Research Topics
| Todd BrownSummaryAffiliation: Johns Hopkins University Country: USA Publications
Research Grants
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Detail Information
Publications
Approach to the human immunodeficiency virus-infected patient with lipodystrophyTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins University, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
J Clin Endocrinol Metab 93:2937-45. 2008..The contribution of body fat changes and metabolic abnormalities to cardiovascular risk and the changing risk profiles of newer antiretroviral regimens are under intense investigation...- Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavirAdriana S A Andrade
Division of Infectious Diseases, The Johns Hopkins University, Baltimore, MD 21287, USA
BMC Complement Altern Med 8:50. 2008..We evaluated potential pharmacokinetic interactions between IDV and AG, and assessed whether AG improves IDV-induced insulin resistance... 
Bone turnover, osteoprotegerin/RANKL and inflammation with antiretroviral initiation: tenofovir versus non-tenofovir regimensTodd T Brown
Division of Endocrinology and Metabolism, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
Antivir Ther 16:1063-72. 2011....- Anthropometry in the prediction of sleep disordered breathing in HIV-positive and HIV-negative menTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD, USA
Antivir Ther 15:651-9. 2010.... - Association between initiation of antiretroviral therapy with efavirenz and decreases in 25-hydroxyvitamin DTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore, MD, USA
Antivir Ther 15:425-9. 2010..We aimed to determine whether antiretroviral therapy (ART) initiation with efavirenz (EFV) is associated with decreases in 25-hydroxyvitamin D (25[OH]D) compared with non-EFV regimens... - Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapyTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore, Maryland, USA
Diabetes Care 33:2244-9. 2010..To determine whether systemic inflammation after initiation of HIV-antiretroviral therapy (ART) is associated with the development of diabetes... - Hepatic steatosis associated with increased central body fat by dual-energy X-ray absorptiometry and uncontrolled HIV in HIV/hepatitis C co-infected personsTodd T Brown
Johns Hopkins School of Medicine, USA
AIDS 24:811-7. 2010..To evaluate the relationship between regional body composition and liver disease (fibrosis or steatosis) in HIV/HCV co-infected individuals... - Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic reviewTodd T Brown
Johns Hopkins University, 1830 East Monument Street, Baltimore, MD 21287, USA
AIDS 20:2165-74. 2006..Prevalence estimates of osteopenia and osteoporosis (reduced bone mineral density; BMD) in HIV-infected patients and the role of antiretroviral therapy (ART) varies in the literature... - Longitudinal anthropometric changes in HIV-infected and HIV-uninfected menTodd Brown
Johns Hopkins University, Baltimore, MD 21287, USA
J Acquir Immune Defic Syndr 43:356-62. 2006.... - Statin therapy and changes in hip circumference among HIV-infected participants in the ALLRT CohortTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore, MD, USA
Antivir Ther 14:853-8. 2009..We aimed to determine whether statin exposure in antiretroviral-treated individuals is associated with increases in hip circumference compared with HIV treatment without concomitant statin use... 
The effects of HIV-1 infection on endocrine organsTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore, MD 21287, United States
Best Pract Res Clin Endocrinol Metab 25:403-13. 2011....- Cumulative exposure to nucleoside analogue reverse transcriptase inhibitors is associated with insulin resistance markers in the Multicenter AIDS Cohort StudyTodd T Brown
Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA
AIDS 19:1375-83. 2005..To estimate insulin resistance and its relationship to antiretroviral therapy (ART) in a cohort of HIV-infected persons with comparison to HIV-seronegative controls... - Antiretroviral therapy and the prevalence and incidence of diabetes mellitus in the multicenter AIDS cohort studyTodd T Brown
Department of Medicine, School of Medicine, The Johns Hopkins University, Baltimore, MD, USA
Arch Intern Med 165:1179-84. 2005..The risk of diabetes mellitus (DM) in human immunodeficiency virus (HIV)-infected patients receiving highly active antiretroviral therapy (HAART) has not been well defined... - Management of the metabolic effects of HIV and HIV drugsTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins University, 1830 East Monument Street, Baltimore, MD 21287, USA
Nat Rev Endocrinol 8:11-21. 2012.... - Reduced bone mineral density in human immunodeficiency virus-infected patients and its association with increased central adiposity and postload hyperglycemiaTodd T Brown
Department of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA
J Clin Endocrinol Metab 89:1200-6. 2004..Bone resorption is independently associated with female gender and dyslipidemia. HIV-infected patients with metabolic abnormalities may represent a population that would benefit from bone density screening... - Longitudinal increases in waist circumference are associated with HIV-serostatus, independent of antiretroviral therapyTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins University, 1830 East Monument Street, Baltimore, MD 21287, USA
AIDS 21:1731-8. 2007..The relative contributions of the different classes of antiretroviral therapy (ART), HIV infection per se, and aging to body shape changes in HIV-infected patients have not been clearly defined in longitudinal studies... - Relation of stavudine discontinuation to anthropometric changes among HIV-infected womenPhyllis C Tien
Department of Medicine, University of California, San Francisco Veterans Affairs Medical Center, San Francisco, CA 94121, USA
J Acquir Immune Defic Syndr 44:43-8. 2007..To characterize changes in regional anthropometry associated with stavudine exposure and discontinuation... - Effect of highly active antiretroviral therapy on incident AIDS using calendar period as an instrumental variableLauren E Cain
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Am J Epidemiol 169:1124-32. 2009..These methods may help resolve discrepancies between observational and randomized evidence... - Body composition, gender, and illicit drug use in an urban cohortJoseph Cofrancesco
Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
Am J Drug Alcohol Abuse 33:467-74. 2007..3 vs.19.9 kg, p = .01) and lower body mass index (21.9 vs. 25.1, p = .01) versus less frequent or nonusers. These data suggest a sex difference in body composition associated with drug use... - Opiate drug use: a potential contributor to the endocrine and metabolic complications in human immunodeficiency virus diseaseOdelia B Cooper
Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore, Maryland, USA
Clin Infect Dis 37:S132-6. 2003..Although much of the evidence should be viewed as preliminary, these potential abnormalities should be kept in mind when treating opiate-dependent patients infected with HIV... - Incidence and risk factors for steatosis progression in adults coinfected with HIV and hepatitis C virusTinsay A Woreta
The Johns Hopkins Hospital University School of Medicine, Baltimore, Maryland 21287, USA
Gastroenterology 140:809-17. 2011..We prospectively examined the natural history of steatosis in patients coinfected with HIV and HCV who attended an urban HIV clinic... - Management options for facial lipoatrophyJoseph Cofrancesco
Johns Hopkins Lipodystrophy and Metabolic Complications Clinic, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
AIDS Read 14:639-40, 645-50. 2004..Prevention and early recognition of lipoatrophy and proper selection or early modification of antiretroviral treatment remain the best options... - Loss of bone mineral density after antiretroviral therapy initiation, independent of antiretroviral regimenTodd T Brown
Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore, MD, USA
J Acquir Immune Defic Syndr 51:554-61. 2009..Decreased bone mineral density (BMD) has been described in HIV-infected patients initiating antiretroviral therapy (ART), but the contributions of ART and immunologic and/or virologic factors remain unclear... - Metabolic abnormalities in HIV disease and injection drug useAdrian Dobs
The John Hopkins University School of Medicine, Baltimore, Maryland, USA
J Acquir Immune Defic Syndr 31:S70-7. 2002..The issues covered are current estimations of prevalence, risk factors, underlying pathophysiology, diagnosis, and interventions (prevention and treatment) for metabolic complications of HIV and drug abuse... - Fish oil supplementation in the treatment of cachexia in pancreatic cancer patientsTodd T Brown
Johns Hopkins University School of Medicine, Division of Endocrinology and Metabolism, Center for Complementary and Alternative Medicine, Baltimore, MD 21287, USA
Int J Gastrointest Cancer 34:143-50. 2003..Concerns about standardization and quality control should also be considered. With the current available evidence, a recommendation for the use of omega 3 polyunsaturated fatty acids in pancreatic cancer cachexia is premature... - Thyroid function abnormalities in HIV-infected patientsChristopher J Hoffmann
Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
Clin Infect Dis 45:488-94. 2007.... - Management of morphologic changes associated with antiretroviral use in HIV-infected patientsDavid Alain Wohl
AIDS Clinical Trials Unit, University of North Carolina, Chapel Hill, NC 27599, USA
J Acquir Immune Defic Syndr 49:S93-S100. 2008..The potential increase in risk of cardiovascular disease associated with these metabolic disturbances is also discussed... - Cortisol levels and depression in men and women using heroin and cocaineAmy B Wisniewski
Department of Biology, Drake University, 328 Olin Hall, 1344 27th Street, Des Moines, IA 50311 4505, USA
Psychoneuroendocrinology 31:250-5. 2006.... - Hypothalamic-pituitary-gonadal function in men and women using heroin and cocaine, stratified by HIV statusAmy B Wisniewski
Department of Biology, Drake University, Des Moines, Iowa 50311 4505, USA
Gend Med 4:35-44. 2007..Most studies of hypothalamic-pituitary-gonadal (HPG) function in illicit drug users either focus on men or do not consider the impact of HIV... - Response to Berg et al. 'Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic review'Todd T Brown
AIDS 21:1830-1. 2007 - Report from Boston: the 12th Conference on Retroviruses and Opportunistic Infections (CROI). Reduced bone mineral density in HIV-infected patientsTodd T Brown
Hopkins HIV Rep 17:12-4, 16. 2005 - Prevention strategies for cardiovascular disease in HIV-infected patientsJames H Stein
Circulation 118:e54-60. 2008 - Fracture prevalence among human immunodeficiency virus (HIV)-infected versus non-HIV-infected patients in a large U.S. healthcare systemVirginia A Triant
Program in Nutritional Metabolism, Massachusetts General Hospital, 55 Fruit Street, Longfellow 207, Boston, Massachusetts 02114
J Clin Endocrinol Metab 93:3499-504. 2008..Reduced bone mineral density has been demonstrated among HIV-infected patients, but fracture prevalence is unknown...
Research Grants
- Fish oil, inflammation, & metabolic complications in HIVTodd Brown; Fiscal Year: 2007..This proposal will also help me attain my goal of becoming an independent investigator in the area of CAM and HIV. ..