Ronald Brookmeyer

Summary

Affiliation: Johns Hopkins Bloomberg School of Public Health
Country: USA

Publications

  1. ncbi Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
    R Brookmeyer
    Department of Biostatistics, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 22105 2179, USA
    Am J Public Health 88:1337-42. 1998
  2. ncbi Should biomarker estimates of HIV incidence be adjusted?
    Ron Brookmeyer
    Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, New Jersey, USA
    AIDS 23:485-91. 2009
  3. ncbi A hypothesis test for the end of a common source outbreak
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Biometrics 62:61-5. 2006
  4. ncbi Modelling the incubation period of anthrax
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Stat Med 24:531-42. 2005
  5. ncbi Public health vaccination policies for containing an anthrax outbreak
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA
    Nature 432:901-4. 2004
  6. ncbi Modeling the optimum duration of antibiotic prophylaxis in an anthrax outbreak
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 100:10129-32. 2003
  7. ncbi Survival following a diagnosis of Alzheimer disease
    Ron Brookmeyer
    Department of Biostatistics, The Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    Arch Neurol 59:1764-7. 2002
  8. ncbi Survival curve estimation with partial non-random exposure information
    Ron Brookmeyer
    Johns Hopkins University, School of Hygiene and Public Health, Department of Biostatistics, 615 North Wolfe Street, Baltimore, Maryland 21205, USA
    Stat Med 21:2671-83. 2002
  9. ncbi Prevention of inhalational anthrax in the U.S. outbreak
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Science 295:1861. 2002
  10. ncbi Analysis of multistage pooling studies of biological specimens for estimating disease incidence and prevalence
    R Brookmeyer
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205 2179, USA
    Biometrics 55:608-12. 1999

Research Grants

  1. STATISTICAL METHODS IN AIDS RESEARCH
    Ronald Brookmeyer; Fiscal Year: 2001
  2. Statistical Methods for Partially Controlled Studies
    Ronald Brookmeyer; Fiscal Year: 2003
  3. Statistical Models for Anthrax
    Ronald Brookmeyer; Fiscal Year: 2003

Detail Information

Publications26

  1. ncbi Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
    R Brookmeyer
    Department of Biostatistics, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 22105 2179, USA
    Am J Public Health 88:1337-42. 1998
    ..The goal of this study was to project the future prevalence and incidence of Alzheimer's disease in the United States and the potential impact of interventions to delay disease onset...
  2. ncbi Should biomarker estimates of HIV incidence be adjusted?
    Ron Brookmeyer
    Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, New Jersey, USA
    AIDS 23:485-91. 2009
    ..g. BED capture enzyme immunoassay). These procedures were motivated by some reports that the biomarker BED approach overestimates incidence when compared to cohort studies...
  3. ncbi A hypothesis test for the end of a common source outbreak
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Biometrics 62:61-5. 2006
    ..We derive expressions for the outbreak-wise type I error probability and show that multiple testing has minimal effect on inflating that error probability. The results are discussed in the context of the 2001 U.S. anthrax outbreak...
  4. ncbi Modelling the incubation period of anthrax
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Stat Med 24:531-42. 2005
    ..Male gender and younger ages were associated with longer incubation periods as was lower dose of inhaled spores...
  5. ncbi Public health vaccination policies for containing an anthrax outbreak
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, Maryland 21205, USA
    Nature 432:901-4. 2004
    ....
  6. ncbi Modeling the optimum duration of antibiotic prophylaxis in an anthrax outbreak
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 100:10129-32. 2003
    ..S. outbreak, because doses were very low, at moderate or high doses considerably longer durations would be necessary to adequately protect exposed populations...
  7. ncbi Survival following a diagnosis of Alzheimer disease
    Ron Brookmeyer
    Department of Biostatistics, The Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    Arch Neurol 59:1764-7. 2002
    ..Survival following a diagnosis of Alzheimer disease (AD) is important information for health planners, caregivers, patients, and their families...
  8. ncbi Survival curve estimation with partial non-random exposure information
    Ron Brookmeyer
    Johns Hopkins University, School of Hygiene and Public Health, Department of Biostatistics, 615 North Wolfe Street, Baltimore, Maryland 21205, USA
    Stat Med 21:2671-83. 2002
    ..A simulation is performed to evaluate the bias of the estimators and to investigate design and efficiency issues. The methods are applied to the Alzheimer's disease study...
  9. ncbi Prevention of inhalational anthrax in the U.S. outbreak
    Ron Brookmeyer
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Science 295:1861. 2002
  10. ncbi Analysis of multistage pooling studies of biological specimens for estimating disease incidence and prevalence
    R Brookmeyer
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205 2179, USA
    Biometrics 55:608-12. 1999
    ..The results are extended to estimating disease incidence rates. The methods are used to estimate HIV incidence rates from a prevalence study of early HIV infection using a PCR assay for HIV RNA...
  11. ncbi Methods for projecting the incidence and prevalence of chronic diseases in aging populations: application to Alzheimer's disease
    R Brookmeyer
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Stat Med 19:1481-93. 2000
    ..In order to perform the calculations, we have assembled U.S. Census population projections and U.S. mortality rates into computer software that is available from the authors at www.jhsph.edu/Departments/Biostats/software.h tml...
  12. ncbi Person-time analysis of paired community intervention trials when the number of communities is small
    R Brookmeyer
    Department of Biostatistics, Johns Hopkins University, Baltimore, MD 21205 2179, USA
    Stat Med 17:2121-32. 1998
    ..We consider methods to account for individual level covariates. Motivation for this work came from recent randomized community intervention trials in Africa to prevent transmission of the human immunodeficiency virus (HIV)...
  13. ncbi Web-based application to project the burden of Alzheimer's disease
    Elizabeth Colantuoni
    Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA
    Alzheimers Dement 6:425-8. 2010
    ..Health care planning and research would benefit from tools that enable researchers to project the future burden of Alzheimer's disease (AD) and evaluate the effect of potential interventions...
  14. ncbi Identifying the probable timing and setting of respiratory virus infections
    Justin Lessler
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, and the Department of Hospital Epidemiology and Infection Control, Johns Hopkins Hospital, Baltimore, Maryland 21205, USA
    Infect Control Hosp Epidemiol 31:809-15. 2010
    ..Show how detailed incubation period estimates can be used to identify and investigate potential healthcare-associated infections and dangerous diseases...
  15. ncbi Estimating incubation period distributions with coarse data
    Nicholas G Reich
    Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Stat Med 28:2769-84. 2009
    ..However for estimation of the tails of the distribution, the doubly interval-censored analysis is the recommended procedure...
  16. ncbi An evaluation of classification rules based on date of symptom onset to identify health-care associated infections
    Justin Lessler
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Epidemiol 166:1220-9. 2007
    ..These results increase the utility of classifying infections by use of the date of onset by providing theoretically sound measures of performance, and they are applicable beyond the hospital setting...
  17. ncbi H1N1pdm in the Americas
    Justin Lessler
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
    Epidemics 2:132-8. 2010
    ..To the extent that latitude is a proxy for seasonal changes in climate and behavior, this association suggests a strong seasonal component to H1N1pdm transmission. However, the reasons for this seasonality remain unclear...
  18. ncbi Confidence intervals for biomarker-based human immunodeficiency virus incidence estimates and differences using prevalent data
    Stephen R Cole
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Am J Epidemiol 165:94-100. 2007
    ..The Monte Carlo-based CI may be preferable to competing methods because of the ease of extension to the incidence difference or to exploration of departures from assumptions...
  19. ncbi Assessing the magnitude of the HIV/AIDS epidemic in Burma
    Chris Beyrer
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    J Acquir Immune Defic Syndr 32:311-7. 2003
    ..Estimates of the HIV/AIDS burden in Burma (Myanmar) are uncertain. Using data from the 1999 national HIV sentinel surveillance and available population data, we generated estimates of Burma's HIV burden in 1999...
  20. ncbi On the statistical accuracy of biomarker assays for HIV incidence
    Ron Brookmeyer
    Department of Biostatistics, School of Public Health, University of California, Los Angeles, CA, USA
    J Acquir Immune Defic Syndr 54:406-14. 2010
    ..To evaluate the statistical accuracy of estimates of current HIV incidence rates from cross-sectional surveys, and to identify characteristics of assays that improve accuracy...
  21. ncbi Measuring the HIV/AIDS epidemic: approaches and challenges
    Ron Brookmeyer
    Department of Biostatistics, School of Public Health, University of California, Los Angeles, Los Angeles, California 90095, USA
    Epidemiol Rev 32:26-37. 2010
    ....
  22. ncbi Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study
    Martin Steinberg
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Int J Geriatr Psychiatry 23:170-7. 2008
    ..Neuropsychiatric symptoms are nearly universal in dementia, yet little is known about their longitudinal course in the community...
  23. ncbi Validity of self-reported needle exchange attendance among injection drug users: implications for program evaluation
    Mahboobeh Safaeian
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 155:169-75. 2002
    ..These findings have important implications for evaluations of NEPs...
  24. ncbi Incubation periods of acute respiratory viral infections: a systematic review
    Justin Lessler
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Lancet Infect Dis 9:291-300. 2009
    ..Our estimates combine published data to give the detail necessary for these and other applications...
  25. ncbi Regional and temporal variation in American Red Cross blood donations, 1995 to 2005
    Stephen O Crawford
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
    Transfusion 48:1576-83. 2008
    ..Maintaining a stable blood supply is a critical goal of the American Red Cross Blood Services. Extensive Red Cross data provided the opportunity to assess both long-term and short-term trends in the variation of weekly blood donations...
  26. ncbi Male circumcision and risk of HIV-1 and other sexually transmitted infections in India
    Steven J Reynolds
    Division of Infectious Diseases, Johns Hopkins University Medical School, Ross 1150, 720 Rutland Avenue, Baltimore, Maryland 21205, USA
    Lancet 363:1039-40. 2004
    ..The specificity of this relation suggests a biological rather than behavioural explanation for the protective effect of male circumcision against HIV-1...

Research Grants5

  1. STATISTICAL METHODS IN AIDS RESEARCH
    Ronald Brookmeyer; Fiscal Year: 2001
    ..The methods will be applied to the ALIVE study. ..
  2. Statistical Methods for Partially Controlled Studies
    Ronald Brookmeyer; Fiscal Year: 2003
    ..This work is essential for preserving generalizability of results from long follow-up studies, and we will apply it to better evaluate time to potential drug dependence in youths. ..
  3. Statistical Models for Anthrax
    Ronald Brookmeyer; Fiscal Year: 2003
    ..This work will depend on results from specific aims 1 and 2. ..