Research Topics
Species | Grzegorz T GurdaSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Profiling CCK-mediated pancreatic growth: the dynamic genetic program and the role of STATs as potential regulatorsGrzegorz T Gurda
Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0622, USA
Physiol Genomics 44:14-24. 2012....
Regulator of calcineurin 1 controls growth plasticity of adult pancreasGrzegorz T Gurda
Department of Molecular and Integrative Physiology, The University of Michigan Medical School, Ann Arbor, Michigan, USA
Gastroenterology 139:609-19, 619.e1-6. 2010..CCK-driven pancreatic growth requires calcineurin (CN), which activates Nuclear Factor of Activated T cells (NFATs), but the genetic underpinnings and feedback mechanisms that regulate this response are not known...
Cholecystokinin activates pancreatic calcineurin-NFAT signaling in vitro and in vivoGrzegorz T Gurda
Department of Molecular and Integrative Physiology, The University of Michigan Medical School, Ann Arbor, MI 48109 0622, USA
Mol Biol Cell 19:198-206. 2008..The changes also required calcineurin, as they were blocked by FK506. We conclude that CCK activates NFATs in a calcineurin-dependent manner, both in vitro and in vivo...
Induction of early response genes in trypsin inhibitor-induced pancreatic growthLili Guo
Dept of Molecular and Integrative Physiology, Univ of Michigan Medical School, Ann Arbor, MI 48109 0622, USA
Am J Physiol Gastrointest Liver Physiol 292:G667-77. 2007..These results indicate that camostat feeding induces a spectrum of early response gene expression and AP-1 DNA binding and that these effects are mainly CCK dependent...
Potentiation of the osmosensitive release of taurine and D-aspartate from SH-SY5Y neuroblastoma cells after activation of M3 muscarinic cholinergic receptorsAnne M Heacock
Mental Health Research Institute Laboratories at MSRB II, 1150 West Medical Center Dr, C560, MSRB II, University of Michigan, Ann Arbor, MI 48109-0669, USA
J Pharmacol Exp Ther 311:1097-104. 2004..mAChR-stimulated osmolyte efflux is mediated via a VSOAC and seems to require the activity of a tyrosine kinase...
