Research Topics
| SARA ELIZABETH COSGROVESummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Detail Information
Publications
Health and economic outcomes of the emergence of third-generation cephalosporin resistance in Enterobacter speciesSara E Cosgrove
Department of Medicine, The John Hopkins Hospital, 1830 E Monument St, Room 9020, Baltimore, MD 21287, USA
Arch Intern Med 162:185-90. 2002..This study evaluated the clinical and economic impact of the emergence of third-generation cephalosporin-resistant Enterobacter species...- Epidemiology of community-acquired methicillin-resistant Staphylococcus aureus skin infections among healthcare workers in an outpatient clinicCecilia P Johnston
Division of Infectious Diseases, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
Infect Control Hosp Epidemiol 27:1133-6. 2006..Cultures of environmental samples from multiple surfaces in the clinic grew toxin-producing CA-MRSA strains, suggesting fomites may play a role in the transmission of these strains of MRSA... - Outbreak management and implications of a nosocomial norovirus outbreakCecilia P Johnston
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Clin Infect Dis 45:534-40. 2007..We describe a norovirus outbreak and its control in a tertiary care hospital during February-May 2004... 
Evaluation of postprescription review and feedback as a method of promoting rational antimicrobial use: a multicenter interventionSara E Cosgrove
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Infect Control Hosp Epidemiol 33:374-80. 2012..To evaluate the impact of postprescription review of broad-spectrum antimicrobial (study-ABX) agents on rates of antimicrobial use...- Caveat emptor: the role of suboptimal bronchoscope repair practices by a third-party vendor in a pseudo-outbreak of pseudomonas in bronchoalveolar lavage specimensSara E Cosgrove
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Infect Control Hosp Epidemiol 33:224-9. 2012..To describe a pseudo-outbreak associated with loose bronchoscope biopsy ports caused by inadequate bronchoscope repair practices by third-party vendors and to alert healthcare personnel to assess bronchoscope repair practices... 
Clinical outcomes of seasonal influenza and pandemic influenza A (H1N1) in pediatric inpatientsPranita D Tamma
Department of Pediatric Infectious Diseases, The Johns Hopkins Medical Institution, Suite 3150 Baltimore, Maryland 21287, USA
BMC Pediatr 10:72. 2010..Although influenza pandemics have the possibility of resulting in considerable illness, we must not ignore the impact that we can experience annually with SI...- Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremiaMarin L Schweizer
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
BMC Infect Dis 11:279. 2011..The outcome of interest for this study was 30-day in-hospital mortality... - The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital chargesSara E Cosgrove
Division of Infectious Diseases, Johns Hopkins Medical Institutions, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Infect Control Hosp Epidemiol 26:166-74. 2005..To evaluate the impact of methicillin resistance in Staphylococcus aureus on mortality, length of hospitalization, and hospital charges... - Impact of different methods of feedback to clinicians after postprescription antimicrobial review based on the Centers For Disease Control and Prevention's 12 Steps to Prevent Antimicrobial Resistance Among Hospitalized AdultsSara E Cosgrove
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Infect Control Hosp Epidemiol 28:641-6. 2007.... - The relationship between antimicrobial resistance and patient outcomes: mortality, length of hospital stay, and health care costsSara E Cosgrove
Division of Infectious Diseases, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Clin Infect Dis 42:S82-9. 2006..Strategies to prevent nosocomial emergence and spread of antimicrobial-resistant organisms are essential... - Staphylococcus aureus with reduced susceptibility to vancomycinS E Cosgrove
Division of Infectious Disease, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Clin Infect Dis 39:539-45. 2004..Next, we describe the mechanisms of resistance and methods of laboratory detection of the organisms. Finally, we address infection control and management issues associated with isolation of VISA and VRSA... - Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxicSara E Cosgrove
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Clin Infect Dis 48:713-21. 2009..This study evaluated the association between this practice and nephrotoxicity... - Optimizing therapy for methicillin-resistant Staphylococcus aureus bacteremiaSara E Cosgrove
Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, 600 N Wolfe Street, Baltimore, MD 21287, USA
Semin Respir Crit Care Med 28:624-31. 2007..aureus endocarditis is life threatening. Selection of an appropriate antibiotic regimen is also an essential factor for optimal management... - Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysisSara E Cosgrove
Division of Infectious Diseases, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts, USA
Clin Infect Dis 36:53-9. 2003..54-2.42; P<.001); significant heterogeneity was present. We explored the reasons for heterogeneity by means of subgroup analyses. MRSA bacteremia is associated with significantly higher mortality rate than is MSSA bacteremia... - Outcomes with daptomycin versus standard therapy for osteoarticular infections associated with Staphylococcus aureus bacteraemiaT Lalani
Division of Infectious Diseases, Duke Clinical Research Institute, Durham, NC, USA
J Antimicrob Chemother 61:177-82. 2008..To evaluate the clinical characteristics, treatment and outcomes of patients with osteoarticular infections (OAIs) associated with Staphylococcus aureus bacteraemia (SAB)... - Staphylococcus aureus colonization among healthcare workers at a tertiary care hospitalCecilia P Johnston
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USA
Infect Control Hosp Epidemiol 28:1404-7. 2007..aureus (MRSA) was 2%. The incidence of MRSA colonization was extremely low. This study suggests that the risk of MRSA transmission to healthcare workers is low in a hospital where MRSA is endemic... - Multidrug-resistant Acinetobacter infection mortality rate and length of hospitalizationRebecca H Sunenshine
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 13:97-103. 2007..5, 95% CI 1.2-5.4 and OR 4.2, 95% CI 1.5-11.6] respectively). Increased hospitalization associated with MDR Acinetobacter infection emphasizes the need for infection control strategies to prevent cross-transmission in healthcare settings... - Development of evaluation modules for use in hospital disaster drillsMollie W Jenckes
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Disaster Med 2:87-95. 2007.... - Outbreak of multidrug-resistant Serratia marcescens infection in a neonatal intensive care unitLisa L Maragakis
Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Infect Control Hosp Epidemiol 29:418-23. 2008..We report the investigation and control of an outbreak of multidrug-resistant (MDR) S. marcescens infection at an NICU... - Management of methicillin-resistant Staphylococcus aureus bacteremiaSara E Cosgrove
Johns Hopkins University School of Medicine, Baltimore, Maryland and 2Duke University Medical Center, Durham, North Carolina, USA
Clin Infect Dis 46:S386-93. 2008..The increasing prevalence of methicillin-resistant S. aureus (MRSA) infections has created a tremendous demand for effective and safe antimicrobial agents other than the historic anti-MRSA agent vancomycin... - Reduction of catheter-associated bloodstream infections in pediatric patients: experimentation and realityChristopher McKee
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
Pediatr Crit Care Med 9:40-6. 2008..Few data exist on successes at reducing pediatric catheter-associated bloodstream infections (CA-BSI). The objective was to eradicate CA-BSI with a multifaceted pediatric-relevant intervention proven effective in adult patients... - The impact of antimicrobial resistance on health and economic outcomesSara E Cosgrove
Division of Infectious Disease, Johns Hopkins Hospital, Baltimore, MD, USA
Clin Infect Dis 36:1433-7. 2003.... - Management and control strategies for community-associated methicillin-resistant Staphylococcus aureusEdina Avdic
Antibiotic Management Program, The Johns Hopkins Hospital, Department of Pharmacy, Osler 425, 600 North Wolfe Street, Baltimore, MD 21287, USA
Expert Opin Pharmacother 9:1463-79. 2008.... - Improving the assessment of vancomycin-resistant enterococci by routine screeningSusan S Huang
Brigham and Women s Hospital, Channing Laboratory and Department of Infection Control, Harvard Medical School, and Harvard Pilgrim Health Care, Boston, MA 02115, USA
J Infect Dis 195:339-46. 2007..Routine surveillance cultures can substantially improve prevalence and incidence estimates, and assessing the range of improvement across diverse units is important... - Improving methicillin-resistant Staphylococcus aureus surveillance and reporting in intensive care unitsSusan S Huang
Brigham and Women s Hospital, Channing Laboratory and Infection Control Department, Harvard Medical School, and Harvard Pilgrim Health Care, Boston, MA 02115, USA
J Infect Dis 195:330-8. 2007..In addition, many assessments underestimate the incidence of acquisition by including prevalent carriers in the at-risk population... - Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infectionJohn J Engemann
Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Clin Infect Dis 36:592-8. 2003..Methicillin resistance is independently associated with increased mortality and hospital charges among patients with S. aureus SSI... - Health and economic impact of surgical site infections diagnosed after hospital dischargeEli N Perencevich
Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Emerg Infect Dis 9:196-203. 2003..Average total costs during the 8 weeks after discharge were US dollars 5,155 for patients with SSI and US dollars 1,773 for controls (p<0.001)... - Studies of bloodstream infection outcomes: reading between the linesSara E Cosgrove
Infect Control Hosp Epidemiol 24:884-6. 2003 - Quality of care and satisfaction among patients isolated for infection controlStephen G Weber
JAMA 291:421; author reply 421-2. 2004 - Fluoroquinolones protective against cephalosporin resistance in gram-negative nosocomial pathogensMitchell J Schwaber
Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Emerg Infect Dis 10:94-9. 2004.... - Effectiveness of hospital staff mass-casualty incident training methods: a systematic literature reviewEdbert B Hsu
Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Prehosp Disaster Med 19:191-9. 2004..Recently, mass-casualty incident (MCI) preparedness and training has received increasing attention at the hospital level... - An outbreak of multidrug-resistant Acinetobacter baumannii associated with pulsatile lavage wound treatmentLisa L Maragakis
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
JAMA 292:3006-11. 2004..Infection control precautions are not routinely used during the procedure and are not included in pulsatile lavage equipment package labeling... - Cases from the osler medical service at Johns Hopkins UniversitySara E Cosgrove
Am J Med 113:158-60. 2002..Magnetic resonance imaging of the brain demonstrated multiple lesions; the largest was in the right frontal lobe with associated hemorrhage (Figure 3). What is the diagnosis?.. - Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureusVance G Fowler
Duke University Medical Center, Durham, NC 27710, USA
N Engl J Med 355:653-65. 2006..Alternative therapies for Staphylococcus aureus bacteremia and endocarditis are needed... - Increased catheter-related bloodstream infection rates after the introduction of a new mechanical valve intravenous access portLisa L Maragakis
Department of Hospital Epidemiology and Infection Control, The John Hopkins Hospital, Baltimore, Maryland, USA
Infect Control Hosp Epidemiol 27:67-70. 2006..We report a significant increase in catheter-related bloodstream infections after the introduction of a new needle-free positive-pressure mechanical valve intravenous access port at our institution... - A multicenter intervention to prevent catheter-associated bloodstream infectionsDavid K Warren
Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA
Infect Control Hosp Epidemiol 27:662-9. 2006..Education-based interventions can reduce the incidence of catheter-associated bloodstream infection. The generalizability of findings from single-center studies is limited... - Evidence that prevention makes cents: Costs of catheter-associated bloodstream infections in the intensive care unitSara E Cosgrove
Crit Care Med 34:2243-4. 2006 - Influenza vaccination of healthcare workers and vaccine allocation for healthcare workers during vaccine shortagesThomas R Talbot
Department of Medicine, Vanderbilt University School of Medicine, A 2200 Medical Center North, 1161 21st Avenue South, Nashville, TN 37232, USA
Infect Control Hosp Epidemiol 26:882-90. 2005..These recommendations apply to all types of healthcare facilities, including acute care hospitals, long-term-care facilities, and ambulatory care settings... - Raising standards while watching the bottom line: making a business case for infection controlEli N Perencevich
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Infect Control Hosp Epidemiol 28:1121-33. 2007.... - Enhanced identification of postoperative infections among inpatientsDeborah S Yokoe
Brigham and Women s Hospital, Boston, Massachusetts, USA
Emerg Infect Dis 10:1924-30. 2004..This screening method was efficient, readily standardized, and suitable for most hospitals... - Ability of physicians to diagnose and manage illness due to category A bioterrorism agentsSara E Cosgrove
Division of Infectious Disease, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Arch Intern Med 165:2002-6. 2005..001). CONCLUSIONS: Physician diagnosis and management of diseases caused by bioterrorism agents is poor. An online didactic module may improve diagnosis and management of diseases caused by these agents... - Strategies for use of a limited influenza vaccine supplySara E Cosgrove
Johns Hopkins University School of Medicine, Division of Infectious Diseases, Department of Medicine, Baltimore, MD, USA
JAMA 293:229-32. 2005
Research Grants
- Reducing Antimicrobial Use Associated with Ventilator Associated Pneumonia and CaSara Cosgrove; Fiscal Year: 2009..We hypothesize that this approach will enhance appropriate use of antimicrobials for both VAP and CAUTI and improve patient outcomes by reducing the known sequelae of antimicrobial overuse. ..
- Reducing Antimicrobial Use Associated with Ventilator Associated Pneumonia and CaSARA ELIZABETH COSGROVE; Fiscal Year: 2010..We hypothesize that this approach will enhance appropriate use of antimicrobials for both VAP and CAUTI and improve patient outcomes by reducing the known sequelae of antimicrobial overuse. ..