number and strand length of cell-free DNA from an amplified chromosomal region could improve the diagnosis of malignant diseases in body fluids...
Customized diets for cancer prevention according to genetic polymorphisms: are we ready yet?Han Yao Huang
J Natl Cancer Inst 98:1590-1. 2006
Nonsteroidal antiinflammatory drugs, cyclooxygenase polymorphisms, and the risk of developing breast carcinoma among women with benign breast diseaseLisa Gallicchio
Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21202, USA
Cancer 106:1443-52. 2006....
C47T polymorphism in manganese superoxide dismutase (MnSOD), antioxidant intake and survivalJeanine M Genkinger
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, MA, United States
Mech Ageing Dev 127:371-7. 2006..A C47T transition in the MnSOD gene may affect the enzyme's distribution to the mitochondrion, a site of high oxidative stress. We examined the association between this polymorphism and survival...
Antioxidant supplements and mortalityHan-Yao Huang
JAMA 298:400-1; author reply 402-3. 2007
Increased plasma DNA integrity in cancer patientsBrant G Wang
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
Cancer Res 63:3966-8. 2003..59. Our findings suggest that increased DNA integrity in plasma DNA is associated with cancer, and measurement of DNA integrity may provide a simple and inexpensive measure for cancer detection...
