Research Topics
Species | Robert R EdwardsSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
A clinical genetic method to identify mechanisms by which pain causes depression and anxietyMitchell B Max
Clinical Pain Research Section, Division of Intramural Research, National Institute of Dental and Craniofacial Research, National Institutes of Health, DHHS, Bethesda, MD, USA
Mol Pain 2:14. 2006..We seek molecules that show a significant statistical interaction between (1) the amount of surgical pain relief, and (2) the alleles of the gene, on depression and anxiety during the first postoperative year...
Individual differences in endogenous pain modulation as a risk factor for chronic painRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Neurology 65:437-43. 2005..Long-term cohort studies are necessary to test this hypothesis; such research could yield insight into the nature of chronic pain and permit greater precision in selecting high-risk individuals for chronic pain prevention research...- Ethnic similarities and differences in the chronic pain experience: a comparison of african american, Hispanic, and white patientsRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Pain Med 6:88-98. 2005..However, few studies have evaluated all of these variables, or matched ethnic groups precisely on potential confounds... - Quantitative assessment of experimental pain perception: multiple domains of clinical relevanceRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe St, Meyer 1-101, Baltimore, MD 21287, USA
Pain 114:315-9. 2005 - Pain-related catastrophizing in healthy women is associated with greater temporal summation of and reduced habituation to thermal painRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Clin J Pain 22:730-7. 2006..We assessed, for the first time, catastrophizing's association with the magnitude of temporal summation of pain, a primary marker for central nervous system sensitizability... - Catastrophizing, pain, and social adjustment in scleroderma: relationships with educational levelRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Clin J Pain 22:639-46. 2006..The present study sought to characterize such interrelationships between educational level and pain-related catastrophizing... - Styles of pain coping predict cardiovascular function following a cold pressor testRobert R Edwards
Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 1 101, Baltimore, MD 21287, USA
Pain Res Manag 10:219-22. 2005..While many studies have examined the impact of pain-related coping in adjustment to chronic pain, relatively few have evaluated the physiological consequences of differences in pain-coping styles... - Acute pain at discharge from hospitalization is a prospective predictor of long-term suicidal ideation after burn injuryRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Arch Phys Med Rehabil 88:S36-42. 2007..To determine the extent to which pain contributes to risk for suicidal ideation after burn injury... - Catastrophizing and pain in arthritis, fibromyalgia, and other rheumatic diseasesRobert R Edwards
Dept of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 1 101, Baltimore, MD 21287, USA
Arthritis Rheum 55:325-32. 2006.... - Basal heat pain thresholds predict opioid analgesia in patients with postherpetic neuralgiaRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Anesthesiology 104:1243-8. 2006.... - Symptoms of depression and anxiety as unique predictors of pain-related outcomes following burn injuryRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Ann Behav Med 34:313-22. 2007..However, much of the existing research has relied on global measures of distress that do not separate distinct symptoms of anxiety and depression... - Genetic predictors of acute and chronic painRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 1 108, Baltimore, MD 21287, USA
Curr Rheumatol Rep 8:411-7. 2006.... 
Self-reported pain sensitivity: lack of correlation with pain threshold and toleranceRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Eur J Pain 11:594-8. 2007..These findings suggest that circumventing psychophysical pain testing by assessing individuals' self-reported pain sensitivity is unlikely to be a useful strategy...- Pain tolerance as a predictor of outcome following multidisciplinary treatment for chronic pain: differential effects as a function of sexRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe St, Meyer 218, Baltimore, MD 21287, USA
Pain 106:419-26. 2003..These results indicate that experimental pain responses may be most clinically relevant for women, and that sex differences may exist in the determinants of pain-treatment outcomes... - Individual differences in diffuse noxious inhibitory controls (DNIC): association with clinical variablesRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 1 101, Baltimore, MD 21287, USA
Pain 106:427-37. 2003..These findings highlight the potential clinical relevance of experimental pain procedures and suggest that DNIC may be the laboratory pain response most closely associated with clinical pain and health-related variables... - Pain-related catastrophizing as a risk factor for suicidal ideation in chronic painRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 1 108, Baltimore, MD 21287, USA
Pain 126:272-9. 2006..Further research in this area, including the addition of suicide prevention materials to pain-coping skills training programs, may benefit large numbers of individuals who are at elevated suicide risk as a consequence of chronic pain... - Catastrophizing predicts changes in thermal pain responses after resolution of acute dental painRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD 21287, USA
J Pain 5:164-70. 2004..In the context of clinical pain assessment, it may be important to consider the possibility that descriptions of painful sensations reflect, in part, demographic characteristics... - Symptoms of distress as prospective predictors of pain-related sciatica treatment outcomesRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 1 108, Baltimore, MD 21287, United States
Pain 130:47-55. 2007..Future research should determine whether the prospective identification and treatment of patients with high levels of distress (a "yellow flag") is associated with improved treatment outcomes... - Catastrophizing as a mediator of sex differences in pain: differential effects for daily pain versus laboratory-induced painRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 1 101, Baltimore, MD 21287, USA
Pain 111:335-41. 2004..These findings highlight the role of catastrophizing in shaping pain responses, as well as illuminating potentially important differences between experimental pain assessment and the clinical experience of pain... - Endogenous opioids, blood pressure, and diffuse noxious inhibitory controls: a preliminary studyRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Percept Mot Skills 99:679-87. 2004..This relationship, which did not appear opioid-dependent, supports previous models integrating cardiovascular activity with the functioning of pain-modulatory systems... 
Comparison of patient visits to emergency departments, physician offices, and dental offices for dental problems and injuriesLeonard A Cohen
Department of Health Promotion and Policy, University of Maryland Dental School, Baltimore, MD 21201, USA
J Public Health Dent 71:13-22. 2011..We undertook this study to examine whether there are differences in their use by low-income White and minority adults as compared with higher-income adults...- Toothache pain: a comparison of visits to physicians, emergency departments and dentistsLeonard A Cohen
Department of Health Promotion and Policy, University of Maryland Dental School, Baltimore, MD 21201, USA
J Am Dent Assoc 139:1205-16. 2008..The authors conducted a study to explore their use by low-income and minority adults in comparison with the use of traditional dental services... - Situational versus dispositional measurement of catastrophizing: associations with pain responses in multiple samplesClaudia M Campbell
The Johns Hopkins University School of Medicine, Department of Psychiatry and Behavioral Sciences, Baltimore, MD 21287 7101, USA
J Pain 11:443-453.e2. 2010..Our findings highlight the potential importance of the multidimensional assessment of pain-related catastrophizing, and suggest a role for measuring catastrophizing related to specific, definable events... - Behavioral and socioeconomic correlates of dental problem experience and patterns of health care-seekingLeonard A Cohen
Department of Health Promotion and Policy, University of Maryland Dental School, 650 W Baltimore St, Baltimore, MD 21201, USA
J Am Dent Assoc 142:137-49. 2011..To recognize and better understand barriers to dental care, the authors studied behavioral and socioeconomic factors specific to low-income and minority populations that contribute to patterns of professional health care-seeking... - Catastrophizing and pain-coping in young adults: associations with depressive symptoms and headache painLuis F Buenaver
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Pain 9:311-9. 2008..These data suggest that catastrophizing may require the presence of a pain condition before its detrimental effects are exerted... - Role of pharmacists in consulting with the underserved regarding toothache painLeonard A Cohen
Department of Health Promotion and Policy, University of Maryland Dental School, Baltimore, MD 21201, USA
J Am Pharm Assoc (2003) 49:38-42. 2009..To examine the pharmacist's role in managing toothache pain from the patient's perspective... - The effects of sleep deprivation on pain inhibition and spontaneous pain in womenMichael T Smith
Behavioral Sleep Medicine Program, Johns Hopkins Bayview, Johns Hopkins University School of Medicine, Baltimore MD 21287, USA
Sleep 30:494-505. 2007.... - Low-income and minority patient satisfaction with visits to emergency departments and physician offices for dental problemsLeonard A Cohen
Department of Health Promotion and Policy, The Dental School, University of Maryland, Baltimore, USA
J Am Coll Dent 76:23-31. 2009.... - Self-reported sleep duration associated with distraction analgesia, hyperemia, and secondary hyperalgesia in the heat-capsaicin nociceptive modelClaudia M Campbell
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
Eur J Pain 15:561-7. 2011..The secondary hyperalgesia finding may implicate central involvement, whereas enhanced skin flare response suggests that sleep duration may also impact peripheral inflammatory mechanisms... - Health literacy impact on patient-provider interactions involving the treatment of dental problemsLeonard A Cohen
Department of Health Promotion and Policy, University of Maryland Dental School, Baltimore, MD 21201, USA
J Dent Educ 75:1218-24. 2011..In general, respondents did not express health literacy-related problems. Additional research is needed to identify health literacy-related barriers to effective patient-provider communication... - Pain catastrophizing and salivary cortisol responses to laboratory pain testing in temporomandibular disorder and healthy participantsPhillip J Quartana
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
J Pain 11:186-94. 2010.... - Catastrophizing delays the analgesic effect of distractionClaudia M Campbell
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, USA
Pain 149:202-7. 2010..These results suggest that both distraction and catastrophizing have substantial effects on experimental pain in normal subjects and these variables interact as a function of time... - Pain catastrophizing mediates the relationship between self-reported strenuous exercise involvement and pain ratings: moderating role of anxiety sensitivityBurel R Goodin
Psychology Department, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA
Psychosom Med 71:1018-25. 2009.... - Sleep disorders and their association with laboratory pain sensitivity in temporomandibular joint disorderMichael T Smith
Johns Hopkins University School of Medicine, Department of Psychiatry and Behavioral Sciences, Baltimore, MD, USA
Sleep 32:779-90. 2009..We characterized sleep disorder rates in temporomandibular joint disorder (TMD) and evaluated possible associations between sleep disorders and laboratory measures of pain sensitivity... - Changes in situation-specific pain catastrophizing precede changes in pain report during capsaicin pain: a cross-lagged panel analysis among healthy, pain-free participantsClaudia M Campbell
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Pain 11:876-84. 2010..These results provide initial evidence, in healthy individuals, that changes in catastrophizing may precede changes in pain response... - Altered pain responses in abstinent (±)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") usersUna D McCann
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Room 5B71c, Baltimore, MD 21224, USA
Psychopharmacology (Berl) 217:475-84. 2011..Brain 5-HT neurons play a role in pain modulation, yet little is known about long-term effects of MDMA on pain function. Notably, MDMA users have been shown to have altered sleep, a phenomenon that can lead to altered pain modulation... - Associations between catastrophizing and endogenous pain-inhibitory processes: sex differencesBurel R Goodin
Department of Psychology, University of Maryland, Baltimore County, Baltimore, Maryland 21250, USA
J Pain 10:180-90. 2009..Whether interventions that reduce pain catastrophizing affect pain outcomes via effects on DNIC is in need of investigation... - Evidence for indirect effects of pain catastrophizing on clinical pain among myofascial temporomandibular disorder participants: the mediating role of sleep disturbanceLuis F Buenaver
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Pain 153:1159-66. 2012..These findings have important theoretical and clinical implications. Critically, interventions that reduce pain catastrophizing may concurrently improve sleep and clinical pain... - Coping with toothache pain: a qualitative study of low-income persons and minoritiesLeonard A Cohen
Department of Health Promotion and Policy, University of Maryland Dental School, 650 West Baltimore Street, Baltimore, MD 21201, USA
J Public Health Dent 67:28-35. 2007..This study examined the behavioral impact of toothache pain as well as self-care strategies for pain relief among minority and low-income individuals... - Pain-related catastrophizing and perceived social responses: Inter-relationships in the context of chronic painLuis F Buenaver
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287 7107, USA
Pain 127:234-42. 2007..The study and further understanding of what principal factors mediate catastrophizing's deleterious effects on pain will be important in illuminating the biopsychosocial model of pain... - Duration of sleep contributes to next-day pain report in the general populationRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 1 108, Baltimore, MD 21287, USA
Pain 137:202-7. 2008..1, p=.002, in the structural equation model). Collectively, these findings indicate that night-to-night changes in sleep affect pain report, illuminating the importance of considering sleep when assessing and treating pain... - Age-related differences in endogenous pain modulation: a comparison of diffuse noxious inhibitory controls in healthy older and younger adultsRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 218, Baltimore, MD 21287, USA
Pain 101:155-65. 2003..If replicated, such findings of reduced pain-modulatory capacity in the elderly may partially explain age-related differences in the prevalence, severity, and impact of chronic pain... - Ethnicity, catastrophizing, and qualities of the pain experienceLacy A Fabian
Centers for Public Health Research and Evaluation, Battelle Memorial Institute, Baltimore, Maryland 21209, USA
Pain Med 12:314-21. 2011..The mechanisms that might explain ethnic differences in pain outcomes are unclear, and it remains to be fully established whether the relation between ethnicity and pain response may be indirectly affected by pain catastrophizing... - Individual variation in rapid eye movement sleep is associated with pain perception in healthy women: preliminary dataMichael T Smith
Johns Hopkins University School of Medicine, Behavioral Medicine Research Laboratory and Clinic, 600 North Wolfe Street, Meyer 1 108, Baltimore, MD 21287, USA
Sleep 28:809-12. 2005..Consequently, we sought to evaluate relationships between sleep architecture and laboratory measures of pain processing in healthy women, sleeping under normal conditions... - Suicidal ideation, plans, and attempts in chronic pain patients: factors associated with increased riskMichael T Smith
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 101, Baltimore, MD 21287, USA
Pain 111:201-8. 2004.... - Catastrophizing and experimental pain sensitivity: only in vivo reports of catastrophic cognitions correlate with pain responsesRobert R Edwards
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Pain 6:338-9. 2005 - Age differences in the correlates of physical functioning in patients with chronic painRobert R Edwards
Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Aging Health 18:56-69. 2006..Discussion: These data suggest that the determinants of functioning may vary across the life span, implying a potential for pain management programs tailored to a patient's age... - Polymorphisms in the GTP cyclohydrolase gene (GCH1) are associated with ratings of capsaicin painClaudia M Campbell
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Meyer 1 108, 600 N Wolfe Street, Baltimore, MD 21287, USA
Pain 141:114-8. 2009..When combined, three of the five accounted for a surprisingly high 35% of the inter-individual variance in pain ratings. We conclude that SNPs of the GCH1 gene may profoundly affect the ratings of pain induced by capsaicin... - Pain catastrophizing: a critical reviewPhillip J Quartana
Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Expert Rev Neurother 9:745-58. 2009..We conclude by offering what we believe represents an integrated heuristic model for use by researchers over the next 5 years; a model we believe will advance the field most expediently... - Predictors and consequences of multiple persistent postmastectomy painsIan Kudel
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
J Pain Symptom Manage 34:619-27. 2007.... - Sex-based differences in pain perception and treatmentChanning J Paller
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Pain Med 10:289-99. 2009..We sought to illuminate the complex factors contributing to differences in pain and analgesic responses between males and females, ranging from psychosocial to biological processes... - Mind-body interactions in pain: the neurophysiology of anxious and catastrophic pain-related thoughtsClaudia M Campbell
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Transl Res 153:97-101. 2009..The interface between pain-related neurobiology and processes such as pain-related catastrophizing represents an important avenue for future pain research... - Pain severity in eating disorders predicts longer inpatient hospitalizationJanelle W Coughlin
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Int J Eat Disord 43:737-42. 2010..This study examined pain intensity (PI) in eating disorders... - Psychological screening/phenotyping as predictors for spinal cord stimulationClaudia M Campbell
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Suite 100, Baltimore, MD, 21224, USA
Curr Pain Headache Rep 17:307. 2013..Pain Pract. 6:161-165, 2006). Here, we present a brief overview of recent studies examining these factors in their relationship with SCS outcomes... - Spousal responses are differentially associated with clinical variables in women and men with chronic painRoger B Fillingim
University of Florida College of Dentistry Public Health Services and Research, and North Florida South Georgia VA Health System, Gainesville, Florida 32610, USA
Clin J Pain 19:217-24. 2003..The present study examined pain reports, medication use, psychosocial factors, functional measures, and pain tolerance in patients with chronic pain... - Is self-reported childhood abuse history associated with pain perception among healthy young women and men?Roger B Fillingim
University of Florida College of Dentistry and Gainesville VA Medical Center, Gainesville, FL 32610 0404, USA
Clin J Pain 21:387-97. 2005..The purpose of this study was to examine the association between self-reported history of childhood sexual or physical abuse and experimental pain responses in a nonclinical sample of generally healthy young adults... - Clinical characteristics of chronic back pain as a function of gender and oral opioid useRoger B Fillingim
University of Florida College of Dentistry and North Florida South Georgia VA Health System, Gainesville 32610, USA
Spine (Phila Pa 1976) 28:143-50. 2003..A cross-sectional analysis of data derived from patients with chronic spinal pain undergoing evaluation at a multidisciplinary pain treatment center was conducted... - Mood swings: variability in the use of the Profile of Mood StatesRobert R Edwards
J Pain Symptom Manage 28:534. 2004 - Ethnic differences in responses to multiple experimental pain stimuliClaudia M Campbell
College of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610 0404, USA
Pain 113:20-6. 2005..Hypervigilance partly accounted for group differences. Additional research to determine the mechanisms underlying these effects is warranted... - The laterality of long-term pain following mastectomyRobert R Edwards
J Pain Symptom Manage 31:98-9. 2006 - The role of neuroticism, pain catastrophizing and pain-related fear in vigilance to pain: a structural equations approach. A comment on Goubert et al. (2004)Ian Kudel
Pain 115:214-6; author reply 216-7. 2005 - Re: McCraken et al., A comparison of blacks and whites seeking treatment for chronic pain. Clin J Pain 2001;17:249-55Roger B Fillingim
Clin J Pain 18:136-7. 2002
Research Grants
- Individual Differences in Pain Modulation as Predictors of Post-Surgical PainRobert Edwards; Fiscal Year: 2007....
- Catastrophizing and Pain in Rheumatoid ArthritisRobert Edwards; Fiscal Year: 2007..abstract_text> ..