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Species | Stephen J FreedlandSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Predictors of prostate-specific antigen progression among men with seminal vesicle invasion at the time of radical prostatectomyStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Cancer 100:1633-8. 2004..The authors examined whether there was a subset of men with SV invasion who had long-term prostate-specific antigen (PSA) progression-free survival...- Obesity does not adversely affect health-related quality-of-life outcomes after anatomic retropubic radical prostatectomyStephen J Freedland
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 2101, USA
Urology 65:1131-6. 2005..To study the impact of obesity on the health-related quality-of-life (HRQOL) outcomes after radical prostatectomy (RP)... - Stronger association between obesity and biochemical progression after radical prostatectomy among men treated in the last 10 yearsStephen J Freedland
Departments of Urology, and Pathology, The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Clin Cancer Res 11:2883-8. 2005..Whether the association between obesity and aggressive disease has changed as a result of these temporal changes is unclear... - Obesity and prostate cancerStephen J Freedland
Brady Urological Institute, Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287-2101, USA
Urology 65:433-9. 2005 - Serum leptin and pathological findings at the time of radical prostatectomyStephen J Freedland
James Buchanan Brady Urological Institute and the Department of Urology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Urol 173:773-6. 2005..Obese men have higher serum leptin, a hormone produced by adipocytes, which has also been shown to be an in vitro prostate cancer growth factor. We examined whether serum leptin correlates with advanced pathological findings at RP... - Explaining racial differences in prostate cancer in the United States: sociology or biology?Stephen J Freedland
The Brady Urological Institute, Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2101, USA
Prostate 62:243-52. 2005..Finally, we conclude with some thoughts as to how to integrate the findings from sociological as well as biological studies and touch upon methods to reduce the disparate burden of prostate cancer among blacks in the United States... - Prostate cancer--Fourth International CongressStephen J Freedland
Johns Hopkins Hospital, Brady Urological Institute, Marburg 130, 600 N Wolfe Street, Baltimore, MD 21287-2101, USA
IDrugs 7:717-20. 2004 - Impact of obesity on biochemical control after radical prostatectomy for clinically localized prostate cancer: a report by the Shared Equal Access Regional Cancer Hospital database study groupStephen J Freedland
Department of Urology, The Johns Hopkins School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287 2101, USA
J Clin Oncol 22:446-53. 2004..Given the limited information regarding the impact of obesity on treatment outcomes for prostate cancer, we sought to examine the relationship between body mass index (BMI) and cancer control after radical prostatectomy (RP)... - Obesity and biochemical outcome following radical prostatectomy for organ confined disease with negative surgical marginsStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287 2101, USA
J Urol 172:520-4. 2004.... - Body mass index as a predictor of prostate cancer: development versus detection on biopsyStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2101, USA
Urology 66:108-13. 2005..To determine whether obesity is biologically associated with an increased risk of prostate cancer development, especially aggressive disease and to explore whether a bias may exist in our ability to detect these cancers in obese patients... - Obesity and capsular incision at the time of open retropubic radical prostatectomyStephen J Freedland
The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland 21287 2101, USA
J Urol 174:1798-801; discussion 1801. 2005..Therefore, we examined the association between body mass index (BMI) and capsular incision at RP as a surrogate of a poor technical operation in men treated for prostate cancer by several high volume surgeons at a center of excellence... - Risk of prostate cancer-specific mortality following biochemical recurrence after radical prostatectomyStephen J Freedland
The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
JAMA 294:433-9. 2005.... - Are findings from studies of obesity and prostate cancer really in conflict?Stephen J Freedland
James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Cancer Causes Control 17:5-9. 2006..Finally, additional methodological issues are discussed that investigators need to be aware of to be able to draw inferences across studies of obesity and prostate cancer outcomes... - Racial differences in prognostic value of adult height for biochemical progression following radical prostatectomyStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Clin Cancer Res 11:7735-42. 2005..However, hormonal activity and diets vary between races. We examined whether height was significantly associated with biochemical progression following radical prostatectomy and whether there was an interaction between height and race... - Prostate size and risk of high-grade, advanced prostate cancer and biochemical progression after radical prostatectomy: a search database studyStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, 600 N Wolfe St, Baltimore, MD 21287 2101, USA
J Clin Oncol 23:7546-54. 2005..We examined whether prostate weight was associated with tumor grade, advanced disease, or risk of biochemical progression after radical prostatectomy (RP)... - Biochemical failure after radical prostatectomy in men with pathologic organ-confined disease: pT2a versus pT2bStephen J Freedland
Department of Urology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Cancer 100:1646-9. 2004..Whether this distinction provides prognostic significance is unclear. The authors evaluated biochemical outcomes between men with pT2aN0 and pT2bN0 disease... - Obesity and prostate cancer: a growing problemStephen J Freedland
Jmaes Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287-2101, USA
Clin Cancer Res 11:6763-6. 2005 - The prostatic specific antigen era is alive and well: prostatic specific antigen and biochemical progression following radical prostatectomyStephen J Freedland
The James Buchanan Brady Urological Institute, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2101, USA
J Urol 174:1276-81; discussion 1281; author reply 1281. 2005..We examined the association between PSA and clinical progression in men undergoing RP... - Association between serum adiponectin, and pathological stage and grade in men undergoing radical prostatectomyStephen J Freedland
The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287 2101, USA
J Urol 174:1266-70. 2005..Obesity has been associated with advanced stage and a higher risk of biochemical progression following radical prostatectomy (RP) in several series. We examined whether serum adiponectin is associated with advanced disease stage at RP... - Obesity and risk of biochemical progression following radical prostatectomy at a tertiary care referral centerStephen J Freedland
Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2101, USA
J Urol 174:919-22. 2005..We sought to validate or refute these findings using data on men treated by multiple other surgeons at our institution... - Comparison of percentage of total prostate needle biopsy tissue with cancer to percentage of cores with cancer for predicting PSA recurrence after radical prostatectomy: results from the SEARCH databaseStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, 90095-1738, USA
Urology 61:742-7. 2003.... - Improved clinical staging system combining biopsy laterality and TNM stage for men with T1c and T2 prostate cancer: results from the SEARCH databaseStephen J Freedland
Department of Urology, University of California-Los Angeles School of Medicine and Department of Surgery, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California 90095, USA
J Urol 169:2129-35. 2003..If confirmed at other centers and in men who undergo with other treatment modalities, consideration should be given to revising the current TNM staging system to reflect these findings... - Time trends in biochemical recurrence after radical prostatectomy: results of the SEARCH databaseStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, 90095-1738, USA
Urology 61:736-41. 2003..This may reflect lead-time bias in detecting PSA recurrence by the use of more sensitive PSA assays in recent years... - Do younger men have better biochemical outcomes after radical prostatectomy?Stephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2101, USA
Urology 63:518-22. 2004..Prior studies have suggested that younger men have lower prostate-specific antigen recurrence rates after RP, although none of the prior studies had controlled for the year of surgery... - Race as an outcome predictor after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) databaseStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, Los Angeles, California 90095-1738, USA
Urology 60:670-4. 2002..The Shared Equal Access Regional Cancer Hospital database is a valuable resource for studying patients treated with RP... - Percent of prostate needle biopsy cores with cancer is significant independent predictor of prostate specific antigen recurrence following radical prostatectomy: results from SEARCH databaseStephen J Freedland
Department of Urology, University of California Los Angeles, Department of Surgery, Veterans Affairs Greater Los Angeles Health Care System, Los Angeles, California 90095, USA
J Urol 169:2136-41. 2003.... - Clinical and pathologic outcome after radical prostatectomy for prostate cancer patients with a preoperative Gleason sum of 8 to 10Patrick J Bastian
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Cancer 107:1265-72. 2006..Whereas multimodal therapy has often meant radiation plus hormonal therapy, newer possibilities for multimodal therapy exist such as surgery with neoadjuvant or adjuvant chemohormonal therapy or surgery with adjuvant radiation... - Should a positive surgical margin following radical prostatectomy be pathological stage T2 or T3? Results from the SEARCH databaseStephen J Freedland
Department of Urology, University of California Los Angeles and Department of Surgery, Veterans Affairs Greater Los Angeles Health Care System, Los Angeles, California 90095, USA
J Urol 169:2142-6. 2003..We examined the significance of the pathological features of positive surgical margin and extracapsular extension for predicting biochemical failure following radical prostatectomy... - Comparison of preoperative prostate specific antigen density and prostate specific antigen for predicting recurrence after radical prostatectomy: results from the search data baseStephen J Freedland
Department of Urology, University of California-Los Angeles School of Medicine, USA
J Urol 169:969-73. 2003..The minimal and statistically insignificant improvement in preoperative risk assessment provided by PSA density does not justify the time and effort necessary to calculate this value... - The percentage of prostate needle biopsy cores with carcinoma from the more involved side of the biopsy as a predictor of prostate specific antigen recurrence after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARStephen J Freedland
Department of Urology, University of California-Los Angeles, Los Angeles, California, USA
Cancer 98:2344-50. 2003..Using the percentage of cores from the dominant side along with the PSA level and the biopsy Gleason score provided significant risk stratification for PSA failure... - Preoperative model for predicting prostate specific antigen recurrence after radical prostatectomy using percent of biopsy tissue with cancer, biopsy Gleason grade and serum prostate specific antigenStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Urol 171:2215-20. 2004..We developed a preoperative model to risk stratify patients for prostate specific antigen (PSA) failure following radical prostatectomy (RP) and identify those at high risk who would be potential candidates for neoadjuvant clinical trials... - Multiinstitutional validation of the UCSF cancer of the prostate risk assessment for prediction of recurrence after radical prostatectomyMatthew R Cooperberg
Department of Urology, Program in Urologic Oncology, Urologic Outcomes Research Group, UCSF Comprehensive Cancer Center, University of California, San Francisco, California 94143, USA
Cancer 107:2384-91. 2006..This study used a large external dataset to validate CAPRA... - Radical prostatectomy for clinical stage T3a diseaseStephen J Freedland
Departments of Urology and Oncology, James Buchanan Brady Urological Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA
Cancer 109:1273-8. 2007..The long-term outcomes among men treated with radical prostatectomy for clinical stage T3a disease were examined... - Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor systemStephen J Freedland
Department of Urology, UCLA, Los Angeles, California 90095-1738, USA
Prostate 55:299-307. 2003..Clonal tumor lines may allow more accurate examination of molecular pathways involved in tumor progression and resistance to treatment... - Biochemical outcome after radical prostatectomy among men with normal preoperative serum prostate-specific antigen levelsStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 2101, USA
Cancer 101:748-53. 2004..Whether malignancies in such men are associated with better outcomes is unclear. The authors compared the risk of biochemical failure after radical prostatectomy (RP) between men with normal PSA levels and men with elevated PSA levels... 
Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after radical prostatectomyBruce J Trock
Brady Urological Institute, Johns Hopkins School of Medicine, 600 N Wolfe St, 546 Phipps Bldg, Baltimore, MD 21287, USA
JAMA 299:2760-9. 2008....- Death in patients with recurrent prostate cancer after radical prostatectomy: prostate-specific antigen doubling time subgroups and their associated contributions to all-cause mortalityStephen J Freedland
Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Medicine, Baltimore, MD, USA
J Clin Oncol 25:1765-71. 2007..However, given the small number of patients in the highest risk PSADT subgroup, it is unclear which PSADT subgroups contribute the greatest to prostate cancer-specific death and how this influences all-cause mortality... - Preoperative p27 status is an independent predictor of prostate specific antigen failure following radical prostatectomyStephen J Freedland
Department of Urology, University of California, Los Angeles, 90095-1738, USA
J Urol 169:1325-30. 2003..5-fold increased risk of biochemical recurrence. To our knowledge this study is the first to show that p27 status of the prostate needle biopsy specimen can be used before radical prostatectomy to predict biochemical failure... 
Freedom from a detectable ultrasensitive prostate-specific antigen at two years after radical prostatectomy predicts a favorable clinical outcome: analysis of the SEARCH databaseSteven L Chang
Department of Urology, Stanford University Medical Center, Stanford, California 94305, USA
Urology 75:439-44. 2010..Previous studies demonstrate that a PSADT < 9 months after radical prostatectomy is associated with prostate cancer-specific mortality. Conventionally, PSADT has been calculated after biochemical failure (PSA > or = 2 0.2 ng/mL)...- Predicting biochemical recurrence after radical prostatectomy for patients with organ-confined disease using p27 expressionStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, 90095 1738, USA
Urology 61:1187-92. 2003..We sought to determine whether p27 staining in the PNBx specimen might serve as a molecular marker for PSA failure in the subset of patients who develop PSA recurrence despite organ-confined disease at RP... - Improved risk stratification for biochemical recurrence after radical prostatectomy using a novel risk group system based on prostate specific antigen density and biopsy Gleason scoreStephen J Freedland
Department of Urology, University of California Los Angeles School of Medicine and Veterans Administration Greater Los Angeles Healthcare System, 90095-1738, USA
J Urol 168:110-5. 2002.... - Pathological outcomes and biochemical progression in men with T1c prostate cancer undergoing radical prostatectomy with prostate specific antigen 2.6 to 4.0 vs 4.1 to 6.0 ng/mlDanil V Makarov
James Buchanan Brady Urological Institute, and the Department of Urology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
J Urol 176:554-8. 2006..5 ng/ml as opposed to the more traditional greater than 4.0 ng/ml. We compared outcomes between men with clinical stage T1c disease undergoing radical prostatectomy who had a low vs slightly increased prostate specific antigen... - Clinical utility of percent prostate needle biopsy tissue with cancer cutpoints to risk stratify patients before radical prostatectomyStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, Los Angeles, California 90095-1738, USA
Urology 60:84-8. 2002..These cutpoints could further stratify patients preoperatively who were at intermediate or high risk of biochemical failure on the basis of PSA and biopsy Gleason score... - Obesity, serum prostate specific antigen and prostate size: implications for prostate cancer detectionStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Urol 175:500-4; discussion 504. 2006..We examined the association between BMI, and PSA and prostate weight in a cohort of men undergoing RP... - Weight gain is associated with an increased risk of prostate cancer recurrence after prostatectomy in the PSA eraCorinne E Joshu
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Rm E6137, Baltimore, MD 21205, USA
Cancer Prev Res (Phila) 4:544-51. 2011..Physical activity (≥ 5 h/wk) did not attenuate risk in men who gained more than 2.2 kg. By avoiding weight gain, men with prostate cancer may both prevent recurrence and improve overall well-being... - Defining the ideal cutpoint for determining PSA recurrence after radical prostatectomy. Prostate-specific antigenStephen J Freedland
Department of Urology, University of California, Los Angeles, School of Medicine, Los Angeles, California 90095-1738, USA
Urology 61:365-9. 2003..2 ng/mL are at very high risk of developing an additional rise in PSA. On the basis of this finding, a PSA value greater than 0.2 ng/mL is an appropriate cutpoint to define PSA recurrence after RP... - Time to prostate specific antigen recurrence after radical prostatectomy and risk of prostate cancer specific mortalityStephen J Freedland
Department of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins Medicine, Baltimore, Maryland, USA
J Urol 176:1404-8. 2006..These data suggest that perhaps time to prostate specific antigen recurrence may be a reasonable intermediate end point in patients treated with radical prostatectomy, although this must be validated in other studies... - Biopsy indication--a predictor of pathologic stage among men with preoperative serum PSA levels of 4.0 ng/mL or less and T1c diseaseStephen J Freedland
James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287-2101, USA
Urology 63:887-91. 2004.... - Effect of altering dietary omega-6/omega-3 fatty acid ratios on prostate cancer membrane composition, cyclooxygenase-2, and prostaglandin E2Naoko Kobayashi
Department of Urology, Division of Clinical Nutrition and Hematology-Oncology, University of California, Los Angeles School of Medicine, 90095-1738, USA
Clin Cancer Res 12:4662-70. 2006.... - Delay of radical prostatectomy and risk of biochemical progression in men with low risk prostate cancerStephen J Freedland
Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
J Urol 175:1298-302; discussion 1302-3. 2006..Whether delays and especially prolonged delays, eg greater than 180 days, before RP negatively impact the disease outcome is unclear... - Health-related quality-of-life outcomes after anatomic retropubic radical prostatectomy in the phosphodiesterase type 5 ERA: impact of neurovascular bundle preservationMichael C Haffner
Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21287-2101, USA
Urology 66:371-6. 2005..CONCLUSIONS: In the current study, bilateral nerve-sparing RP was associated with better postoperative sexual HRQOL scores than unilateral nerve-sparing RP, although in general the differences were slight... - Black race does not independently predict adverse outcome following radical retropubic prostatectomy at a tertiary referral centerMatthew E Nielsen
Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Urol 176:515-9. 2006..However, on multivariate analysis black race was not an independent predictor of adverse pathological outcome or biochemical recurrence. Further efforts are needed to detect prostate cancer earlier among black men... - Predictors of metastatic disease in men with biochemical failure following radical prostatectomyOnisuru T Okotie
Department of Urology, University of California-Los Angeles School of Medicine, Los Angeles, California, USA
J Urol 171:2260-4. 2004..These results have important implications for the timing of imaging in patients with biochemical recurrence following RP... - Evaluating the PCPT risk calculator in ten international biopsy cohorts: results from the Prostate Biopsy Collaborative GroupDonna P Ankerst
Department of Urology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229, USA
World J Urol 30:181-7. 2012.... - Phase II prospective randomized trial of a low-fat diet with fish oil supplementation in men undergoing radical prostatectomyWilliam J Aronson
Department of Urology, School of Medicine, University of California Los Angeles, Box 951738, Los Angeles, CA 90095, USA
Cancer Prev Res (Phila) 4:2062-71. 2011..These results support further studies evaluating reduction of dietary fat with fish oil supplementation on modulating prostate cancer biology... - Statin drugs, serum cholesterol, and prostate-specific antigen in the National Health and Nutrition Examination Survey 2001-2004Alison M Mondul
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Cancer Causes Control 21:671-8. 2010..We evaluated the associations of statins and serum cholesterol with PSA to understand whether the inverse associations of statins and low cholesterol with aggressive prostate cancer are explained by detection bias... - Insight on pathogenesis of varicoceles: relationship of varicocele and body mass indexMatthew E Nielsen
Department of Urology, Johns Hopkins Hospital, Baltimore, Maryland, USA
Urology 68:392-6. 2006..We examined this hypothesis in a large adult population... - Quality of life, pain and return to normal activities following laparoscopic donor nephrectomy versus open mini-incision donor nephrectomyKent T Perry
Department of Urology, University of California-Los Angeles, Los Angeles, California, USA
J Urol 169:2018-21. 2003..In addition, the laparoscopic group showed significantly higher quality of life scores than the mini-incision group in 3 domains... - Loss of CD10 (neutral endopeptidase) is a frequent and early event in human prostate cancerStephen J Freedland
Department of Urology, UCLA School of Medicine, Los Angeles, CA 90095-1738, USA
Prostate 55:71-80. 2003.... - Collecting duct renal cell carcinoma: clinical study of a rare tumorDebby Chao
Department of Urology, Division of Urologic Oncology, University of California School of Medicine-Los Angeles, Los Angeles, CA, USA
J Urol 167:71-4. 2002..Previously recommended chemotherapy and/or immunotherapy appears to have a limited role in treatment of this disease, and early detection may be the best method for prolonging patient survival... - Upgrading and downgrading of prostate needle biopsy specimens: risk factors and clinical implicationsStephen J Freedland
Department of Surgery, Durham Veterans Affairs Medical Center, Durham, North Carolina, USA
Urology 69:495-9. 2007..Given the critical role that needle biopsy plays in treatment decisions, we sought to determine the risk factors for upgrading and downgrading the prostate biopsy specimen... - Risk stratification for biochemical recurrence in men with positive surgical margins or extracapsular disease after radical prostatectomy: results from the SEARCH databaseJayakrishnan Jayachandran
Division of Urologic Surgery, Department of Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
J Urol 179:1791-6; discussion 1796. 2008..We further stratified these men into a low risk group in which watchful waiting after surgery may be preferred and a high risk cohort in which adjuvant therapy may be preferred... - Percent tumor involvement and risk of biochemical progression after radical prostatectomyEdward N Rampersaud
Division of Urologic Surgery, Duke Prostate Center, Durham, North Carolina, USA
J Urol 180:571-6; discussion 576. 2008..We hypothesized percent tumor involvement may be a good correlate of outcome in all stages of prostate cancer... - Obesity and oncological outcome after radical prostatectomy: impact of prostate-specific antigen-based prostate cancer screening: results from the Shared Equal Access Regional Cancer Hospital and Duke Prostate Center databasesStephen J Freedland
Urology Section, Department of Surgery, Veterans Affairs Medical Center, Duke University Medical Center, Durham, NC 27710, USA
BJU Int 102:969-74. 2008.... - Obesity and positive surgical margins by anatomic location after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital databaseJayakrishnan Jayachandran
Urology Section, Veterans Affairs Medical Center, Duke University School of Medicine, Durham, NC 27710, USA
BJU Int 102:964-8. 2008.... - What are the factors associated with short prostate specific antigen doubling time after radical prostatectomy? A report from the SEARCH database groupAnna E Teeter
Division of Urologic Surgery and Duke Prostate Center, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
J Urol 180:1980-4; discussion 1985. 2008..We determined which demographic and clinicopathological variables were predictive of a short prostate specific antigen doubling time in a cohort of men with clinically localized prostate cancer treated with radical prostatectomy... - Percent prostate needle biopsy tissue with cancer is more predictive of biochemical failure or adverse pathology after radical prostatectomy than prostate specific antigen or Gleason scoreStephen J Freedland
Departments of Urology and Biostatistics, UCLA School of Medicine, Los Angeles 90095-1738, USA
J Urol 167:516-20. 2002..Consideration should be given to reporting percent of total biopsy tissue with cancer in all prostate biopsy results... - The effect of race/ethnicity on the accuracy of the 2001 Partin Tables for predicting pathologic stage of localized prostate cancerElisabeth I Heath
Barbara Ann Karmanos Cancer Institute, Department of Hematology and Oncology, Wayne State University, 4100 John R, 4 HWCRC, Detroit, MI 48201, USA
Urology 71:151-5. 2008..To test the accuracy of the 2001 Partin Tables in African American men who underwent radical prostatectomy at multiple centers throughout the United States... - Rising PSA in nonmetastatic prostate cancerJudd W Moul
Division of Urologic Surgery, Duke Prostate Center, Duke University Medical Center, Durham, NC 27710, USA
Oncology (Williston Park) 21:1436-45; discussion 1449, 1452, 1454. 2007..In this article, we will explore these prostate cancer disease states with an emphasis on practical, clinically applicable approaches... - Optimal timing, cutoff, and method of calculation of preoperative prostate-specific antigen velocity to predict relapse after prostatectomy: a report from SEARCHChristopher R King
Department of Radiation Oncology, Division of Urologic Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
Urology 69:732-7. 2007..We studied the timing, cutoff levels, and method of calculation to better define its usefulness... - Body mass index, weight change, and risk of prostate cancer in the Cancer Prevention Study II Nutrition CohortCarmen Rodriguez
Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road Northeast, Atlanta, GA 30329 4251, USA
Cancer Epidemiol Biomarkers Prev 16:63-9. 2007..Obesity has been associated with aggressive prostate cancer. The extent of this association, which varies by stage and grade, remains unclear. The role of recent weight change had not been previously examined... - Is biopsy Gleason score independently associated with biochemical progression following radical prostatectomy after adjusting for pathological Gleason score?Nicholas J Fitzsimons
Division of Urologic Surgery, Duke Prostate Center, University Medical Center, Duke University School of Medicine, Durham, NC 27710, USA
J Urol 176:2453-8; discussion 2458. 2006..However, it is unclear whether it remains associated with outcome after surgery when the pathological Gleason score is known... - Impact of obesity on the utility of preoperative prostate-specific antigen velocity to predict for relapse after prostatectomy: a report from the SEARCH databaseChristopher R King
Division of Urologic Oncology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
Urology 69:921-6. 2007.... - Prostate specific antigen recurrence after definitive therapyStephen J Freedland
Division of Surgery, Durham Veterans Affairs Medical Center, Durham, NC, USA
J Urol 177:1985-91. 2007..However, to do so the risks and benefits of the various options must be known. Therefore, we provide a comprehensive overview of the natural history and treatment options for men with prostate specific antigen-only recurrence... - Predicting unilateral prostate cancer based on biopsy features: implications for focal ablative therapy--results from the SEARCH databaseCharles D Scales
Department of Surgery Division of Urologic Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
J Urol 178:1249-52. 2007..However, few studies have assessed the correlation between biopsy parameters and pathological outcome (unilateral vs bilateral disease)... - Risk stratification of men with Gleason score 7 to 10 tumors by primary and secondary Gleason score: results from the SEARCH databaseDavid E Kang
Division of Urologic Surgery, Department of Surgery and Duke Prostate Center, Duke University School of Medicine, Durham, North Carolina, USA
Urology 70:277-82. 2007..Whether the increased risk associated with Gleason score 4+3 disease is equivalent to that of Gleason score 4+4 or greater is unclear... - PSA in the new millennium: a powerful predictor of prostate cancer prognosis and radical prostatectomy outcomes--results from the SEARCH databaseStephen J Freedland
Urology Section, Veterans Affairs Medical Center, Durham, NC, USA
Eur Urol 53:758-64; discussion 765-6. 2008..We examined the prognostic significance of preoperative PSA to predict pathologic stage and biochemical progression among men undergoing radical prostatectomy in the new millennium (2000-2006)... - Is a positive bladder neck margin truly a T4 lesion in the prostate specific antigen era? Results from the SEARCH DatabaseW Cooper Buschemeyer
Department of Surgery Division of Urologic Surgery, Duke University School of Medicine and Urology Section, Surgical Service, Veterans Affairs Medical Center Durham, Durham, North Carolina 27710, USA
J Urol 179:124-9; discussion 129. 2008..We examined the association between positive bladder neck margins and prostate specific antigen recurrence relative to other pathological findings... - Small transrectal ultrasound volume predicts clinically significant Gleason score upgrading after radical prostatectomy: results from the SEARCH databaseRyan S Turley
Division of Urological Surgery, Duke Prostate Center, Duke University School of Medicine, Durham, North Carolina, USA
J Urol 179:523-7; discussion 527-8. 2008..We examined the likelihood of clinically relevant upgrading after radical prostatectomy as a function of transrectal ultrasound volume... - Obesity and prostate cancer: making sense out of apparently conflicting dataStephen J Freedland
Department of Surgery, Veterans Affairs Medical Center, Durham, NC 27710, USA
Epidemiol Rev 29:88-97. 2007..Emerging data suggest a differential effect of obesity by disease aggressiveness: obesity may reduce the risk of nonaggressive disease while it may promote aggressive disease...