Research Topics
| Ashkan EmadiSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Metabolic and electrochemical mechanisms of dimeric naphthoquinones cytotoxicity in breast cancer cellsAshkan Emadi
Johns Hopkins University, School of Medicine, Department of Internal Medicine, Division of Hematology, 720 Rutland Avenue, Baltimore, MD 21205, USA
Bioorg Med Chem 19:7057-62. 2011..These results also suggest that dimeric naphthoquinones may be used to selectively target cancer cells that depend on oxidative phosphorylation for energy production and macromolecular synthesis...
Hematological manifestations of nephropathic cystinosisAshkan Emadi
Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21231 1000, USA
Acta Haematol 119:169-72. 2008....
Cyclophosphamide and cancer: golden anniversaryAshkan Emadi
Division of Adult Hematology, Johns Hopkins University, Baltimore, MD, USA
Nat Rev Clin Oncol 6:638-47. 2009..We also discuss the development of high-dose cyclophosphamide for BMT and the treatment of autoimmune diseases...
Analytic validity of genetic tests to identify factor V Leiden and prothrombin G20210AAshkan Emadi
Department of Internal Medicine, Johns Hopkins University, Baltimore, MD, USA
Am J Hematol 85:264-70. 2010..There is high-grade evidence that most, but not all, clinical laboratories test for FVL and prothrombin G20210A accurately...
Arsenic trioxide - An old drug rediscoveredAshkan Emadi
Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21231 1000, United States
Blood Rev 24:191-9. 2010..The chemistry, mechanisms of action, and clinical side effects of As(2)O(3) are also discussed...
Diagnosis and management of venous thromboembolism: an update a decade into the new millenniumAshkan Emadi
Division of Hematology, Department of Internal Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Arch Iran Med 14:341-51. 2011..The purpose of the current paper is to review the pathogenesis and epidemiology of venous thromboembolism as well as an evidence-based approach to the diagnosis and management of venous thromboembolism...
Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systematic reviewJodi B Segal
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
JAMA 301:2472-85. 2009..Testing for genetic risks for venous thromboembolism (VTE) is common, but the safety and utility of such testing need review...
Dimeric naphthoquinones, a novel class of compounds with prostate cancer cytotoxicityAshley E Ross
Department of Urology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
BJU Int 108:447-54. 2011..To evaluate the cytotoxicity of dimeric naphthoquinones (BiQs) in prostate cancer cells. • To assess the interaction of dimeric naphthoquinones with common therapies including radiation and docetaxel...
A chemical genetic screen for modulators of asymmetrical 2,2'-dimeric naphthoquinones cytotoxicity in yeastAshkan Emadi
Department of Internal Medicine and Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
PLoS ONE 5:e10846. 2010..In order to gain insight into the mode of action of binaphthoquinones we performed a systematic high-throughput screen in a yeast isogenic deletion mutant array for enhanced or suppressed growth in the presence of binaphthoquinones...
Management of acquired thrombophilic disorders in 2011: focus on heparin-induced thrombocytopenia, antiphospholipid syndrome, myeloproliferative neoplasms and paroxysmal nocturnal hemoglobinuriaAshkan Emadi
Division of Hematology, Department of Internal Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
Arch Iran Med 14:401-11. 2011....
The clinically relevant pharmacogenomic changes in acute myelogenous leukemiaAshkan Emadi
University of Maryland, School of Medicine, Marlene and Stewart Greenebaum Cancer Center, Leukemia and Hematologic Malignancies, Baltimore, MD 21201, USA
Pharmacogenomics 13:1257-69. 2012....
Vitamin and mineral supplements: do we really need them?Farin Kamangar
Department of Public Health Analysis, School of Community Health and Policy, Morgan State University, Baltimore, MD, USA
Int J Prev Med 3:221-6. 2012..Indeed, some studies have shown increased risk of cancers in relation to using certain vitamins...
Ruthenium-based chemotherapeutics: are they ready for prime time?Emmanuel S Antonarakis
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 191, Baltimore, MD 21231, USA
Cancer Chemother Pharmacol 66:1-9. 2010....
