Stacey D Finley

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Front Oncol 3:196. 2013
  2. pmc Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Natl Cancer Inst 105:802-11. 2013
  3. pmc Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms
    Stacey D Finley
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA
    AAPS J 14:500-9. 2012
  4. pmc Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    BMC Syst Biol 5:193. 2011
  5. pmc A two-compartment model of VEGF distribution in the mouse
    Phillip Yen
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 6:e27514. 2011
  6. pmc A systems biology view of blood vessel growth and remodelling
    Elizabeth A Logsdon
    Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
    J Cell Mol Med 18:1491-508. 2014

Collaborators

Detail Information

Publications6

  1. pmc Compartment model predicts VEGF secretion and investigates the effects of VEGF trap in tumor-bearing mice
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Front Oncol 3:196. 2013
    ..The model predictions also have implications for biomarker discovery with anti-angiogenic therapies. ..
  2. pmc Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Natl Cancer Inst 105:802-11. 2013
    ..These models complement experimental studies and aid in the development of effective therapies targeting angiogenesis...
  3. pmc Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms
    Stacey D Finley
    Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA
    AAPS J 14:500-9. 2012
    ..Targeting VEGF(121) reduces tumor free VEGF and is an effective treatment strategy. Our results provide a basis for clinical investigation of isoform-specific anti-VEGF agents...
  4. pmc Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies
    Stacey D Finley
    Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    BMC Syst Biol 5:193. 2011
    ..The model is applied to investigate the action of VEGF-neutralizing agents (called "anti-VEGF") in the treatment of cancer...
  5. pmc A two-compartment model of VEGF distribution in the mouse
    Phillip Yen
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 6:e27514. 2011
    ..As the VEGF system becomes better characterized in other tissues and cell types, the model can be expanded to include additional compartments and vascular elements...
  6. pmc A systems biology view of blood vessel growth and remodelling
    Elizabeth A Logsdon
    Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
    J Cell Mol Med 18:1491-508. 2014
    ..We describe progress that has been made in applying computational modelling, quantitative biology and high-throughput experimentation to the angiogenesis process. ..