Research Topics
| David GoldenSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Detail Information
Publications
Patterns of anaphylaxis: acute and late phase features of allergic reactionsDavid B K Golden
Johns Hopkins Allergy Center, Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Novartis Found Symp 257:101-10; discussion 110-5, 157-60, 276-85. 2004..But they occurred in only 6% of anaphylaxis of mixed causes and are uncommon with insect stings. Late phase (biphasic) reactions rarely occur without initial hypotension or airway obstruction...- Long-term outcome after venom immunotherapyDavid B K Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland 21224, USA
Curr Opin Allergy Clin Immunol 10:337-41. 2010..This review will summarize the published evidence for current guidelines and recommendations, with emphasis on long-term outcomes... - Venom immunotherapy reduces large local reactions to insect stingsDavid B K Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, MD, USA
J Allergy Clin Immunol 123:1371-5. 2009..Venom immunotherapy is not recommended because of a low risk for future systemic reaction and unproven efficacy in preventing large local reactions... - Dialyzed venom skin tests for identifying yellow jacket-allergic patients not detected using standard venomDavid B K Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland 21224, USA
Ann Allergy Asthma Immunol 102:47-50. 2009..The chance of a nonspecific intradermal skin test response at venom concentrations greater than 1.0 microg/mL limits the diagnostic range and can interfere with the diagnosis of some affected patients... - What is anaphylaxis?David Bk Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland 21224, USA
Curr Opin Allergy Clin Immunol 7:331-6. 2007..The possible components and steps in the process (proven and hypothetical) are reviewed with respect to their variation and regulation and their potential for therapeutic intervention... - Insect sting anaphylaxisDavid B K Golden
Johns Hopkins University, 733 North Broadway, Baltimore, MD 21205, USA
Immunol Allergy Clin North Am 27:261-72, vii. 2007..Venom immunotherapy is 75% to 98% effective in preventing sting anaphylaxis. Most patients can discontinue treatment after 5 years, with very low residual risk of a severe sting reaction... - Insect allergy in childrenDavid B K Golden
Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Curr Opin Allergy Clin Immunol 6:289-93. 2006..Some aspects of insect sting allergy are unique in children. This review will identify and update the published data that exist pertaining specifically to insect allergy in children... - Clinical and entomological factors influence the outcome of sting challenge studiesDavid B K Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21224, USA
J Allergy Clin Immunol 117:670-5. 2006..The reported frequency of systemic reactions to challenge sting varies greatly... - Insect sting allergy and venom immunotherapyDavid B K Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland 21224, USA
Ann Allergy Asthma Immunol 96:S16-21. 2006..To review specific aspects of venom immunotherapy (VIT) in the context of allergen immunotherapy (AIT) in general... - Insect sting allergy and venom immunotherapy: a model and a mysteryDavid B K Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21224, USA
J Allergy Clin Immunol 115:439-47; quiz 448. 2005..Some patients have a higher risk of relapse and should continue treatment for an extended period... - Outcomes of allergy to insect stings in children, with and without venom immunotherapyDavid B K Golden
Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21224, USA
N Engl J Med 351:668-74. 2004..We studied the outcome of allergic reactions to insect stings in childhood 10 to 20 years afterward in patients who had not received venom immunotherapy and in those who had been treated... - Pearls and pitfalls of allergy diagnostic testing: report from the American College of Allergy, Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specific IgE Test Task ForceLinda Cox
Department of Medicine, Nova Southeaster University Osteopathic College of Medicine, Davie, Florida 33334, USA
Ann Allergy Asthma Immunol 101:580-92. 2008.... - Stinging insect allergyDavid B K Golden
Johns Hopkins University School of Medicine, Asthma and Allergy Center, Baltimore, Maryland 21224, USA
Am Fam Physician 67:2541-6. 2003..Venom immunotherapy is administered every four to eight weeks for at least five years. Immunotherapy may be needed indefinitely in patients at higher risk for recurrence of anaphylaxis after treatment is stopped... - Expression of activation markers on basophils in a controlled model of anaphylaxisLaura M Gober
Department of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
J Allergy Clin Immunol 119:1181-8. 2007..Expression of activation markers on basophils has been useful in assessing sensitization in IgE-mediated diseases but has not been examined in vivo in anaphylaxis... - Increased expression of osteopontin is associated with long-term bee venom immunotherapySatoshi Konno
Johns Hopkins Asthma and Allergy Center, Baltimore, MD 21224, USA
J Allergy Clin Immunol 115:1063-7. 2005..001). CONCLUSION: The upregulation of osteopontin after VIT suggests a role of osteopontin as a candidate biomarker for VIT... - Level of osteopontin is increased after bee venom immunotherapySatoshi Konno
J Allergy Clin Immunol 115:1317-8. 2005 - Negative venom skin test results in patients with histories of systemic reaction to a stingDavid B K Golden
Insect Allergy Committee, American Academy of Allergy, Asthma and Immunology, 611 E. Wells Street, Milwaukee, WI 53202, USA
J Allergy Clin Immunol 112:495-8. 2003..We reviewed the current status of what is known about the management of individuals with a history of insect allergy but negative venom skin test results and suggested modifications of current working guidelines... - Allergy diagnostic testing: an updated practice parameterI Leonard Bernstein
University of Cincinnati College of Medicine, Ohio, USA
Ann Allergy Asthma Immunol 100:S1-148. 2008 - Risk assessment in anaphylaxis: current and future approachesF Estelle R Simons
Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada, and Department of Respiratory Medicine, Brighton General Hospital, Belfast, UK
J Allergy Clin Immunol 120:S2-24. 2007.... - Stinging insect hypersensitivity: a practice parameter updateJohn E Moffitt
Joint Council of Allergy, Asthma and Immunology, 50 N Brockway St, 3-3, Palatine, IL 60067, USA
J Allergy Clin Immunol 114:869-86. 2004 - Development and validation of a health-related quality-of-life questionnaire in patients with yellow jacket allergyJoanne N G Oude Elberink
Department of Allergology, University Hospital Groningen, The Netherlands
J Allergy Clin Immunol 109:162-70. 2002..It has been possible to develop and validate a questionnaire (the Vespid Allergy Quality of Life Questionnaire) by which the HRQL of these patients can be measured. The instrument may be administered rapidly and is easy to use...
Research Grants
- IN VITRO APPROACH TO PROBLEMS OF CLINICAL ALLERGYDavid Golden; Fiscal Year: 2005..We need to continue to study these patients to develop the most useful clinical guidelines. ..