Research Topics
| Charlotte Ann GaydosSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Detail Information
Publications
What Is the Role of Newer Molecular Tests in the Management of CAP?Charlotte A Gaydos
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, 530 Rangos Building, 800 North Wolfe Street, Baltimore, MD 21205, USA Electronic address
Infect Dis Clin North Am 27:49-69. 2013....
Can mailed swab samples be dry-shipped for the detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis by nucleic acid amplification tests?Charlotte A Gaydos
Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Diagn Microbiol Infect Dis 73:16-20. 2012..NAATs were able to detect CT, GC, and TV on dry transported swabs. Using NAATs for testing home-collected, urogenital swabs mailed in a dry state to a laboratory may be useful for outreach screening programs...- Genital herpes evaluation by quantitative TaqMan PCR: correlating single detection and quantity of HSV-2 DNA in cervicovaginal lavage fluids with cross-sectional and longitudinal clinical dataBulbulgul Aumakhan
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Virol J 7:328. 2010.... - The transhepatic endotoxin gradient is present despite liver cirrhosis and is attenuated after transjugular portosystemic shunt (TIPS)Daniel Benten
Department of Gastroenterology and Hepatology, University Hospital Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany
BMC Gastroenterol 11:107. 2011..Translocation of gut-derived bacterial products such as endotoxin is a major problem in liver cirrhosis... 
Internet-based screening for Chlamydia trachomatis to reach non-clinic populations with mailed self-administered vaginal swabsCharlotte A Gaydos
Johns Hopkins University, Baltimore, Maryland 21205, USA
Sex Transm Dis 33:451-7. 2006....- The use of focus groups to design an internet-based program for chlamydia screening with self-administered vaginal swabs: what women wantCharlotte A Gaydos
Johns Hopkins University, Baltimore, MD, USA
Sex Health 3:209-15. 2006..To ascertain the opinions, concerns and perceptions of sexually active women to guide the development of an internet-based chlamydia outreach and screening program using self-administered vaginal swabs as a first step to prevention... - Focus-on-Teens, sexual risk-reduction intervention for high-school adolescents: impact on knowledge, change of risk-behaviours, and prevalence of sexually transmitted diseasesC A Gaydos
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University, Baltimore, MD 21205, USA
Int J STD AIDS 19:704-10. 2008..2%. FOT was successfully implemented as an STDs/HIV risk-reduction intervention. Sustained improvements of knowledge about STDs/HIV/condom usage, decreases in sexual risk behaviours supported the effectiveness of this intervention... - Laboratory aspects of screening men for Chlamydia trachomatis in the new millenniumCharlotte A Gaydos
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University, Baltimore, Maryland, USA
Sex Transm Dis 35:S45-50. 2008..To describe and review the methods for laboratory diagnosis of Chlamydia trachomatis in men... - Chlamydia trachomatis reinfection rates among female adolescents seeking rescreening in school-based health centersCharlotte A Gaydos
Johns Hopkins University, Baltimore, Maryland, USA
Sex Transm Dis 35:233-7. 2008..Chlamydia trachomatis (CT) infections are common among adolescents attending high and middle schools. The study objective was to determine the reinfection rates of CT for females attending school-based health centers... - Mycoplasma genitalium compared to chlamydia, gonorrhoea and trichomonas as an aetiological agent of urethritis in men attending STD clinicsC Gaydos
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Sex Transm Infect 85:438-40. 2009..To investigate prevalence of Mycoplasma genitalium, Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis in men, frequency of co-infections, and association of organisms with urethritis in men... - Mycoplasma genitalium as a contributor to the multiple etiologies of cervicitis in women attending sexually transmitted disease clinicsCharlotte Gaydos
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Sex Transm Dis 36:598-606. 2009.... - Performance of the Abbott RealTime CT/NG for detection of Chlamydia trachomatis and Neisseria gonorrhoeaeC A Gaydos
Johns Hopkins University, 855 North Wolfe St, 530 Rangos Building, Baltimore, MD 21205, USA
J Clin Microbiol 48:3236-43. 2010..trachomatis and N. gonorrhoeae dual detection with high sensitivity and specificity. The automated assay provides a useful alternative nucleic acid amplification assay for clinical laboratories and clinicians... - Chlamydia trachomatis age-specific prevalence in women who used an internet-based self-screening program compared to women who were screened in family planning clinicsCharlotte A Gaydos
Division of Infectious Diseases, Medicine, Johns Hopkins University, Baltimore, MD, USA
Sex Transm Dis 38:74-8. 2011..To determine whether women who collect self-collected vaginal swabs at home demonstrated a higher positivity of Chlamydia trachomatis than women in family planning clinics... - Trichomonas vaginalis infection in women who submit self-obtained vaginal samples after internet recruitmentCharlotte A Gaydos
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University, Baltimore, MD, USA
Sex Transm Dis 38:828-32. 2011..Submission of self-obtained vaginal samples (SOVs) collected at home could remove barriers that women face in getting tested for sexually transmitted infections (STIs). Internet recruitment of SOVs is highly acceptable... - Impact of international laboratory partnerships on the performance of HIV/sexually transmitted infection testing in five resource-constrained countriesC A Gaydos
Division of Infectious Diseases, Johns Hopkins University, Baltimore, MD 21205, USA
Int J STD AIDS 22:645-52. 2011..Building collaborative partnership relations can establish a sustainable network for clinical trials, and can lead to accreditation and international laboratory development... - Prevalence of Neisseria Gonorrhoeae among men screened for Chlamydia Trachomatis in four United States cities, 1999-2003Charlotte Ann Gaydos
Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Sex Transm Dis 33:314-9. 2006..We describe the prevalence of gonorrhea in a large sample of men tested for gonorrhea and Chlamydia trachomatis in Baltimore, Denver, San Francisco, and Seattle... - Performance of the MagNA pure LC robot for extraction of Chlamydia trachomatis and Neisseria gonorrhoeae DNA from urine and swab specimensNicholas Dalesio
School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA
J Clin Microbiol 42:3300-2. 2004..The robot provided a highly sensitive and specific method of DNA extraction... - Nucleic acid amplification tests for gonorrhea and chlamydia: practice and applicationsCharlotte A Gaydos
Division of Infectious Diseases, Medicine, Johns Hopkins University School of Medicine, 1159 Ross Research Building, 720 Rutland Avenue, Baltimore, MD 21205, USA
Infect Dis Clin North Am 19:367-86, ix. 2005..The application of NAATs to self-collected specimens has the potential to augment public health programs designed to control the epidemic of STIs in the community... - Comparison of three nucleic acid amplification tests for detection of Chlamydia trachomatis in urine specimensCharlotte A Gaydos
Johns Hopkins University, 720 Rutland Ave, Ross 1159, Baltimore, MD 21205, USA
J Clin Microbiol 42:3041-5. 2004..We found that the LCx, ProbeTec, and AC2 NAATs are highly sensitive and specific methods for the detection of C. trachomatis in urine specimens and can be recommended for noninvasive screening of C. trachomatis in urine... - Evaluation of dry and wet transported intravaginal swabs in detection of Chlamydia trachomatis and Neisseria gonorrhoeae infections in female soldiers by PCRCharlotte A Gaydos
Johns Hopkins University School of Medicine Johns Hopkins University School of Public Health and Hygiene, Baltimore, Maryland 21205, USA
J Clin Microbiol 40:758-61. 2002..9% (24 of 27) and 98.3% (753 of 766), respectively. PCR testing of wet and dry transported intravaginal swabs to detect chlamydia and gonorrhea infections was an accurate diagnostic method for military women... - Sustained high prevalence of Chlamydia trachomatis infections in female army recruitsCharlotte A Gaydos
Infectious Disease Division, The Johns Hopkins University, Baltimore, Maryland 21205, USA
Sex Transm Dis 30:539-44. 2003..Screening and treatment of infected females has been demonstrated to prevent sequelae such as pelvic inflammatory disease... - Will patients "opt in" to perform their own rapid HIV test in the emergency department?Charlotte A Gaydos
Division of Infectious Diseases, Johns Hopkins University, Baltimore, MD 21205, USA
Ann Emerg Med 58:S74-8. 2011..We evaluate the feasibility and accuracy of existing point-of-care HIV tests performed by an untrained patient compared with the routinely used HIV point-of-care test offered to patients in 2 urban emergency departments (EDs)... - Urine nucleic acid amplification tests for the diagnosis of sexually transmitted infections in clinical practiceCharlotte A Gaydos
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Curr Opin Infect Dis 18:55-66. 2005.... - Female prisoners' preferences of collection methods for testing for Chlamydia trachomatis and Neisseria gonorrhoeae infectionSara B Newman
Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Sex Transm Dis 30:306-9. 2003..A majority of participants expressed a preference for noninvasive techniques rather than a pelvic examination... - Performance of three nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae by use of self-collected vaginal swabs obtained via an Internet-based screening programBillie Jo Masek
Johns Hopkins University, 530 Rangos Bldg, 855 North Wolfe St, Baltimore, MD 21205, USA
J Clin Microbiol 47:1663-7. 2009..5% and 80%, respectively, for ProbeTec. For 500 PCR samples, the C. trachomatis sensitivity was 100% and the N. gonorrhoeae sensitivity was 100%, with specificities of 99.3% and 98.8%, respectively... - Surveillance of Chlamydia trachomatis and Neisseria gonorrhoeae infections in women in detention in Baltimore, MarylandJustin Hardick
The Johns Hopkins University, Baltimore, Maryland 21205, USA
Sex Transm Dis 30:64-70. 2003..In conjunction with a program to expand syphilis and HIV infection services, women were also offered screening for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) during intake at the Baltimore Women's Detention Center... - Comparison of the urine Leukocyte Esterase Test to a Nucleic Acid Amplification Test for screening non-health care-seeking male soldiers for Chlamydia trachomatis and Neisseria gonorrhoeae infectionsBillie Jo Wood
Johns Hopkins University, 720 Rutland Avenue, Ross 1164, Baltimore, MD 21205, USA
Mil Med 172:770-2. 2007..In this population, the prevalence of gonorrhea was too low to produce reliable estimates of performance characteristics of the LET for gonorrhea. The LET is not warranted for use in screening non-health care-seeking male Army trainees... - Prevalence and correlates of chlamydia trachomatis, neisseria gonorrhoeae, trichomonas vaginalis infections, and bacterial vaginosis among a cohort of young injection drug users in Baltimore, MarylandSabrina S Plitt
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
Sex Transm Dis 32:446-53. 2005..5; 95% CI, 1.1-5.7). CONCLUSIONS: Despite high sexual risk, STI prevalence among young IDUs was similar to that of the general population. BV prevalence was high, suggesting that future STI assessments among female IDUs should include BV... - From the NIH: proceedings of a workshop on the importance of self-obtained vaginal specimens for detection of sexually transmitted infectionsMarcia M Hobbs
Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Sex Transm Dis 35:8-13. 2008..Similarly, SOVs should be explored for use in the diagnosis of other sexually transmitted pathogens... - Feasibility and short-term impact of linked education and urine screening interventions for Chlamydia and gonorrhea in male army recruitsChristine M Arcari
Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA
Sex Transm Dis 31:443-7. 2004..The objective of this study was to assess the feasibility of an intervention for sexually transmitted diseases (STDs) and a screening program for Chlamydia trachomatis and Neisseria gonorrhoeae infections in male Army recruits... - The microbicide tenofovir does not inhibit nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine samplesBillie Jo Wood
The Johns Hopkins University School of Medicine, Division of Infectious Diseases, Baltimore, Maryland, USA
J Clin Microbiol 46:763-5. 2008..Concentrations of 5% to 0% of tenofovir and the placebo were added to dilutions of C. trachomatis and N. gonorrhoeae. No appreciable inhibition was observed... - Quantitative multiprobe PCR assay for simultaneous detection and identification to species level of bacterial pathogensSamuel Yang
Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Clin Microbiol 40:3449-54. 2002..This assay has broad potential in the clinical arena for rapid and specific diagnosis of infectious diseases... - Perceptions of an ideal point-of-care test for sexually transmitted infections--a qualitative study of focus group discussions with medical providersYu Hsiang Hsieh
Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
PLoS ONE 5:e14144. 2010..Therefore, our objective was to explore the perceptions of the ideal types of STI POCT for use in health care settings... - Detection of bacteremia in emergency department patients at risk for infective endocarditis using universal 16S rRNA primers in a decontaminated polymerase chain reaction assayRichard E Rothman
Department of Emergency Medicine, Johns Hopkins University, Bethesda, Maryland 21205, USA
J Infect Dis 186:1677-81. 2002..This assay provides a promising diagnostic for rapid identification of bacteremia, particularly valuable in acute care settings... - Antiviral prescriptions to U.S. ambulatory care visits with a diagnosis of influenza before and after high level of adamantane resistance 2005-06 seasonYu Hsiang Hsieh
Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
PLoS ONE 5:e8945. 2010..We also determined providers' adherence to Centers for Disease Control and Prevention (CDC) 2006 interim treatment guidelines for influenza after the dissemination of guidelines... - Hospitalization rates in female US Army recruits associated with a screening program for Chlamydia trachomatisKathryn L Clark
Allied Technology Group, Rockville, Maryland, USA
Sex Transm Dis 29:1-5. 2002..The pelvic inflammatory disease hospitalization rate in women with C trachomatis who were screened and treated was similar to that observed in uninfected women... - Rapid polymerase chain reaction-based screening assay for bacterial biothreat agentsSamuel Yang
Department of Emergency Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
Acad Emerg Med 15:388-92. 2008..To design and evaluate a rapid polymerase chain reaction (PCR)-based assay for detecting Eubacteria and performing early screening for selected Class A biothreat bacterial pathogens... - Plasma antibodies against Chlamydia trachomatis, human papillomavirus, and human herpesvirus type 8 in relation to prostate cancer: a prospective studySiobhan Sutcliffe
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6132 A, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 16:1573-80. 2007..70; 95% CI, 0.52-0.95). As this study is the first, to our knowledge, to observe such an inverse association, similar additional studies are warranted... - Plasma antibodies against Trichomonas vaginalis and subsequent risk of prostate cancerSiobhan Sutcliffe
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6138, 615 North Wolfe Street, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 15:939-45. 2006..As this study is the first, to our knowledge, to investigate associations between T. vaginalis serology and prostate cancer, additional studies are necessary before conclusions can be made... - Utilising the internet to test for sexually transmitted infections: results of a survey and accuracy testingSherria L Owens
Morgan State University, School of Community Health and Policy, Baltimore, Maryland, USA
Sex Transm Infect 86:112-6. 2010..Searching the internet for information about sexually transmitted infections (STI) is common. The goal of the study was to discover which internet sites offer STI tests and obtain information about the services and their validity... - Trichomonas vaginalis polymerase chain reaction compared with standard diagnostic and therapeutic protocols for detection and treatment of vaginal trichomoniasisKaren A Wendel
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Clin Infect Dis 35:576-80. 2002..02). TV is significantly undertreated using standard algorithms for metronidazole therapy. Given the association of trichomoniasis with perinatal morbidity and HIV transmission, women in high-risk groups may benefit from TV PCR... - Temporal arteritis and Chlamydia pneumoniae: failure to detect the organism by polymerase chain reaction in ninety cases and ninety controlsMichael J Regan
Johns Hopkins University, Baltimore, Maryland, USA
Arthritis Rheum 46:1056-60. 2002..CONCLUSION: The results of this study using sensitive and specific PCR analyses do not support a role for C pneumoniae in the pathogenesis of TA... - National survey of Laboratory Response Network sentinel laboratory preparednessBrian T Kalish
Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21209, USA
Disaster Med Public Health Prep 3:S17-23. 2009..The aim of the present study was to broadly describe preparedness of the first tier of the hospital LRN, the sentinel laboratories, with a specific focus on training, personnel, and communications... - Chlamydia trachomatis-infected patients display variable antibody profiles against the nine-member polymorphic membrane protein familyChun Tan
Department of Microbial Pathogenesis, University of Maryland Dental School, Baltimore, 21201, USA
Infect Immun 77:3218-26. 2009..Overall, our results indicate that the Pmps elicit various serologic responses in C. trachomatis-infected patients and are consistent with the pmp gene family being the basis of a mechanism of antigenic variation... - Prevalence of Chlamydia trachomatis infection among men screened in 4 U.S. citiesJulia Ann Schillinger
Centers for Disease Control and Prevention CDC, Atlanta, Georgia 30033, USA
Sex Transm Dis 32:74-7. 2005..The objective of this study was to measure the prevalence of Chlamydia trachomatis (CT) infection among men in clinical and nonclinical settings across the United States...
Research Grants
- INTERVENTIONS FOR STDS IN HIGH SCHOOLSCharlotte Gaydos; Fiscal Year: 2002..This multi-disciplinary and cooperative study encompassing behavioral, interventional, epidemiological, and biological sciences will evaluate a behavioral approach to STD prevention and control. ..