Affiliation: Johns Hopkins University
- Sphingolipids in atherosclerosis and vascular biologyS Chatterjee
Lipid Research Atherosclerosis Division, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287 3654, USA
Arterioscler Thromb Vasc Biol 18:1523-33. 1998..The findings described here indicate an important role for sphingolipids in vascular biology and provide an exciting opportunity for further research in vascular disease and atherosclerosis...
- Molecular cloning, characterization, and expression of a novel human neutral sphingomyelinaseS Chatterjee
Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Maryland 21287 3654, USA
J Biol Chem 274:37407-12. 1999..We believe that the molecular cloning and characterization of N-SMase cDNA will accelerate the process to define its role as a key regulator in apoptosis, lipid and lipoprotein metabolism, and other cell regulatory pathways...
- Neutral sphingomyelinase: past, present and futureS Chatterjee
The Johns Hopkins Hospital, Baltimore, MD 21287 3654, USA
Chem Phys Lipids 102:79-96. 1999..The findings reported here suggests that N-SMase plays important cell regulatory roles and provide an exciting opportunity to further these findings to understand the pathophysiology of human disease states...
- Lactosylceramide mediates shear-induced endothelial superoxide production and intercellular adhesion molecule-1 expressionL H Yeh
Vascular Bioengineering Laboratory, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
J Vasc Res 38:551-9. 2001..and O2(-.) mediates the shear-induced increase in ICAM-1 expression. Thus, LacCer may play an important role in hemodynamic force-induced pathological conditions, such as atherosclerosis and ischemia/reperfusion injury...