Marcella Ferlito

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes
    Marcella Ferlito
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Mol Cell Cardiol 49:791-800. 2010
  2. pmc Epigallocatechin gallate inhibits endothelial exocytosis
    Munekazu Yamakuchi
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Biol Chem 389:935-41. 2008
  3. pmc H2S Increases Survival during Sepsis: Protective Effect of CHOP Inhibition
    Marcella Ferlito
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205
    J Immunol 192:1806-14. 2014
  4. pmc S-nitrosylation of TRIM72 at cysteine 144 is critical for protection against oxidation-induced protein degradation and cell death
    Mark J Kohr
    Systems Biology Center, National Heart, Lung and Blood Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA Division of Cardiovascular Pathology, Department of Pathology, 720 Rutland Avenue, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA Electronic address
    J Mol Cell Cardiol 69:67-74. 2014
  5. pmc miR-34a repression of SIRT1 regulates apoptosis
    Munekazu Yamakuchi
    Departments of Medicine and Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:13421-6. 2008
  6. pmc Nuclear miRNA regulates the mitochondrial genome in the heart
    Samarjit Das
    Department of Pathology, Cardiovascular Division, Johns Hopkins University, Baltimore, MD 21205
    Circ Res 110:1596-603. 2012
  7. pmc Exocytosis of endothelial cells is regulated by N-ethylmaleimide-sensitive factor
    Munekazu Yamakuchi
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 440:203-15. 2008
  8. pmc Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    Tsung Cheng Chang
    The McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Mol Cell 26:745-52. 2007
  9. pmc MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
    Tamia A Harris
    Cellular and Molecular Medicine Program and Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:1516-21. 2008

Collaborators

Detail Information

Publications9

  1. pmc VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes
    Marcella Ferlito
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    J Mol Cell Cardiol 49:791-800. 2010
    ..Our data suggest that three specific SNAREs regulate cardiac myocyte exocytosis of ANP. Pathways that modify the exocytic machinery may influence natriuresis and blood pressure...
  2. pmc Epigallocatechin gallate inhibits endothelial exocytosis
    Munekazu Yamakuchi
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Biol Chem 389:935-41. 2008
    ..NOS inhibition revealed that NO mediates the anti-inflammatory effects of EGCG. Our data suggest that polyphenols can decrease vascular inflammation by increasing the synthesis of NO, which blocks endothelial exocytosis...
  3. pmc H2S Increases Survival during Sepsis: Protective Effect of CHOP Inhibition
    Marcella Ferlito
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205
    J Immunol 192:1806-14. 2014
    ..The data reveal a major negative role for the transcription factor CHOP in overall survival during sepsis and suggest a new target for clinical intervention, as well potential strategies for treatment. ..
  4. pmc S-nitrosylation of TRIM72 at cysteine 144 is critical for protection against oxidation-induced protein degradation and cell death
    Mark J Kohr
    Systems Biology Center, National Heart, Lung and Blood Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA Division of Cardiovascular Pathology, Department of Pathology, 720 Rutland Avenue, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA Electronic address
    J Mol Cell Cardiol 69:67-74. 2014
    ....
  5. pmc miR-34a repression of SIRT1 regulates apoptosis
    Munekazu Yamakuchi
    Departments of Medicine and Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:13421-6. 2008
    ..Finally, miR-34a itself is a transcriptional target of p53, suggesting a positive feedback loop between p53 and miR-34a. Thus, miR-34a functions as a tumor suppressor, in part, through a SIRT1-p53 pathway...
  6. pmc Nuclear miRNA regulates the mitochondrial genome in the heart
    Samarjit Das
    Department of Pathology, Cardiovascular Division, Johns Hopkins University, Baltimore, MD 21205
    Circ Res 110:1596-603. 2012
    ..MicroRNAs (miRNAs) are usually 19 to 25 nt long, noncoding RNAs, involved in posttranscriptional gene regulation by binding to the 3'-untranslated regions of target mRNA, which impact on diverse cellular processes...
  7. pmc Exocytosis of endothelial cells is regulated by N-ethylmaleimide-sensitive factor
    Munekazu Yamakuchi
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 440:203-15. 2008
    ..Further characterization of the factors that regulate exocytosis will lead to novel treatments for vascular diseases such as myocardial infarction and stroke...
  8. pmc Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    Tsung Cheng Chang
    The McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Mol Cell 26:745-52. 2007
    ..Therefore, it is likely that an important function of miR-34a is the modulation and fine-tuning of the gene expression program initiated by p53...
  9. pmc MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
    Tamia A Harris
    Cellular and Molecular Medicine Program and Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 105:1516-21. 2008
    ..These data suggest that microRNA can regulate adhesion molecule expression and may provide additional control of vascular inflammation...