Research Topics
Species | Howard W FrancisSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Surgical factors in pediatric cochlear implantation and their early effects on electrode activation and functional outcomesHoward W Francis
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21287 0910, USA
Otol Neurotol 29:502-8. 2008..To assess the impact of surgical factors on electrode status and early communication outcomes in young children in the first 2 years of cochlear implantation...
Impact of cochlear implants on the functional health status of older adultsHoward W Francis
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Laryngoscope 112:1482-8. 2002..To assess the impact of cochlear implantation on quality of life changes in older adults aged 50 years and above...- Cochlear implantation updateHoward W Francis
Otolaryngology Head and Neck Surgery, Johns Hopkins University, 601 N Caroline Street, JHOC, 6th Floor, Baltimore, MD 21287, USA
Pediatr Clin North Am 50:341-61, viii. 2003..There are early indications that increased access to mainstream education and gains in quality of life are long-term benefits that render cochlear implantation a cost-effective intervention... - The functional age of hearing loss in a mouse model of presbycusis. II. Neuroanatomical correlatesHoward W Francis
Department of Otolaryngology HNS, Johns Hopkins University, 601 North Caroline Street, Baltimore, MD 21287, USA
Hear Res 183:29-36. 2003..In the absence of physiologically defined cochlear frequency maps for C57BL/6J mice, these structure-function correlation techniques offer an alternative approach for linking anatomical results to hearing abilities... - Effects of central nervous system residua on cochlear implant results in children deafened by meningitisHoward W Francis
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University, Baltimore, MD, USA
Arch Otolaryngol Head Neck Surg 130:604-11. 2004..This study explored factors associated with speech recognition outcomes in postmeningitic deafness (PMD). The results of cochlear implantation may vary in children with PMD because of sequelae that extend beyond the auditory periphery... - Efficient quantification of afferent cochlear ultrastructure using design-based stereologyHoward W Francis
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, 601N Caroline St, JHOC 6th Floor, Baltimore, MD 21205, USA
J Neurosci Methods 150:150-8. 2006..We conclude that ultrastructural quantification of afferent innervation can be accomplished in the cochlea using efficient design-based stereology... - Two types of afferent terminals innervate cochlear inner hair cells in C57BL/6J miceHoward W Francis
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, 720 Rutland Avenue, Baltimore, MD 21205, USA
Brain Res 1016:182-94. 2004..In many cases, the double membrane was continuous with the outer terminal membrane as if produced by an invagination. We still must determine the generality of these observations with respect to other mouse strains... 
Objective assessment of mastoidectomy skills in the operating roomHoward W Francis
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA
Otol Neurotol 31:759-65. 2010..To determine the feasibility and validity of an objective assessment tool designed to measure the development of mastoidectomy skills by resident trainees in the operating room...- Sex and age associations with vestibular schwannoma size and presenting symptomsAisha Harun
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Otol Neurotol 33:1604-10. 2012..To assess the association of sex and age with presenting symptoms and size of vestibular schwannoma at clinical presentation to our clinics... - Hearing outcomes after surgical plugging of the superior semicircular canal by a middle cranial fossa approachBryan K Ward
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Otol Neurotol 33:1386-91. 2012..To determine postoperative hearing outcomes after surgical plugging via middle cranial fossa approach for superior semicircular canal dehiscence syndrome (SCDS)... - Timing of cochlear implantation and parents' global ratings of children's health and developmentJames H Clark
Department of Otolaryngology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Otol Neurotol 33:545-52. 2012..To assess children's health-related quality of life (HRQL) and development after cochlear implant (CI) surgery and compare improvements between different age of implantation categories... - Risk factors for vagal palsy following cerebellopontine angle surgerySimon R Best
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Medical Institution, Baltimore, Maryland 21287, USA
Otolaryngol Head Neck Surg 147:364-8. 2012..Describe the incidence, risk factors, and outcomes of postoperative vagal palsy in patients undergoing surgical excision of cerebellopontine angle (CPA) tumors... - Revision cochlear implant surgery in children: the Johns Hopkins experienceAndrea L Marlowe
The Listening Center, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21287, USA
Otol Neurotol 31:74-82. 2010..To assess the efficacy of revision cochlear implantation (RCI) and to identify clinical and device-related factors predictive of RCI outcome... - Technical skills improve after practice on virtual-reality temporal bone simulatorHoward W Francis
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA
Laryngoscope 122:1385-91. 2012..To assess whether practice on a virtual-reality (VR) temporal bone simulator improves acquisition of technical skills in mastoid surgery... - Task performance in stapedotomy: comparison between surgeons of different experience levelsDaniel L Rothbaum
Department of Otolaryngology Head and Neck Surgery, Center for Computer Integrated Surgical Systems and Technology, Johns Hopkins University, Baltimore, MD 21287, USA
Otolaryngol Head Neck Surg 128:71-7. 2003..We conducted trials to determine if experience correlates with differences in performance for these tasks... - National prevalence and impact of perioperative vagus nerve injury in vestibular schwannomaBryan K Ward
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA
Laryngoscope 122:2824-31. 2012..This study aims to characterize the prevalence of complications associated with vagus nerve injury following vestibular schwannoma surgery and the impact of these complications on patient care... - Cochlear implantation in older adultsFrank R Lin
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Medicine (Baltimore) 91:229-41. 2012.... - Defining milestones toward competency in mastoidectomy using a skills assessment paradigmHoward W Francis
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21287, USA
Laryngoscope 120:1417-21. 2010..To establish milestones toward achievement of surgical competency by using an objective assessment tool designed to measure the development of mastoidectomy skills in the operating room (OR)... - Predictive models for cochlear implantation in elderly candidatesJanice Leung
Division of Otology, Neurotology, and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
Arch Otolaryngol Head Neck Surg 131:1049-54. 2005..This study confirms and extends previous observations that duration of profound deafness and residual speech recognition carry higher predictive value than the age at which an individual receives an implant... - The timely completion of objective assessment tools for evaluation of technical skillsKulsoom Laeeq
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, U S A
Laryngoscope 122:2418-21. 2012..The goal of our study was to assess the effect of time taken to complete an evaluation on its validity... - Cochlear implant outcome is not influenced by the choice of earHoward W Francis
The Listening Center, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA
Ear Hear 26:7S-16S. 2005.... - Spectrum of immune-mediated inner ear disease and cochlear implant resultsMohammad U Malik
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, U S A
Laryngoscope 122:2557-62. 2012..To characterize the progression of hearing loss in patients with immune-mediated inner ear disease (IMIED), and to identify disease- and patient-specific factors associated with cochlear implant (CI) performance... - Cochlear implant rehabilitation in older adults: literature review and proposal of a conceptual frameworkJames H Clark
Department of Otolaryngology Head and Neck Surgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland
J Am Geriatr Soc 60:1936-45. 2012..To review studies investigating cochlear implant (CI) outcomes in older adults, and to develop a conceptual framework demonstrating important interactions between characteristics of hearing disability, aging, and the CI intervention... - Pilot testing of an assessment tool for competency in mastoidectomyKulsoom Laeeq
Department Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA
Laryngoscope 119:2402-10. 2009..This study tests the hypothesis that residents of dissimilar training levels differ in their technical performance as measured by this tool... - Synaptic alterations at inner hair cells precede spiral ganglion cell loss in aging C57BL/6J miceSofia Stamataki
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, 720 Rutland Avenue, Baltimore, MD 21205, USA
Hear Res 221:104-18. 2006..Improved knowledge of these processes is necessary to understand the role of afferent connectivity in dysfunction of the aging cochlea... - Revision cochlear implantation surgery in adults: indications and resultsAlejandro Rivas
The Listening Center, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA
Otol Neurotol 29:639-48. 2008..To assess the efficacy, risks, and indications of revision cochlear implantation (RCI) and to identify the clinical, audiologic, and device-related characteristics that predict outcome... - Prevalence, characteristics, and management of swallowing disorders following cerebellopontine angle surgeryHeather M Starmer
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Otolaryngol Head Neck Surg 146:419-25. 2012..To describe swallowing disorders encountered after cerebellopontine angle surgery and to explore variables associated with increased incidence of postoperative dysphagia... - Predictors of vestibular schwannoma growth and clinical implicationsYuri Agrawal
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Otol Neurotol 31:807-12. 2010..We evaluated the extent to which tumor growth influences the management of these benign tumors, and we explored symptom markers present at diagnosis that may be predictive of tumor growth... - Development and pilot testing of an objective structured clinical examination (OSCE) on hoarsenessC Matthew Stewart
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, Maryland, USA
Laryngoscope 120:2177-82. 2010..To pilot-test the feasibility by assessing residents' clinical skills in various core competencies while assessing hoarseness on a standardized patient (SP)... - Efferent synapses return to inner hair cells in the aging cochleaAmanda M Lauer
The Center for Hearing and Balance, Department of Otolaryngology HNS, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Neurobiol Aging 33:2892-902. 2012..Age-related reduction of afferent activity may engage signaling pathways that support the return to an immature state of efferent innervation of the cochlea... - Central effects of residual hearing: implications for choice of ear for cochlear implantationHoward W Francis
Listening Center, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD 21287-0910, U.S.A
Laryngoscope 114:1747-52. 2004..Therefore, the central auditory pathway may be the site at which persistent auditory function has its most beneficial effects... - A model for early prediction of facial nerve recovery after vestibular schwannoma surgeryAlejandro Rivas
Department of Otolaryngology Head and Neck Surgery, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Otol Neurotol 32:826-33. 2011..To identify early predictors of long-term facial nerve function after vestibular schwannoma resection... - Arachnoid granulations of the temporal bone: a histologic study of dural and osseous penetrationMargaret Yew
The Johns Hopkins Temporal Bone Laboratory, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA
Otol Neurotol 32:602-9. 2011..Arachnoid granulations (AG) are more prevalent along the middle fossa surface of the temporal bone, where they produce larger bony defects than those occurring on the posterior surface... - Programmatic challenges in obtaining and confirming the pneumococcal vaccination status of cochlear implant recipientsRyan M Carpenter
The Listening Center at Johns Hopkins, Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University, Baltimore, Maryland, USA
Otol Neurotol 31:1334-6. 2010..Bacterial meningitis represents a substantial concern for individuals with cochlear implants (CIs)... - Trends in the management of vestibular schwannomas at Johns Hopkins 1997-2007Marietta Tan
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21287, USA
Laryngoscope 120:144-9. 2010..To assess trends in the management of unilateral vestibular schwannomas over an 11-year period and to identify disease- and provider-related influences... - 3D model of frequency representation in the cochlear nucleus of the CBA/J mouseMichael A Muniak
Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland 21205, USA
J Comp Neurol 521:1510-32. 2013..This model, available online (http://3D.ryugolab.com/), can serve as a tool for quantitatively testing hypotheses concerning frequency and location in the CN... - Inner ear abnormalities in a Kcnq1 (Kvlqt1) knockout mouse: a model of Jervell and Lange-Nielsen syndromeAlejandro Rivas
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA
Otol Neurotol 26:415-24. 2005..Mice lacking functional KCNQ1 (previously known as KvLQT1) channels exhibit functional and structural abnormalities that indicate disturbed production of endolymph... - Spontaneous meningoencephalocele of the temporal bone: clinical spectrum and presentationZayna Nahas
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins Hospital, 601 N Caroline St, JHOC 6251, Baltimore, MD 21287 0910, USA
Arch Otolaryngol Head Neck Surg 134:509-18. 2008..To describe the clinical presentation and the radiological and surgical findings in patients with spontaneous meningoencephalocele of the temporal bone... - Vestibular schwannoma surgical volume and short-term outcomes in MarylandBryan K Ward
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Arch Otolaryngol Head Neck Surg 138:577-83. 2012..To characterize contemporary practice patterns and outcomes of vestibular schwannoma surgery... - Robot-assisted stapedotomy: micropick fenestration of the stapes footplateDaniel L Rothbaum
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins Hospital, MD 21287, USA
Otolaryngol Head Neck Surg 127:417-26. 2002..Performance variables were measured for 3 experienced and 3 less-experienced surgeons... - Temporal bone findings in a case of Susac's syndromeHoward W Francis
Johns Hopkins Hospital, Baltimore, Maryland, USA
Otol Neurotol 32:1198-204. 2011..To describe the histopathologic findings in the temporal bones of a patient with Susac's syndrome (SS)... - Nontypeable Haemophilus influenzae meningitis complicated by hearing loss in a 9-year-old HIV-infected boyAllison George Agwu
Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
AIDS Patient Care STDS 20:531-5. 2006..Placement of cochlear implant improved hearing thresholds. Nontypeable H. influenzae meningitis and use of cochlear implants have not previously been in HIV-infected children... - Histological features of osteofibrous hemangioma of the maxillofacial and skull base regionsSofia Stamataki
Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, USA
Otolaryngol Head Neck Surg 138:587-93. 2008..The histological spectrum of hemangiomas of the skull base and maxillofacial skeleton was evaluated to help explain the variability of the clinical and radiological presentation of this tumor... - Reduction of cerebrospinal fluid rhinorrhea after vestibular schwannoma surgery by reconstruction of the drilled porus acusticus with hydroxyapatite bone cementClinton J Baird
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Neurosurg 107:347-51. 2007..The authors investigated whether reconstruction of the drilled posterior wall of the porus acusticus with hydroxyapatite cement (HAC) would decrease the incidence of postoperative CSF rhinorrhea... - Nasopharyngeal hairy polyp with recurrence in the middle earSteven S Chang
Department Otolaryngology Head and Neck Surgery, Johns Hopkins University, Baltimore, MD 21287, United States
Int J Pediatr Otorhinolaryngol 72:261-4. 2008..Indeed, this case documents progressive growth of a hairy polyp during physical development of a child, and indicates a potential for local recurrence following incomplete excision. A review of possible etiologies is conducted... - Protein kinase C mediates potentiation of synaptic transmission by phorbol ester at parallel fibers in the dorsal cochlear nucleusHoward W Francis
Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Brain Res 951:9-22. 2002..These experiments demonstrate that protein kinase C is capable of profoundly modulating synaptic transmission at parallel fiber synapses in the DCN... - Temporal bone fractureMatthias Ohlrogge
Department of Otolaryngology, Head and Neck Surgery, University of Goettingen, Goettingen, Germany
Otol Neurotol 25:195-6. 2004
Research Grants
- NEUROBIOLOGY OF THE VENTRAL COCHLEAR NUCLEUS IN DEAFNESSHoward Francis; Fiscal Year: 2002....