Christian L Coles

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. doi request reprint Mass distribution of azithromycin for trachoma control is associated with increased risk of azithromycin-resistant Streptococcus pneumoniae carriage in young children 6 months after treatment
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Rm W5009, Baltimore, MD 21205, USA
    Clin Infect Dis 56:1519-26. 2013
  2. doi request reprint Mass distribution of azithromycin for trachoma control is associated with short-term reduction in risk of acute lower respiratory infection in young children
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 31:341-6. 2012
  3. pmc Pneumococcal carriage at age 2 months is associated with growth deficits at age 6 months among infants in South India
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Baltimore, MD, USA
    J Nutr 142:1088-94. 2012
  4. ncbi request reprint Nutritional status and diarrheal illness as independent risk factors for alveolar pneumonia
    Christian L Coles
    Pediatric Infectious Disease Unit, Soroka University Medical Center, Beer Sheva, Israel
    Am J Epidemiol 162:999-1007. 2005
  5. pmc Association of mass treatment with azithromycin in trachoma-endemic communities with short-term reduced risk of diarrhea in young children
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Am J Trop Med Hyg 85:691-6. 2011
  6. pmc Newborn vitamin A supplementation does not affect nasopharyngeal carriage of Streptococcus pneumoniae in Bangladeshi infants at age 3 months
    Christian L Coles
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Nutr 141:1907-11. 2011
  7. ncbi request reprint Risk factors for the initial symptomatic giardia infection in a cohort of young Arab-Bedouin children
    C L Coles
    S Daniel Abraham International Center for Health and Nutrition, Ben Gurion University of the Negev, Beer Sheva, Israel
    Ann Trop Paediatr 29:291-300. 2009
  8. pmc Nasopharyngeal carriage of S. pneumoniae among young children in rural Nepal
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Trop Med Int Health 14:1025-33. 2009
  9. ncbi request reprint Infectious etiology modifies the treatment effect of zinc in severe pneumonia
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Clin Nutr 86:397-403. 2007
  10. pmc Zinc modifies the association between nasopharyngeal Streptococcus pneumoniae carriage and risk of acute lower respiratory infection among young children in rural Nepal
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Nutr 138:2462-7. 2008

Research Grants

Detail Information

Publications14

  1. doi request reprint Mass distribution of azithromycin for trachoma control is associated with increased risk of azithromycin-resistant Streptococcus pneumoniae carriage in young children 6 months after treatment
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Rm W5009, Baltimore, MD 21205, USA
    Clin Infect Dis 56:1519-26. 2013
    ..Emerging evidence suggests that the mass distribution of azithromycin for trachoma control (MDA) may increase circulation of macrolide resistance in bacteria associated with severe pediatric infections in treated communities...
  2. doi request reprint Mass distribution of azithromycin for trachoma control is associated with short-term reduction in risk of acute lower respiratory infection in young children
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Pediatr Infect Dis J 31:341-6. 2012
    ..We evaluated the effect of a single mass distribution of azithromycin for trachoma on the risk of acute lower respiratory infection (ALRI) during a 6-month period among young children living in 8 communities in rural Tanzania...
  3. pmc Pneumococcal carriage at age 2 months is associated with growth deficits at age 6 months among infants in South India
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Baltimore, MD, USA
    J Nutr 142:1088-94. 2012
    ..Results suggest that pneumococcal carriage at age 2 mo is an independent risk factor for poor growth in young infants. Future studies need to clarify the role of Spn carriage on growth retardation in low-income countries...
  4. ncbi request reprint Nutritional status and diarrheal illness as independent risk factors for alveolar pneumonia
    Christian L Coles
    Pediatric Infectious Disease Unit, Soroka University Medical Center, Beer Sheva, Israel
    Am J Epidemiol 162:999-1007. 2005
    ..Results suggest that improving antenatal care and the nutritional status of infants may reduce the risk of CAAP in Bedouin children. Furthermore, they suggest that vaccines developed to prevent diarrhea may also lower the risk of CAAP...
  5. pmc Association of mass treatment with azithromycin in trachoma-endemic communities with short-term reduced risk of diarrhea in young children
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Am J Trop Med Hyg 85:691-6. 2011
    ..By the 3-6-month period, diarrhea incidence was comparable between groups. Thus, MDA was associated with a short-term reduction in diarrheal morbidity in children...
  6. pmc Newborn vitamin A supplementation does not affect nasopharyngeal carriage of Streptococcus pneumoniae in Bangladeshi infants at age 3 months
    Christian L Coles
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Nutr 141:1907-11. 2011
    ..78 [(95% CI: 0.58-1.04); P = 0.095], which may imply a modest impact on carriage. If so, then the evidence thus far would suggest that Spn carriage reduction is unlikely to be a primary ancillary benefit of newborn VA supplementation...
  7. ncbi request reprint Risk factors for the initial symptomatic giardia infection in a cohort of young Arab-Bedouin children
    C L Coles
    S Daniel Abraham International Center for Health and Nutrition, Ben Gurion University of the Negev, Beer Sheva, Israel
    Ann Trop Paediatr 29:291-300. 2009
    ..Giardiasis is a common protozoan infection with clinical manifestations in children ranging from asymptomatic carriage to persistent diarrhoea with malabsorption. It can lead to growth and developmental retardation...
  8. pmc Nasopharyngeal carriage of S. pneumoniae among young children in rural Nepal
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Trop Med Int Health 14:1025-33. 2009
    ..To provide epidemiologic data on Streptococcus pneumoniae (Spn) carriage in Nepal...
  9. ncbi request reprint Infectious etiology modifies the treatment effect of zinc in severe pneumonia
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Clin Nutr 86:397-403. 2007
    ..Zinc is undergoing evaluation as an inexpensive therapeutic adjuvant for severe pediatric pneumonia...
  10. pmc Zinc modifies the association between nasopharyngeal Streptococcus pneumoniae carriage and risk of acute lower respiratory infection among young children in rural Nepal
    Christian L Coles
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    J Nutr 138:2462-7. 2008
    ..09; P = 0.006) than in the zinc group (AMOR = 2.77; P = 0.288). These findings suggest that zinc prophylaxis may protect children against ALRI associated with carriage of Spn and that the effect may differ by infectious etiology...
  11. ncbi request reprint Increased carriage of macrolide-resistant fecal E. coli following mass distribution of azithromycin for trachoma control
    Jessica C Seidman
    Department of International Health, Department of Environmental Health and Dana Center for Preventive Ophthalmology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, Kongwa Trachoma Project, Kongwa, United Republic of Tanzania and Biology Department, Morgan State University, Baltimore, MD, USA
    Int J Epidemiol 43:1105-13. 2014
    ..MDA has been associated with reduced trachoma prevalence and short-term reductions in other bacterial infections, but can also lead to increased circulation of macrolide-resistant bacteria...
  12. doi request reprint Exposure to indoor biomass fuel and tobacco smoke and risk of adverse reproductive outcomes, mortality, respiratory morbidity and growth among newborn infants in south India
    James M Tielsch
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Int J Epidemiol 38:1351-63. 2009
    ..We assessed the association between exposure to biomass fuel sources and second-hand tobacco smoke (SHTS) in the home and adverse health outcomes in early infancy in a population in rural south India...
  13. pmc Prevalence of small-for-gestational-age and its mortality risk varies by choice of birth-weight-for-gestation reference population
    Joanne Katz
    Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 9:e92074. 2014
    ..We use data from rural Nepal and South India to compare the prevalence of small-for-gestational-age (SGA) and neonatal mortality risk associated with SGA using different birth-weight-for-gestation reference populations...
  14. ncbi request reprint Efficacy of zinc in the treatment of severe pneumonia in hospitalized children <2 y old
    Anuradha Bose
    Departments of Community Medicine and Child Health, Christian Medical College, Vellore, India
    Am J Clin Nutr 83:1089-96; quiz 1207. 2006
    ..Severe pneumonia remains a leading cause of morbidity and mortality in undernourished young children in developing countries...

Research Grants2