K G Ghanem

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Management of adult syphilis
    Khalil G Ghanem
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Clin Infect Dis 53:S110-28. 2011
  2. ncbi Antiretroviral therapy is associated with reduced serologic failure rates for syphilis among HIV-infected patients
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Clin Infect Dis 47:258-65. 2008
  3. ncbi Serological response to syphilis treatment in HIV-positive and HIV-negative patients attending sexually transmitted diseases clinics
    K G Ghanem
    Division of Infectious Diseases, Bayview Medical Center, Johns Hopkins University, B3 North, 4940 Eastern Avenue, Baltimore, MD 21224, USA
    Sex Transm Infect 83:97-101. 2007
  4. ncbi Lumbar puncture in HIV-infected patients with syphilis and no neurologic symptoms
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Clin Infect Dis 48:816-21. 2009
  5. ncbi REVIEW: Neurosyphilis: A historical perspective and review
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    CNS Neurosci Ther 16:e157-68. 2010
  6. ncbi Doxycycline compared with benzathine penicillin for the treatment of early syphilis
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Clin Infect Dis 42:e45-9. 2006
  7. ncbi Effect of specimen order on Chlamydia trachomatis and Neisseria gonorrhoeae test performance and adequacy of Papanicolaou smear
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Bayview Medical Center, 4940 Eastern Avenue B3 North, Baltimore, MD 21224, USA
    J Pediatr Adolesc Gynecol 19:23-30. 2006
  8. ncbi Evaluation and Management of Syphilis in the HIV-Infected Patient
    Khalil G Ghanem
    Infectious Diseases Division, Johns Hopkins University Bayview Medical Center, 4940 Eastern Avenue, B3N, Suite 352, Baltimore, MD, 21224, USA
    Curr Infect Dis Rep 12:140-6. 2010
  9. ncbi Cervical specimen order and performance measures of Chlamydia trachomatis diagnostic testing
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, B3 North, Baltimore, MD 21224, USA
    J Clin Microbiol 43:5295-7. 2005
  10. ncbi Audio computer assisted self interview and face to face interview modes in assessing response bias among STD clinic patients
    K G Ghanem
    Johns Hopkins University School of Medicine, Bayview Medical Center, Division of Infectious Diseases, Baltimore, MD 21224, USA
    Sex Transm Infect 81:421-5. 2005

Research Grants

  1. STDs, Cytokines, and Hormonal Contraception
    KHALIL GHANEM; Fiscal Year: 2007

Detail Information

Publications32

  1. ncbi Management of adult syphilis
    Khalil G Ghanem
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Clin Infect Dis 53:S110-28. 2011
    ..Several important questions regarding the management of syphilis remain unanswered and should be a priority for future research...
  2. ncbi Antiretroviral therapy is associated with reduced serologic failure rates for syphilis among HIV-infected patients
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Clin Infect Dis 47:258-65. 2008
    ..Our goal was to determine whether the degree of HIV-mediated immunosuppression and the use of highly active antiretroviral therapy impact syphilis serologic responses...
  3. ncbi Serological response to syphilis treatment in HIV-positive and HIV-negative patients attending sexually transmitted diseases clinics
    K G Ghanem
    Division of Infectious Diseases, Bayview Medical Center, Johns Hopkins University, B3 North, 4940 Eastern Avenue, Baltimore, MD 21224, USA
    Sex Transm Infect 83:97-101. 2007
    ..HIV-positive patients treated for syphilis may be at increased risk for serological failure...
  4. ncbi Lumbar puncture in HIV-infected patients with syphilis and no neurologic symptoms
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Clin Infect Dis 48:816-21. 2009
    ..The Centers for Disease Control and Prevention recommend certain criteria that warrant lumbar puncture. Here, we assess the performance of these criteria for detecting asymptomatic neurosyphilis (ANS)...
  5. ncbi REVIEW: Neurosyphilis: A historical perspective and review
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    CNS Neurosci Ther 16:e157-68. 2010
    ..Regrettably, rather than become an infection of historical significance, syphilis in the era of HIV continues to challenge researchers and clinicians...
  6. ncbi Doxycycline compared with benzathine penicillin for the treatment of early syphilis
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Clin Infect Dis 42:e45-9. 2006
    ..We compared the serological responses of patients with early syphilis treated with doxycycline with the responses of patients treated with benzathine penicillin G (BPG)...
  7. ncbi Effect of specimen order on Chlamydia trachomatis and Neisseria gonorrhoeae test performance and adequacy of Papanicolaou smear
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Bayview Medical Center, 4940 Eastern Avenue B3 North, Baltimore, MD 21224, USA
    J Pediatr Adolesc Gynecol 19:23-30. 2006
    ..To evaluate the effect of specimen collection order on the performance of diagnostic tests for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC), and the specimen adequacy of ThinPrep Papanicolaou (Pap) smears...
  8. ncbi Evaluation and Management of Syphilis in the HIV-Infected Patient
    Khalil G Ghanem
    Infectious Diseases Division, Johns Hopkins University Bayview Medical Center, 4940 Eastern Avenue, B3N, Suite 352, Baltimore, MD, 21224, USA
    Curr Infect Dis Rep 12:140-6. 2010
    ....
  9. ncbi Cervical specimen order and performance measures of Chlamydia trachomatis diagnostic testing
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, B3 North, Baltimore, MD 21224, USA
    J Clin Microbiol 43:5295-7. 2005
    ..Specimen collection order did not appear to affect the diagnostic accuracy of these tests...
  10. ncbi Audio computer assisted self interview and face to face interview modes in assessing response bias among STD clinic patients
    K G Ghanem
    Johns Hopkins University School of Medicine, Bayview Medical Center, Division of Infectious Diseases, Baltimore, MD 21224, USA
    Sex Transm Infect 81:421-5. 2005
    ..The aim of this study was to describe the difference in reporting risk behaviour in ACASI compared to a face to face interview (FFI) among public sexually transmitted diseases (STD) clinic attendees...
  11. ncbi Fluoroquinolone-resistant Neisseria gonorrhoeae: the inevitable epidemic
    Khalil G Ghanem
    Division of Infectious Diseases, Johns Hopkins University, Bayview Medical Center, 4940 Eastern Avenue, B3 North, Suite 352, Baltimore, MD 21224, USA
    Infect Dis Clin North Am 19:351-65. 2005
    ..The loss of fluoroquinolones limits available oral regimens to a single CDC-recommended antibiotic, cefixime. Oral, inexpensive, single-dose alternatives are needed to ensure continued therapeutic success...
  12. ncbi Influence of sex hormones, HIV status, and concomitant sexually transmitted infection on cervicovaginal inflammation
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    J Infect Dis 191:358-66. 2005
    ..Progesterone-based contraceptives, younger age, and race have an independent effect on cervicovaginal inflammatory cells...
  13. ncbi The association of current hormonal contraceptive use with type-specific HPV detection
    Khalil G Ghanem
    JHUBMC, ID Division, 4940 Eastern Ave, B3N Suite 352, Baltimore, MD 21224, USA
    Sex Transm Infect 87:385-8. 2011
    ..Increased duration of hormonal contraceptive (HC) use may be positively associated with the risk of invasive cervical cancer...
  14. ncbi Neurosyphilis in a clinical cohort of HIV-1-infected patients
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    AIDS 22:1145-51. 2008
    ..To describe the risk factors, clinical presentation, and long-term follow up of patients enrolled in a clinical cohort of HIV-infected patients who were diagnosed and treated for neurosyphilis...
  15. ncbi A case control study of anovaginal distance and bacterial vaginosis
    R M Brotman
    Department of Epidemiology and Public Health and the Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Int J STD AIDS 22:231-3. 2011
    ..Among high-risk women with multiple co-infections, there was no association between anovaginal distance and clinical diagnosis of BV...
  16. ncbi Gonorrhoea and chlamydia testing rates of HIV-infected men: low despite guidelines
    Stephen A Berry
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21287 2100, USA
    Sex Transm Infect 86:481-4. 2010
    ..This study determined GC/CT testing rates in a clinical HIV cohort before and after 2003 when the US Centers for Disease Control and Prevention issued guidelines for GC/CT screening...
  17. ncbi Predictors and perception of pain in women undergoing first trimester surgical abortion
    Rameet H Singh
    Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    Contraception 78:155-61. 2008
    ....
  18. ncbi The effects of illicit drug use and HIV infection on sex hormone levels in women
    Joseph Cofrancesco
    Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 0941, USA
    Gynecol Endocrinol 22:244-51. 2006
    ..001). Alcohol and crack cocaine use was not associated with sex hormone levels. Age, race, body mass index and degree of HIV immunosuppression were also associated with differences in sex hormone levels...
  19. ncbi Role of liver biopsy in management of chronic hepatitis C: a systematic review
    Kelly A Gebo
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Hepatology 36:S161-72. 2002
    ....
  20. ncbi The role of speculum and bimanual examinations when evaluating attendees at a sexually transmitted diseases clinic
    Rameet H Singh
    Divisions of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224
    Sex Transm Infect 83:206-10. 2007
    ..With the advent of molecular techniques, self-collected specimens without a clinician's examination are often adequate to detect common genital infections...
  21. ncbi Screening tests for hepatocellular carcinoma in patients with chronic hepatitis C: a systematic review
    Kelly A Gebo
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Hepatology 36:S84-92. 2002
    ..In conclusion, screening of patients with chronic hepatitis C with AFP and ultrasound may improve detection of HCC, but studies are needed to determine whether screening improves clinical outcomes...
  22. ncbi Detection and quantification of Y-chromosomal sequences by real-time PCR using the LightCycler system
    Johan H Melendez
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Sex Transm Dis 34:617-9. 2007
  23. ncbi Condom use and vaginal Y-chromosome detection: the specificity of a potential biomarker
    Khalil G Ghanem
    Division of Infectious Diseases, Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Sex Transm Dis 34:620-3. 2007
    ..Detection of vaginal Y-chromosome sequences (YCS) may be a useful biomarker to validate sexual behavior reporting in women. We describe the effects of condom use on the detection of vaginal YCS...
  24. ncbi Sexually transmitted diseases and risk behaviors among pregnant women attending inner city public sexually transmitted diseases clinics in Baltimore, MD, 1996-2002
    Hope L Johnson
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room E8537, Baltimore, MD 21205, USA
    Sex Transm Dis 34:991-4. 2007
    ..To determine the prevalence of sexually transmitted diseases (STDs) and characterize behavioral correlates among pregnant women attending inner city public STD clinics...
  25. ncbi Treatment of syphilis in HIV-infected subjects: a systematic review of the literature
    Leah J Blank
    Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA
    Sex Transm Infect 87:9-16. 2011
    ..The optimal antimicrobial regimen to treat syphilis in HIV-infected subjects remains controversial...
  26. ncbi The effect of vaginal douching cessation on bacterial vaginosis: a pilot study
    Rebecca M Brotman
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Obstet Gynecol 198:628.e1-7. 2008
    ..The objective of the study was to evaluate the risk for bacterial vaginosis (BV) in a douching cessation trial...
  27. ncbi Increases in oral and anal sexual exposure among youth attending sexually transmitted diseases clinics in Baltimore, Maryland
    Renee M Gindi
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21231, USA
    J Adolesc Health 42:307-8. 2008
    ..Odds of reporting oral sex were approximately three times higher in 2004 than in 1994; odds of anal sex were twice as high. Providers should be aware of increased risk behavior among young people...
  28. ncbi Sexually transmitted infections and prostatic inflammation/cell damage as measured by serum prostate specific antigen concentration
    Siobhan Sutcliffe
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    J Urol 175:1937-42. 2006
    ..Further studies are warranted to replicate study findings and determine host and infection characteristics associated with large PSA increases...
  29. ncbi Findings associated with recurrence of bacterial vaginosis among adolescents attending sexually transmitted diseases clinics
    Rebecca M Brotman
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21224, USA
    J Pediatr Adolesc Gynecol 20:225-31. 2007
    ..There are limited data on recurrent BV in adolescents. A relationship between the frequency of BV recurrence and specific risk factors might shed light on the pathophysiology of BV and lead to targeted interventions...
  30. ncbi HIV seroconversion among public sexually transmitted disease clinic patients: analysis of risks to facilitate early identification
    Supriya D Mehta
    Department of Emergency Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    J Acquir Immune Defic Syndr 42:116-22. 2006
    ..We identified risks for HIV seroconversion among public sexually transmitted disease (STD) clinic patients...
  31. ncbi Polymerase chain reaction detection of Y-chromosome sequences in vaginal fluid of women accessing a sexually transmitted disease clinic
    Rosemary A Jadack
    University of Wisconsin-Eau Claire, College of Nursing and Health Sciences, Eau Claire, Wisconsin, USA
    Sex Transm Dis 33:22-5. 2006
    ..CONCLUSION: The YcPCR assay can detect DNA in a clinical sample of women for up to two weeks. This assay may be useful as a qualitative adjunct to behavioral studies to further understanding of sexual behavior reporting in women...
  32. ncbi Equivalence between oral and intravenous antibiotics when treating serious staphylococcal infections?
    Khalil G Ghanem
    Clin Infect Dis 40:772; author reply 772-3. 2005

Research Grants2

  1. STDs, Cytokines, and Hormonal Contraception
    KHALIL GHANEM; Fiscal Year: 2007
    ..abstract_text> ..