D J Grab

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Early invasion of brain parenchyma by African trypanosomes
    Ute Frevert
    Division of Medical Parasitology, Department of Microbiology, New York University School of Medicine, New York, New York, United States of America
    PLoS ONE 7:e43913. 2012
  2. pmc Membrane active chelators as novel anti-African trypanosome and anti-malarial drugs
    Dennis J Grab
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Parasitol Int 62:461-3. 2013
  3. doi Human brain microvascular endothelial cell traversal by Borrelia burgdorferi requires calcium signaling
    D J Grab
    Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Clin Microbiol Infect 15:422-6. 2009
  4. pmc Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells
    Dennis J Grab
    Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS Negl Trop Dis 3:e479. 2009
  5. pmc Using detergent to enhance detection sensitivity of African trypanosomes in human CSF and blood by loop-mediated isothermal amplification (LAMP)
    Dennis J Grab
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    PLoS Negl Trop Dis 5:e1249. 2011
  6. ncbi A role for peripheral blood fibrocytes in Lyme disease?
    D J Grab
    Johns Hopkins School of Medicine, Maryland, Baltimore 21287, USA
    Med Hypotheses 59:1-10. 2002
  7. ncbi Anaplasma phagocytophilum-infected neutrophils enhance transmigration of Borrelia burgdorferi across the human blood brain barrier in vitro
    E Nyarko
    Division of Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Int J Parasitol 36:601-5. 2006

Collaborators

Detail Information

Publications7

  1. pmc Early invasion of brain parenchyma by African trypanosomes
    Ute Frevert
    Division of Medical Parasitology, Department of Microbiology, New York University School of Medicine, New York, New York, United States of America
    PLoS ONE 7:e43913. 2012
    ..Whether individual trypanosomes can act alone or require the interaction from a quorum of parasites remains to be shown. The significance of these findings for disease development is now testable...
  2. pmc Membrane active chelators as novel anti-African trypanosome and anti-malarial drugs
    Dennis J Grab
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Parasitol Int 62:461-3. 2013
    ..While the exact mechanism of action of MACs against intracellular malaria and extracellular African trypanosome parasites has yet to be determined, their potential as antiparasitic agents warrants further investigation...
  3. doi Human brain microvascular endothelial cell traversal by Borrelia burgdorferi requires calcium signaling
    D J Grab
    Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Clin Microbiol Infect 15:422-6. 2009
    ..The data suggest a role for calcium signaling in CNS spirochete invasion through endothelial cell barriers...
  4. pmc Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells
    Dennis J Grab
    Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS Negl Trop Dis 3:e479. 2009
    ....
  5. pmc Using detergent to enhance detection sensitivity of African trypanosomes in human CSF and blood by loop-mediated isothermal amplification (LAMP)
    Dennis J Grab
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    PLoS Negl Trop Dis 5:e1249. 2011
    ..e. 1 per ┬ÁL or 10(3) per mL. We hypothesized that clinical sensitivities that mimic analytical limits based on parasite DNA could be approached or even obtained by simply adding detergent to the samples prior to LAMP assay...
  6. ncbi A role for peripheral blood fibrocytes in Lyme disease?
    D J Grab
    Johns Hopkins School of Medicine, Maryland, Baltimore 21287, USA
    Med Hypotheses 59:1-10. 2002
    ....
  7. ncbi Anaplasma phagocytophilum-infected neutrophils enhance transmigration of Borrelia burgdorferi across the human blood brain barrier in vitro
    E Nyarko
    Division of Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Int J Parasitol 36:601-5. 2006
    ..hy926 cells in the presence of A. phagocytophilum-infected neutrophils than with uninfected neutrophils without affecting endothelial cell integrity. Such a mechanism may contribute to increased blood and tissue spirochete loads...