Richard A E Edden

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. doi request reprint Edited MRS is sensitive to changes in lactate concentration during inspiratory hypoxia
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University, Baltimore, Maryland, USA
    J Magn Reson Imaging 32:320-5. 2010
  2. doi request reprint Reduced GABA concentration in attention-deficit/hyperactivity disorder
    Richard A E Edden
    Division of Neuroradiology, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Arch Gen Psychiatry 69:750-3. 2012
  3. pmc Macromolecule-suppressed GABA-edited magnetic resonance spectroscopy at 3T
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Magn Reson Med 68:657-61. 2012
  4. pmc Spatial and orientational heterogeneity in the statistical sensitivity of skeleton-based analyses of diffusion tensor MR imaging data
    Richard A Edden
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Neurosci Methods 201:213-9. 2011
  5. pmc If J doesn't evolve, it won't J-resolve: J-PRESS with bandwidth-limited refocusing pulses
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University, Baltimore, Maryland 21202, USA
    Magn Reson Med 65:1509-14. 2011
  6. pmc Longitudinal and multi-echo transverse relaxation times of normal breast tissue at 3 Tesla
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, and the Kennedy Krieger Institute, Baltimore, Maryland 21287, USA
    J Magn Reson Imaging 32:982-7. 2010
  7. pmc Measuring T2 in vivo with J-difference editing: application to GABA at 3 Tesla
    Richard A E Edden
    Division of Neuroradiology, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Magn Reson Imaging 35:229-34. 2012
  8. pmc Determining the in vivo transverse relaxation time of GABA in the human brain at 7T
    Jarunee Intrapiromkul
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Magn Reson Imaging 38:1224-9. 2013
  9. pmc Nuclear Overhauser enhancement (NOE) imaging in the human brain at 7T
    Craig K Jones
    Division of MR Research, Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neuroimage 77:114-24. 2013
  10. pmc Reproducibility of brain spectroscopy at 7T using conventional localization and spectral editing techniques
    S Andrea Wijtenburg
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Magn Reson Imaging 38:460-7. 2013

Detail Information

Publications23

  1. doi request reprint Edited MRS is sensitive to changes in lactate concentration during inspiratory hypoxia
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University, Baltimore, Maryland, USA
    J Magn Reson Imaging 32:320-5. 2010
    ....
  2. doi request reprint Reduced GABA concentration in attention-deficit/hyperactivity disorder
    Richard A E Edden
    Division of Neuroradiology, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Arch Gen Psychiatry 69:750-3. 2012
    ..Recent evidence also suggests a deficit in cortical inhibition via the GABA (γ-aminobutyric acid)-ergic system...
  3. pmc Macromolecule-suppressed GABA-edited magnetic resonance spectroscopy at 3T
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Magn Reson Med 68:657-61. 2012
    ..The method is applied to acquire macromolecule-suppressed GABA-edited spectra in 10 healthy participants...
  4. pmc Spatial and orientational heterogeneity in the statistical sensitivity of skeleton-based analyses of diffusion tensor MR imaging data
    Richard A Edden
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Neurosci Methods 201:213-9. 2011
    ..For a uniform (DC) offset between two groups, the skeleton projection-based approaches will be most likely to reveal a difference in centrally located white matter structures oriented obliquely to the imaging matrix...
  5. pmc If J doesn't evolve, it won't J-resolve: J-PRESS with bandwidth-limited refocusing pulses
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University, Baltimore, Maryland 21202, USA
    Magn Reson Med 65:1509-14. 2011
    ..It is also demonstrated that increasing the bandwidth of refocusing pulses significantly reduces the size of such signals...
  6. pmc Longitudinal and multi-echo transverse relaxation times of normal breast tissue at 3 Tesla
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, and the Kennedy Krieger Institute, Baltimore, Maryland 21287, USA
    J Magn Reson Imaging 32:982-7. 2010
    ..To measure longitudinal (T(1)) and multi-echo transverse (T(2)) relaxation times of healthy breast tissue at 3 Tesla (T)...
  7. pmc Measuring T2 in vivo with J-difference editing: application to GABA at 3 Tesla
    Richard A E Edden
    Division of Neuroradiology, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Magn Reson Imaging 35:229-34. 2012
    ....
  8. pmc Determining the in vivo transverse relaxation time of GABA in the human brain at 7T
    Jarunee Intrapiromkul
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Magn Reson Imaging 38:1224-9. 2013
    ..To measure in vivo transverse relaxation times (T2 ) of gamma-aminobutyric acid (GABA) at 7T using the experimental spectral-editing method...
  9. pmc Nuclear Overhauser enhancement (NOE) imaging in the human brain at 7T
    Craig K Jones
    Division of MR Research, Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Neuroimage 77:114-24. 2013
    ....
  10. pmc Reproducibility of brain spectroscopy at 7T using conventional localization and spectral editing techniques
    S Andrea Wijtenburg
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Magn Reson Imaging 38:460-7. 2013
    ..To evaluate the reproducibility of spectroscopic measurements from the anterior cingulate (AC) and the dorsolateral prefrontal cortex (DLPFC) regions at 7T using a 32-channel head coil...
  11. ncbi request reprint In vivo differentiation of N-acetyl aspartyl glutamate from N-acetyl aspartate at 3 Tesla
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Magn Reson Med 57:977-82. 2007
    ..White matter concentrations of NAA (6.7 +/- 0.3 mM) and NAAG (2.2 +/- 0.3 mM) were measured in 10 healthy volunteers to demonstrate the method...
  12. pmc Measuring the longitudinal relaxation time of GABA in vivo at 3 Tesla
    Nicolaas A J Puts
    Russel H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Magn Reson Imaging 37:999-1003. 2013
    ..To measure the in vivo longitudinal relaxation time T1 of GABA at 3 Tesla (T)...
  13. pmc High resolution spectroscopic imaging of GABA at 3 Tesla
    He Zhu
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Magn Reson Med 65:603-9. 2011
    ..5×GM+3.2)×10(-5), R=0.27), with higher γ-aminobutyric acid+ levels in gray matter compared with white. In conclusion, high signal-to-noise ratio γ-aminobutyric acid-MRSI is possible at 3 T within clinically feasible scan times...
  14. ncbi request reprint Impaired tactile processing in children with autism spectrum disorder
    Nicolaas A J Puts
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland
    J Neurophysiol 111:1803-11. 2014
    ..Understanding the specific mechanisms underlying sensory symptoms in autism may allow for more specific therapeutic or drug targeting in the near future. ..
  15. pmc GABA predicts inhibition of frequency-specific oscillations in schizophrenia
    Laura M Rowland
    Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA
    J Neuropsychiatry Clin Neurosci 25:83-7. 2013
    ..Results revealed a strong association between GABA levels and gating of the theta-alpha and beta activities in schizophrenia...
  16. ncbi request reprint Spatial effects in the detection of gamma-aminobutyric acid: improved sensitivity at high fields using inner volume saturation
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Magn Reson Med 58:1276-82. 2007
    ..MEGA-PRESS-IVS is then compared to MEGA-PRESS in a phantom and an average signal increase of 24% is demonstrated in five healthy volunteers...
  17. pmc Measurement of T1 and T2 in the cervical spinal cord at 3 tesla
    Seth A Smith
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Magn Reson Med 60:213-9. 2008
    ..Since the spinal cord has rostral-caudal symmetry, we expect these findings to be applicable to the whole cord...
  18. ncbi request reprint A vibrotactile behavioral battery for investigating somatosensory processing in children and adults
    Nicolaas A J Puts
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Neurosci Methods 218:39-47. 2013
    ..g., neurodevelopmental) cohorts to probe different cortical mechanisms. ..
  19. ncbi request reprint Proton MR spectroscopic imaging of the medulla and cervical spinal cord
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Magn Reson Imaging 26:1101-5. 2007
    ..To demonstrate the feasibility of quantitative, one-dimensional proton MR spectroscopic imaging (1D-MRSI) of the upper cervical spine and medulla at 3.0 Tesla...
  20. doi request reprint An imbalance between excitatory and inhibitory neurotransmitters in amyotrophic lateral sclerosis revealed by use of 3-T proton magnetic resonance spectroscopy
    Bradley R Foerster
    Department of Radiology, University of Michigan, Ann Arbor, MI 48109 5030, USA
    JAMA Neurol 70:1009-16. 2013
    ..A lack of neuroinhibitory function may result in unopposed excitotoxic neuronal damage in amyotrophic lateral sclerosis (ALS)...
  21. pmc Brain metabolite alterations and cognitive dysfunction in early Huntington's disease
    Paul G Unschuld
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Mov Disord 27:895-902. 2012
    ....
  22. ncbi request reprint Theoretical and experimental investigation of the VASO contrast mechanism
    Manus J Donahue
    Russell H Morgan Department of Radiology and Radiological Sciences, Division of MR Research, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Magn Reson Med 56:1261-73. 2006
    ..Thus, many competing effects contribute to VASO contrast and care should be taken during interpretation...
  23. ncbi request reprint Optimized detection of lactate at high fields using inner volume saturation
    Richard A E Edden
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Magn Reson Med 56:912-7. 2006
    ..The method should be feasible at magnetic fields above 3 Tesla, and may also be applied to other coupled spin systems in which modulation effects are important...