Affiliation: Johns Hopkins University
- Evidence for parent of origin effect in late-onset Alzheimer diseaseSusan Spear Bassett
Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Med Genet 114:679-86. 2002....
- The role of test accuracy in predicting acceptance of genetic susceptibility testing for Alzheimer's diseaseSusan Spear Bassett
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Genet Test 8:120-6. 2004....
- Brain activation in offspring of AD cases corresponds to 10q linkageSusan Spear Bassett
Department of Psychiatry, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
Ann Neurol 58:142-6. 2005..These results suggest the possibility that activation patterns may prove useful as a preclinical quantitative trait related to the putative familial late-onset AD gene in this chromosome 10 region...
- Familial risk for Alzheimer's disease alters fMRI activation patternsSusan Spear Bassett
Department of Psychiatry, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Brain 129:1229-39. 2006....
- Further evidence of a maternal parent-of-origin effect on chromosome 10 in late-onset Alzheimer's diseaseSusan Spear Bassett
Department of Psychiatry, Johns Hopkins University, Baltimore, Maryland, USA
Am J Med Genet B Neuropsychiatr Genet 141:537-40. 2006....
- Gene expression reveals overlap between normal aging and Alzheimer's disease genesDimitrios Avramopoulos
McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University, School of Medicine, 733 N Broadway, Baltimore, MD, USA
Neurobiol Aging 32:2319.e27-34. 2011..This result supports an overlap between the biological processes of normal aging and susceptibility to AD and suggests that age related genes expression changes might increase the risk of developing AD...
- Physicians' propensity to offer genetic testing for Alzheimer's disease: results from a surveyGary A Chase
Department of Biostatistics and Research Epidemiology, Henry Ford Health Sciences Center, Johns Hopkins University School of Mediicne, Baltimore, MD, USA
Genet Med 4:297-303. 2002..Examine physician knowledge, preferences, and use of genetic tests for Alzheimer's disease (AD)...
- Altered fMRI activation during mental rotation in those at genetic risk for Alzheimer diseaseMichael A Yassa
Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medical Institutions, Johns Hopkins Hospital, Phipps 300, 600 North Wolfe Street, Baltimore, MD 21287, USA
Neurology 70:1898-904. 2008..This study was undertaken to examine differential functional MRI patterns in those at genetic risk for Alzheimer disease (AD), specifically investigating parietal lobe activation, a brain region with changes noted in the early stages of AD...
- A Bayesian hierarchical framework for spatial modeling of fMRI dataF DuBois Bowman
Department of Biostatistics, The Rollins School of Public Health, Emory University, USA
Neuroimage 39:146-56. 2008..We apply our Bayesian hierarchical model to two novel fMRI data sets: one considering inhibitory control in cocaine-dependent men and the second considering verbal memory in subjects at high risk for Alzheimer's disease...