Research Topics
| N E CroneSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Detail Information
Publications
Functional mapping of human sensorimotor cortex with electrocorticographic spectral analysis. I. Alpha and beta event-related desynchronizationN E Crone
Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Brain 121:2271-99. 1998..We conjecture that alpha ERD may reflect activity within a broad synaptic network with distributed cortical representations...- Multimodal functional mapping of sensorimotor cortex prior to resection of an epileptogenic perirolandic lesionHeidi E Kirsch
Department of Neurology, University of California San Francisco School of Medicine, San Francisco, CA, USA
Epilepsy Behav 5:407-10. 2004..Newer methods such as electrocorticographic spectral analysis may complement traditional electrical cortical stimulation mapping... - High-frequency gamma oscillations and human brain mapping with electrocorticographyNathan E Crone
Department of Neurology, The Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 2 147, Baltimore, MD 21287, USA
Prog Brain Res 159:275-95. 2006.... - Functional mapping of human sensorimotor cortex with electrocorticographic spectral analysis. II. Event-related synchronization in the gamma bandN E Crone
Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Brain 121:2301-15. 1998..In addition, gamma ERS may provide complementary information about cortical neurophysiology that is useful for mapping brain function in humans... - Induced electrocorticographic gamma activity during auditory perception. Brazier Award-winning article, 2001N E Crone
Department of Neurology, The Johns Hopkins University School of Medicine, N Wolfe St, Meyer Building, Baltimore, MD 21287 7247, USA
Clin Neurophysiol 112:565-82. 2001..To define the spatial, temporal, and functional characteristics of induced gamma (>30 Hz) activity during functional activation of the left superior temporal gyrus... - Electrocorticographic gamma activity during word production in spoken and sign languageN E Crone
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Neurology 57:2045-53. 2001..To investigate the functional-neuroanatomic substrates of word production using signed versus spoken language... 
Cortical γ responses: searching high and lowNathan E Crone
Department of Neurology, The Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 2 147, Baltimore, Maryland 21287, United States
Int J Psychophysiol 79:9-15. 2011....- Reorganisation of cortical motor and language distribution in human brainH W Lee
Department of Neurology, Johns Hopkins Medical Institutions, 2 147, Meyer Building, 600 North Wolfe Street, Baltimore, MD 21287 7247, USA
J Neurol Neurosurg Psychiatry 80:285-90. 2009..It is not clear what other circumstances might result in changes in cortical functional maps... - Amplitudes of laser evoked potential recorded from primary somatosensory, parasylvian and medial frontal cortex are graded with stimulus intensityS Ohara
Department of Neurosurgery, Johns Hopkins Hospital, Meyer Building 8-181, 600 North Wolfe Street, Baltimore, MD 21287-7713, USA
Pain 110:318-28. 2004.... - Analysis of synchrony demonstrates 'pain networks' defined by rapidly switching, task-specific, functional connectivity between pain-related cortical structuresS Ohara
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287, USA
Pain 123:244-53. 2006..These results are the first compelling evidence of pain networks characterized by rapidly switching, task-specific functional connectivity... - Analysis of synchrony demonstrates that the presence of "pain networks" prior to a noxious stimulus can enable the perception of pain in response to that stimulusS Ohara
Department of Neurosurgery, Johns Hopkins Hospital, Meyer Building 8 181, 600 North Wolfe Street, Baltimore, MD 21287 7713, USA
Exp Brain Res 185:353-8. 2008..These results suggest that dynamic changes in the functional connectivity between ACC and other cortical regions enable the perception of pain in response to noxious stimuli... 
Fear conditioning is associated with dynamic directed functional interactions between and within the human amygdala, hippocampus, and frontal lobeC C Liu
Department of Neurosurgery, Johns Hopkins University, Baltimore, MD 21287 7713, USA
Neuroscience 189:359-69. 2011..ERC interactions between and within modules can be either static or change dynamically across intervals or stages of fear conditioning...- Attention to a painful cutaneous laser stimulus modulates electrocorticographic event-related desynchronization in humansS Ohara
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21287-7247, USA
Clin Neurophysiol 115:1641-52. 2004..SIGNIFICANCE: This study suggests that thalamocortical circuits are involved in attentional modulation of pain because of the proposed role of these circuits in the mechanisms of ERD... - Transforming electrocortical mapping data into standardized common spaceE K Ritzl
Department of Neurology, Johns Hopkins University, School of Medicine, Johns Hopkins Epilepsy Center, Baltimore, Maryland 21287, USA
Clin EEG Neurosci 38:132-6. 2007..Results confirm the accuracy of our co-registration method for comparing electrode locations across patients... - Intracranial mapping of auditory perception: event-related responses and electrocortical stimulationA Sinai
Department of Neurology, Johns Hopkins School of Medicine, 600 North Wolfe Street, Meyer 2 147, Baltimore, MD 21287, USA
Clin Neurophysiol 120:140-9. 2009..We compared intracranial recordings of auditory event-related responses with electrocortical stimulation mapping (ESM) to determine their functional relationship... - Painful laser stimuli induce directed functional interactions within and between the human amygdala and hippocampusC C Liu
Department of Neurosurgery, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 2105, USA
Neuroscience 178:208-17. 2011.... - Spatial neglect during electrocortical stimulation mapping in the right hemisphereJonathan T Kleinman
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Epilepsia 48:2365-8. 2007..These results suggest that ESM can help predict spatial processing deficits associated with cortical resection, and may help prevent postoperative impairments following resection in right parietal or temporal regions... - Temporal dynamics of verbal object comprehensionJ Hart
Division of Cognitive Neurology Neuropsychology, The Johns Hopkins University, Baltimore, MD 21218, USA
Proc Natl Acad Sci U S A 95:6498-503. 1998..This variability was found to be a function of the subject's familiarity with the objects... - Transient unilateral hearing loss induced by electrocortical stimulationS R Sinha
Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
Neurology 64:383-5. 2005..Under binaural listening conditions, auditory comprehension was impaired at the same site, whereas word repetition, environmental sound recognition, naming, and spontaneous speech remained intact... - Speech recognition impairments in patients with intractable right temporal lobe epilepsyDana F Boatman
Department of Neurology, John Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Epilepsia 47:1397-401. 2006..To evaluate speech recognition in patients with focal intractable epilepsy and surgical resections in the nondominant (right) hemisphere... - Short-term variations in response distribution to cortical stimulationRonald P Lesser
Department of Neurology, Johns Hopkins Uiversity, Baltimore, MD 21287 7247, USA
Brain 131:1528-39. 2008..If so, interventions such as stimulation might be used to alter spread of epileptogenic activity, accelerate learning or enhance cortical reorganization after brain injury... - High-frequency gamma activity (80-150Hz) is increased in human cortex during selective attentionSupratim Ray
Department of Biomedical Engineering, 253 Krieger Hall, Zanvyl Krieger Mind Brain Institute, The Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
Clin Neurophysiol 119:116-33. 2008..To study the role of gamma oscillations (>30Hz) in selective attention using subdural electrocorticography (ECoG) in humans... - Subdural electrodesRonald P Lesser
Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Clin Neurophysiol 121:1376-92. 2010..We review the indications for these, their uses for localizing epileptogenic regions and for localizing cortical regions supporting movement, sensation, and language... - Electrocorticographic high gamma activity versus electrical cortical stimulation mapping of namingAlon Sinai
Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Brain 128:1556-70. 2005..We discuss the relative merits of these two functional mapping techniques... - Quantitative EEG asymmetry correlates with clinical severity in unilateral Sturge-Weber syndromeLaura A Hatfield
Department of Neurology, Kennedy Krieger Institute, Baltimore, MD 21205, USA
Epilepsia 48:191-5. 2007..SWS results in ischemic brain injury, seizures, and neurologic deficits. We hypothesized that a decrease in quantitative EEG (qEEG) power, on the affected side, correlates with clinical severity in subjects with SWS... - Attention to pain is processed at multiple cortical sites in manShinji Ohara
Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD 21278, USA
Exp Brain Res 156:513-7. 2004..These findings suggest that attention gates both early (N2*) and late (P2**) pain-related input to SI, parasylvian, and MF cortical regions while the later components (LP) are specifically related to attention... - Cutaneous painful laser stimuli evoke responses recorded directly from primary somatosensory cortex in awake humansS Ohara
Departments of Neurosurgery and Neurology, Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21278, USA
J Neurophysiol 91:2734-46. 2004.... - Studies of properties of "Pain Networks" as predictors of targets of stimulation for treatment of painC C Liu
Department of Neurosurgery, Johns Hopkins Hospital Baltimore, MD, USA
Front Integr Neurosci 5:80. 2011..These results in humans may be uniquely useful to design and optimize anatomically based pain therapies, such as stimulation of the S1 or critical sites through transcutaneous magnetic fields or implanted electrodes... - Dynamics of event-related causality in brain electrical activityAnna Korzeniewska
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Hum Brain Mapp 29:1170-92. 2008..The method may be a useful tool for investigating the dynamics of causal interactions between various brain regions during cognitive task performance... - Optimizing parameters for terminating cortical afterdischarges with pulse stimulationGholam K Motamedi
Department of Neurology, The Johns Hopkins University, Baltimore, Maryland, U.S.A
Epilepsia 43:836-46. 2002..0001). CONCLUSIONS: BPS is more likely to terminate ADs at primary electrodes, if given early, if applied to the negative peak of the AD waveform, if AD has a rhythmic pattern, and if AD did not start immediately after LS... - Stimulus type affects Wada memory performanceS Marc Testa
Department of Psychiatry and Behavioral Sciences, Division of Medical Psychology, The Johns Hopkins University School of Medicine, 600 N Wolfe Street, Meyer 218, Baltimore, MD 21287, USA
Epilepsy Behav 13:458-62. 2008.... - Use of quantitative EEG in infants with port-wine birthmark to assess for Sturge-Weber brain involvementJoshua B Ewen
Department of Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD 21205, USA
Clin Neurophysiol 120:1433-40. 2009..The current study looks at the ability of qEEG to differentiate between infants with radiographically demonstrated SWS and those without... - Human ECoG analysis during speech perception using matching pursuit: a comparison between stochastic and dyadic dictionariesSupratim Ray
Biomedical Engineering, Johns Hopkins University, 3400 N Charles Street, 338 Krieger Hall, Room 253, Baltimore, MD 21218, USA
IEEE Trans Biomed Eng 50:1371-3. 2003..5%) to the one generated by the stochastic MP. However, the dyadic MP is computationally much faster than the stochastic MP... - Seizures manifesting as an urge to defecate, with an ictal discharge in the right hemisphereMohamad Z Koubeissi
Epilepsia 46:1330-2. 2005..The ictal electroencephalogram lateralized to the right hemisphere, suggesting that the ictal urge to defecate may lateralize to this side...
Research Grants
- Electrocorticographic studies of human cortical functionNathan E Crone; Fiscal Year: 2010..This research could lead to better methods for mapping brain function in patients undergoing surgical treatment for epilepsy. ..
- Electrocorticographic studies of human cortical functionNathan Crone; Fiscal Year: 2009....
- Electrocorticographic studies of human cortical functionNathan Crone; Fiscal Year: 2004..abstract_text> ..
- Electrocorticographic studies of human cortical functionNITISH VYOMESH THAKOR; Fiscal Year: 2010..This could have a profound long-term impact on the ability of future generations of patients seeking to restore lost upper limb function with a lifelike prosthesis. ..