Rudolf Hoehn-Saric

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Neural correlates of derived relational responding on tests of stimulus equivalence
    Michael W Schlund
    Department of Behavioral Psychology, Kennedy Krieger Institute, Baltimore MD, USA
    Behav Brain Funct 4:6. 2008
  2. ncbi request reprint Cerebral blood flow in obsessive-compulsive patients with major depression: effect of treatment with sertraline or desipramine on treatment responders and non-responders
    R Hoehn-Saric
    Department of Psychiatry, Johns Hopkins School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Psychiatry Res 108:89-100. 2001
  3. ncbi request reprint Effect of worry on regional cerebral blood flow in nonanxious subjects
    Rudolf Hoehn-Saric
    Department of Psychiatry, Johns Hopkins School of Medicine, Room 117, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Psychiatry Res 140:259-69. 2005
  4. ncbi request reprint Somatic symptoms and physiologic responses in generalized anxiety disorder and panic disorder: an ambulatory monitor study
    Rudolf Hoehn-Saric
    Department of Psychiatry, The Johns Hopkins Medical Institutions, Baltimore, MD 21287 7113, USA
    Arch Gen Psychiatry 61:913-21. 2004
  5. ncbi request reprint Effects of citalopram on worry and brain activation in patients with generalized anxiety disorder
    Rudolf Hoehn-Saric
    Department of Psychiatry, Johns Hopkins School of Medicine, 115 Meyer Building, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Psychiatry Res 131:11-21. 2004
  6. ncbi request reprint Demographic and clinical characteristics associated with treatment status in family members with obsessive-compulsive disorder
    Bernadette Cullen
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Depress Anxiety 25:218-24. 2008
  7. pmc Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder
    Virginia L Willour
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21287, USA
    Am J Hum Genet 75:508-13. 2004
  8. ncbi request reprint The identification of OCD-related subgroups based on comorbidity
    Gerald Nestadt
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
    Biol Psychiatry 53:914-20. 2003
  9. ncbi request reprint Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study
    Jack F Samuels
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 4 181, Baltimore, MD 21287 7228, USA
    Behav Res Ther 45:673-86. 2007
  10. ncbi request reprint Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study
    Jack Samuels
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, School of Medicine, 600 N Wolfe St, Meyer 4 181, Baltimore, MD 21287 7228, USA
    Am J Psychiatry 164:493-9. 2007

Detail Information

Publications26

  1. pmc Neural correlates of derived relational responding on tests of stimulus equivalence
    Michael W Schlund
    Department of Behavioral Psychology, Kennedy Krieger Institute, Baltimore MD, USA
    Behav Brain Funct 4:6. 2008
    ..abstract:..
  2. ncbi request reprint Cerebral blood flow in obsessive-compulsive patients with major depression: effect of treatment with sertraline or desipramine on treatment responders and non-responders
    R Hoehn-Saric
    Department of Psychiatry, Johns Hopkins School of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Psychiatry Res 108:89-100. 2001
    ..Thus, higher prefrontal and subcortical activity was associated with better response to drug treatment. In addition, clinical change, but not the administration of medication as such, was associated with a decrease of prefrontal rCBF...
  3. ncbi request reprint Effect of worry on regional cerebral blood flow in nonanxious subjects
    Rudolf Hoehn-Saric
    Department of Psychiatry, Johns Hopkins School of Medicine, Room 117, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Psychiatry Res 140:259-69. 2005
    ..Activity of the left orbito-frontal gyrus was negatively correlated with activity of the amygdalae. The results support the hypothesis that worry-induced prefrontal activity suppresses affect-related subcortical regions...
  4. ncbi request reprint Somatic symptoms and physiologic responses in generalized anxiety disorder and panic disorder: an ambulatory monitor study
    Rudolf Hoehn-Saric
    Department of Psychiatry, The Johns Hopkins Medical Institutions, Baltimore, MD 21287 7113, USA
    Arch Gen Psychiatry 61:913-21. 2004
    ..Physiologic responses of patients with anxiety disorders to everyday events are poorly understood...
  5. ncbi request reprint Effects of citalopram on worry and brain activation in patients with generalized anxiety disorder
    Rudolf Hoehn-Saric
    Department of Psychiatry, Johns Hopkins School of Medicine, 115 Meyer Building, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Psychiatry Res 131:11-21. 2004
    ..These findings support the clinical impression that GAD patients overreact to both pathology-specific and non-specific cues and that the reduction of anxiety attenuates the response to both types of cues...
  6. ncbi request reprint Demographic and clinical characteristics associated with treatment status in family members with obsessive-compulsive disorder
    Bernadette Cullen
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Depress Anxiety 25:218-24. 2008
    ..Clinical factors are predominant in predicting treatment status in family members with OCD. Although the mean duration from onset of symptoms to treatment was long, younger family members appear to receive treatment sooner...
  7. pmc Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder
    Virginia L Willour
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21287, USA
    Am J Hum Genet 75:508-13. 2004
    ..046 and .02, respectively) for association...
  8. ncbi request reprint The identification of OCD-related subgroups based on comorbidity
    Gerald Nestadt
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland, USA
    Biol Psychiatry 53:914-20. 2003
    ..This study employed latent class analysis (LCA) to explore whether there are underlying clinical constructs that distinguish "OCD-related" subgroups...
  9. ncbi request reprint Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study
    Jack F Samuels
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 4 181, Baltimore, MD 21287 7228, USA
    Behav Res Ther 45:673-86. 2007
    ..The findings suggest that hoarding behavior may help differentiate a distinct clinical subgroup of people with OCD and may aggregate in some OCD families. Indecision may be a risk factor for hoarding in these families...
  10. ncbi request reprint Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study
    Jack Samuels
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, School of Medicine, 600 N Wolfe St, Meyer 4 181, Baltimore, MD 21287 7228, USA
    Am J Psychiatry 164:493-9. 2007
    ..The objective of this study was to determine whether there are chromosomal regions specifically linked to compulsive hoarding behavior in families with obsessive-compulsive disorder...
  11. pmc Sex-specific clinical correlates of hoarding in obsessive-compulsive disorder
    Jack F Samuels
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 4 181, Baltimore, MD 21287 7228, USA
    Behav Res Ther 46:1040-6. 2008
    ..These findings indicate that specific clinical correlates of hoarding in OCD are different in men and women and may reflect sex-specific differences in the course, expression, and/or etiology of hoarding behavior in OCD...
  12. pmc Generalized anxiety modulates frontal and limbic activation in major depression
    Michael W Schlund
    Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Behav Brain Funct 8:8. 2012
    ..Anxiety is relatively common in depression and capable of modifying the severity and course of depression. Yet our understanding of how anxiety modulates frontal and limbic activation in depression is limited...
  13. doi request reprint Social and communication difficulties and obsessive-compulsive disorder
    Bernadette Cullen
    Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Psychopathology 41:194-200. 2008
    ..In this study we sought to establish if there is any association between the presence of abnormal pragmatic behaviors and OCD and whether this association delineates a familial subtype of OCD...
  14. doi request reprint Functional MRI of the amygdala and bed nucleus of the stria terminalis during conditions of uncertainty in generalized anxiety disorder
    Michael A Yassa
    Department of Psychological and Brain Sciences, Johns Hopkins University, 3400 N Charles St, Baltimore, MD 21218 2686, USA
    J Psychiatr Res 46:1045-52. 2012
    ..Future studies are needed to investigate the temporal dynamics of activation and deactivation in these regions...
  15. pmc Carbon dioxide provocation of anxiety and respiratory response in bipolar disorder
    Dean F MacKinnon
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
    J Affect Disord 99:45-9. 2007
    ..Frequent bipolar/panic comorbidity implies bipolar individuals may experience CO2-provoked anxiety and changes in respiratory patterns similar to those experienced by individuals with panic disorder...
  16. doi request reprint Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoarding
    Kung Yee Liang
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Am J Med Genet B Neuropsychiatr Genet 147:1000-2. 2008
    ....
  17. pmc New knowledge derived from learned knowledge: functional-anatomic correlates of stimulus equivalence
    Michael W Schlund
    Department of Behavioral Psychology, Kennedy Krieger Institute 707 N Broadway, Baltimore, MD 21205, USA
    J Exp Anal Behav 87:287-307. 2007
    ..Collectively, the findings extend the role of frontal-subcortical and frontal-parietal networks to derived conditional relations and suggest that regional involvement varies with the type of derived conditional relation...
  18. ncbi request reprint Physiological arousal in females with fragile X or Turner syndrome
    Cynthia S Keysor
    Department of Psychiatry, Kennedy Krieger Institute, Baltimore, MD 21211, USA
    Dev Psychobiol 41:133-46. 2002
    ..Factors potentially associated with heightened arousal in fragile X and Turner syndrome are discussed...
  19. pmc The OCD collaborative genetics study: methods and sample description
    Jack F Samuels
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 7228, USA
    Am J Med Genet B Neuropsychiatr Genet 141:201-7. 2006
    ....
  20. ncbi request reprint Familiality of factor analysis-derived YBOCS dimensions in OCD-affected sibling pairs from the OCD Collaborative Genetics Study
    Gregor Hasler
    Laboratory of Clinical Science, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
    Biol Psychiatry 61:617-25. 2007
    ..While factor-analytic studies have found consistent, clinically meaningful OCD symptom dimensions, there have been only limited attempts to evaluate the familiality and potential genetic basis of such dimensions...
  21. pmc Further development of YBOCS dimensions in the OCD Collaborative Genetics study: symptoms vs. categories
    Anthony Pinto
    Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, Providence, RI 02906, USA
    Psychiatry Res 160:83-93. 2008
    ..The results support investigation of this multidimensional model in OCD genetic linkage studies...
  22. ncbi request reprint Clinical correlates of recurrent major depression in obsessive-compulsive disorder
    Jin Pyo Hong
    Department of Psychiatry, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea
    Depress Anxiety 20:86-91. 2004
    ..In a multiple logistic regression model, only early age of OCD diagnosis was significantly associated with RDD. Early age at onset of OCD increases the risk of depressive disorder in individuals with OCD...
  23. pmc Arousal modulation in females with fragile X or Turner syndrome
    Jane Roberts
    Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Autism Dev Disord 38:20-7. 2008
    ..Taken together, our findings suggest that distinct profiles of arousal modulation might be associated with cognitive deficits in these syndrome populations...
  24. ncbi request reprint Proton magnetic resonance spectroscopy in obsessive-compulsive disorder: a pilot investigation comparing treatment responders and non-responders
    Mona A Mohamed
    The Johns Hopkins University School of Medicine, Russell H Morgan Department of Radiology and Radiological Science, Baltimore, MD, United States
    Psychiatry Res 156:175-9. 2007
    ..Abnormal neuronal metabolism in the right basal ganglia and right thalamus may be indicating lack of response to treatment to selective serotonin reuptake inhibitor...
  25. ncbi request reprint Predicting treatment response in obsessive-compulsive disorder
    Robin A Hurley
    Mental Health Care Line, Houston Veterans Affairs Medical Center, Houston, Texas, USA
    J Neuropsychiatry Clin Neurosci 14:249-53. 2002
  26. ncbi request reprint Facial hyperhidrosis-induced social fear alleviated with topiramate
    Rudolf Hoehn-Saric
    J Clin Psychiatry 67:1157. 2006