Research Topics
| Richard T GeorgeSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Computed tomography myocardial perfusion imaging with 320-row detector computed tomography accurately detects myocardial ischemia in patients with obstructive coronary artery diseaseRichard T George
Johns Hopkins University, Department of Medicine, Division of Cardiology, 600 North Wolfe Street, 568 Carnegie Building, Baltimore, MD 21287, USA
Circ Cardiovasc Imaging 5:333-40. 2012..The primary aim of this study was to assess the accuracy of 320-row computed tomography perfusion imaging (CTP) to detect atherosclerosis causing myocardial ischemia...
Myocardial perfusion by CT versus hybrid imagingRichard T George
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe Street, 565C Carnegie Building, Baltimore, MD 21287, USA
Cardiol Clin 30:135-46. 2012..This article summarizes these combined technologies, emphasizing the merits and limitations of each technology and their clinical implications...
Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320-MDCT: the CT angiography and perfusion methods of the CORE320 multicenter multinational diagnostic studyRichard T George
Department of Medicine, Division of Cardiology, Johns Hopkins University School Medicine, 600 N Wolfe St, Carnegie Bldg 565C, Baltimore, MD 21287, USA
AJR Am J Roentgenol 197:829-37. 2011..CONCLUSION: We aim to describe the CT acquisition, reconstruction, and analysis methods of the CORE320 study...
Characterization and correction of beam-hardening artifacts during dynamic volume CT assessment of myocardial perfusionKakuya Kitagawa
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, 1042 Ross Building, Baltimore, MD 21205, USA
Radiology 256:111-8. 2010....
A method for reconstructing the arterial input function during helical CT: implications for myocardial perfusion distribution imagingRichard T George
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, 720 Rutland Ave, 1042 Ross Bldg, Baltimore, MD 21205, USA
Radiology 255:396-404. 2010....
Prospective electrocardiogram-gated delayed enhanced multidetector computed tomography accurately quantifies infarct size and reduces radiation exposureHyuk Jae Chang
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
JACC Cardiovasc Imaging 2:412-20. 2009....
Adenosine stress 64- and 256-row detector computed tomography angiography and perfusion imaging: a pilot study evaluating the transmural extent of perfusion abnormalities to predict atherosclerosis causing myocardial ischemiaRichard T George
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Circ Cardiovasc Imaging 2:174-82. 2009..The purpose of this study was to test whether adenosine stress computed tomography myocardial perfusion imaging (CTP), when added to CTA, can predict perfusion abnormalities caused by obstructive atherosclerosis...
CT for evaluation of myocardial cell therapy in heart failure: a comparison with CMR imagingKarl H Schuleri
Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA
JACC Cardiovasc Imaging 4:1284-93. 2011..The aim of this study was to use multidetector computed tomography (MDCT) to assess therapeutic effects of myocardial regenerative cell therapies...
Aligning coronary anatomy and myocardial perfusion territories: an algorithm for the CORE320 multicenter studyRodrigo J Cerci
Division of Cardiology and the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Circ Cardiovasc Imaging 5:587-95. 2012..The purpose of this article is to introduce a new left ventricular segmentation model for improved alignment of coronary arterial segments and myocardial perfusion territories, designed for the CORE320 study...
Rubidium-82 PET-CT for quantitative assessment of myocardial blood flow: validation in a canine model of coronary artery stenosisRiikka Lautamaki
Department of Radiology, Division of Nuclear Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21210, USA
Eur J Nucl Med Mol Imaging 36:576-86. 2009..The aim of this study was to reevaluate the feasibility of (82)Rb for flow quantification, using hybrid PET-CT in an animal model of coronary stenosis...
Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320 row detector computed tomography: design and implementation of the CORE320 multicenter, multinational diagnostic studyAndrea L Vavere
The Johns Hopkins University, Baltimore, Maryland 21287, USA
J Cardiovasc Comput Tomogr 5:370-81. 2011..If successful, the technology could revolutionize the management of patients with symptomatic CAD...
CT-based myocardial perfusion imaging-practical considerations: acquisition, image analysis, interpretation, and challengesVishal C Mehra
Department of Medicine, Division of Cardiology, Johns Hopkins University, 600 N Wolfe Street, Carnegie Building 565C, Baltimore, MD 21287, USA
J Cardiovasc Transl Res 4:437-48. 2011....
Multidetector computed tomography myocardial perfusion imaging during adenosine stressRichard T George
Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Am Coll Cardiol 48:153-60. 2006..8, p < 0.0001). CONCLUSIONS: Adenosine-augmented MDCT myocardial perfusion imaging provides semiquantitative measurements of myocardial perfusion during first-pass MDCT imaging in a canine model of LAD stenosis...
A stepwise approach to the visual interpretation of CT-based myocardial perfusionVishal C Mehra
Johns Hopkins University, Baltimore, MD, USA
J Cardiovasc Comput Tomogr 5:357-69. 2011..This systematic review uses already published methods from multiple clinical studies and is intended for general usage, independent of the platform used for image acquisition...
Applications of cardiac multidetector CT beyond coronary angiographyKarl H Schuleri
Department of Medicine, Division of Cardiology, Johns Hopkins University Baltimore, MD 21205, USA
Nat Rev Cardiol 6:699-710. 2009..In this Review, we discuss recent technical developments in cardiac MDCT and outline newly enabled noncoronary cardiac applications including viability assessment, myocardial perfusion and molecular imaging...
Characterization of peri-infarct zone heterogeneity by contrast-enhanced multidetector computed tomography: a comparison with magnetic resonance imagingKarl H Schuleri
Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, Maryland 21205, USA
J Am Coll Cardiol 53:1699-707. 2009..This study examined whether multidetector computed tomography (MDCT) improves the ability to define peri-infarct zone (PIZ) heterogeneity relative to magnetic resonance imaging (MRI)...
Recent developments in wide-detector cardiac computed tomographySang Il Choi
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, 720 Rutland Ave 1042 Ross Building, Baltimore, MD 21205, USA
Int J Cardiovasc Imaging 25:23-9. 2009..We will also review examples of wide detector coronary angiography imaging and discuss emerging complementary non-coronary applications that have been enabled by wide-detector MDCT imaging...
Quantification of myocardial perfusion using dynamic 64-detector computed tomographyRichard T George
Department of Medicine, Division of Cardiology, Image Guided Cardiotherapy Laboratory, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Invest Radiol 42:815-22. 2007....
Left ventricular function, myocardial perfusion and viabilityYasuyuki Kobayashi
Department of Medicine, Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Cardiol Clin 27:645-54. 2009..Recent technologic advances in MDCT technology in regards to detector coverage, and spatial and temporal resolution promise to improve the capabilities of cardiac CT in the assessment of cardiac function, perfusion, and viability...
Influence of image acquisition settings on radiation dose and image quality in coronary angiography by 320-detector volume computed tomography: the CORE320 pilot experienceKihei Yoneyama
Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Heart Int 7:e11. 2012..However, image quality in obese subjects was reduced compared to normal weight subjects, possibly due to tube voltage/current restrictions mandated by the study protocol...
Computational method for identifying and quantifying shape features of human left ventricular remodelingSiamak Ardekani
Institute for Computational Medicine, Johns Hopkins University, 3400 N Charles St, Baltimore, MD 21218, USA
Ann Biomed Eng 37:1043-54. 2009..This approach may be useful in identifying differences in the remodeling process between ICM and NICM populations and possibly in differentiating the populations...
CT perfusion: ready for prime timeMarietta S Ambrose
Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
Curr Cardiol Rep 13:57-66. 2011..In this review, we discuss the current state of CTP including available technology, its performance to date from current literature, and future challenges to this field...
Quantitative and qualitative analysis and interpretation of CT perfusion imagingCarolina Valdiviezo
Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
J Nucl Cardiol 17:1091-100. 2010..In doing so, we will describe the image data required for each analysis and discuss the advantages and disadvantages of each approach...
Imaging of pulmonary veins during catheter ablation for atrial fibrillation: the role of multi-slice computed tomographyHiroyuki Niinuma
Division of Cardiology, Department of Medicine, Johns Hopkins University, Carnegie 592, 600 N Wolfe Street, Baltimore, MD 21287, USA
Europace 10:iii14-21. 2008..MDCT also has been used for the assessment of serial changes in ablated PVs to detect and evaluate PV stenosis. The use of MDCT greatly aids the planning and complication-free execution of AF ablation...
Mitral annuloplasty ring dehiscence demonstrated by preablation cardiac computed tomographic angiography: influence on radiofrequency ablation of atrial fibrillationAlan Cheng
Division of Cardiology, Department of Medicine, School of Medicine, Johns Hopkins University, 600 N Wolfe Street, Carnegie 568, Baltimore, MD 21287, USA
J Cardiovasc Comput Tomogr 6:287-8. 2012..We describe the relevant imaging findings and the clinical implications this finding has on catheter selection and patient safety during a radiofrequency ablation procedure...
Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scarAlbert C Lardo
Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Circulation 113:394-404. 2006....
