Diane M Becker

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi Nurse-mediated cholesterol management compared with enhanced primary care in siblings of individuals with premature coronary disease
    D M Becker
    Center for Health Promotion, Johns Hopkins University, Baltimore, MD 21205, USA
    Arch Intern Med 158:1533-9. 1998
  2. ncbi Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1
    Nauder Faraday
    Department of Anesthesiology Critical Care Medicine, Division of Cardiac Surgical Intensive Care, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Circulation 115:2490-6. 2007
  3. ncbi A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease
    Rasika A Mathias
    Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD, USA
    BMC Med Genomics 3:22. 2010
  4. ncbi Sustainability of a multiple risk factor intervention on cardiovascular disease in high-risk African American families
    Crystal W Cene
    Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Ethn Dis 18:169-75. 2008
  5. ncbi A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability
    J Enrique Herrera-Galeano
    Departments of Medicine and Anesthesiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Arterioscler Thromb Vasc Biol 28:1484-90. 2008
  6. ncbi Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease
    Rehan Qayyum
    Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 101:1359-63. 2008
  7. ncbi Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression
    Nauder Faraday
    Department of Anesthesiology and Critical Care Medicine, J ohns Hopkins University School of Medicine, Baltimore, MD, USA
    Blood 118:3367-75. 2011
  8. ncbi Ethnic-specific determinants of exercise capacity in a healthy high-risk population
    Rochelle V Brown
    Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Med Sci Sports Exerc 44:1150-6. 2012
  9. ncbi Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population
    Nauder Faraday
    Division of Cardiac Surgical Intensive Care, Department of Anesthesiology Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Am J Cardiol 98:774-9. 2006
  10. ncbi Native platelet aggregation and response to aspirin in persons with the metabolic syndrome and its components
    Dhananjay Vaidya
    Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Metab Syndr Relat Disord 7:289-96. 2009

Detail Information

Publications32

  1. ncbi Nurse-mediated cholesterol management compared with enhanced primary care in siblings of individuals with premature coronary disease
    D M Becker
    Center for Health Promotion, Johns Hopkins University, Baltimore, MD 21205, USA
    Arch Intern Med 158:1533-9. 1998
    ..Siblings of individuals with premature coronary heart disease have a high prevalence of low-density lipoprotein cholesterol (LDL-C) levels requiring treatment...
  2. ncbi Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1
    Nauder Faraday
    Department of Anesthesiology Critical Care Medicine, Division of Cardiac Surgical Intensive Care, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Circulation 115:2490-6. 2007
    ..Genetic variation is a proposed but unproved mechanism for insufficient ASA responsiveness...
  3. ncbi A combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in European American and African American families with coronary artery disease
    Rasika A Mathias
    Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD, USA
    BMC Med Genomics 3:22. 2010
    ..In this study, we leverage independent information from genome-wide linkage and association data to determine loci controlling platelet phenotypes before and after treatment with ASA...
  4. ncbi Sustainability of a multiple risk factor intervention on cardiovascular disease in high-risk African American families
    Crystal W Cene
    Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Ethn Dis 18:169-75. 2008
    ....
  5. ncbi A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability
    J Enrique Herrera-Galeano
    Departments of Medicine and Anesthesiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Arterioscler Thromb Vasc Biol 28:1484-90. 2008
    ..We looked for novel genetic variants in PEAR1 and studied their association with agonist-induced native platelet aggregation and with the inhibitory effect of aspirin on platelets...
  6. ncbi Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease
    Rehan Qayyum
    Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 101:1359-63. 2008
    ..In conclusion, women continue to have greater residual platelet activity after high-dose aspirin compared with men treated with a lower dose of aspirin...
  7. ncbi Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression
    Nauder Faraday
    Department of Anesthesiology and Critical Care Medicine, J ohns Hopkins University School of Medicine, Baltimore, MD, USA
    Blood 118:3367-75. 2011
    ....
  8. ncbi Ethnic-specific determinants of exercise capacity in a healthy high-risk population
    Rochelle V Brown
    Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Med Sci Sports Exerc 44:1150-6. 2012
    ..We thus examined exercise capacity and its biopsychosocial correlates in a healthy population of AA and EA at increased risk of CVD...
  9. ncbi Relation between atherosclerosis risk factors and aspirin resistance in a primary prevention population
    Nauder Faraday
    Division of Cardiac Surgical Intensive Care, Department of Anesthesiology Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Am J Cardiol 98:774-9. 2006
    ..quot;..
  10. ncbi Native platelet aggregation and response to aspirin in persons with the metabolic syndrome and its components
    Dhananjay Vaidya
    Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Metab Syndr Relat Disord 7:289-96. 2009
    ..We determined the extent to which persons with increased risk for CAD with and without the metabolic syndrome accrued antiplatelet benefits from aspirin therapy...
  11. ncbi Severity of inducible myocardial ischemia predicts incident acute coronary syndromes in asymptomatic individuals with a family history of premature coronary artery disease
    Brian G Kral
    Division of Cardiology, Department of Medicine, The Johns Hopkins GeneSTAR Research Program, The Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    J Nucl Cardiol 19:28-36. 2012
    ....
  12. ncbi Leukocyte count is associated with increased platelet reactivity and diminished response to aspirin in healthy individuals with a family history of coronary artery disease
    Nauder Faraday
    Department of Anesthesiology Critical Care Medicine, Division of Cardiac Surgical Intensive Care, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Thromb Res 124:311-7. 2009
    ..Leukocytes may promote platelet reactivity and thrombus formation, providing a basis for increased risk, but a relation between leukocyte count and platelet function has not been studied...
  13. ncbi Pharmacogenomics of platelet responsiveness to aspirin
    Nauder Faraday
    Johns Hopkins University School of Medicine, Department of Anesthesiology Critical Care Medicine, Division of Cardiac Surgical Intensive Care, 298 Meyer Bldg, 600 N Wolfe St, Baltimore, MD 21287, USA
    Pharmacogenomics 8:1413-25. 2007
    ....
  14. ncbi Single nucleotide polymorphisms in monocyte chemoattractant protein-1 and its receptor act synergistically to increase the risk of carotid atherosclerosis
    Paul A Nyquist
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Cerebrovasc Dis 28:124-30. 2009
    ....
  15. ncbi Comparison of coronary calcium and stress myocardial perfusion imaging in apparently healthy siblings of individuals with premature coronary artery disease
    Roger S Blumenthal
    The Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 97:328-33. 2006
    ..These screening tests may reflect different aspects or stages of coronary disease in an asymptomatic middle-age population...
  16. ncbi The robustness of generalized estimating equations for association tests in extended family data
    Bhoom Suktitipat
    Genometrics Section, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21205, USA
    Hum Hered 74:17-26. 2012
    ....
  17. ncbi Casual chocolate consumption and inhibition of platelet function
    Bryan Bordeaux
    Department of Medicine, Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Prev Cardiol 10:175-80. 2007
    ..The authors concluded that even consuming modest amounts of commercial chocolate has important antiplatelet effects...
  18. ncbi The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans
    Rasika A Mathias
    Division of General Internal Medicine, Department of Medicine, The GeneSTAR Research Program, The Johns Hopkins University, Baltimore, MD 21224, USA
    BMC Genet 12:50. 2011
    ....
  19. ncbi Silent myocardial ischaemia and long-term coronary artery disease outcomes in apparently healthy people from families with early-onset ischaemic heart disease
    Brian G Kral
    The Johns Hopkins GeneSTAR Research Program, Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, 1830 East Monument Street, Room 8023, Baltimore, MD 21287, USA
    Eur Heart J 32:2766-72. 2011
    ..The extent to which inducible myocardial ischaemia exists and is associated with long-term incident CAD in apparently healthy siblings of early-onset CAD patients is unknown...
  20. ncbi Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease
    Stasia S Reynolds
    Divisions of General Internal Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Diabetes Res Clin Pract 74:267-73. 2006
    ..867. CONCLUSION: Higher FPG levels within the designated "normal" range in high risk families are a potent independent risk factor for type 2 diabetes and may serve as a sentinel to trigger primary preventive interventions...
  21. ncbi Independent metabolic syndrome variants predict new-onset coronary artery disease
    Dhananjay Vaidya
    Department of Medicine, Division of General Internal Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Diabetes Care 33:1376-8. 2010
    ....
  22. ncbi A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry
    Brian G Kral
    Department of Medicine, The Johns Hopkins GeneSTAR Research Program, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Hum Genet 56:224-9. 2011
    ..The findings demonstrate a significant protective effect against incident CAD in African American siblings of persons with premature CAD, with replication in a combination of two additional African American cohorts...
  23. ncbi Incidence of coronary artery disease in siblings of patients with premature coronary artery disease: 10 years of follow-up
    Dhananjay Vaidya
    Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Cardiol 100:1410-5. 2007
    ..In conclusion, in families with a history of premature CAD, the excess risk observed cannot be attributed to traditional risk factors, suggesting a major role for as yet undetermined genetic and other susceptibility factors...
  24. ncbi Predictors of low-density lipoprotein particle size in a high-risk African-American population
    Jeana L Benton
    Division of Cardiology, Medical School, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 95:1320-3. 2005
    ..77. Our data suggest that the standard lipid profile, primarily fasting triglyceride measurement, appears to be a useful surrogate for direct measurement of particle size in a high-risk African-American population...
  25. ncbi Women with a low Framingham risk score and a family history of premature coronary heart disease have a high prevalence of subclinical coronary atherosclerosis
    Erin D Michos
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am Heart J 150:1276-81. 2005
    ....
  26. ncbi Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development
    Marlene S Williams
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA
    Arterioscler Thromb Vasc Biol 30:2372-84. 2010
    ....
  27. ncbi Ageing, menopause, and ischaemic heart disease mortality in England, Wales, and the United States: modelling study of national mortality data
    Dhananjay Vaidya
    Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    BMJ 343:d5170. 2011
    ..To use changes in heart disease mortality rates with age to investigate the plausibility of attributing women's lower heart disease mortality than men to the protective effects of premenopausal sex hormones...
  28. ncbi Sex differences in platelet reactivity and response to low-dose aspirin therapy
    Diane M Becker
    Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    JAMA 295:1420-7. 2006
    ..Failure of aspirin to suppress platelet aggregation in women is one hypothesized mechanism...
  29. ncbi Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease
    Kiran Musunuru
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Circ Cardiovasc Genet 3:445-53. 2010
    ..To gain insights into the mechanisms underlying these associations, we hypothesized that single nucleotide polymorphisms (SNPs) in this region would be associated with platelet reactivity across multiple populations...
  30. ncbi Spiritual beliefs and barriers among managed care practitioners
    Jeanne McCauley
    Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
    J Relig Health 44:137-46. 2005
    ..Clinician education may overcome these barriers and improve ability to more fully meet their patients' expressed needs regarding spirituality and beliefs...
  31. ncbi Impact of a community-based multiple risk factor intervention on cardiovascular risk in black families with a history of premature coronary disease
    Diane M Becker
    Division of General Internal Medicine, Johns Hopkins Medical Institutions, 1830 E Monument St, Room 8028, Baltimore, MD 21287, USA
    Circulation 111:1298-304. 2005
    ..We tested a community-based multiple risk factor intervention (community-based care [CBC]) and compared it with "enhanced" primary care (EPC) to reduce CHD risk in high-risk black families...
  32. ncbi Familial occurrence of abnormalities of high-density lipoprotein cholesterol
    Brian G Kral
    The Johns Hopkins Sibling and Family Heart Study, Department of Medicine, The Johns Hopkins Medical Institutions, 1830 East Monument Street, Room 8033, Baltimore, MD 21205, USA
    J Clin Lipidol 1:31-40. 2007
    ....