Research Topics
| M L GillisonSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Publications
Human papillomavirus-related diseases: oropharynx cancers and potential implications for adolescent HPV vaccinationMaura L Gillison
The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
J Adolesc Health 43:S52-60. 2008..These findings have created new potential opportunities for the primary prevention of oral cancers...
Current topics in the epidemiology of oral cavity and oropharyngeal cancersMaura L Gillison
Division of Viral Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, USA
Head Neck 29:779-92. 2007..Special emphasis is placed on evaluating possible risk differences in individuals above and below the age of 45 and in users and nonusers of alcohol and tobacco...- Human retinoblastoma is not caused by known pRb-inactivating human DNA tumor virusesMaura L Gillison
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA
Int J Cancer 120:1482-90. 2007..In contrast to recent reports, we obtained substantial quantitative evidence indicating that neither HPV nor any other pRb-inactivating human DNA tumor viruses play a role in the development of retinoblastoma, regardless of RB1 genotype... 
Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancersMaura L Gillison
Division of Viral Oncology, The Johns Hopkins Kimmel Comprehensive Cancer Center, Baltimore, MD 21231, USA
J Natl Cancer Inst 100:407-20. 2008..We examined whether the risk factors for HPV-16-positive HNSCCs are similar to those for HPV-16-negative HNSCCs in a hospital-based case-control study...- HPV prophylactic vaccines and the potential prevention of noncervical cancers in both men and womenMaura L Gillison
Division of Viral Oncology, Johns Hopkins, Kimmel Cancer Center, Baltimore, Maryland 21231, USA
Cancer 113:3036-46. 2008.... - A causal role for human papillomavirus in head and neck cancerM L Gillison
Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
Lancet 363:1488-9. 2004 - Case-control study of human papillomavirus and oropharyngeal cancerAimee R Kreimer
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA
N Engl J Med 356:1944-56. 2007..Substantial molecular evidence suggests a role for human papillomavirus (HPV) in the pathogenesis of oropharyngeal squamous-cell carcinoma, but epidemiologic data have been inconsistent... - Gender differences in sexual biomarkers and behaviors associated with human papillomavirus-16, -18, and -33 seroprevalenceAimee R Kreimer
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Sex Transm Dis 31:247-56. 2004..CONCLUSION: HPV seropositivity is associated with sexually transmitted diseases among women and possibly mucosal HPV exposures in men. Tonsillar HPV infection could impact seroprevalence, particularly in men... - Oral human papillomavirus infection in adults is associated with sexual behavior and HIV serostatusAimee R Kreimer
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21231, USA
J Infect Dis 189:686-98. 2004..8; 95% confidence interval, 3.1-52.7) among HIV-seropositive individuals. HPV type 16, which is present in most HPV-associated tonsillar cancers, was the most prevalent high-risk oral HPV infection... - Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trialCarole Fakhry
Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA
J Natl Cancer Inst 100:261-9. 2008.... - Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavityPatrick K Ha
Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
Clin Cancer Res 8:1203-9. 2002..Furthermore, quantitative PCR is a useful technique that reliably excludes contaminated samples and those with minimal HPV DNA content that is unlikely to be significant in carcinogenesis... - Human papillomavirus-associated head and neck squamous cell carcinoma: mounting evidence for an etiologic role for human papillomavirus in a subset of head and neck cancersM L Gillison
The Johns Hopkins School of Hygiene and Public Health and The Johns Hopkins Comprehensive Cancer Center, Baltimore, Maryland, USA
Curr Opin Oncol 13:183-8. 2001..Bradford Hill. Data examining the association of HPV with pathogenesis of head and neck squamous cell carcinoma before 1999 were previously reviewed in this journal... - Clinical implications of human papillomavirus in head and neck cancersCarole Fakhry
Department of Viral Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, USA
J Clin Oncol 24:2606-11. 2006..The HPV etiology of these tumors may have future clinical implications for the diagnosis, therapy, screening, and prevention of HNSCC... - Delayed diagnosis and elevated mortality in an urban population with HIV and lung cancer: implications for patient careMalcolm V Brock
Johns Hopkins Hospital, and Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21287, USA
J Acquir Immune Defic Syndr 43:47-55. 2006..Lung cancer is more common in HIV-infected patients than in the general population. We examined how effectively lung cancer was being diagnosed in our HIV-infected patients... - Oral human papillomavirus infection before and after treatment for human papillomavirus 16-positive and human papillomavirus 16-negative head and neck squamous cell carcinomaYuri Agrawal
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, Maryland 21231, USA
Clin Cancer Res 14:7143-50. 2008..The prevalence of oral HPV infection before and after cancer therapy was investigated among patients with HPV16-positive and HPV16-negative HNSCC... - Development of HPV vaccines for HPV-associated head and neck squamous cell carcinomaKalpana Devaraj
Department of Pathology, The Johns Hopkins Medical Institutions, 720 Rutland Avenue, Ross Building 512, Baltimore, MD 21205, USA
Crit Rev Oral Biol Med 14:345-62. 2003..Should they fulfill their promise, these vaccines may prevent HPV infection or control its potentially life-threatening consequences in humans... - Oral sexual behaviors associated with prevalent oral human papillomavirus infectionGypsyamber D'Souza
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
J Infect Dis 199:1263-9. 2009..046, for trend) or open-mouthed kissing partners (P = .023, for trend) but not vaginal sex partners. Oral sex and open-mouthed kissing are associated with the development of oral HPV infection... - Detection of human papillomavirus-16 in fine-needle aspirates to determine tumor origin in patients with metastatic squamous cell carcinoma of the head and neckShahnaz Begum
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21231 2410, USA
Clin Cancer Res 13:1186-91. 2007..HPV16 detection thus provides a strategy for localizing an important subset of HNSCCs, but this approach has not been applied to fine-needle aspiration specimens... - Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entityMaura L Gillison
Department of Medical Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins School of Medicine, Bunting-Blaustein Cancer Research Building, 1650 Orleans Street, Baltimore, MD 21231, USA
Semin Oncol 31:744-54. 2004..It is time for clinician scientists to translate knowledge of this newly recognized disease entity into potential applications for the prevention, detection, and treatment of HPV-HNSCC... - Six-month natural history of oral versus cervical human papillomavirus infectionCarole Fakhry
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21231, USA
Int J Cancer 121:143-50. 2007..001). Our study not only demonstrates that it is feasible to study the natural history of oral HPV infection with oral rinse sampling, but also indicates that oral and cervical HPV natural history may differ... - Detection of human papillomavirus in cervical lymph nodes: a highly effective strategy for localizing site of tumor originShahnaz Begum
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Clin Cancer Res 9:6469-75. 2003..001; Fisher's exact). CONCLUSIONS: For patients with metastatic HNSCC, detection of HPV-16 is a reliable way to establish origin from the oropharynx, either directly by ISH or indirectly by immunohistochemistry for p16 overexpression... - Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United StatesAnil K Chaturvedi
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
J Clin Oncol 26:612-9. 2008.... - A new link between Fanconi anemia and human papillomavirus-associated malignanciesDouglas R Lowy
J Natl Cancer Inst 95:1648-50. 2003 - Human papillomavirus and prognosis of oropharyngeal squamous cell carcinoma: implications for clinical research in head and neck cancersMaura L Gillison
J Clin Oncol 24:5623-5. 2006 - Chapter 16: HPV vaccines in immunocompromised women and menJoel M Palefsky
Department of Medicine, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0126, USA
Vaccine 24:S3/140-6. 2006..Clinical studies are needed to determine HPV vaccine safety and effectiveness in different populations of immunocompromised women and men...
Research Grants
- A Therapeutic Vaccine for HPV 16-Positive Head and Neck CancerMaura Gillison; Fiscal Year: 2007..This application is written to request financial support for the clinical trial, including research nurse support, data management support, clinical trails compliance and auditing services, and clinical specimen processing and storage. ..