Allen Everett

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Hepatoma-derived growth factor binds DNA through the N-terminal PWWP domain
    Jun Yang
    Department of Pediatrics, Division of Pediatric Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA
    BMC Mol Biol 8:101. 2007
  2. doi request reprint Community use of the amplatzer atrial septal defect occluder: results of the multicenter MAGIC atrial septal defect study
    Allen D Everett
    Department of Pediatrics, Johns Hopkins University, School of Medicine, Baltimore, MD 21287, USA
    Pediatr Cardiol 30:240-7. 2009
  3. pmc Mitotic phosphorylation activates hepatoma-derived growth factor as a mitogen
    Allen D Everett
    Department of Pediatrics, Cardiology Division, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
    BMC Cell Biol 12:15. 2011
  4. ncbi request reprint Hepatoma-derived growth factor is a pulmonary endothelial cell-expressed angiogenic factor
    Allen D Everett
    Department of Pediatrics, Cardiovascular Research Center, University of Virginia Health System, Charlottesville, 22908, USA
    Am J Physiol Lung Cell Mol Physiol 286:L1194-201. 2004
  5. ncbi request reprint Development of the MAGIC congenital heart disease catheterization database for interventional outcome studies
    Allen D Everett
    Johns Hopkins University, Baltimore, Maryland 21287, and Children s Hospital of Central California, Madera, USA
    J Interv Cardiol 19:173-7. 2006
  6. pmc Glial fibrillary acidic protein as a brain injury biomarker in children undergoing extracorporeal membrane oxygenation
    Melania M Bembea
    Department of Anesthesiology and Critical Care, Johns Hopkins University, Baltimore, MD, USA mbembea1jhmi edu
    Pediatr Crit Care Med 12:572-9. 2011
  7. pmc Hepatoma-derived growth factor represses SET and MYND domain containing 1 gene expression through interaction with C-terminal binding protein
    Jun Yang
    Department of Pediatrics, Division of Pediatric Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA
    J Mol Biol 386:938-50. 2009
  8. pmc Plasma glial fibrillary acidic protein levels in a child with sickle cell disease and stroke
    William J Savage
    Division of Transfusion Medicine, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
    Acta Haematol 125:103-6. 2011
  9. doi request reprint Biomarkers in pediatrics: children as biomarker orphans
    William J Savage
    Division of Transfusion Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Proteomics Clin Appl 4:915-21. 2010
  10. doi request reprint Intact protein separation by one- and two-dimensional liquid chromatography for the comparative proteomic separation of partitioned serum or plasma
    Simon Sheng
    Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Methods Mol Biol 728:29-46. 2011

Collaborators

Detail Information

Publications26

  1. pmc Hepatoma-derived growth factor binds DNA through the N-terminal PWWP domain
    Jun Yang
    Department of Pediatrics, Division of Pediatric Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA
    BMC Mol Biol 8:101. 2007
    ..In this study, we aimed to identify if HDGF is a DNA binding protein, map the functional DNA binding domain and DNA binding element for HDGF...
  2. doi request reprint Community use of the amplatzer atrial septal defect occluder: results of the multicenter MAGIC atrial septal defect study
    Allen D Everett
    Department of Pediatrics, Johns Hopkins University, School of Medicine, Baltimore, MD 21287, USA
    Pediatr Cardiol 30:240-7. 2009
    ....
  3. pmc Mitotic phosphorylation activates hepatoma-derived growth factor as a mitogen
    Allen D Everett
    Department of Pediatrics, Cardiology Division, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
    BMC Cell Biol 12:15. 2011
    ..Mass spectrometry based methods have identified HDGF as a phosphoprotein without validation or a functional consequence of this post-translational modification...
  4. ncbi request reprint Hepatoma-derived growth factor is a pulmonary endothelial cell-expressed angiogenic factor
    Allen D Everett
    Department of Pediatrics, Cardiovascular Research Center, University of Virginia Health System, Charlottesville, 22908, USA
    Am J Physiol Lung Cell Mol Physiol 286:L1194-201. 2004
    ..We conclude that HDGF is a highly expressed vascular endothelial cell protein in vivo and is a potent endothelial mitogen and regulator of endothelial cell migration by mechanisms distinct from VEGF...
  5. ncbi request reprint Development of the MAGIC congenital heart disease catheterization database for interventional outcome studies
    Allen D Everett
    Johns Hopkins University, Baltimore, Maryland 21287, and Children s Hospital of Central California, Madera, USA
    J Interv Cardiol 19:173-7. 2006
    ....
  6. pmc Glial fibrillary acidic protein as a brain injury biomarker in children undergoing extracorporeal membrane oxygenation
    Melania M Bembea
    Department of Anesthesiology and Critical Care, Johns Hopkins University, Baltimore, MD, USA mbembea1jhmi edu
    Pediatr Crit Care Med 12:572-9. 2011
    ..To determine whether, in children, plasma glial fibrillary acidic protein is associated with brain injury during extracorporeal membrane oxygenation and with mortality...
  7. pmc Hepatoma-derived growth factor represses SET and MYND domain containing 1 gene expression through interaction with C-terminal binding protein
    Jun Yang
    Department of Pediatrics, Division of Pediatric Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA
    J Mol Biol 386:938-50. 2009
    ..Because of moderate conservation of the CtBP binding motif in HDGF family members, trans-repressive activity mediated by CtBP may be a common function among HDGF proteins...
  8. pmc Plasma glial fibrillary acidic protein levels in a child with sickle cell disease and stroke
    William J Savage
    Division of Transfusion Medicine, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA
    Acta Haematol 125:103-6. 2011
    ..Stroke in SCD can occur in the setting of acute illness, and a biomarker that could predict the onset and triage ill children to therapeutic intervention more quickly would be useful...
  9. doi request reprint Biomarkers in pediatrics: children as biomarker orphans
    William J Savage
    Division of Transfusion Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Proteomics Clin Appl 4:915-21. 2010
    ..This review focuses on the fundamentals of biomarkers, the additional considerations needed for applying biomarker research to children, and recommendations for advancing pediatric biomarker research...
  10. doi request reprint Intact protein separation by one- and two-dimensional liquid chromatography for the comparative proteomic separation of partitioned serum or plasma
    Simon Sheng
    Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
    Methods Mol Biol 728:29-46. 2011
    ....
  11. doi request reprint Plasma glial fibrillary acidic protein levels in children with sickle cell disease
    William J Savage
    Divisions of Transfusion Medicine and Pediatric Hematology, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA
    Am J Hematol 86:427-9. 2011
    ..Plasma GFAP is elevated among children with SCD and may be associated with subclinical brain injury...
  12. doi request reprint Can proteomics yield insight into aging aorta?
    Zongming Fu
    Department of Pediatrics, The Johns Hopkins University, Baltimore, MD, USA
    Proteomics Clin Appl 7:477-89. 2013
    ..Such proteins, including milk fat globule-EGF factor 8, matrix metalloproteinase type-2, and vitronectin, could be used as indicators of vascular health, or even explored as therapeutic targets for aging-related vascular diseases. ..
  13. pmc Pre- and post-operative plasma glial fibrillary acidic protein levels in patients with newly diagnosed gliomas
    Hatim Husain
    Brain Cancer Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, Cancer Research Building II, 1550 Orleans Street, 1M 16, Baltimore, MD, 21287, USA
    J Neurooncol 109:123-7. 2012
    ..GFAP remains a potentially informative plasma biomarker for gliomas. Longitudinal studies are required to correlate pGFAP levels with patient outcomes...
  14. pmc High resolution structure of the HDGF PWWP domain: a potential DNA binding domain
    Stephen M Lukasik
    Department of Chemistry, University of Virginia, Charlottesville, VA 22906, USA
    Protein Sci 15:314-23. 2006
    ..Based on the NMR titrations, we propose a model of the interaction of the PWWP domain with DNA...
  15. ncbi request reprint Hemoglobin depletion from plasma: considerations for proteomic discovery in sickle cell disease and other hemolytic processes
    Lisa M Williams
    Department Pediatrics, Division of Pediatric Hematology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proteomics Clin Appl 4:926-30. 2010
    ..The aim of this study was to explore the potential of using nickel-beads for Hb depletion of plasma...
  16. ncbi request reprint Hepatoma-derived growth factor is expressed after vascular injury in the rat and stimulates smooth muscle cell migration
    Jill V Narron
    Department of Pediatrics, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Pediatr Res 59:778-83. 2006
    ..We speculate that HDGF is involved in the SMC proliferative and migratory response to injury resulting in neointimal formation...
  17. ncbi request reprint Hepatoma derived growth factor is a nuclear targeted mitogen
    Allen D Everett
    Department of Pediatrics and the Cardiovascular Research Center, University of Virginia Health System, Charlottesville, Virginia 22908 1356, USA
    Curr Drug Targets 4:367-71. 2003
    ..Because of these roles, HDGF is a potential target for drug design. This review will describe current knowledge about the biochemical functioning of the protein and identify potential avenues for drug development...
  18. pmc Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion
    Zongming Fu
    Laboratory of Cardiovascular Science, National Institute on Aging National Institutes of Health, Baltimore, MD 21224, USA
    Circ Res 104:1337-46. 2009
    ..Thus, targeting of MFG-E8 within this signaling axis pathway is a potential novel therapy for the prevention and treatment of the age-associated vascular diseases such as atherosclerosis...
  19. ncbi request reprint Transgenic expression of protein phosphatase 2A regulatory subunit B56gamma disrupts distal lung differentiation
    Allen D Everett
    Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Am J Physiol Lung Cell Mol Physiol 282:L1266-71. 2002
    ..We propose that B56gamma is expressed at a particular stage of lung development to modulate PP2A action on the Wnt/beta-catenin signaling pathway during lung airway morphogenesis...
  20. ncbi request reprint Juxtamembrane localization of the protein phosphatase-1 inhibitor protein PHI-1 in smooth muscle cells
    Nikolaos A Tountas
    Center for Cell Signaling, University of Virginia School of Medicine, PO Box 800577, Charlottesville, VA 22908, USA
    Histochem Cell Biol 121:343-50. 2004
    ..The common tissue distribution but different cellular localization of PHI-1 and CPI-17 suggest distinctive physiological roles for these two PP1 inhibitors...
  21. ncbi request reprint Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF)
    Maina Lepourcelet
    Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Development 132:415-27. 2005
    ..Our findings also advance understanding of HDGF functions and implicate this developmentally regulated gene in RNA metabolic pathways that may influence malignant behaviors in colorectal cancer...
  22. ncbi request reprint Expression of hepatoma-derived growth factor is a strong prognostic predictor for patients with early-stage non-small-cell lung cancer
    Hening Ren
    Department of Thoracic Head and Neck Medical Oncology, Unit 432, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Clin Oncol 22:3230-7. 2004
    ..We hypothesize that HDGF plays an important role in biologic behavior of early-stage non-small-cell lung cancer (NSCLC)...
  23. ncbi request reprint Hepatoma-derived growth factor induces tumorigenesis in vivo through both direct angiogenic activity and induction of vascular endothelial growth factor
    Yorihide Okuda
    Department of Molecular Medicine, Osaka University Graduate School of Medicine, 2 2 Yamada oka, Suita, Osaka 565 0871
    Cancer Sci 94:1034-41. 2003
    ..Thus, these findings suggested that HDGF-induced tumor formation in vivo involves induction of VEGF as well as direct angiogenic activity...
  24. ncbi request reprint Functional proteomic analysis of melanoma progression
    Karine Bernard
    Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309, USA
    Cancer Res 63:6716-25. 2003
    ..Thus, expression of this antigen likely reports a reduced dependence of protein expression on epidermal interactions...
  25. ncbi request reprint Hepatoma-derived growth factor is highly expressed in developing liver and promotes fetal hepatocyte proliferation
    Hirayuki Enomoto
    Department of Molecular Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
    Hepatology 36:1519-27. 2002
    ..In conclusion, HDGF helps regulate the hepatocyte proliferation in liver development...
  26. pmc The isolation of novel mesenchymal stromal cell chemotactic factors from the conditioned medium of tumor cells
    Siang Yo Lin
    Department of Pharmacology, The Cancer Institute of New Jersey, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08903, USA
    Exp Cell Res 314:3107-17. 2008
    ..Two proteins, cyclophilin B and hepatoma-derived growth factor were then further characterized and shown to promote MSC chemotaxis...

Research Grants9

  1. Hepatoma Derived Growth Factor & VSM Cell Proliferation
    Allen Everett; Fiscal Year: 2005
    ..Indeed, understanding how HDGF regulates cell proliferation may provide additional insights into how growth factors regulate cellular growth in general. ..
  2. Hepatoma derived growth factor and vascular smooth muscle cell proliferation
    Allen Everett; Fiscal Year: 2007
    ..We propose here to determine the mechanism regulating the activity of this protein to provide the basis for the future design of new drugs to treat cardiovascular disease. ..
  3. Hepatoma derived growth factor and vascular smooth muscle cell proliferation
    Allen Everett; Fiscal Year: 2009
    ..We propose here to determine the mechanism regulating the activity of this protein to provide the basis for the future design of new drugs to treat cardiovascular disease. ..
  4. Hepatoma derived growth factor and vascular smooth muscle cell proliferation
    Allen D Everett; Fiscal Year: 2010
    ..We propose here to determine the mechanism regulating the activity of this protein to provide the basis for the future design of new drugs to treat cardiovascular disease. ..