A Dobs

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Association between sex steroid hormones and hematocrit in a nationally representative sample of men
    Channing J Paller
    Sidney Kimmel Comprehensive Cancer Center and the Department of Epidemiology, Bloomberg School ofPublic Health, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Androl 33:1332-41. 2012
  2. doi request reprint A novel testosterone 2% gel for the treatment of hypogonadal males
    Adrian S Dobs
    Johns Hopkins University, 1830 Monument St, Suite 328, Baltimore, MD 21287, USA
    J Androl 33:601-7. 2012
  3. pmc Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir
    Adriana S A Andrade
    Division of Infectious Diseases, The Johns Hopkins University, Baltimore, MD 21287, USA
    BMC Complement Altern Med 8:50. 2008
  4. ncbi request reprint Role of testosterone in maintaining lean body mass and bone density in HIV-infected patients
    A Dobs
    Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Int J Impot Res 15:S21-5. 2003
  5. ncbi request reprint Incidence and management of gynecomastia in men treated for prostate cancer
    Adrian Dobs
    Department of Medicine, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 0003, USA
    J Urol 174:1737-42. 2005
  6. ncbi request reprint Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men
    C Wang
    Divisions of Endocrinology, Department of Medicine, Harbor UCLA Medical Center and Research and Education Institute, Torrance, CA, USA
    Clin Endocrinol (Oxf) 54:739-50. 2001
  7. ncbi request reprint Vitamin d and its role in cancer and immunity: a prescription for sunlight
    Gerard E Mullin
    Integrative GI Nutrition Services, Capsule Endoscopy, Division of Gastroenterology and Liver Disease, Johns Hopkins Hospital, Baltimore, Maryland 21205, USA
    Nutr Clin Pract 22:305-22. 2007
  8. pmc Sex hormone levels and subclinical atherosclerosis in postmenopausal women: the Multi-Ethnic Study of Atherosclerosis
    Pamela Ouyang
    Johns Hopkins University, Baltimore, MD 21224, USA
    Atherosclerosis 204:255-61. 2009
  9. doi request reprint The association of endogenous sex hormones with lipoprotein subfraction profile in the Multi-Ethnic Study of Atherosclerosis
    Dhananjay Vaidya
    Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Metabolism 57:782-90. 2008
  10. pmc Longitudinal psychomotor speed performance in human immunodeficiency virus-seropositive individuals: impact of age and serostatus
    Ned Sacktor
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Neurovirol 16:335-41. 2010

Detail Information

Publications37

  1. pmc Association between sex steroid hormones and hematocrit in a nationally representative sample of men
    Channing J Paller
    Sidney Kimmel Comprehensive Cancer Center and the Department of Epidemiology, Bloomberg School ofPublic Health, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Androl 33:1332-41. 2012
    ..Thus, changes in sex hormone levels with aging may contribute to the increased prevalence of anemia and thromboembolic stroke in men as they age...
  2. doi request reprint A novel testosterone 2% gel for the treatment of hypogonadal males
    Adrian S Dobs
    Johns Hopkins University, 1830 Monument St, Suite 328, Baltimore, MD 21287, USA
    J Androl 33:601-7. 2012
    ..Patients may find this a suitable option for TRT because of its application site and low volume...
  3. pmc Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir
    Adriana S A Andrade
    Division of Infectious Diseases, The Johns Hopkins University, Baltimore, MD 21287, USA
    BMC Complement Altern Med 8:50. 2008
    ..We evaluated potential pharmacokinetic interactions between IDV and AG, and assessed whether AG improves IDV-induced insulin resistance...
  4. ncbi request reprint Role of testosterone in maintaining lean body mass and bone density in HIV-infected patients
    A Dobs
    Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Int J Impot Res 15:S21-5. 2003
    ..Testosterone may thus make a valuable contribution to the treatment of HIV-infected individuals. International Journal of Impotence Research (2003) 15, Suppl 4, S21-S25. doi:10.1038/sj.ijir.3901032..
  5. ncbi request reprint Incidence and management of gynecomastia in men treated for prostate cancer
    Adrian Dobs
    Department of Medicine, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 0003, USA
    J Urol 174:1737-42. 2005
    ..Gynecomastia is a potentially treatment limiting adverse event in men receiving hormone therapy for prostate cancer...
  6. ncbi request reprint Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men
    C Wang
    Divisions of Endocrinology, Department of Medicine, Harbor UCLA Medical Center and Research and Education Institute, Torrance, CA, USA
    Clin Endocrinol (Oxf) 54:739-50. 2001
    ..Androgen replacement has been reported to increase bone mineral density (BMD) in hypogonadal men. We studied the effects of 6 months of treatment with a new transdermal testosterone (T) gel preparation on bone turnover markers and BMD...
  7. ncbi request reprint Vitamin d and its role in cancer and immunity: a prescription for sunlight
    Gerard E Mullin
    Integrative GI Nutrition Services, Capsule Endoscopy, Division of Gastroenterology and Liver Disease, Johns Hopkins Hospital, Baltimore, Maryland 21205, USA
    Nutr Clin Pract 22:305-22. 2007
    ..Here, we review the role of vitamin D in regulation of the immune system and its possible role in the prevention and treatment of cancer and immune-mediated diseases...
  8. pmc Sex hormone levels and subclinical atherosclerosis in postmenopausal women: the Multi-Ethnic Study of Atherosclerosis
    Pamela Ouyang
    Johns Hopkins University, Baltimore, MD 21224, USA
    Atherosclerosis 204:255-61. 2009
    ..In contrast, SHBG and testosterone were associated with extent of coronary calcium but in the opposite direction compared to carotid intimal-medial thickness. These differences warrant further evaluation...
  9. doi request reprint The association of endogenous sex hormones with lipoprotein subfraction profile in the Multi-Ethnic Study of Atherosclerosis
    Dhananjay Vaidya
    Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Metabolism 57:782-90. 2008
    ..These findings highlight the potential to improve the lipoprotein profile with sex hormones, but emphasize the intricacies of the interactions...
  10. pmc Longitudinal psychomotor speed performance in human immunodeficiency virus-seropositive individuals: impact of age and serostatus
    Ned Sacktor
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Neurovirol 16:335-41. 2010
    ..Mild neurocognitive changes over time among older HIV+ individuals are likely to reflect age associated pathophysiological mechanisms including cerebrovascular risk factors...
  11. ncbi request reprint Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the atherosclerosis risk in communities study
    Sherita Hill Golden
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am J Epidemiol 160:540-8. 2004
    ..001). Higher FAI was associated with the hyperinsulinemia and hyperglycemia components of the metabolic syndrome. The role of androgens in glucose homeostasis in postmenopausal women requires further study...
  12. pmc Association of cigarette smoking, alcohol consumption, and physical activity with sex steroid hormone levels in US men
    Meredith S Shiels
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Cancer Causes Control 20:877-86. 2009
    ....
  13. pmc Association of baseline sex hormone levels with baseline and longitudinal changes in waist-to-hip ratio: Multi-Ethnic Study of Atherosclerosis
    D Vaidya
    Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Int J Obes (Lond) 36:1578-84. 2012
    ..We analyzed the associations of baseline serum levels of testosterone (T), estradiol (E2), sex-hormone-binding globulin (SHBG) and dehydroepiandrosterone (DHEA) with WHR in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort...
  14. ncbi request reprint Andropause: to treat or not to treat?
    S Basaria
    Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Bayview Medical Center, Baltimore 21224, USA
    J Endocrinol Invest 26:693-7. 2003
  15. pmc Relationship of sex steroid hormones with bone mineral density (BMD) in a nationally representative sample of men
    Channing J Paller
    Department of Endocrinology, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Clin Endocrinol (Oxf) 70:26-34. 2009
    ..We evaluated the association of serum total and free sex steroid hormones and SHBG with osteopaenia in a nationally representative sample of men aged 20-90 years...
  16. pmc Illicit drug use and HIV treatment outcomes in a US cohort
    Joseph Cofrancesco
    Johns Hopkins School of Medicine, Department of Medicine, Baltimore, Maryland, USA
    AIDS 22:357-65. 2008
    ..To determine the prevalence of illicit drug use and the impact on HIV treatment...
  17. ncbi request reprint Androgens and diabetes in men: results from the Third National Health and Nutrition Examination Survey (NHANES III)
    Elizabeth Selvin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
    Diabetes Care 30:234-8. 2007
    ..The objective of this study is to test the hypothesis that low normal levels of total, free, and bioavailable testosterone are associated with prevalent diabetes in men...
  18. ncbi request reprint Circulating inflammatory cytokine expression in men with prostate cancer undergoing androgen deprivation therapy
    Marcello Maggio
    Longitudinal Studies Section, Clinical Research Branch and the Laboratory of Immunology, National Institutes of Health, National Institute on Aging, Baltimore, MD, USA
    J Androl 27:725-8. 2006
    ..Prospective studies are needed to evaluate for any acute changes in these inflammatory markers that might occur after the initiation of ADT...
  19. doi request reprint Sex steroid hormone concentrations and risk of death in US men
    Andy Menke
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 171:583-92. 2010
    ..Future studies should be conducted to fully characterize the association of low free and bioavailable testosterone concentrations and mortality in men and to describe the mechanism underlying the association...
  20. ncbi request reprint Drug-induced gynecomastia
    Ari Eckman
    Johns Hopkins University School of Medicine, 1830 E Monument Street, Baltimore, MD 21287, USA
    Expert Opin Drug Saf 7:691-702. 2008
    ..When a man is euogonadal, a trial of the anti-estrogen, tamoxifen or an aromatase inhibitor may be an option...
  21. doi request reprint Incidence and epidemiology of anal cancer in the multicenter AIDS cohort study
    Gypsyamber D'Souza
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 48:491-9. 2008
    ..To examine the incidence and risk factors for anal cancer in a multicenter cohort of human immunodeficiency virus (HIV) positive and HIV-negative men who have sex with men followed between 1984 and 2006 (Multicenter AIDS Cohort Study)...
  22. pmc Regional adipose tissue and lipid and lipoprotein levels in HIV-infected women
    Judith Currier
    Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
    J Acquir Immune Defic Syndr 48:35-43. 2008
    ..HIV infection and antiretroviral therapy are associated with dyslipidemia, but the association between regional body fat and lipid levels is not well described...
  23. ncbi request reprint Endocrine treatment of transsexual people: a review of treatment regimens, outcomes, and adverse effects
    Eva Moore
    Department of Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    J Clin Endocrinol Metab 88:3467-73. 2003
    ..In light of the complexity of managing treatment goals and adverse effects, the active involvement of a medical doctor experienced in cross-sex hormonal therapy is vital to ensure the safety of transsexual people...
  24. pmc Regional adipose tissue and elevations in serum aminotransferases in HIV-infected individuals
    Phyllis C Tien
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    J Acquir Immune Defic Syndr 48:169-76. 2008
    ..Obesity is associated with hepatic steatosis, and ALT is a marker of steatosis in the general population...
  25. ncbi request reprint Prevalence of complementary and alternative medicine use among HIV patients for perceived lipodystrophy
    Minhee Cho
    The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Altern Complement Med 12:475-82. 2006
    ..Changes in body-fat distribution can occur in some patients on prolonged highly active antiretroviral therapy. Currently, there are fewer effective treatments for the condition. Patients with lipodystrophy may be turning to CAM...
  26. pmc Comparison of dual-energy X-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjects
    Rebecca Scherzer
    University of California, San Francisco, CA 94121, USA
    Am J Clin Nutr 88:1088-96. 2008
    ....
  27. ncbi request reprint Serum estrogen, but not testosterone, levels differ between black and white men in a nationally representative sample of Americans
    Sabine Rohrmann
    Division of Cancer Epidemiology, German Cancer Research Center, D 69120 Heidelberg, Germany
    J Clin Endocrinol Metab 92:2519-25. 2007
    ..Previous studies comparing hormone levels by race might have been limited by size, restricted age variation, or lack of representation of the general population...
  28. ncbi request reprint Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men
    Christina Wang
    Departments of Medicine Pediatrics, Harbor University of California, Los Angeles Medical Center and Research and Education Institute, Torrance, California 90509, USA
    J Clin Endocrinol Metab 89:2085-98. 2004
    ..Thus, monitoring for prostatic disease and assessment for erythrocytosis are strongly advised to reduce the risk of adverse events with T treatment of hypogonadal men...
  29. pmc Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging-measured adipose tissue depots in both HIV-infected and control subjects
    Rebecca Scherzer
    Northern California Institute for Research and Education, San Francisco, CA, USA
    Am J Clin Nutr 87:1809-17. 2008
    ..Studies in persons without HIV infection have compared percentage body fat (%BF) and waist circumference as markers of risk for the complications of excess adiposity, but only limited study has been conducted in HIV-infected subjects...
  30. pmc The associations of regional adipose tissue with lipid and lipoprotein levels in HIV-infected men
    David Wohl
    AIDS Clinical Trials Unit, University of North Carolina, Chapel Hill, NC, USA
    J Acquir Immune Defic Syndr 48:44-52. 2008
    ..HIV infection and antiretroviral therapy are associated with dyslipidemia, but the association between regional adipose tissue depots and lipid levels is not defined...
  31. ncbi request reprint Oxandrolone in the treatment of HIV-associated weight loss in men: a randomized, double-blind, placebo-controlled study
    Carl Grunfeld
    University of California San Francisco, and Department of Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    J Acquir Immune Defic Syndr 41:304-14. 2006
    ..To evaluate the efficacy and safety of oxandrolone in promoting body weight and body cell mass (BCM) gain in HIV-associated weight loss...
  32. ncbi request reprint Metabolic abnormalities in HIV disease and injection drug use
    Adrian Dobs
    The John Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Acquir Immune Defic Syndr 31:S70-7. 2002
    ..The issues covered are current estimations of prevalence, risk factors, underlying pathophysiology, diagnosis, and interventions (prevention and treatment) for metabolic complications of HIV and drug abuse...
  33. ncbi request reprint Prospective study of attitudinal and relationship predictors of sexual risk in the multicenter AIDS cohort study
    David G Ostrow
    David Ostrow and Associates, Chicago MACS Howard Brown Health Center and Northwestern University School of Medicine, 5455 N Sheridan Rd, Suite 1207, Chicago, IL 60640, USA
    AIDS Behav 12:127-38. 2008
    ..We conclude that HIV prevention efforts should target modifiable attitudes (reduced concern about HIV and safer sex fatigue) and increases in sexual risk-taking of MSM, particularly among HIV+ men having sex with serodiscordant partners...
  34. ncbi request reprint Impact of HIV infection and HAART on serum lipids in men
    Sharon A Riddler
    University of Pittsburgh, Pittsburgh, PA, USA
    JAMA 289:2978-82. 2003
    ....
  35. ncbi request reprint Intramuscular testosterone treatment in elderly men: evidence of memory decline and altered brain function
    Pauline M Maki
    Center for Cognitive Medicine, Neuropsychiatric Institute MC 913, University of Illinois at Chicago, 912 South Wood Street, Chicago, Illinois 60612, USA
    J Clin Endocrinol Metab 92:4107-14. 2007
    ..Recent clinical trials of im testosterone in eugonadal men suggest positive effects on verbal memory, but other studies find no effect...
  36. pmc Effect of tuberculosis on the survival of HIV-infected men in a country with low tuberculosis incidence
    Hugo Lopez-Gatell
    Directorate of Epidemiology, Ministry of Health, Mexico, Mexico
    AIDS 22:1869-73. 2008
    ..2-4.7). Results underscore the importance of avoiding TB by using preventive interventions such as treatment of latent TB infection, particularly in populations with a large prevalence of HIV/TB co-infected individuals...
  37. ncbi request reprint Anthropometrics and examiner-reported body habitus abnormalities in the multicenter AIDS cohort study
    Frank J Palella
    Northwestern University, Feinberg School of Medicine, Div of Infectious Diseases, Chicago, Illinois 60611, USA
    Clin Infect Dis 38:903-7. 2004
    ....