- Plasminogen activator inhibitor-1 inhibitors: a patent review (2006-present)Yolanda M Fortenberry
Johns Hopkins University School of Medicine, Division of Hematology Department of Pediatrics, 720 Rutland Avenue Ross 1120, Baltimore, MD 21205, USA
Expert Opin Ther Pat 23:801-15. 2013..Consequently, the pharmacological suppression of PAI-1 might prevent or treat vascular disease...
- Essential thrombin residues for inhibition by protein C inhibitor with the cofactors heparin and thrombomodulinY M Fortenberry
Departments of Pathology and Laboratory Medicine, and Pharmacology and Medicine, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA
J Thromb Haemost 5:1486-92. 2007..Background: Protein C inhibitor (PCI) and antithrombin (AT) are serine protease inhibitors (serpins) that inhibit a wide array of blood coagulation serine proteases including thrombin...
- Protein C inhibitor regulates both cathepsin L activity and cell-mediated tumor cell migrationYolanda M Fortenberry
Department of Pediatric Hematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Biochim Biophys Acta 1800:580-90. 2010..However, the physiological role of PCI remains under investigation. The cysteine protease, cathepsin L, has a role in many physiological processes including cardiovascular diseases, blood vessel remodeling, and cancer...