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Genomes and Genes | M HaasSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
CR1/CR2 deficiency alters IgG3 autoantibody production and IgA glomerular deposition in the MRL/lpr model of SLESusan A Boackle
Department of Medicine and Immunology, Division of Rheumatology, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Autoimmunity 37:111-23. 2004..Together these data support the concept that alterations in CR1/CR2 expression or function affect the regulation of autoantibody production and/or clearance and may have clinical consequences...- Histology and immunohistology of IgA nephropathyMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Nephrol 18:676-80. 2005..This review examines the histologic diversity as well as the immunohistologic features of IgA nephropathy... - C4d staining of perioperative renal transplant biopsiesMark Haas
Department of Pathology, Johns Hopkins University, Baltimore, MD 21287, USA
Transplantation 74:711-7. 2002..However, in other studies, PTC C4d deposits were noted in more than 40% of renal transplant biopsies performed for graft dysfunction and capillary C4d deposition in heart transplants may result from ischemic injury... - Acute renal allograft rejection with intimal arteritis: histologic predictors of response to therapy and graft survivalMark Haas
Department of Pathology and Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Kidney Int 61:1516-26. 2002.... 
Collapsing glomerulopathy: many means to a similar endM Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Kidney Int 73:669-71. 2008....- Arteriosclerosis in kidneys from healthy live donors: comparison of wedge and needle core perioperative biopsiesMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Pathology 712, Baltimore, MD 21287, USA
Arch Pathol Lab Med 132:37-42. 2008..There are many studies of histopathologic changes in deceased donor kidneys and how these changes affect subsequent graft function; most are based on wedge rather than needle core biopsies... - Glomerular tip lesion in minimal change nephropathy: a study of autopsies before 1950Mark Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Am J Kidney Dis 39:1168-75. 2002..These findings suggest that the glomerular tip lesion can occur in MCN and most likely represents a response to heavy proteinuria that is not disease specific... - IgA nephropathy in children and adults: comparison of histologic features and clinical outcomesMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Nephrol Dial Transplant 23:2537-45. 2008..Some of this variability may be related to differences in histologic severity of cohorts of patients diagnosed as children versus adults... - Subclinical acute antibody-mediated rejection in positive crossmatch renal allograftsM Haas
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Am J Transplant 7:576-85. 2007..5 +/- 2.5 versus 1.0 +/- 2.0, p = 0.01) than that in 24 recipients of HLA-incompatible grafts with no AMR over a similar interval (360 +/- 117 days), suggesting that subclinical AMR may contribute to development of CAN... - Thin glomerular basement membrane nephropathy: incidence in 3471 consecutive renal biopsies examined by electron microscopyMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Arch Pathol Lab Med 130:699-706. 2006.... - Hypertension, race, and glomeruli: more than simply a numbers gameM Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Kidney Int 69:640-2. 2006..However, although studies show a clear association between hypertension and glomerular number in whites, the situation in African-Americans appears more complex... - Immune complex deposits in ANCA-associated crescentic glomerulonephritis: a study of 126 casesMark Haas
Department of Pathology and Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Kidney Int 65:2145-52. 2004.... - HIV-associated immune complex glomerulonephritis with "lupus-like" features: a clinicopathologic study of 14 casesMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Kidney Int 67:1381-90. 2005..Data regarding clinical outcomes in patients with this form of glomerulonephritis are very limited... 
C4d deposition without rejection correlates with reduced early scarring in ABO-incompatible renal allograftsMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Pathology 712, Baltimore, MD 21287, USA
J Am Soc Nephrol 20:197-204. 2009....- Isometric tubular epithelial vacuolization in renal allograft biopsy specimens of patients receiving low-dose intravenous immunoglobulin for a positive crossmatchMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Pathology 712, Baltimore, MD 21287, USA
Transplantation 78:549-56. 2004..A common finding in biopsy specimens of these allografts is isometric vacuolization of proximal tubular epithelium. This finding presents a diagnostic dilemma because it may occur secondary to IVIG treatment or tacrolimus nephrotoxicity... - Etiologies and outcome of acute renal insufficiency in older adults: a renal biopsy study of 259 casesM Haas
Departments of Pathology and Statistics and the Department of Medicine, Section of Nephrology, The University of Chicago, IL, USA
Am J Kidney Dis 35:433-47. 2000.... - The Na-K-Cl cotransporter of secretory epitheliaM Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Annu Rev Physiol 62:515-34. 2000..This review focuses on structure-function relationships within NKCC1 and on recent developments pertaining to NKCC1 regulation at cellular and molecular levels... - ANCA-associated crescentic glomerulonephritis with mesangial IgA depositsM Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Kidney Dis 36:709-18. 2000..The findings suggest an overlap syndrome of ANCA-associated crescentic GN and IgA nephropathy that resembles the former both histologically and in its potential to respond to aggressive therapy if detected relatively early in its course... - Alport syndrome and thin glomerular basement membrane nephropathy: a practical approach to diagnosisMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA
Arch Pathol Lab Med 133:224-32. 2009.... - C4d and C3d staining in biopsies of ABO- and HLA-incompatible renal allografts: correlation with histologic findingsM Haas
Department of Pathology, John Hopkins Medical Institutions, Baltimore, Maryland, USA
Am J Transplant 6:1829-40. 2006.... - The relationship of untreated borderline infiltrates by the Banff criteria to acute rejection in renal allograft biopsiesS M Meehan
Department of Pathology, University of Chicago, Illinois 60637, USA
J Am Soc Nephrol 10:1806-14. 1999.... - Smooth muscle-specific actin levels in the urine of renal transplant recipients: correlation with cyclosporine or tacrolimus nephrotoxicityM Haas
Departments of Pathology and Statistics, University of Chicago, Chicago, IL, USA
Am J Kidney Dis 34:69-84. 1999.... - Drug-induced acute interstitial nephritis in renal allografts: histopathologic features and clinical course in six patientsM A Josephson
Section of Nephrology, Committee on Clinical Pharmacology, Chicago, IL, USA
Am J Kidney Dis 34:540-8. 1999..Drug-induced interstitial nephritis is a reversible lesion that should be considered in the differential diagnosis of acute renal allograft dysfunction... - CD20-positive infiltrates in renal allograft biopsies with acute cellular rejection are not associated with worse graft survivalS M Bagnasco
Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
Am J Transplant 7:1968-73. 2007..Our data do not support association of B cell-rich infiltrates in allograft biopsies and worse outcome in acute rejection type I or II, but do not exclude the possible contribution of B cells to allograft rejection... - Estimating renal function in lupus nephritis: comparison of the Modification of Diet in Renal Disease and Cockcroft Gault equationsN Kasitanon
Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Lupus 16:887-95. 2007..58 mL/min/1.73 m(2), P = 0.003). In lupus nephritis patients, the CG equation was superior to the MDRD equation as an estimate of CrCl. However, both equations lacked precision in patients with CrCl > or = 60 mL/min/1.73 m(2)... - Subclinical rejection in stable positive crossmatch kidney transplant patients: incidence and correlationsE S Kraus
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Transplant 9:1826-34. 2009..Surveillance biopsies during the first year post-transplantation for these high-risk patients uncover clinically occult processes and phenotypes, which without intervention diminish allograft survival and function... - Mycophenolate mofetil as the primary treatment of membranous lupus nephritis with and without concurrent proliferative disease: a retrospective study of 29 casesN Kasitanon
Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Lupus 17:40-5. 2008..However, 12 months of therapy was necessary for best outcomes. Response rate was not different in the presence or absence of a proliferative lesion... - The clinical and pathologic implications of plasmacytic infiltrates in percutaneous renal allograft biopsiesS M Meehan
Department of Pathology, University of Chicago, Chicago, IL 60637, USA
Hum Pathol 32:205-15. 2001..Plasmacytic infiltrates in renal allografts comprise a spectrum of lesions from acute rejection to PTLD, with a generally poor prognosis for long-term graft survival... - The use of antibody to complement protein C5 for salvage treatment of severe antibody-mediated rejectionJ E Locke
Deparmtent of Surgery, John Hopkins Medical Institutions, John Hopkins University, Baltimore, MD, USA
Am J Transplant 9:231-5. 2009..We show a marked decrease in C5b-C9 (MAC) complex deposition in the kidney after the administration of eculizumab... - The utility of splenectomy as rescue treatment for severe acute antibody mediated rejectionJ E Locke
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Transplant 7:842-6. 2007..Five patients underwent immediate splenectomy followed by PP/IVIg and had return of allograft function within 48 h of the procedure. Emergent splenectomy followed by PP/IVIg may be an effective treatment for reversing severe AMR... - Inhibiting the complement system does not reduce injury in renal ischemia reperfusionP Park
Department of Medicine, Section of Nephrology, The University of Chicago, 4841 S Maryland, Chicago, IL 60637, USA
J Am Soc Nephrol 12:1383-90. 2001..Thus, renal IRI in mice may have a partial complement dependence, yet pharmacologic inhibition of the complement system does not seem to be effective, likely because of the presence of other mediator systems that operate in parallel... - Platelets and capillary injury in acute humoral rejection of renal allograftsShane M Meehan
Department of Pathology, University of Chicago Hospitals, IL, USA
Hum Pathol 34:533-40. 2003..Observations in this study suggest that intracapillary platelet activation occurs in response to graft capillary injury from many causes and may not be specific for antibody-mediated rejection... - Granulomatous tubulointerstitial nephritis in the renal allograftS M Meehan
Departments of Pathology and Nephrology, University of Chicago, Chicago, IL, USA
Am J Kidney Dis 36:E27. 2000..To our knowledge, there are no prior reports of granulomatous tubulointerstitial nephritis associated with C albicans and E coli infection or antibiotic therapy in human renal allografts... - ABO antibody titer and risk of antibody-mediated rejection in ABO-incompatible renal transplantationA A R Tobian
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Am J Transplant 10:1247-53. 2010..1% with a specificity of 79.5%. The positive predictive value was 33.3% and the negative predictive value was 91.2%. Most individuals with AMR have an elevated titer, however, the positive predictive value of a high titer for AMR is poor... - The Na-K-Cl cotransportersM Haas
Department of Pathology, The University of Chicago, Illinois 60637, USA
J Bioenerg Biomembr 30:161-72. 1998.... - Altered vitamin D metabolism in type II diabetic mouse glomeruli may provide protection from diabetic nephropathyY Wang
Department of Medicine, The University of Chicago, Chicago, Illinois 60637, USA
Kidney Int 70:882-91. 2006..The podocyte is affected by paracrine and potentially autocrine effects of vitamin D, which may explain why db/db mice are resistant to progressive diabetic nephropathy... - VEGF receptor 2 blockade leads to renal cyst formation in miceS McGrath-Morrow
Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland 21287, USA
Kidney Int 69:1741-8. 2006..Early disruption of VEGFR-2 signaling during the perinatal period results in renal cyst formation, impaired glomerulogenesis, and inflammation. VEGF could be a key link between vascular and cystic changes in kidney cyst formation... - Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritisN Kasitanon
Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, USA
Lupus 15:366-70. 2006..Although hydroxychloroquine is frequently stopped in patients with lupus nephritis, this study suggests it should be started or maintained... - Immune complex glomerulonephritis in C4- and C3-deficient miceR J Quigg
Department of Medicine, The University of Chicago, Illinois 60637, USA
Kidney Int 53:320-30. 1998..These results illustrate the complex interplay between the effects of complement to process immune complexes and to lead to inflammation and tissue injury... - A distinctive pediatric renal neoplasm characterized by epithelioid morphology, basement membrane production, focal HMB45 immunoreactivity, and t(6;11)(p21.1;q12) chromosome translocationP Argani
Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21231 2410, USA
Am J Pathol 158:2089-96. 2001..Cytogenetic analysis reveals the identical t(6;11)(p21.1;q12) chromosome translocation as the sole abnormality in these two tumors, confirming their identity and distinctive nature... - Decay-accelerating factor but not CD59 limits experimental immune-complex glomerulonephritisLihua Bao
Section of Nephrology, The University of Chicago, Chicago, IL 60637, USA
Lab Invest 87:357-64. 2007..Our findings suggest that activation of C3 is strongly associated with experimental ICGN while downstream formation of C5b-9 is of lesser pathogenic importance in this model... - Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failureLihua Bao
Section of Nephrology, Department of Medicine, The University of Chicago, 5841 S Maryland Avenue, MC5100, Chicago, IL 60637, USA
J Am Soc Nephrol 18:811-22. 2007.... - Administration of a soluble recombinant complement C3 inhibitor protects against renal disease in MRL/lpr miceLihua Bao
Section of Nephrology, The University of Chicago, Illinois 60637, USA
J Am Soc Nephrol 14:670-9. 2003..Thus, inhibition of complement activation with Crry-Ig significantly reduces renal disease in MRL/lpr lupus mice. The data support the strategy of using recombinant complement C3 inhibitors to treat human lupus nephritis... - Antibody-mediated rejection in renal allografts: lessons from pathologyLorraine C Racusen
Department of Pathology, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Pathology 712, Baltimore, MD 21287, USA
Clin J Am Soc Nephrol 1:415-20. 2006.... - Cocaine use and hypertensive renal changes in HIV-infected individualsDerek M Fine
Department of Medicine, Johns Hopkins School of Medicine and the Johns Hopkins Hospital, Baltimore, Maryland, USA
Clin J Am Soc Nephrol 2:1125-30. 2007..This study was conducted to evaluate the possible association of cocaine use and histopathologic findings on biopsy in this population... - A complement-dependent model of thrombotic thrombocytopenic purpura induced by antibodies reactive with endothelial cellsGuohui Ren
Section of Nephrology, The University of Chicago, Chicago, Illinois 60637, USA
Clin Immunol 103:43-53. 2002..Antibody-directed complement activation leads to stimulation of platelets, through direct interactions with complement fragments and/or indirectly through endothelial cell activation or injury, with the subsequent development of TTP... - Mouse podocyte complement factor H: the functional analog to human complement receptor 1Jessy J Alexander
Section of Nephrology, University of Chicago, 5841 S Maryland Avenue, MC5100, Chicago, IL 60637, USA
J Am Soc Nephrol 18:1157-66. 2007..Just as in platelets, rodent podocytes seem to use Cfh as the functional surrogate for human complement receptor 1... - Long-term outcome of renal transplantation from older donorsMark Haas
N Engl J Med 354:2071-4; author reply 2071-4. 2006 - Successful retransplantation after renal allograft loss to polyoma virus interstitial nephritisRajiv D Poduval
Division of Nephrology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA
Transplantation 73:1166-9. 2002..Previous graft loss secondary to polyoma virus infection is not a contraindication to retransplantation... - VEGF inhibition and renal thrombotic microangiopathyVera Eremina
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
N Engl J Med 358:1129-36. 2008..These observations provide evidence that glomerular injury in patients who are treated with bevacizumab is probably due to direct targeting of VEGF by antiangiogenic therapy... - IgA-dominant postinfectious glomerulonephritis: a report of 13 cases with common ultrastructural featuresMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Hum Pathol 39:1309-16. 2008.... - Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytesPierce Park
Department of Medicine, Section of Nephrology, University of Chicago, Chicago, Illinois 60637, USA
Am J Physiol Renal Physiol 282:F352-7. 2002..Thus Igs and mature T lymphocytes do not appear to play a significant role in the pathogenesis of IRI in the kidney... - Incidental healed postinfectious glomerulonephritis: a study of 1012 renal biopsy specimens examined by electron microscopyMark Haas
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Hum Pathol 34:3-10. 2003..The recognition of such lesions is potentially important in the interpretation of certain renal biopsy specimens... - Renal biopsy in lupus patients with low levels of proteinuriaLisa Christopher Stine
Divisions of Nephrology and Rheumatology, Johns Hopkins University Department of Medicine, Baltimore, Maryland, USA
J Rheumatol 34:332-5. 2007..We investigated whether patients with lower levels of proteinuria without ARF have significant renal disease and should be routinely biopsied... - Anti-vascular endothelial growth factor receptor-2 antibody accelerates renal disease in the NZB/W F1 murine systemic lupus erythematosus modelHideaki Watanabe
Clin Cancer Res 11:407-9. 2005 - Plasmapheresis, CMV hyperimmune globulin, and anti-CD20 allow ABO-incompatible renal transplantation without splenectomyChristopher J Sonnenday
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Transplant 4:1315-22. 2004..The use of rituximab, allowing avoidance of splenectomy, may further remove one of the significant disincentives to ABOi transplantation, and eliminate the risk of post-splenectomy infections... - Complement factor h limits immune complex deposition and prevents inflammation and scarring in glomeruli of mice with chronic serum sicknessJessy J Alexander
Section of Nephrology, The University of Chicago, 5841 S Maryland Avenue, MC5100, Chicago, IL 60637, USA
J Am Soc Nephrol 16:52-7. 2005..Once deposited in glomeruli, excessive complement activation can lead to glomerular inflammation and the rapid development of a scarring phenotype... - Excellent outcomes after transplantation of deceased donor kidneys with high terminal creatinine and mild pathologic lesionsRichard Ugarte
Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
Transplantation 80:794-800. 2005..CONCLUSIONS: Under select conditions, kidneys from donors with high terminal creatinine can be used safely with excellent results... - Successful renal transplantation across simultaneous ABO incompatible and positive crossmatch barriersDaniel S Warren
The Department of Surgery, The Johns Hopkins University School of Medicine, Balitmore, Maryland, USA
Am J Transplant 4:561-8. 2004..The ability to cross these two barriers simultaneously is clinically important as sensitized patients have often exhausted their blood type compatible living donors during previous transplants... - Sarcoidosis: the nephrologist's perspectiveAdam R Berliner
Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Kidney Dis 48:856-70. 2006 - Specific and durable elimination of antibody to donor HLA antigens in renal-transplant patientsAndrea A Zachary
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205 2222, USA
Transplantation 76:1519-25. 2003..Attempts to deal with this problem have used plasmapheresis to remove antibodies or high-dose pooled immunoglobulin (IVIg) to down-regulate DSA. However, elimination of antibodies by these methods has been limited in duration or scope... - Distinct and separable roles of the complement system in factor H-deficient bone marrow chimeric mice with immune complex diseaseJessy J Alexander
Section of Nephrology, The University of Chicago, AMB S 508, MC 5100, 5841 S Maryland Avenue, Chicago, IL 60637, USA
J Am Soc Nephrol 17:1354-61. 2006..These data show that plasma Cfh limits complement activation in the circulation and other accessible sites such as the glomerulus, whereas platelet Cfh is responsible for immune complex processing... - The glomerular tip lesion: what does it really mean?Mark Haas
Kidney Int 67:1188-9. 2005 - Bartter syndrome complicated by immune complex nephropathy. Case report and literature reviewYahya Sardani
Department of Pediatrics, The University of Chicago Pritzker School of Medicine, 5839 S. Maryland Avenue, Chicago, IL 60637-1470, USA
Pediatr Nephrol 18:913-8. 2003..These findings add to the evidence of a possible association between the congenital syndrome and acquired immune complex nephropathy... - Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr miceLihua Bao
Department of Medicine, Section of Nephrology, University of Chicago, Chicago, IL 60637, USA
J Immunol 168:3601-7. 2002..Thus, long-term complement inhibition reduces renal disease in MRL/lpr mice, which translates into improved survival. MRL/lpr mice in which complement is inhibited still have spontaneous mortality, yet this is not from renal disease... - Signaling through up-regulated C3a receptor is key to the development of experimental lupus nephritisLihua Bao
Section of Nephrology, University of Chicago, Chicago, IL 60637, USA
J Immunol 175:1947-55. 2005..These data illustrate that C3aR is relevant in experimental lupus nephritis and may be a target for therapeutic intervention in the human disease... - CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupusRoman Puliaev
Pathology Department, Uniformed Services University of Health Sciences, Bethesda, MD 20814, USA
J Immunol 181:47-61. 2008.... - The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injurySiddhartha Ghosh
Department of Internal Medicine, Division of Nephrology, Virginia Commonwealth University, Richmond, VA 23298, USA
Am J Med Sci 324:296-304. 2002..We investigated the role of the renin-angiotensin system, particularly with regard to AT1 and AT2 receptor dynamics, in PAN and cholesterol-mediated GS... - Prominent renal expression of a murine leukemia retrovirus in experimental systemic lupus erythematosusJessy J Alexander
Section of Nephrology, The University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637, USA
J Am Soc Nephrol 13:2869-77. 2002..The remarkable upregulation of the EDV transcript only in the setting of active disease suggests this transcript is involved in inflammatory disease... - Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymomaMin Wang
Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Medical School, Houston, Texas, USA
J Neuropathol Exp Neurol 64:875-81. 2005..Overall, the tumors were biologically indolent except for one that recurred and ultimately proved fatal... - Postinfectious glomerulonephritis complicating diabetic nephropathy: a frequent association, but how clinically important?Mark Haas
Hum Pathol 34:1225-7. 2003 - C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonistLihua Bao
Section of Nephrology, The University of Chicago, Chicago, IL, USA
Eur J Immunol 35:2496-506. 2005..These data support an important role for the C5a anaphylatoxin in lupus nephritis, and that blockade of C5aR represents a potentially viable treatment for human lupus nephritis... - Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytesLihua Bao
Section of Nephrology, The University of Chicago, Chicago, Illinois 60637, USA
Kidney Int 62:2010-21. 2002..DAF is present in human glomeruli and on cultured human glomerular visceral epithelial cells (GEC). We studied the distribution and function of rat DAF... - Effects of acid aspiration-induced acute lung injury on kidney functionJeffrey B Hoag
Dept of Medicine and Anesthesiology, The Johns Hopkins Univ, 600 North Wolfe St, Tower 711, Baltimore, MD 21287 8711, USA
Am J Physiol Renal Physiol 294:F900-8. 2008..Kidney injury in large animal models may be more similar to humans and may differ from results seen in small animal models...