J M Freeman

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. doi request reprint Rights, respect for dignity and end-of-life care: time for a change in the concept of informed consent
    J M Freeman
    J Med Ethics 36:61-2. 2010
  2. ncbi request reprint Less testing is needed in the emergency room after a first afebrile seizure
    John M Freeman
    Johns Hopkins Medical Institutions, Baltimore, MD 21247 7247, USA
    Pediatrics 111:194-6. 2003
  3. ncbi request reprint Expert medical testimony: Responsibilities of medical societies
    John M Freeman
    Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Neurology 63:1557-8. 2004
  4. pmc Ethical theory and medical ethics: a personal perspective
    J M Freeman
    Meyer 2 147, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J Med Ethics 32:617-8. 2006
  5. ncbi request reprint The ketogenic diet: one decade later
    John M Freeman
    John M Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, MD 21287 7247, USA
    Pediatrics 119:535-43. 2007
  6. ncbi request reprint The use of amplitude-integrated electroencephalography: beware of its unintended consequences
    John M Freeman
    John M Freeman Pediatric Epilepsy Center, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Pediatrics 119:615-7. 2007
  7. ncbi request reprint Beware: the misuse of technology and the law of unintended consequences
    John M Freeman
    Department of Neurology and the Berman Institute of Bioethics, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Neurotherapeutics 4:549-54. 2007
  8. doi request reprint The ketogenic diet: additional information from a crossover study
    John M Freeman
    Pediatric Epilepsy Center, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Child Neurol 24:509-12. 2009
  9. ncbi request reprint The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one year
    Elisabeth B Marsh
    John M Freeman Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, The Johns Hopkins Medical Institutions, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MS 21287 1000, U S A
    Epilepsia 47:425-30. 2006
  10. ncbi request reprint The ketogenic diet: a 3- to 6-year follow-up of 150 children enrolled prospectively
    C Hemingway
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Pediatrics 108:898-905. 2001

Collaborators

Detail Information

Publications39

  1. doi request reprint Rights, respect for dignity and end-of-life care: time for a change in the concept of informed consent
    J M Freeman
    J Med Ethics 36:61-2. 2010
    ..They may impinge on the dignity of the patient as well as subject society to unwarranted expense. In order to provide affordable healthcare for all, these concepts are in need of modification...
  2. ncbi request reprint Less testing is needed in the emergency room after a first afebrile seizure
    John M Freeman
    Johns Hopkins Medical Institutions, Baltimore, MD 21247 7247, USA
    Pediatrics 111:194-6. 2003
  3. ncbi request reprint Expert medical testimony: Responsibilities of medical societies
    John M Freeman
    Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Neurology 63:1557-8. 2004
    ..Specialty societies, such as the American Academy of Neurology, should be willing to review complaints about unsubstantiated testimony and, at times, publicly discipline offending experts...
  4. pmc Ethical theory and medical ethics: a personal perspective
    J M Freeman
    Meyer 2 147, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    J Med Ethics 32:617-8. 2006
  5. ncbi request reprint The ketogenic diet: one decade later
    John M Freeman
    John M Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, MD 21287 7247, USA
    Pediatrics 119:535-43. 2007
    ..Finally, this review looks toward possible future uses of the ketogenic diet for conditions other than epilepsy...
  6. ncbi request reprint The use of amplitude-integrated electroencephalography: beware of its unintended consequences
    John M Freeman
    John M Freeman Pediatric Epilepsy Center, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Pediatrics 119:615-7. 2007
  7. ncbi request reprint Beware: the misuse of technology and the law of unintended consequences
    John M Freeman
    Department of Neurology and the Berman Institute of Bioethics, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Neurotherapeutics 4:549-54. 2007
    ..What are the ethics of continued approval and introduction of unevaluated technology? What is the wisdom of its use? Beware of the unintended consequences...
  8. doi request reprint The ketogenic diet: additional information from a crossover study
    John M Freeman
    Pediatric Epilepsy Center, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Child Neurol 24:509-12. 2009
    ..The diet remained effective in decreasing seizures of the Lennox-Gastaut syndrome at 12 days, 6 months, and 12 months. In conclusion, the ketogenic diet is effective in decreasing the drop seizures of the Lennox-Gastaut syndrome...
  9. ncbi request reprint The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one year
    Elisabeth B Marsh
    John M Freeman Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, The Johns Hopkins Medical Institutions, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MS 21287 1000, U S A
    Epilepsia 47:425-30. 2006
    ..To determine the long-term outcome of children with difficult-to-control seizures who remained on the ketogenic diet for <1 year...
  10. ncbi request reprint The ketogenic diet: a 3- to 6-year follow-up of 150 children enrolled prospectively
    C Hemingway
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Pediatrics 108:898-905. 2001
    ..The diet often allows decrease or discontinuation of medication. It is more effective than many of the newer anticonvulsants and is well-tolerated when it is effective...
  11. ncbi request reprint The ketogenic diet: seizure control correlates better with serum beta-hydroxybutyrate than with urine ketones
    D L Gilbert
    Pediatric Epilepsy Center, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    J Child Neurol 15:787-90. 2000
    ..At present, however, urine ketones are the only readily available inexpensive approach to ketone assessment...
  12. ncbi request reprint The ketogenic diet: adolescents can do it, too
    Mackenzie A Mady
    Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Epilepsia 44:847-51. 2003
    ..To determine both the efficacy of and compliance with the ketogenic diet in the adolescent population...
  13. ncbi request reprint Risk factors for urolithiasis in children on the ketogenic diet
    S L Furth
    Division of Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD 21287 2535, USA
    Pediatr Nephrol 15:125-8. 2000
    ..In conjunction with low fluid intake, these patients are at high risk for both uric acid and calcium stone formation...
  14. ncbi request reprint The postoperative course and management of 106 hemidecortications
    E H Kossoff
    Department of Neurology and Pediatrics, The Pediatric Epilepsy Center, Johns Hopkins Medicla Institutions, Baltimore, MD, USA
    Pediatr Neurosurg 37:298-303. 2002
    ..The purpose of this study was to evaluate the short-term issues surrounding hemispherectomy and their management in a series of patients from our institution...
  15. ncbi request reprint The pathology of Rasmussen syndrome: stages of cortical involvement and neuropathological studies in 45 hemispherectomies
    Carlos A Pardo
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Epilepsia 45:516-26. 2004
    ..To characterize the profile of cortical involvement in RS, we studied the pathological changes in the cerebral cortex of 45 hemispherectomies performed at Johns Hopkins Hospital between 1985 and 2002...
  16. ncbi request reprint Experience in the use of the ketogenic diet as early therapy
    James E Rubenstein
    Department of Neurology, Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, MD 21287 1000, USA
    J Child Neurol 20:31-4. 2005
    ..6). The ketogenic diet can be a valuable therapy before epilepsy becomes intractable. In the 13 patients reported, efficacy without side effects was achieved similarly to that with patients with intractable epilepsy...
  17. ncbi request reprint Growth of children on the ketogenic diet
    Eileen P G Vining
    The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Dev Med Child Neurol 44:796-802. 2002
    ..The ketogenic diet generally provides sufficient nutrition to maintain growth within normal parameters over a defined period. Very young children grow poorly on the diet and should be followed-up carefully over long periods of use...
  18. ncbi request reprint Kidney stones, carbonic anhydrase inhibitors, and the ketogenic diet
    Eric H Kossoff
    The Pediatric Epilepsy Center, Departments of Neurology and Pediatrics, and Division of Pediatric Nephrology, Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 1000, USA
    Epilepsia 43:1168-71. 2002
    ..The objective of this study was to establish the prevalence of nephrolithiasis in children in this combination-therapy population...
  19. ncbi request reprint Outcomes of 32 hemispherectomies for Sturge-Weber syndrome worldwide
    Eric H Kossoff
    Pediatric Epilepsy Center, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Neurology 59:1735-8. 2002
    ..Epilepsy affects 80% of patients with Sturge-Weber syndrome; the majority of seizures begin before the age of 1. When seizures are intractable to medications and unihemispheric, hemispherectomy is often advised...
  20. ncbi request reprint Efficacy of the ketogenic diet for infantile spasms
    Eric H Kossoff
    Department of Neurology, Pediatric Epilepsy Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Pediatrics 109:780-3. 2002
    ..The objective of this study was to determine whether the ketogenic diet is safe, well-tolerated, and efficacious in the treatment of infantile spasms...
  21. ncbi request reprint Efficacy of the Atkins diet as therapy for intractable epilepsy
    Eric H Kossoff
    Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287 1000, USA
    Neurology 61:1789-91. 2003
    ..This provides preliminary evidence that the Atkins diet may have a role as therapy for patients with medically resistant epilepsy...
  22. doi request reprint A case-control evaluation of the ketogenic diet versus ACTH for new-onset infantile spasms
    Eric H Kossoff
    Department of Neurology, John M Freeman Pediatric Epilepsy Center, Johns Hopkins Medical Institutes, Baltimore, Maryland 21287 1000, USA
    Epilepsia 49:1504-9. 2008
    ..We hypothesized the ketogenic diet (KD), previously reported as beneficial for intractable infantile spasms, would have similar efficacy, but better tolerability than ACTH when used first-line...
  23. ncbi request reprint Landau-Kleffner syndrome responsive to levetiracetam
    Eric H Kossoff
    Department of Neurology, The Johns Hopkins Hospital, Jefferson 128, 600 North Wolfe Street, Baltimore, MD 21287 1000, USA
    Epilepsy Behav 4:571-5. 2003
    ..Levetiracetam should be considered as therapy for Landau-Kleffner syndrome...
  24. ncbi request reprint Effect of a high-fat ketogenic diet on plasma levels of lipids, lipoproteins, and apolipoproteins in children
    Peter O Kwiterovich
    Lipid Research Atherosclerosis Division, Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    JAMA 290:912-20. 2003
    ..Little prospective long-term information is available on the effect of a ketogenic diet on plasma lipoproteins in children with difficult-to-control seizures...
  25. ncbi request reprint Tuberous sclerosis complex and the ketogenic diet
    Eric H Kossoff
    Departments of Neurology and Pediatrics, The John M Freeman Pediatric Epilepsy Center, Johns Hopkins University, Baltimore, MD 212871000, USA
    Epilepsia 46:1684-6. 2005
    ..If medications fail and no clear epileptogenic tuber is identified, nonpharmacologic therapies are often attempted. The use of the ketogenic diet specifically for children with TSC and epilepsy has not been previously described...
  26. ncbi request reprint The importance of parental expectations of cognitive improvement for their children with epilepsy prior to starting the ketogenic diet
    Sharifeh Farasat
    Department of Pediatrics, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Epilepsy Behav 8:406-10. 2006
    ..001) and >90% seizure reduction (P=0.04) at 6 months positively correlated with longer eventual diet duration. Expectations for cognitive improvement need to be discussed prior to beginning the ketogenic diet...
  27. doi request reprint A blinded, crossover study of the efficacy of the ketogenic diet
    John M Freeman
    Departments of Neurology and Pediatrics, The John M Freeman Pediatric Epilepsy Center, Baltimore, Maryland, USA
    Epilepsia 50:322-5. 2009
    ..5 seizures per day (p = 0.07). There was no reduction in the number of EEG-identified events, with a median reduction of 7 events per day (p = 0.33). Ketosis was not completely eliminated in the glucose-added arm...
  28. ncbi request reprint Hemispherectomy for intractable unihemispheric epilepsy etiology vs outcome
    E H Kossoff
    Department of Neurology, The Pediatric Epilepsy Center, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Neurology 61:887-90. 2003
    ..A prior case series focused on the outcomes after 58 surgeries at Johns Hopkins Hospital in 1997. This series, and an additional 53 cases, were reviewed to bring the outcomes up to date...
  29. ncbi request reprint Effects of ketogenic diet on development and behavior: preliminary report of a prospective study
    M B Pulsifer
    Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 7218, USA
    Dev Med Child Neurol 43:301-6. 2001
    ..These preliminary results support prior anecdotal reports of the beneficial effects of the diet on cognition and behavior...
  30. ncbi request reprint Levetiracetam psychosis in children with epilepsy
    E H Kossoff
    Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 7247, USA
    Epilepsia 42:1611-3. 2001
    ..Observations in children are limited; levetiracetam is not yet approved by the Food and Drug Administration for use in children...
  31. ncbi request reprint Energy requirements of spasticity
    C Hemingway
    Department of Neurology, Johns Hopkins Medical Institutions, Baltimore 21287-7247, USA
    Dev Med Child Neurol 43:277-8. 2001
    ..It was concluded that when calculation of calories is critical, energy utilization by spasticity must be taken into consideration...
  32. doi request reprint Hemispherectomy sustained before adulthood does not cause persistent hemispatial neglect
    Elisabeth B Marsh
    Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cortex 45:677-85. 2009
    ....
  33. ncbi request reprint Rasmussen's syndrome: progressive autoimmune multi-focal encephalopathy
    John M Freeman
    Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 7247, USA
    Pediatr Neurol 32:295-9. 2005
    ..Hemispherectomy of one form or another is the only curative therapy, and there is no evidence that one form of hemispherectomy is preferable to another. Immuno-ablative therapy may be a therapy of the future...
  34. ncbi request reprint EEG is an essential clinical tool: pro and con
    Nathan B Fountain
    Comprehensive Epilepsy Program, University of Virginia, Charlottesville, Virginia 22908, USA
    Epilepsia 47:23-5. 2006
    ..Both authors agree that the EEG should only be ordered with forethought to answer a specific question...
  35. ncbi request reprint Benefits of an all-liquid ketogenic diet
    Eric H Kossoff
    Epilepsia 45:1163. 2004
  36. ncbi request reprint The cognitive outcome of hemispherectomy in 71 children
    Margaret B Pulsifer
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114 2696, USA
    Epilepsia 45:243-54. 2004
    ..Seizures were due to cortical dysplasias (n = 27), Rasmussen syndrome (n = 37), or vascular malformations or strokes (n = 7). Both presurgical and follow-up results are available and reported for 53 patients...
  37. ncbi request reprint A progressive anterior fibrosis syndrome in patients with postsurgical congenital aniridia
    Julie H Tsai
    University of Cincinnati and Cincinnati Eye Institute, Cincinnati, Ohio, USA
    Am J Ophthalmol 140:1075-9. 2005
    ..To report the characteristics of a newly recognized clinical entity in congenital aniridia that we have termed aniridic fibrosis syndrome...
  38. ncbi request reprint On learning humility: a thirty-year journey
    John M Freeman
    Johns Hopkins University School of Medicine, USA
    Hastings Cent Rep 34:13-6. 2004
  39. ncbi request reprint Chorioamnionitis, cytokines, and brain injury
    John M Freeman
    Pediatrics 112:206-7; author reply 206-7. 2003