Research Topics
| Christian L ColesSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
Research Grants
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Detail Information
Publications
Mass distribution of azithromycin for trachoma control is associated with short-term reduction in risk of acute lower respiratory infection in young childrenChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Pediatr Infect Dis J 31:341-6. 2012..We evaluated the effect of a single mass distribution of azithromycin for trachoma on the risk of acute lower respiratory infection (ALRI) during a 6-month period among young children living in 8 communities in rural Tanzania...
Pneumococcal carriage at age 2 months is associated with growth deficits at age 6 months among infants in South IndiaChristian L Coles
Department of International Health, Bloomberg School of Public Health, Baltimore, MD, USA
J Nutr 142:1088-94. 2012..Results suggest that pneumococcal carriage at age 2 mo is an independent risk factor for poor growth in young infants. Future studies need to clarify the role of Spn carriage on growth retardation in low-income countries...
Association of mass treatment with azithromycin in trachoma-endemic communities with short-term reduced risk of diarrhea in young childrenChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
Am J Trop Med Hyg 85:691-6. 2011..By the 3-6-month period, diarrhea incidence was comparable between groups. Thus, MDA was associated with a short-term reduction in diarrheal morbidity in children...
Newborn vitamin A supplementation does not affect nasopharyngeal carriage of Streptococcus pneumoniae in Bangladeshi infants at age 3 monthsChristian L Coles
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
J Nutr 141:1907-11. 2011..78 [(95% CI: 0.58-1.04); P = 0.095], which may imply a modest impact on carriage. If so, then the evidence thus far would suggest that Spn carriage reduction is unlikely to be a primary ancillary benefit of newborn VA supplementation...
Risk factors for the initial symptomatic giardia infection in a cohort of young Arab-Bedouin childrenC L Coles
S Daniel Abraham International Center for Health and Nutrition, Ben Gurion University of the Negev, Beer Sheva, Israel
Ann Trop Paediatr 29:291-300. 2009..Giardiasis is a common protozoan infection with clinical manifestations in children ranging from asymptomatic carriage to persistent diarrhoea with malabsorption. It can lead to growth and developmental retardation...
Nutritional status and diarrheal illness as independent risk factors for alveolar pneumoniaChristian L Coles
Pediatric Infectious Disease Unit, Soroka University Medical Center, Beer Sheva, Israel
Am J Epidemiol 162:999-1007. 2005..Results suggest that improving antenatal care and the nutritional status of infants may reduce the risk of CAAP in Bedouin children. Furthermore, they suggest that vaccines developed to prevent diarrhea may also lower the risk of CAAP...
Nasopharyngeal carriage of S. pneumoniae among young children in rural NepalChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Trop Med Int Health 14:1025-33. 2009..To provide epidemiologic data on Streptococcus pneumoniae (Spn) carriage in Nepal...
Infectious etiology modifies the treatment effect of zinc in severe pneumoniaChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Clin Nutr 86:397-403. 2007..Zinc is undergoing evaluation as an inexpensive therapeutic adjuvant for severe pediatric pneumonia...
Zinc modifies the association between nasopharyngeal Streptococcus pneumoniae carriage and risk of acute lower respiratory infection among young children in rural NepalChristian L Coles
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Nutr 138:2462-7. 2008..09; P = 0.006) than in the zinc group (AMOR = 2.77; P = 0.288). These findings suggest that zinc prophylaxis may protect children against ALRI associated with carriage of Spn and that the effect may differ by infectious etiology...
Exposure to indoor biomass fuel and tobacco smoke and risk of adverse reproductive outcomes, mortality, respiratory morbidity and growth among newborn infants in south IndiaJames M Tielsch
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Int J Epidemiol 38:1351-63. 2009..We assessed the association between exposure to biomass fuel sources and second-hand tobacco smoke (SHTS) in the home and adverse health outcomes in early infancy in a population in rural south India...
Efficacy of zinc in the treatment of severe pneumonia in hospitalized children <2 y oldAnuradha Bose
Departments of Community Medicine and Child Health, Christian Medical College, Vellore, India
Am J Clin Nutr 83:1089-96; quiz 1207. 2006..Given the conflicting results, further research in representative settings is required to help clarify the role of zinc in the treatment of severe pneumonia...
Research Grants
- Vitamin A in the treatment of neonatal necrotizing enterocolitisChristian Coles; Fiscal Year: 2007....
