Shannon Fisher

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Evaluating the biological relevance of putative enhancers using Tol2 transposon-mediated transgenesis in zebrafish
    Shannon Fisher
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Nat Protoc 1:1297-305. 2006
  2. ncbi Conservation of RET regulatory function from human to zebrafish without sequence similarity
    Shannon Fisher
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 312:276-9. 2006
  3. ncbi Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
    Jantje M Gerdes
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nat Genet 39:1350-60. 2007
  4. pmc Manipulating mitotic recombination in the zebrafish embryo through RecQ helicases
    Jing Xie
    The McKusick Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Genetics 176:1339-42. 2007
  5. ncbi Radiographic analysis of zebrafish skeletal defects
    Shannon Fisher
    Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210, USA
    Dev Biol 264:64-76. 2003
  6. ncbi Dissection of epistasis in oligogenic Bardet-Biedl syndrome
    Jose L Badano
    McKusick Nathans Institute of Genetic Medicine, Baltimore, Maryland 21205, USA
    Nature 439:326-30. 2006
  7. ncbi Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms
    Jing Xie
    The McKusick Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, 733 N Broadway, BRB 455, Baltimore, MD 21205, USA
    Development 132:383-91. 2005
  8. ncbi Duplicate zebrafish runx2 orthologues are expressed in developing skeletal elements
    Maria Vega Flores
    Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    Gene Expr Patterns 4:573-81. 2004
  9. ncbi Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
    Alison J Ross
    Molecular Medicine Unit, Institute of Child Health, University College London, WC1N 1EH, UK
    Nat Genet 37:1135-40. 2005
  10. ncbi Saltatory control of isometric growth in the zebrafish caudal fin is disrupted in long fin and rapunzel mutants
    Matthew I Goldsmith
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA
    Dev Biol 259:303-17. 2003

Collaborators

Detail Information

Publications10

  1. ncbi Evaluating the biological relevance of putative enhancers using Tol2 transposon-mediated transgenesis in zebrafish
    Shannon Fisher
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Nat Protoc 1:1297-305. 2006
    ..This system is amenable to large-scale application, facilitating rapid functional analysis of noncoding sequences from both mammalian and teleost species...
  2. ncbi Conservation of RET regulatory function from human to zebrafish without sequence similarity
    Shannon Fisher
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 312:276-9. 2006
    ..The majority of human RET noncoding sequences also directed ret-specific expression in zebrafish. Thus, vast amounts of functional sequence information may exist that would not be detected by sequence similarity approaches...
  3. ncbi Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
    Jantje M Gerdes
    McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Nat Genet 39:1350-60. 2007
    ....
  4. pmc Manipulating mitotic recombination in the zebrafish embryo through RecQ helicases
    Jing Xie
    The McKusick Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Genetics 176:1339-42. 2007
    ..We have developed an in vivo assay based on a zebrafish pigment mutant for suppression of RecQ activity, and demonstrate that zebrafish RecQ genes have conserved function in suppressing mitotic recombination...
  5. ncbi Radiographic analysis of zebrafish skeletal defects
    Shannon Fisher
    Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210, USA
    Dev Biol 264:64-76. 2003
    ..Radiography is a practical screening tool to detect subtle skeletal abnormalities in the adult zebrafish. The identification of chihuahua demonstrates that mutant phenotypes analogous to human skeletal dysplasias will be discovered...
  6. ncbi Dissection of epistasis in oligogenic Bardet-Biedl syndrome
    Jose L Badano
    McKusick Nathans Institute of Genetic Medicine, Baltimore, Maryland 21205, USA
    Nature 439:326-30. 2006
    ..Our data demonstrate how the combined use of biochemical, genetic and in vivo tools can facilitate the dissection of epistatic phenomena, and enhance our appreciation of the genetic basis of phenotypic variability...
  7. ncbi Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms
    Jing Xie
    The McKusick Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, 733 N Broadway, BRB 455, Baltimore, MD 21205, USA
    Development 132:383-91. 2005
    ....
  8. ncbi Duplicate zebrafish runx2 orthologues are expressed in developing skeletal elements
    Maria Vega Flores
    Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    Gene Expr Patterns 4:573-81. 2004
    ..While both genes are expressed in developing skeletal elements, they show evidence of partial divergence in expression pattern, possibly explaining why both orthologues have been retained through teleost evolution...
  9. ncbi Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
    Alison J Ross
    Molecular Medicine Unit, Institute of Child Health, University College London, WC1N 1EH, UK
    Nat Genet 37:1135-40. 2005
    ..We also show that Vangl2 localizes to the basal body and axoneme of ciliated cells, a pattern reminiscent of that of the BBS proteins. These data suggest that cilia are intrinsically involved in PCP processes...
  10. ncbi Saltatory control of isometric growth in the zebrafish caudal fin is disrupted in long fin and rapunzel mutants
    Matthew I Goldsmith
    Department of Pediatrics, Washington University School of Medicine, St Louis, MO 63110, USA
    Dev Biol 259:303-17. 2003
    ..Finally, we show that two separate fin overgrowth mutants, long fin and rapunzel, bypass the stasis phase of the fin ray growth cycle to develop asymmetrical and symmetrical fin overgrowth, respectively...

Research Grants2