Marcella Ferlito

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes
    Marcella Ferlito
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Mol Cell Cardiol 49:791-800. 2010
  2. ncbi Epigallocatechin gallate inhibits endothelial exocytosis
    Munekazu Yamakuchi
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Biol Chem 389:935-41. 2008
  3. ncbi miR-34a repression of SIRT1 regulates apoptosis
    Munekazu Yamakuchi
    Departments of Medicine and Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:13421-6. 2008
  4. ncbi Nuclear miRNA regulates the mitochondrial genome in the heart
    Samarjit Das
    Department of Pathology, Cardiovascular Division, Johns Hopkins University, Baltimore, MD 21205
    Circ Res 110:1596-603. 2012
  5. ncbi Exocytosis of endothelial cells is regulated by N-ethylmaleimide-sensitive factor
    Munekazu Yamakuchi
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 440:203-15. 2008
  6. ncbi Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    Tsung Cheng Chang
    The McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Mol Cell 26:745-52. 2007
  7. ncbi MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
    Tamia A Harris
    Cellular and Molecular Medicine Program and Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:1516-21. 2008

Collaborators

Detail Information

Publications7

  1. ncbi VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes
    Marcella Ferlito
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Mol Cell Cardiol 49:791-800. 2010
    ..Our data suggest that three specific SNAREs regulate cardiac myocyte exocytosis of ANP. Pathways that modify the exocytic machinery may influence natriuresis and blood pressure...
  2. ncbi Epigallocatechin gallate inhibits endothelial exocytosis
    Munekazu Yamakuchi
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Biol Chem 389:935-41. 2008
    ..NOS inhibition revealed that NO mediates the anti-inflammatory effects of EGCG. Our data suggest that polyphenols can decrease vascular inflammation by increasing the synthesis of NO, which blocks endothelial exocytosis...
  3. ncbi miR-34a repression of SIRT1 regulates apoptosis
    Munekazu Yamakuchi
    Departments of Medicine and Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:13421-6. 2008
    ..Finally, miR-34a itself is a transcriptional target of p53, suggesting a positive feedback loop between p53 and miR-34a. Thus, miR-34a functions as a tumor suppressor, in part, through a SIRT1-p53 pathway...
  4. ncbi Nuclear miRNA regulates the mitochondrial genome in the heart
    Samarjit Das
    Department of Pathology, Cardiovascular Division, Johns Hopkins University, Baltimore, MD 21205
    Circ Res 110:1596-603. 2012
    ..MicroRNAs (miRNAs) are usually 19 to 25 nt long, noncoding RNAs, involved in posttranscriptional gene regulation by binding to the 3'-untranslated regions of target mRNA, which impact on diverse cellular processes...
  5. ncbi Exocytosis of endothelial cells is regulated by N-ethylmaleimide-sensitive factor
    Munekazu Yamakuchi
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 440:203-15. 2008
    ..Further characterization of the factors that regulate exocytosis will lead to novel treatments for vascular diseases such as myocardial infarction and stroke...
  6. ncbi Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    Tsung Cheng Chang
    The McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Mol Cell 26:745-52. 2007
    ..Therefore, it is likely that an important function of miR-34a is the modulation and fine-tuning of the gene expression program initiated by p53...
  7. ncbi MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
    Tamia A Harris
    Cellular and Molecular Medicine Program and Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:1516-21. 2008
    ..These data suggest that microRNA can regulate adhesion molecule expression and may provide additional control of vascular inflammation...