Ashley Cimino-Mathews

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. doi request reprint A subset of malignant phyllodes tumors harbors alterations in the Rb/p16 pathway
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA Electronic address
    Hum Pathol 44:2494-500. 2013
  2. pmc Metastatic triple-negative breast cancers at first relapse have fewer tumor-infiltrating lymphocytes than their matched primary breast tumors: a pilot study
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA Electronic address
    Hum Pathol 44:2055-63. 2013
  3. doi request reprint GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 44:1341-9. 2013
  4. doi request reprint Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 44:959-65. 2013
  5. pmc Androgen receptor expression is usually maintained in initial surgically resected breast cancer metastases but is often lost in end-stage metastases found at autopsy
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 43:1003-11. 2012
  6. doi request reprint Clinicopathologic features of ductal carcinoma in situ in young women with an emphasis on molecular subtype
    Christopher J Vandenbussche
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA Electronic address
    Hum Pathol 44:2487-93. 2013
  7. doi request reprint Detection of human papillomavirus in small cell carcinomas of the anus and rectum
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 36:1087-92. 2012
  8. doi request reprint HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression
    Nilay Shah
    Departments of Oncology, Surgery, and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231 1000, USA
    Cancer Res 73:5449-58. 2013
  9. doi request reprint GATA-3 immunohistochemistry in the differential diagnosis of adenocarcinoma of the urinary bladder
    Carla L Ellis
    Department of Pathology, The Johns Hopkins Hospital and School of Medicine, Baltimore, MD Department of Pathology, The University of Texas Southwestern Medical Center, Dallas, TX
    Am J Surg Pathol 37:1756-60. 2013
  10. pmc MYC gene amplification is often acquired in lethal distant breast cancer metastases of unamplified primary tumors
    Aatur D Singhi
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mod Pathol 25:378-87. 2012

Collaborators

Detail Information

Publications14

  1. doi request reprint A subset of malignant phyllodes tumors harbors alterations in the Rb/p16 pathway
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA Electronic address
    Hum Pathol 44:2494-500. 2013
    ..These and other mechanisms may contribute to the increased proliferation in malignant phyllodes relative to other fibroepithelial neoplasms. ..
  2. pmc Metastatic triple-negative breast cancers at first relapse have fewer tumor-infiltrating lymphocytes than their matched primary breast tumors: a pilot study
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA Electronic address
    Hum Pathol 44:2055-63. 2013
    ..These findings suggest that evaluating the immunologic microenvironment of both PBCs and MBCs may yield important clinical information to guide breast cancer prognosis and therapy. ..
  3. doi request reprint GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 44:1341-9. 2013
    ..Finally, GATA3 labeling may help distinguish metaplastic carcinoma from malignant phyllodes tumors...
  4. doi request reprint Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 44:959-65. 2013
    ..Sox10 expression in the basal-like, unclassified triple-negative, and metaplastic carcinomas types supports the concept that these neoplasms show myoepithelial differentiation...
  5. pmc Androgen receptor expression is usually maintained in initial surgically resected breast cancer metastases but is often lost in end-stage metastases found at autopsy
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Hum Pathol 43:1003-11. 2012
    ..This suggests an opportunity for targeted antiandrogen therapy at an earlier stage of disease progression...
  6. doi request reprint Clinicopathologic features of ductal carcinoma in situ in young women with an emphasis on molecular subtype
    Christopher J Vandenbussche
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA Electronic address
    Hum Pathol 44:2487-93. 2013
    ..A larger series is necessary to confirm the impact that the molecular subtypes of ductal carcinoma in situ in younger patients might have on outcome. ..
  7. doi request reprint Detection of human papillomavirus in small cell carcinomas of the anus and rectum
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 36:1087-92. 2012
    ..High-risk HPV can be detected using in situ hybridization in the majority of anorectal small cell carcinomas, which are uniformly p16 positive by IHC. HPV-targeted therapy could result in better control of these aggressive neoplasms...
  8. doi request reprint HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression
    Nilay Shah
    Departments of Oncology, Surgery, and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231 1000, USA
    Cancer Res 73:5449-58. 2013
    ..Taken together, our results establish a function for HOXB13 in TAM resistance through direct suppression of ERα and they identify the IL-6 pathways as mediator of disease progression and recurrence...
  9. doi request reprint GATA-3 immunohistochemistry in the differential diagnosis of adenocarcinoma of the urinary bladder
    Carla L Ellis
    Department of Pathology, The Johns Hopkins Hospital and School of Medicine, Baltimore, MD Department of Pathology, The University of Texas Southwestern Medical Center, Dallas, TX
    Am J Surg Pathol 37:1756-60. 2013
    ..GATA-3 is rarely positive in bladder adenocarcinomas that lack signet ring features and in SRCs displaying extracellular mucin production...
  10. pmc MYC gene amplification is often acquired in lethal distant breast cancer metastases of unamplified primary tumors
    Aatur D Singhi
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Mod Pathol 25:378-87. 2012
    ..These observations underscore the importance of MYC in breast cancer progression/metastasis, as well as its relevance as a potential therapeutic target in otherwise incurable metastatic disease...
  11. pmc EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasis
    Heather M Moore
    Department of Pathology, University of Michigan, Ann Arbor, MI, USA
    Breast Cancer Res Treat 138:741-52. 2013
    ..Together our findings reveal a new mechanism by which EZH2 functions in breast cancer, and provide direct evidence that EZH2 inhibition reduces breast cancer metastasis in vivo...
  12. doi request reprint Borderline atypical ductal hyperplasia/low-grade ductal carcinoma in situ on breast needle core biopsy should be managed conservatively
    Christopher J Vandenbussche
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD 21231 2410, USA
    Am J Surg Pathol 37:913-23. 2013
    ..In conclusion, our study provides preliminary data that justify a conservative approach to borderline ADH/DCIS lesions on CNB: that is, diagnose as MADH and treat by conservative excision...
  13. doi request reprint A PIK3CA mutation detected in plasma from a patient with synchronous primary breast and lung cancers
    Danijela Jelovac
    The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA
    Hum Pathol 45:880-3. 2014
    ..This case report highlights potential applications and concerns that can arise with the use of ptDNA in clinical oncology practice. ..
  14. doi request reprint Cytologic and histologic findings of iron pill-induced injury of the lower respiratory tract
    Ashley Cimino-Mathews
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland
    Diagn Cytopathol 41:901-3. 2013
    ..The presence of extracellular and intracellular crystalline iron in the airway lumen and/or mucosa with associated varying degrees of ulceration and inflammation confirms the diagnosis...