J H Elisseeff

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Biological response of chondrocytes to hydrogels
    J H Elisseeff
    Whitaker Institute of Biomedical Engineering, Department of Biomedical Engineering, Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
    Ann N Y Acad Sci 961:118-22. 2002
  2. ncbi request reprint Photocrosslinkable polysaccharides based on chondroitin sulfate
    Qiang Li
    Department of Biomedical Engineering, Johns Hopkins University, 3400 North Charles Street Clark Hall 106, Baltimore, Maryland 21218, USA
    J Biomed Mater Res A 68:28-33. 2004
  3. ncbi request reprint Embryonic stem cells: potential for more impact
    Jennifer H Elisseeff
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
    Trends Biotechnol 22:155-6. 2004
  4. ncbi request reprint Advances in skeletal tissue engineering with hydrogels
    J Elisseeff
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
    Orthod Craniofac Res 8:150-61. 2005
  5. ncbi request reprint Experimental model for cartilage tissue engineering to regenerate the zonal organization of articular cartilage
    T K Kim
    Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA
    Osteoarthritis Cartilage 11:653-64. 2003
  6. ncbi request reprint Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression
    S Varghese
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA
    Osteoarthritis Cartilage 15:59-68. 2007

Research Grants

Collaborators

  • Jun Wang
  • Qiang Li
  • Funmei Yang
  • Kevin J Yarema
  • S Varghese
  • T K Kim
  • N Hwang
  • P Theprungsirikul
  • S Sahani
  • K J Yarema
  • A Malik
  • E G McFarland
  • B Sharma
  • M A Ruffner
  • C G Williams

Detail Information

Publications6

  1. ncbi request reprint Biological response of chondrocytes to hydrogels
    J H Elisseeff
    Whitaker Institute of Biomedical Engineering, Department of Biomedical Engineering, Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
    Ann N Y Acad Sci 961:118-22. 2002
    ..Further understanding of cell response to scaffolds will allow rational design and development of hydrogels for cartilage tissue engineering...
  2. ncbi request reprint Photocrosslinkable polysaccharides based on chondroitin sulfate
    Qiang Li
    Department of Biomedical Engineering, Johns Hopkins University, 3400 North Charles Street Clark Hall 106, Baltimore, Maryland 21218, USA
    J Biomed Mater Res A 68:28-33. 2004
    ..Chondrocytes remained viable after photoencapsulation and incubation in the biogels, suggesting their possible use for cartilage tissue engineering...
  3. ncbi request reprint Embryonic stem cells: potential for more impact
    Jennifer H Elisseeff
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
    Trends Biotechnol 22:155-6. 2004
  4. ncbi request reprint Advances in skeletal tissue engineering with hydrogels
    J Elisseeff
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
    Orthod Craniofac Res 8:150-61. 2005
    ..The general strategy for tissue engineering includes seeding cells on a biomaterial scaffold. The number of scaffold and cell choices for tissue engineering systems is continually increasing and will be reviewed...
  5. ncbi request reprint Experimental model for cartilage tissue engineering to regenerate the zonal organization of articular cartilage
    T K Kim
    Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA
    Osteoarthritis Cartilage 11:653-64. 2003
    ..Finally, to regenerate the zonal organization, we sought to make multi-layered constructs by encapsulating chondrocytes from different zones of articular cartilage...
  6. ncbi request reprint Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression
    S Varghese
    Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA
    Osteoarthritis Cartilage 15:59-68. 2007
    ..To investigate the effects of glucosamine (GlcN) on chondrocyte proliferation, matrix production, and gene expression for providing insights into the biochemical basis of its reported beneficial effects in osteoarthritis (OA)...

Research Grants13

  1. Synthesis amd Mechanism of Polyglucosamine for Cartilage Tissue Engineering
    Jennifer Elisseeff; Fiscal Year: 2007
    ..1B: Identify specific biochemical pathways responsible for cellular responses to glucosamine. Specific aim 2. Synthesize a polymeric glucosamine for incorporation into 3D scaffolds for cartilage engineering. . ..
  2. Targeted Integration of Tissue Engineered Cartilage
    Jennifer Elisseeff; Fiscal Year: 2004
    ..Tissue integration will be monitored by morphological, biochemical, and mechanical analysis. ..
  3. Tissue Engineering in Congenital Craniofacial Defects
    Jennifer Elisseeff; Fiscal Year: 2009
    ..Normal and mutant mouse cell lines will be used in addition to a clonally-derived mouse mesenchymal stem cell line. Tissue development will be assessed by radiographic and histological analyses. ..
  4. Tissue Engineering in Congenital Craniofacial Defects
    Jennifer Elisseeff; Fiscal Year: 2007
    ..Normal and mutant mouse cell lines will be used in addition to a clonally-derived mouse mesenchymal stem cell line. Tissue development will be assessed by radiographic and histological analyses. ..
  5. Engineering and Integration of Osteochondral Tissue
    Jennifer Elisseeff; Fiscal Year: 2007
    ..Specific aim 3. Chemical attachment of hydrogels to cartilage for improved tissue-implant integration in the joint. ..
  6. Glucosamine and Novel Anolgs for Cartilage Regeneration
    Kevin J Yarema; Fiscal Year: 2010
    ..We propose to develop new methods to treat OA and promote new cartilage formation using novel sugar analogs based on the sugar glucosamine. ..