Jason E Farrar
Affiliation: Johns Hopkins University
- Ribosomal protein gene deletions in Diamond-Blackfan anemiaJason E Farrar
Division of Pediatric Oncology, Department of Oncology, Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Blood 118:6943-51. 2011..These data suggest that ribosomal protein gene deletion is more common than previously suspected and should be considered a component of the initial genetic evaluation in cases of suspected DBA...
- Untangling the phenotypic heterogeneity of Diamond Blackfan anemiaJason E Farrar
Kimmel Comprehensive Cancer Center, Department of Oncology, Division of Pediatric Oncology, Johns Hopkins University, Baltimore, MD 21231, USA
Semin Hematol 48:124-35. 2011..In this review, we summarize the genetic basis of DBA and discuss mechanisms by which the phenotype of DBA might be modified...
- Sensitive quantification of mosaicism using high density SNP arrays and the cumulative distribution functionThomas C Markello
Office of the Clinical Director, NHGRI, National Institutes of Health, Bethesda, MD 20892 1851, USA
Mol Genet Metab 105:665-71. 2012..We also demonstrate application of the method to novel diseases and mechanisms...
- Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemiaJason E Farrar
Division of Pediatric Oncology, Department of Oncology, Kimmel Comprehensive Cancer Center
Blood 112:1582-92. 2008..The results also establish that haploinsufficiency of large ribosomal subunit proteins contributes to bone marrow failure and potentially cancer predisposition...
- WT1 expression at diagnosis does not predict survival in pediatric AML: a report from the Children's Oncology GroupSuzie A Noronha
Division of Pediatric Oncology, Department of Oncology, The Johns Hopkins Hospital, Baltimore, Maryland 21231, USA
Pediatr Blood Cancer 53:1136-9. 2009..Neither overall survival nor event-free survival was correlated with WT1 expression...