Sara A DiVall
Affiliation: Johns Hopkins University
- The influence of endocrine disruptors on growth and development of childrenSara A DiVall
Department of Pediatrics, Division of Endocrinology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Curr Opin Endocrinol Diabetes Obes 20:50-5. 2013..This review describes the most recent data about the effects of endocrine disrupting compounds (EDCs) on infant and early childhood growth and reproductive tract development as well as controversies in the field...
- Egr-1 binds the GnRH promoter to mediate the increase in gene expression by insulinSara A DiVall
Division of Endocrinology, Department of Pediatrics, Johns Hopkins University, 600 N Wolfe Street, Park 211, Baltimore, MD 21287, United States
Mol Cell Endocrinol 270:64-72. 2007..Thus, Egr-1 binds the GnRH promoter at a site between -67 and -76bp from the transcriptional start site to mediate the insulin-induced increase in GnRH gene transcription...
- Endocrinology of female pubertySara A DiVall
Division of Pediatric Endocrinology, Johns Hopkins University, Baltimore, Maryland 21287, USA
Curr Opin Endocrinol Diabetes Obes 16:1-4. 2009....
- Divergent roles of growth factors in the GnRH regulation of puberty in miceSara A DiVall
Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland 21212, USA
J Clin Invest 120:2900-9. 2010..These studies define the role of IGF-1R signaling in the coordination of somatic development with reproductive maturation and provide insight into the mechanisms regulating pubertal timing in anabolic states...
- Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptorKathryn J Brothers
Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Cell Metab 12:295-305. 2010....
- Impaired estrogen feedback and infertility in female mice with pituitary-specific deletion of estrogen receptor alpha (ESR1)Surya P Singh
Divisions of Pediatric Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Biol Reprod 81:488-96. 2009....
- Pubertal development and menarcheSara A DiVall
Division of Endocrinology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Ann N Y Acad Sci 1135:19-28. 2008..A multidisciplinary focus is required to elucidate the complex mechanisms involved in the initiation and progression of puberty...
- Insulin regulation of GnRH gene expression through MAP kinase signaling pathwaysHelen H Kim
University of Chicago, Department of Obstetrics and Gynecology, 5839 South Maryland Avenue MC5053, Chicago, IL 60637, USA
Mol Cell Endocrinol 242:42-9. 2005..Our studies suggest that insulin may regulate reproductive function by direct effects on the GnRH neurons and specifically by stimulating GnRH gene expression...
- The Role of Egr-1 in GnRH NeuronsSara DiVall; Fiscal Year: 2005..Protein-DNA binding studies will be performed on candidate regions of the GnRH promoter. This could define a link between nutritional status and reproductive competency at a molecular level. ..