Research Topics

Genomes and Genes

Affiliation: Johns Hopkins University

Country: USA

Analysis of the role of PCNA-DNA contacts during clamp loading
Randall McNally
Department of Molecular and Cell Biology, Department of Chemistry, California Institute for Quantitative Biosciences QB3, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA
BMC Struct Biol 10:3. 2010
Mechanisms of ATP-dependent nucleosome sliding
Gregory D Bowman
T C Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218 2685, USA
Curr Opin Struct Biol 20:73-81. 2010
Extranucleosomal DNA binding directs nucleosome sliding by Chd1
Jeffrey N McKnight
TC Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218 2685, USA
Mol Cell Biol 31:4746-59. 2011

Analysis of the role of PCNA-DNA contacts during clamp loading
Randall McNally
Department of Molecular and Cell Biology, Department of Chemistry, California Institute for Quantitative Biosciences QB3, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA
BMC Struct Biol 10:3. 2010
..In an ATP-dependent reaction, clamp loader complexes, such as the Replication Factor-C (RFC) complex in eukaryotes, open the clamp and load it around primer-template DNA...
Mechanisms of ATP-dependent nucleosome sliding
Gregory D Bowman
T C Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218 2685, USA
Curr Opin Struct Biol 20:73-81. 2010
..Advantages and challenges of several nucleosome sliding models are discussed...
Extranucleosomal DNA binding directs nucleosome sliding by Chd1
Jeffrey N McKnight
TC Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218 2685, USA
Mol Cell Biol 31:4746-59. 2011
..These results suggest that the DNA-binding domain's affinity for extranucleosomal DNA is the key determinant for the direction that Chd1 shifts the nucleosome...