Research Topics
| A DobsSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Association between sex steroid hormones and hematocrit in a nationally representative sample of menChanning J Paller
Sidney Kimmel Comprehensive Cancer Center and the Department of Epidemiology, Bloomberg School ofPublic Health, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Androl 33:1332-41. 2012..Thus, changes in sex hormone levels with aging may contribute to the increased prevalence of anemia and thromboembolic stroke in men as they age...- A novel testosterone 2% gel for the treatment of hypogonadal malesAdrian S Dobs
Johns Hopkins University, 1830 Monument St, Suite 328, Baltimore, MD 21287, USA
J Androl 33:601-7. 2012..Patients may find this a suitable option for TRT because of its application site and low volume... 
Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavirAdriana S A Andrade
Division of Infectious Diseases, The Johns Hopkins University, Baltimore, MD 21287, USA
BMC Complement Altern Med 8:50. 2008..We evaluated potential pharmacokinetic interactions between IDV and AG, and assessed whether AG improves IDV-induced insulin resistance...
Role of testosterone in maintaining lean body mass and bone density in HIV-infected patientsA Dobs
Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Int J Impot Res 15:S21-5. 2003..Testosterone may thus make a valuable contribution to the treatment of HIV-infected individuals. International Journal of Impotence Research (2003) 15, Suppl 4, S21-S25. doi:10.1038/sj.ijir.3901032..- Incidence and management of gynecomastia in men treated for prostate cancerAdrian Dobs
Department of Medicine, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 0003, USA
J Urol 174:1737-42. 2005..Gynecomastia is a potentially treatment limiting adverse event in men receiving hormone therapy for prostate cancer... - Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal menC Wang
Divisions of Endocrinology, Department of Medicine, Harbor UCLA Medical Center and Research and Education Institute, Torrance, CA, USA
Clin Endocrinol (Oxf) 54:739-50. 2001..Androgen replacement has been reported to increase bone mineral density (BMD) in hypogonadal men. We studied the effects of 6 months of treatment with a new transdermal testosterone (T) gel preparation on bone turnover markers and BMD... - Vitamin d and its role in cancer and immunity: a prescription for sunlightGerard E Mullin
Integrative GI Nutrition Services, Capsule Endoscopy, Division of Gastroenterology and Liver Disease, Johns Hopkins Hospital, Baltimore, Maryland 21205, USA
Nutr Clin Pract 22:305-22. 2007..Here, we review the role of vitamin D in regulation of the immune system and its possible role in the prevention and treatment of cancer and immune-mediated diseases... - Longitudinal psychomotor speed performance in human immunodeficiency virus-seropositive individuals: impact of age and serostatusNed Sacktor
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Neurovirol 16:335-41. 2010..Mild neurocognitive changes over time among older HIV+ individuals are likely to reflect age associated pathophysiological mechanisms including cerebrovascular risk factors... - Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the atherosclerosis risk in communities studySherita Hill Golden
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Am J Epidemiol 160:540-8. 2004..001). Higher FAI was associated with the hyperinsulinemia and hyperglycemia components of the metabolic syndrome. The role of androgens in glucose homeostasis in postmenopausal women requires further study... - The association of endogenous sex hormones with lipoprotein subfraction profile in the Multi-Ethnic Study of AtherosclerosisDhananjay Vaidya
Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Metabolism 57:782-90. 2008..These findings highlight the potential to improve the lipoprotein profile with sex hormones, but emphasize the intricacies of the interactions... - Association of cigarette smoking, alcohol consumption, and physical activity with sex steroid hormone levels in US menMeredith S Shiels
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Cancer Causes Control 20:877-86. 2009.... - Sex hormone levels and subclinical atherosclerosis in postmenopausal women: the Multi-Ethnic Study of AtherosclerosisPamela Ouyang
Johns Hopkins University, Baltimore, MD 21224, USA
Atherosclerosis 204:255-61. 2009..In contrast, SHBG and testosterone were associated with extent of coronary calcium but in the opposite direction compared to carotid intimal-medial thickness. These differences warrant further evaluation... - Andropause: to treat or not to treat?S Basaria
Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Bayview Medical Center, Baltimore 21224, USA
J Endocrinol Invest 26:693-7. 2003 - Androgens and diabetes in men: results from the Third National Health and Nutrition Examination Survey (NHANES III)Elizabeth Selvin
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Diabetes Care 30:234-8. 2007..The objective of this study is to test the hypothesis that low normal levels of total, free, and bioavailable testosterone are associated with prevalent diabetes in men... - Relationship of sex steroid hormones with bone mineral density (BMD) in a nationally representative sample of menChanning J Paller
Department of Endocrinology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Clin Endocrinol (Oxf) 70:26-34. 2009..We evaluated the association of serum total and free sex steroid hormones and SHBG with osteopaenia in a nationally representative sample of men aged 20-90 years... - Illicit drug use and HIV treatment outcomes in a US cohortJoseph Cofrancesco
Johns Hopkins School of Medicine, Department of Medicine, Baltimore, Maryland, USA
AIDS 22:357-65. 2008..To determine the prevalence of illicit drug use and the impact on HIV treatment... - Drug-induced gynecomastiaAri Eckman
Johns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD 21287, USA
Expert Opin Drug Saf 7:691-702. 2008..When a man is euogonadal, a trial of the anti-estrogen, tamoxifen or an aromatase inhibitor may be an option... - Circulating inflammatory cytokine expression in men with prostate cancer undergoing androgen deprivation therapyMarcello Maggio
Longitudinal Studies Section, Clinical Research Branch and the Laboratory of Immunology, National Institutes of Health, National Institute on Aging, Baltimore, MD, USA
J Androl 27:725-8. 2006..Prospective studies are needed to evaluate for any acute changes in these inflammatory markers that might occur after the initiation of ADT... - Sex steroid hormone concentrations and risk of death in US menAndy Menke
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Epidemiol 171:583-92. 2010..Future studies should be conducted to fully characterize the association of low free and bioavailable testosterone concentrations and mortality in men and to describe the mechanism underlying the association... - Incidence and epidemiology of anal cancer in the multicenter AIDS cohort studyGypsyamber D'Souza
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Acquir Immune Defic Syndr 48:491-9. 2008..To examine the incidence and risk factors for anal cancer in a multicenter cohort of human immunodeficiency virus (HIV) positive and HIV-negative men who have sex with men followed between 1984 and 2006 (Multicenter AIDS Cohort Study)... - Endocrine treatment of transsexual people: a review of treatment regimens, outcomes, and adverse effectsEva Moore
Department of Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
J Clin Endocrinol Metab 88:3467-73. 2003..In light of the complexity of managing treatment goals and adverse effects, the active involvement of a medical doctor experienced in cross-sex hormonal therapy is vital to ensure the safety of transsexual people... - Regional adipose tissue and lipid and lipoprotein levels in HIV-infected womenJudith Currier
Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
J Acquir Immune Defic Syndr 48:35-43. 2008..HIV infection and antiretroviral therapy are associated with dyslipidemia, but the association between regional body fat and lipid levels is not well described... - Prevalence of complementary and alternative medicine use among HIV patients for perceived lipodystrophyMinhee Cho
The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
J Altern Complement Med 12:475-82. 2006..CONCLUSIONS: The rate of CAM use among the HIV-positive population is high and is primarily used to improve general health... - Regional adipose tissue and elevations in serum aminotransferases in HIV-infected individualsPhyllis C Tien
Department of Medicine, University of California, San Francisco, CA 94121, USA
J Acquir Immune Defic Syndr 48:169-76. 2008..Obesity is associated with hepatic steatosis, and ALT is a marker of steatosis in the general population... - Comparison of dual-energy X-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjectsRebecca Scherzer
University of California, San Francisco, CA 94121, USA
Am J Clin Nutr 88:1088-96. 2008.... - Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging-measured adipose tissue depots in both HIV-infected and control subjectsRebecca Scherzer
Northern California Institute for Research and Education, San Francisco, CA, USA
Am J Clin Nutr 87:1809-17. 2008..Studies in persons without HIV infection have compared percentage body fat (%BF) and waist circumference as markers of risk for the complications of excess adiposity, but only limited study has been conducted in HIV-infected subjects... - Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal menChristina Wang
Departments of Medicine Pediatrics, Harbor University of California, Los Angeles Medical Center and Research and Education Institute, Torrance, California 90509, USA
J Clin Endocrinol Metab 89:2085-98. 2004..Thus, monitoring for prostatic disease and assessment for erythrocytosis are strongly advised to reduce the risk of adverse events with T treatment of hypogonadal men... - Oxandrolone in the treatment of HIV-associated weight loss in men: a randomized, double-blind, placebo-controlled studyCarl Grunfeld
University of California San Francisco, and Department of Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
J Acquir Immune Defic Syndr 41:304-14. 2006..To evaluate the efficacy and safety of oxandrolone in promoting body weight and body cell mass (BCM) gain in HIV-associated weight loss... - Serum estrogen, but not testosterone, levels differ between black and white men in a nationally representative sample of AmericansSabine Rohrmann
Division of Cancer Epidemiology, German Cancer Research Center, D 69120 Heidelberg, Germany
J Clin Endocrinol Metab 92:2519-25. 2007..Previous studies comparing hormone levels by race might have been limited by size, restricted age variation, or lack of representation of the general population... - The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected menDavid Wohl
AIDS Clinical Trials Unit, University of North Carolina, Chapel Hill, NC, USA
J Acquir Immune Defic Syndr 48:44-52. 2008..HIV infection and antiretroviral therapy are associated with dyslipidemia, but the association between regional adipose tissue depots and lipid levels is not defined... - Intramuscular testosterone treatment in elderly men: evidence of memory decline and altered brain functionPauline M Maki
Center for Cognitive Medicine, Neuropsychiatric Institute MC 913, University of Illinois at Chicago, 912 South Wood Street, Chicago, Illinois 60612, USA
J Clin Endocrinol Metab 92:4107-14. 2007..Recent clinical trials of im testosterone in eugonadal men suggest positive effects on verbal memory, but other studies find no effect... - Prospective study of attitudinal and relationship predictors of sexual risk in the multicenter AIDS cohort studyDavid G Ostrow
David Ostrow and Associates, Chicago MACS Howard Brown Health Center and Northwestern University School of Medicine, 5455 N Sheridan Rd, Suite 1207, Chicago, IL 60640, USA
AIDS Behav 12:127-38. 2008..We conclude that HIV prevention efforts should target modifiable attitudes (reduced concern about HIV and safer sex fatigue) and increases in sexual risk-taking of MSM, particularly among HIV+ men having sex with serodiscordant partners... - Effect of tuberculosis on the survival of HIV-infected men in a country with low tuberculosis incidenceHugo Lopez-Gatell
Directorate of Epidemiology, Ministry of Health, Mexico, Mexico
AIDS 22:1869-73. 2008..2-4.7). Results underscore the importance of avoiding TB by using preventive interventions such as treatment of latent TB infection, particularly in populations with a large prevalence of HIV/TB co-infected individuals... - Impact of HIV infection and HAART on serum lipids in menSharon A Riddler
University of Pittsburgh, Pittsburgh, PA, USA
JAMA 289:2978-82. 2003.... - Metabolic abnormalities in HIV disease and injection drug useAdrian Dobs
The John Hopkins University School of Medicine, Baltimore, Maryland, USA
J Acquir Immune Defic Syndr 31:S70-7. 2002..The issues covered are current estimations of prevalence, risk factors, underlying pathophysiology, diagnosis, and interventions (prevention and treatment) for metabolic complications of HIV and drug abuse... - Anthropometrics and examiner-reported body habitus abnormalities in the multicenter AIDS cohort studyFrank J Palella
Northwestern University, Feinberg School of Medicine, Div of Infectious Diseases, Chicago, Illinois 60611, USA
Clin Infect Dis 38:903-7. 2004....