ELIZABETH HUI CHEN

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Control of myoblast fusion by a guanine nucleotide exchange factor, loner, and its effector ARF6
    Elizabeth H Chen
    Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Dallas, TX 75390, USA
    Cell 114:751-62. 2003
  2. ncbi Unveiling the mechanisms of cell-cell fusion
    Elizabeth H Chen
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 308:369-73. 2005
  3. ncbi Cell-cell fusion
    Elizabeth H Chen
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD 21205, USA
    FEBS Lett 581:2181-93. 2007
  4. ncbi A critical function for the actin cytoskeleton in targeted exocytosis of prefusion vesicles during myoblast fusion
    Sangjoon Kim
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Dev Cell 12:571-86. 2007
  5. ncbi Ultrastructural analysis of myoblast fusion in Drosophila
    Shiliang Zhang
    Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 475:275-97. 2008
  6. ncbi Towards a molecular pathway for myoblast fusion in Drosophila
    Elizabeth H Chen
    Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Dallas, TX 75390, USA
    Trends Cell Biol 14:452-60. 2004

Research Grants

  1. Molecular Mechanisms of Myoblast Fusion
    Elizabeth Chen; Fiscal Year: 2007
  2. Molecular Mechanisms of Myoblast Fusion
    ELIZABETH HUI CHEN; Fiscal Year: 2010

Collaborators

Detail Information

Publications6

  1. ncbi Control of myoblast fusion by a guanine nucleotide exchange factor, loner, and its effector ARF6
    Elizabeth H Chen
    Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Dallas, TX 75390, USA
    Cell 114:751-62. 2003
    ..In muscle cells, this fusigenic mechanism is coupled to fusion receptors; in other fusion-competent cell types it may be triggered by different upstream signals...
  2. ncbi Unveiling the mechanisms of cell-cell fusion
    Elizabeth H Chen
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Science 308:369-73. 2005
    ..We also consider how proteins involved in general aspects of membrane dynamics have been co-opted to control fusion of diverse cell types by coupling with specialized proteins involved in cell-cell recognition, adhesion, and signaling...
  3. ncbi Cell-cell fusion
    Elizabeth H Chen
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, 725 N Wolfe Street, Baltimore, MD 21205, USA
    FEBS Lett 581:2181-93. 2007
    ....
  4. ncbi A critical function for the actin cytoskeleton in targeted exocytosis of prefusion vesicles during myoblast fusion
    Sangjoon Kim
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Dev Cell 12:571-86. 2007
    ..These studies reveal a surprising cell-type specificity of Sltr-mediated actin polymerization in myoblast fusion, and demonstrate that targeted exocytosis of prefusion vesicles is a critical step prior to plasma membrane fusion...
  5. ncbi Ultrastructural analysis of myoblast fusion in Drosophila
    Shiliang Zhang
    Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 475:275-97. 2008
    ..Furthermore, we describe an immunoelectron microscopic method for localizing specific proteins relative to the fusion apparatus...
  6. ncbi Towards a molecular pathway for myoblast fusion in Drosophila
    Elizabeth H Chen
    Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Dallas, TX 75390, USA
    Trends Cell Biol 14:452-60. 2004
    ..In this article, we review these recent advances and discuss how Drosophila offers a powerful model system to study myoblast fusion in vivo...

Research Grants5

  1. Molecular Mechanisms of Myoblast Fusion
    Elizabeth Chen; Fiscal Year: 2007
    ..We will examine its phenotype, localization, and interactions with known fusion proteins as well as with components of the actin cytoskeleton. ..
  2. Molecular Mechanisms of Myoblast Fusion
    ELIZABETH HUI CHEN; Fiscal Year: 2010
    ..We will examine its phenotype, localization, and interactions with known fusion proteins as well as with components of the actin cytoskeleton. ..