Research Topics
| Megan J DaileySummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Nutrient specific feeding and endocrine effects of jejunal infusionsMegan J Dailey
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Obesity (Silver Spring) 18:904-10. 2010..Thus, particular nutrients are more effective at producing decreases in food intake, body weight, and inducing changes in peptide levels and could lead to a novel therapy for obesity...
Inositol polyphosphate multikinase: an emerging player for the central action of AMP-activated protein kinaseMegan J Dailey
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Biochem Biophys Res Commun 421:1-3. 2012..Here we review and discuss a novel role for the hypothalamic IPMK signaling in the control of AMPK and central energy homeostasis...
Jejunal linoleic acid infusions require GLP-1 receptor signaling to inhibit food intake: implications for the effectiveness of Roux-en-Y gastric bypassMegan J Dailey
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Am J Physiol Endocrinol Metab 301:E1184-90. 2011..Whether increased secretion of additional gut peptides is also necessary for such suppressions remains to be determined...
Disassociation between preprandial gut peptide release and food-anticipatory activityMegan J Dailey
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross 618, Baltimore, Maryland 21205, USA
Endocrinology 153:132-42. 2012..These data suggest that separate mechanisms may underlie the preprandial increases in ghrelin and GLP-1 and changes in FAA, insulin, and glucose...
Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gainAnutosh Chakraborty
The Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Cell 143:897-910. 2010..IP6K1 knockout mice manifest insulin sensitivity and are resistant to obesity elicited by high-fat diet or aging. Inhibition of IP6K1 may afford a therapeutic approach to obesity and diabetes...
Minireview: Gut peptides: targets for antiobesity drug development?Timothy H Moran
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Endocrinology 150:2526-30. 2009..Whether any individual approach will have significant long-term efficacy remains to be demonstrated. Approaches that target multiple systems may hold the most promise...
Intestinal feedback signaling and satietyTimothy H Moran
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Ross 618, 720 Rutland Ave, Baltimore, MD 21205, United States
Physiol Behav 105:77-81. 2011..Thus, gut peptides are clear targets for future obesity therapeutic developments...
Glucagon-like peptide 1 and appetiteMegan J Dailey
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Trends Endocrinol Metab 24:85-91. 2013..Understanding the mechanisms underlying the appetite-suppressive effects of GLP-1 may help in developing targeted treatments for obesity...
