Affiliation: Johns Hopkins University
Cloutier J, Thompson E, Cimino Mathews A, Rooper L, Matoso A, Argani P. Metastatic breast Cancer simulating well-differentiated neuroendocrine neoplasms of visceral organs. Hum Pathol. 2018;: pubmed publisher
..Diffuse IHC labeling for ER and GATA3 helps establish the correct diagnosis. ..
Argani P, Ladanyi M. Recent advances in pediatric renal neoplasia. Adv Anat Pathol. 2003;10:243-60 pubmed
..Together, these last two translocation-associated tumors represent a significant proportion of pediatric renal cell carcinomas. This review highlights each of these recent advances. ..
Argani P, Aulmann S, Karanjawala Z, Fraser R, Ladanyi M, Rodriguez M. Melanotic Xp11 translocation renal cancers: a distinctive neoplasm with overlapping features of PEComa, carcinoma, and melanoma. Am J Surg Pathol. 2009;33:609-19 pubmed publisher
Argani P. MiT family translocation renal cell carcinoma. Semin Diagn Pathol. 2015;32:103-13 pubmed publisher
..This review summarizes our current knowledge of these recently described RCCs. ..
Smith N, Epstein J, Parwani A, Netto G, Illei P, Powell K, et al
. Smooth muscle and adenoma-like renal tumor: a previously unreported variant of mixed epithelial stromal tumor or a distinctive renal neoplasm?. Hum Pathol. 2015;46:894-905 pubmed publisher
Kyker Snowman K, Erlanger Avigdor B, Nasim M, Cimino Mathews A, Wheelan S, Argani P, et al
. A primary breast cancer with distinct foci of estrogen receptor-alpha positive and negative cells derived from the same clonal origin as revealed by whole exome sequencing. Breast Cancer Res Treat. 2018;170:425-430 pubmed publisher
..Our results have implications for the evolution of breast cancers with mixed histologies, and how they might be best managed for optimal therapy. ..
Marchionni L, Hayashi M, Guida E, Ooki A, Munari E, Jabboure F, et al
. MicroRNA expression profiling of Xp11 renal cell carcinoma. Hum Pathol. 2017;67:18-29 pubmed publisher
..2 translocations involving the TFE3 gene. Our results might help understanding the molecular underpinning of Xp11 RCC, assisting in developing targeted treatments for this disease. ..
Argani P, Antonescu C, Illei P, Lui M, Timmons C, Newbury R, et al
. Primary renal neoplasms with the ASPL-TFE3 gene fusion of alveolar soft part sarcoma: a distinctive tumor entity previously included among renal cell carcinomas of children and adolescents. Am J Pathol. 2001;159:179-92 pubmed
..Finally, the finding of distinctive tumors being associated with balanced and unbalanced forms of the same translocation is to our knowledge, unprecedented...
Argani P, Hicks J, De Marzo A, Albadine R, Illei P, Ladanyi M, et al
. Xp11 translocation renal cell carcinoma (RCC): extended immunohistochemical profile emphasizing novel RCC markers. Am J Surg Pathol. 2010;34:1295-303 pubmed publisher
..Elevated expression of phosphorylated S6 in Xp11 translocation RCC suggests the mTOR pathway as an attractive potential therapeutic target for these neoplasms...