Daniel J Brotman

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Limitations of D-dimer testing in unselected inpatients with suspected venous thromboembolism
    Daniel J Brotman
    Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA
    Am J Med 114:276-82. 2003
  2. ncbi The cardiovascular toll of stress
    Daniel J Brotman
    Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Lancet 370:1089-100. 2007
  3. ncbi Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment
    Jeetesh V Patel
    Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine and Sandwell Medical Research Unit, Sandwell and West Birmingham Hospitals NHS Trust, West Midlands, UK
    J Negat Results Biomed 5:14. 2006
  4. ncbi Heart rate variability predicts ESRD and CKD-related hospitalization
    Daniel J Brotman
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Soc Nephrol 21:1560-70. 2010
  5. ncbi Impaired diurnal blood pressure variation and all-cause mortality
    Daniel J Brotman
    Hospitalist Program, Division of General Internal Medicine, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    Am J Hypertens 21:92-7. 2008
  6. ncbi Acute changes in N-terminal pro-B-type natriuretic peptide during hospitalization and risk of readmission and mortality in patients with heart failure
    Henry J Michtalik
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 107:1191-5. 2011
  7. ncbi Effects of short-term glucocorticoids on cardiovascular biomarkers
    Daniel J Brotman
    Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Clin Endocrinol Metab 90:3202-8. 2005
  8. ncbi Beyond cardiovascular risk: the impact of obesity on cancer death
    Bryan C Bordeaux
    Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cleve Clin J Med 73:945-50. 2006
  9. ncbi Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systematic review
    Jodi B Segal
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    JAMA 301:2472-85. 2009
  10. ncbi Analytic validity of genetic tests to identify factor V Leiden and prothrombin G20210A
    Ashkan Emadi
    Department of Internal Medicine, Johns Hopkins University, Baltimore, MD, USA
    Am J Hematol 85:264-70. 2010

Collaborators

Detail Information

Publications37

  1. ncbi Limitations of D-dimer testing in unselected inpatients with suspected venous thromboembolism
    Daniel J Brotman
    Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA
    Am J Med 114:276-82. 2003
    ..To determine the utility and limitations of D-dimer testing for the evaluation of venous thromboembolism in hospitalized patients...
  2. ncbi The cardiovascular toll of stress
    Daniel J Brotman
    Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Lancet 370:1089-100. 2007
    ..We provide an overview of the association between stress and cardiovascular morbidity, discuss the mechanisms for this association, and address possible therapeutic implications...
  3. ncbi Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment
    Jeetesh V Patel
    Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine and Sandwell Medical Research Unit, Sandwell and West Birmingham Hospitals NHS Trust, West Midlands, UK
    J Negat Results Biomed 5:14. 2006
    ..Little is known about the effects of short-term glucocorticoid treatment on levels of these hormones...
  4. ncbi Heart rate variability predicts ESRD and CKD-related hospitalization
    Daniel J Brotman
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Soc Nephrol 21:1560-70. 2010
    ..These results suggest that autonomic dysfunction may be an important risk factor for ESRD and CKD-related hospitalizations and call for further studies to define the mechanisms that underlie these associations...
  5. ncbi Impaired diurnal blood pressure variation and all-cause mortality
    Daniel J Brotman
    Hospitalist Program, Division of General Internal Medicine, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD, USA
    Am J Hypertens 21:92-7. 2008
    ..A drop of <10% from mean daytime values, "non-dipping," is associated with kidney disease and cardiovascular events. We hypothesized that non-dipping would predict all-cause mortality...
  6. ncbi Acute changes in N-terminal pro-B-type natriuretic peptide during hospitalization and risk of readmission and mortality in patients with heart failure
    Henry J Michtalik
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 107:1191-5. 2011
    ..In conclusion, patients with a < 50% reduction in NT-proBNP might benefit from more intensive medical treatment, monitoring, and follow-up...
  7. ncbi Effects of short-term glucocorticoids on cardiovascular biomarkers
    Daniel J Brotman
    Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Clin Endocrinol Metab 90:3202-8. 2005
    ..However, the short-term effects of glucocorticoids on other cardiovascular risk factors remain incompletely characterized...
  8. ncbi Beyond cardiovascular risk: the impact of obesity on cancer death
    Bryan C Bordeaux
    Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Cleve Clin J Med 73:945-50. 2006
    ..These problems represent opportunities to improve the care of obese patients...
  9. ncbi Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systematic review
    Jodi B Segal
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    JAMA 301:2472-85. 2009
    ..Testing for genetic risks for venous thromboembolism (VTE) is common, but the safety and utility of such testing need review...
  10. ncbi Analytic validity of genetic tests to identify factor V Leiden and prothrombin G20210A
    Ashkan Emadi
    Department of Internal Medicine, Johns Hopkins University, Baltimore, MD, USA
    Am J Hematol 85:264-70. 2010
    ..There is high-grade evidence that most, but not all, clinical laboratories test for FVL and prothrombin G20210A accurately...
  11. ncbi Usefulness of cystatin C and prognosis following admission for acute heart failure
    Catherine Y Campbell
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 104:389-92. 2009
    ..In conclusion, cystatin C may be useful in addition to creatinine for predicting outcomes after admission for acute heart failure exacerbations...
  12. ncbi Perioperative statins: more than lipid-lowering?
    Leonard S Feldman
    Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Cleve Clin J Med 75:654-62. 2008
    ..Although more studies are needed to draw firm conclusions, the acute nonlipid pleiotropic effects of statins may improve patient outcomes, especially for patients at the highest risk...
  13. ncbi Prevention of venous thromboembolism in the hospitalized medical patient
    Amir K Jaffer
    Department of Medicine, Leonard M Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Cleve Clin J Med 75:S7-16. 2008
    ....
  14. ncbi Increase in nocturnal blood pressure and progression to microalbuminuria in diabetes
    Daniel J Brotman
    N Engl J Med 348:260-4; author reply 260-4. 2003
  15. ncbi Mediators of the association between mortality risk and socioeconomic status
    Daniel J Brotman
    JAMA 296:763-4; author reply 764. 2006
  16. ncbi Association of impaired diurnal blood pressure variation with a subsequent decline in glomerular filtration rate
    Michael B Davidson
    Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Arch Intern Med 166:846-52. 2006
    ..CONCLUSION: Blunted diurnal blood pressure variation is associated with a subsequent deterioration in renal function that is independent of SBP load and other risk factors for renal impairment...
  17. ncbi Racial differences in diurnal blood pressure and heart rate patterns: results from the Dietary Approaches to Stop Hypertension (DASH) trial
    Megan L Jehn
    School of Health Management and Policy, Arizona State University, PO Box 874506, Tempe, AZ 85287 4506, USA
    Arch Intern Med 168:996-1002. 2008
    ..It is unknown whether differences in traditional determinants of BP, specifically diet and obesity, account for observed differences in diurnal patterns...
  18. ncbi Does altered glucocorticoid homeostasis increase cardiovascular risk?
    John P Girod
    Hospital Medicine Fellowship, Department of General Internal Medicine S70, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Cardiovasc Res 64:217-26. 2004
    ..Nevertheless, the known effects of exogenous glucocorticoids provide important insights into the putative effects of endogenous glucocorticoids...
  19. ncbi Can glucocorticoid homeostasis explain the antiatherogenic effect of peripheral adiposity?
    Daniel J Brotman
    Circulation 108:e61; author reply e61. 2003
  20. ncbi Relation of diurnal blood pressure variation and triglyceride-to-high-density lipoprotein cholesterol ratio in patients without diabetes mellitus
    Michael B Davidson
    Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 95:123-6. 2005
    ..3, 95% confidence interval 2.6 to 16.4, p <0.0001) before the development of abnormal levels of fasting blood glucose...
  21. ncbi Outcomes of patients with stable heart failure undergoing elective noncardiac surgery
    Ye Olivia Xu-Cai
    Department of Hospital Medicine, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Mayo Clin Proc 83:280-8. 2008
    ....
  22. ncbi Prevention of venous thromboembolism in the orthopedic surgery patient
    Steven B Deitelzweig
    Department of Hospital Medicine, Ochsner Health System, New Orleans, LA 70121, USA
    Cleve Clin J Med 75:S27-36. 2008
    ..Extended-duration prophylaxis (for 4 to 5 weeks) is now recommended for patients undergoing hip arthroplasty or hip fracture repair. Patients undergoing knee arthroscopy do not require routine pharmacologic VTE prophylaxis...
  23. ncbi Prevention of venous thromboembolism in the cancer surgery patient
    Alex C Spyropoulos
    Clinical Thrombosis Center, Lovelace Medical Center, Albuquerque, NM 87108, USA
    Cleve Clin J Med 75:S17-26. 2008
    ..The risk-benefit profile of low-dose anticoagulant prophylaxis appears to be favorable even in many cancer patients undergoing neurosurgery, for whom pharmacologic VTE prophylaxis has been controversial because of bleeding risks...
  24. ncbi Missing the forest for the trees
    Satish Gopal
    Department of Internal Medicine, Norwalk Hospital, Norwalk, Connecticut, USA
    J Hosp Med 2:105-9. 2007
  25. ncbi Prevention of venous thromboembolism in the geriatric patient
    Amir K Jaffer
    The Internal Medicine Preoperative Assessment Consultation and Treatment Center, Anticoagulation Clinic, The Cleveland Clinic Foundation, OH 44195, USA
    Clin Geriatr Med 22:93-111, ix. 2006
    ..It is recommended that the clinician carefully evaluate the elderly patient's creatinine clearance and weight before prescribing anticoagulants, particularly when using fixed dosing regimens...
  26. ncbi The metabolic syndrome: a tug-of-war with no winner
    Daniel J Brotman
    Cleve Clin J Med 69:990-4. 2002
    ..Even before beta cells fail and type 2 diabetes ensues, the deadly quartet is quietly rehearsing...
  27. ncbi Narrow-complex tachycardia in an elderly patient with presyncope
    M Faisal Jhandir
    Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Emerg Med 24:217-9. 2003
  28. ncbi The metabolic syndrome as a vicious cycle: does obesity beget obesity?
    John P Girod
    Department of General Internal Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
    Med Hypotheses 60:584-9. 2003
    ..We also outline mechanisms by which obesity may perpetuate low GH and increased glucocorticoid activity in the metabolic syndrome...
  29. ncbi Acetaminophen and hypertension: a causal association or pain mediated?
    Daniel J Brotman
    Arch Intern Med 163:1113-4; author reply 1115-6. 2003
  30. ncbi Does glucocorticoid dysregulation contribute to the link between cigarette smoking and insulin resistance?
    John P Girod
    J Am Coll Cardiol 42:771; author reply 771-2. 2003
  31. ncbi When patients on warfarin need surgery
    Amir K Jaffer
    The Internal Medicine Preoperative Assessment Consultation and Treatment IMPACT Center, Department of General Internal Medicine, The Cleveland Clinic Foundation, OH 44195, USA
    Cleve Clin J Med 70:973-84. 2003
    ..We believe most patients should stop taking warfarin 5 days before elective surgery, and most do not need to receive heparin in the perioperative period as a bridge to surgery...
  32. ncbi In search of fewer independent risk factors
    Daniel J Brotman
    Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Arch Intern Med 165:138-45. 2005
    ..A glossary and schema are provided to help clinicians and researchers understand and discuss these matters effectively...
  33. ncbi Current and emerging options in the management of venous thromboembolism
    Amir K Jaffer
    IMPACT Investigators Group, Section of Hospital Medicine, Department of General Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Cleve Clin J Med 72:S14-23. 2005
    ..Newer anticoagulants such as the factor Xa inhibitor fondaparinux also show promise for acute VTE. For chronic management, the duration and intensity of warfarin therapy should be tailored to the individual patient...
  34. ncbi "Regression" of adiposity with more sleep
    Daniel J Brotman
    Arch Intern Med 165:1314-5; author reply 1315. 2005
  35. ncbi Effects of short-term glucocorticoids on hemostatic factors in healthy volunteers
    Daniel J Brotman
    Department of General Internal Medicine, Cleveland Clinic Foundation, OH, USA
    Thromb Res 118:247-52. 2006
    ..05). CONCLUSIONS: Glucocorticoids may increase the activity of clotting factors in vivo. This may contribute to the reported increased risk of thrombosis in patients with sustained exposure to glucocorticoids...
  36. ncbi Relation of brachial artery reactivity to nitroglycerin and heart rate recovery following exercise in healthy male volunteers
    John P Girod
    Department of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Cardiol 96:447-9. 2005
    ..This suggests that parasympathetic tone may be inversely related to the responsiveness of arterial smooth muscle to nitrates in healthy humans...
  37. ncbi Effects of counterregulatory hormones in a high-glycemic index diet
    Daniel J Brotman
    JAMA 288:695; author reply 695. 2002