Amanda M Brown

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Multiple human immunodeficiency virus type 1 Nef functions contribute to efficient replication in primary human macrophages
    Amanda Brown
    Aaron Diamond AIDS Research Center, The Rockefeller University, 455 First Avenue, 7th Floor, New York, NY 10016, USA
    J Gen Virol 85:1463-9. 2004
  2. ncbi request reprint HLA-A2 down-regulation on primary human macrophages infected with an M-tropic EGFP-tagged HIV-1 reporter virus
    Amanda Brown
    Department of Neurology, Meyer 6 181, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Leukoc Biol 78:675-85. 2005
  3. ncbi request reprint In vitro modeling of the HIV-macrophage reservoir
    Amanda Brown
    Johns Hopkins School of Medicine, Department of Neurology, 600 North Wolfe St, Baltimore, MD 21287, USA
    J Leukoc Biol 80:1127-35. 2006
  4. doi request reprint Use of a macrophage-tropic GFP-tagged human immunodeficiency virus type 1 (HIV-1) to study viral reservoirs
    Amanda M Brown
    Johns Hopkins University School of Medicine, Neurology, Baltimore, MD 21287, USA
    Methods Mol Biol 515:165-75. 2009
  5. pmc Osteopontin enhances HIV replication and is increased in the brain and cerebrospinal fluid of HIV-infected individuals
    Amanda Brown
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287 7131, USA
    J Neurovirol 17:382-92. 2011

Detail Information

Publications5

  1. ncbi request reprint Multiple human immunodeficiency virus type 1 Nef functions contribute to efficient replication in primary human macrophages
    Amanda Brown
    Aaron Diamond AIDS Research Center, The Rockefeller University, 455 First Avenue, 7th Floor, New York, NY 10016, USA
    J Gen Virol 85:1463-9. 2004
    ..These data suggest that efficient HIV-1 replication is dependent on the ability of Nef to interact with cellular kinases and remove CD4 from the surface of infected macrophages...
  2. ncbi request reprint HLA-A2 down-regulation on primary human macrophages infected with an M-tropic EGFP-tagged HIV-1 reporter virus
    Amanda Brown
    Department of Neurology, Meyer 6 181, 600 North Wolfe Street, Baltimore, MD 21287, USA
    J Leukoc Biol 78:675-85. 2005
    ..The impact of Nef on HLA-A2 surface expression in MDM was also confirmed by confocal microscopy. These results suggest that the mechanisms of HLA-A2 down-modulation are similar in primary T cells and macrophages...
  3. ncbi request reprint In vitro modeling of the HIV-macrophage reservoir
    Amanda Brown
    Johns Hopkins School of Medicine, Department of Neurology, 600 North Wolfe St, Baltimore, MD 21287, USA
    J Leukoc Biol 80:1127-35. 2006
    ..A subset of these, were replication competent as shown by their ability to express GFP and/or p24 antigen after reactivation with IL-4...
  4. doi request reprint Use of a macrophage-tropic GFP-tagged human immunodeficiency virus type 1 (HIV-1) to study viral reservoirs
    Amanda M Brown
    Johns Hopkins University School of Medicine, Neurology, Baltimore, MD 21287, USA
    Methods Mol Biol 515:165-75. 2009
    ..The infected cells can be studied at the single-cell level using a variety of fluorescence-based technologies such as flow cytometry, conventional and confocal microscopy, and laser capture microdissection...
  5. pmc Osteopontin enhances HIV replication and is increased in the brain and cerebrospinal fluid of HIV-infected individuals
    Amanda Brown
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287 7131, USA
    J Neurovirol 17:382-92. 2011
    ....