C E Frangakis

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. pmc Application of the propensity score in a covariate-based linkage analysis of the Collaborative Study on the Genetics of Alcoholism
    Betty Q Doan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    BMC Genet 6:S33. 2005
  2. ncbi request reprint Addressing an idiosyncrasy in estimating survival curves using double sampling in the presence of self-selected right censoring
    C E Frangakis
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 57:333-42. 2001
  3. ncbi request reprint Compliance subsampling designs for comparative research: estimation and optimal planning
    C E Frangakis
    Department of Biostatistics, The Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 57:899-908. 2001
  4. ncbi request reprint Principal stratification in causal inference
    Constantine E Frangakis
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 58:21-9. 2002
  5. ncbi request reprint Confidence intervals for seasonal relative risk with null boundary values
    Constantine E Frangakis
    Department of Biostatistics, John Hopkins University, Baltimore, MD 21205, USA
    Epidemiology 13:734-7. 2002
  6. ncbi request reprint Principal stratification designs to estimate input data missing due to death
    Constantine E Frangakis
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 63:641-9; discussion 650-62. 2007
  7. pmc Multiple imputation with large data sets: a case study of the Children's Mental Health Initiative
    Elizabeth A Stuart
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 169:1133-9. 2009
  8. ncbi request reprint High HIV sexual risk behaviors and sexually transmitted disease prevalence among injection drug users in Northern Vietnam: implications for a generalized HIV epidemic
    Vivian F Go
    Infectious Diseases Program, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 42:108-15. 2006
  9. pmc Characteristics of high-risk HIV-positive IDUs in Vietnam: implications for future interventions
    Vivian F Go
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Subst Use Misuse 46:381-9. 2011
  10. pmc Application of a propensity score approach for risk adjustment in profiling multiple physician groups on asthma care
    I Chan Huang
    Department of Health Policy and Management, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205 1901, USA
    Health Serv Res 40:253-78. 2005

Research Grants

Detail Information

Publications23

  1. pmc Application of the propensity score in a covariate-based linkage analysis of the Collaborative Study on the Genetics of Alcoholism
    Betty Q Doan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    BMC Genet 6:S33. 2005
    ..Several definitions of the PS were calculated, each with increasing number of covariates up to a maximum of five. To account for the potential inflation in the type I error rates, permutation based p-values were calculated...
  2. ncbi request reprint Addressing an idiosyncrasy in estimating survival curves using double sampling in the presence of self-selected right censoring
    C E Frangakis
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 57:333-42. 2001
    ..We evaluate our method in a realistic situation by simulating data that match published margins on survival and dropout from an actual hip-replacement study. Limitations and extensions of our design and analytic method are discussed...
  3. ncbi request reprint Compliance subsampling designs for comparative research: estimation and optimal planning
    C E Frangakis
    Department of Biostatistics, The Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 57:899-908. 2001
    ..We compare the properties of the CSS design to those of conventional protocols in a study of patient choices for medical care at the end of life...
  4. ncbi request reprint Principal stratification in causal inference
    Constantine E Frangakis
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 58:21-9. 2002
    ..We go on to forrmulate estimands based on principal stratification and principal causal effects and show their superiority...
  5. ncbi request reprint Confidence intervals for seasonal relative risk with null boundary values
    Constantine E Frangakis
    Department of Biostatistics, John Hopkins University, Baltimore, MD 21205, USA
    Epidemiology 13:734-7. 2002
    ..We apply our method to seasonal suicide data from a recent report...
  6. ncbi request reprint Principal stratification designs to estimate input data missing due to death
    Constantine E Frangakis
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Biometrics 63:641-9; discussion 650-62. 2007
    ..Thus, our approach suggests that the routine collection of data on variables that could be used as possible treatments in such studies of inputs and mortality should become common...
  7. pmc Multiple imputation with large data sets: a case study of the Children's Mental Health Initiative
    Elizabeth A Stuart
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 169:1133-9. 2009
    ..This case study provides an illustration to assist researchers in implementing multiple imputation in their own data...
  8. ncbi request reprint High HIV sexual risk behaviors and sexually transmitted disease prevalence among injection drug users in Northern Vietnam: implications for a generalized HIV epidemic
    Vivian F Go
    Infectious Diseases Program, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 42:108-15. 2006
    ..HIV prevalence in Vietnam is currently concentrated among injection drug users (IDUs). The extent to which this core risk group represents a potential for broader HIV transmission to the general population is currently unknown...
  9. pmc Characteristics of high-risk HIV-positive IDUs in Vietnam: implications for future interventions
    Vivian F Go
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Subst Use Misuse 46:381-9. 2011
    ..Structural interventions that increase syringe accessibility may be effective in reducing HIV risk behavior among HIV-positive IDUs. Study limitations are noted in the article...
  10. pmc Application of a propensity score approach for risk adjustment in profiling multiple physician groups on asthma care
    I Chan Huang
    Department of Health Policy and Management, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205 1901, USA
    Health Serv Res 40:253-78. 2005
    ..To develop a propensity score-based risk adjustment method to estimate the performance of 20 physician groups and to compare performance rankings using our method to a standard hierarchical regression-based risk adjustment method...
  11. ncbi request reprint Is risk-adjustor selection more important than statistical approach for provider profiling? Asthma as an example
    I Chan Huang
    Department of Health Policy and Management, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland 21205 1901, USA
    Med Decis Making 25:20-34. 2005
    ..To examine how the selections of different risk adjustors and statistical approaches affect the profiles of physician groups on patient satisfaction...
  12. ncbi request reprint Modelling risk factors for injuries from dog bites in Greece: a case-only design and analysis
    Constantine E Frangakis
    Department of Biostatistics, Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Accid Anal Prev 35:435-8. 2003
    ..Moreover, after controlling for these factors, risk of bite injury was not associated with moon periods, thereby also helping settle a longstanding argument...
  13. ncbi request reprint Design of Depression in Alzheimer's Disease Study-2
    Barbara K Martin
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Geriatr Psychiatry 14:920-30. 2006
    ....
  14. ncbi request reprint Polydesigns and causal inference
    Fan Li
    Department of Biostatistics, The Johns Hopkins University, 615 N Wolfe Street, Baltimore, Maryland 21205, USA
    Biometrics 62:343-51. 2006
    ..We discuss implementation of polydesign methods, and provide an illustration in the evaluation of a needle exchange program...
  15. ncbi request reprint Revealing and addressing length bias and heterogeneous effects in frequency case-crossover studies
    Ravi Varadhan
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Am J Epidemiol 159:596-602. 2004
    ..A new method of analysis is presented that is free from length bias and that efficiently uses gap time data...
  16. ncbi request reprint Estimating the population burden of injuries: a comparison of household surveys and emergency department surveillance
    Eleni Petridou
    Department of Hygiene and Epidemiology, Athens University Medical School, Athens, Greece
    Epidemiology 15:428-32. 2004
    ..Injuries represent an important public health problem but their incidence is difficult to estimate...
  17. ncbi request reprint Exploring lag and duration effect of sunshine in triggering suicide
    Fotios C Papadopoulos
    Department of Hygiene and Epidemiology, Athens University Medical School, 75 M Asias str, Goudi, P O Box 11527, Athens, Greece
    J Affect Disord 88:287-97. 2005
    ..Sunshine is considered to have a beneficial impact on mood. Interestingly, it has been consistently found that the incidence of suicide reaches a peak during early summer...
  18. ncbi request reprint Designs in partially controlled studies: messages from a review
    Fan Li
    Department of Biostatistics, Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Stat Methods Med Res 14:417-31. 2005
    ..Based on the review, we give two complementary reasons that explain the limited work on such designs, and suggest a new direction in this area...
  19. ncbi request reprint Covariate-based linkage analysis: application of a propensity score as the single covariate consistently improves power to detect linkage
    Betty Q Doan
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Eur J Hum Genet 14:1018-26. 2006
    ....
  20. pmc Water safety: age-specific changes in knowledge and attitudes following a school-based intervention
    Agis Terzidis
    Department of Hygiene and Epidemiology, Athens University Medical School, Athens, Greece
    Inj Prev 13:120-4. 2007
    ..To explore whether an intervention during mandatory schooling can lead to age-specific changes in water safety knowledge and attitudes...
  21. ncbi request reprint Burn injuries related to motorcycle exhaust pipes: a study in Greece
    Ioannis Matzavakis
    Department of Hygiene and Epidemiology, Athens University Medical School, 75 Mikras Asias Street, 11527 Athens, Greece
    Burns 31:372-4. 2005
    ..To identify measures that should reduce the incidence of burn injuries resulting from motorcycle exhaust pipes through epidemiological analysis of such injuries...
  22. ncbi request reprint Using propensity scores subclassification to estimate effects of longitudinal treatments: an example using a new diabetes medication
    Jodi B Segal
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Med Care 45:S149-57. 2007
    ..When using observational data to compare the effectiveness of medications, it is essential to account parsimoniously for patients' longitudinal characteristics that lead to changes in treatments over time...
  23. ncbi request reprint A role of sunshine in the triggering of suicide
    Eleni Petridou
    Department of Hygiene and Epidemiology, Athens University Medical School, Greece
    Epidemiology 13:106-9. 2002
    ..These findings indicate that sunshine may have a triggering effect on suicide, and suggests further research in the field of sunshine-regulated hormones, particularly melatonin...

Research Grants7

  1. Statistical Methods for Partially Controlled Studies
    Constantine Frangakis; Fiscal Year: 2005
    ..This work is essential for preserving generalizability of results from long follow-up studies, and we will apply it to better evaluate time to potential drug dependence in youths. ..
  2. Statistical Designs and Methods for Partially Controlled HIV/AIDS Studies
    Constantine Frangakis; Fiscal Year: 2007
    ..Our methods are motivated and will be applied to the first cell-mediated immunity HIV vaccine trial (Step trial), and to the Mashi trial on mother-to-child HIV transmission. ..
  3. Statistical Designs and Methods for Partially Controlled HIV/AIDS Studies
    Constantine E Frangakis; Fiscal Year: 2010
    ..Our methods are motivated and will be applied to the first cell-mediated immunity HIV vaccine trial (Step trial), and to the Mashi trial on mother-to-child HIV transmission. ..