Research Topics
Genomes and GenesSpecies | Brian S ApplebySummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Rapidly progressive dementias and the treatment of human prion diseasesBrian S Appleby
Johns Hopkins University School of Medicine, Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Meyer 279, 600 N Wolfe St, Baltimore, MD 21287, USA
Expert Opin Pharmacother 12:1-12. 2011....
D178N, 129Val and N171S, 129Val genotype in a family with Creutzfeldt-Jakob diseaseBrian S Appleby
Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Dement Geriatr Cogn Disord 30:424-31. 2010..A mutation at codon 171 of the PRNP gene has been described in a family with a strong psychiatric history without prion disease...
Psychotropic medications and the treatment of human prion diseasesBrian S Appleby
Johns Hopkins University School of Medicine, Department of Psychiatry and Behavioral Sciences, Division of Geriatric Psychiatry and Neuropsychiatry, Baltimore, MD, USA
CNS Neurol Disord Drug Targets 8:353-62. 2009..There is a paucity of research examining the prevention of prion diseases in at risk populations (i.e. genetic and acquired prion diseases)...
Characteristics of established and proposed sporadic Creutzfeldt-Jakob disease variantsBrian S Appleby
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Arch Neurol 66:208-15. 2009....
Predictors of depression and anxiety in patients with intracranial neoplasmsBrian S Appleby
Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Neuropsychiatry Clin Neurosci 20:447-9. 2008..This study suggests that depression and anxiety are common comorbidities and that preexisting psychiatric disorders predispose to their occurrence within the neuro-oncology setting...
Trace and transference: therapy in a post-structuralist eraBrian S Appleby
Johns Hopkins Hospital, Baltimore, MD 21287, USA
Am J Psychother 62:103-15. 2008..Questions of how feelings and behaviors are constructed are also examined. In summary, a deconstructive therapeutic approach results in an array of freedom and possibilities...
Psychiatric and neuropsychiatric adverse events associated with deep brain stimulation: A meta-analysis of ten years' experienceBrian S Appleby
Department of Psychiatry, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Mov Disord 22:1722-8. 2007..Because of the high suicide rate, patients should be prescreened for suicide risk prior to DBS surgery. Additionally, patients should be monitored closely for suicidal behavior post-operatively...
Are anti-nuclear antibodies common in affective disorders? A review of the past 35 yearsBrian Appleby
The Johns Hopkins Hospital, Meyer 131, 600 North Wolfe St, Baltimore, MD 21287, USA
Psychosomatics 48:286-9. 2007....
Does the presentation of Creutzfeldt-Jakob disease vary by age or presumed etiology? A meta-analysis of the past 10 yearsBrian S Appleby
The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21287, USA
J Neuropsychiatry Clin Neurosci 19:428-35. 2007....
Clozapine for treatment-resistant agitation in dementiaHochang B Lee
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, 550 N Broadway, Suite 308, Baltimore, MD 21205, USA
J Geriatr Psychiatry Neurol 20:178-82. 2007..Overall, clozapine therapy seemed beneficial in treatment-resistant agitation in dementia patients...
Neuropsychiatric symptoms in MCI subtypes: the importance of executive dysfunctionPaul B Rosenberg
Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Int J Geriatr Psychiatry 26:364-72. 2011..Since dementia has been associated with a range of neuropsychiatric symptoms (NPS), we sought to examine the prevalence of NPS in MCI and its subtypes...
Scientific and ethical issues related to deep brain stimulation for disorders of mood, behavior, and thoughtPeter Rabins
Department of Psychiatry and Behavioral Sciences, Johns Hopkins Hospital, Baltimore, MD 21205, USA
Arch Gen Psychiatry 66:931-7. 2009....
A case of refractoriness to lithium therapy following its discontinuation in a previously responsive patientBrian Appleby
Johns Hopkins Hospital, Baltimore, MD 21287, USA
Harv Rev Psychiatry 14:330-2. 2006
Atypical neuroleptic malignant syndrome presenting as fever of unknown origin in the elderlyRyan C W Hall
Johns Hopkins Sinai Hospital, Department of Medicine, Baltimore, MD, USA
South Med J 98:114-7. 2005..A review of the medical literature is taken, focusing on diagnoses, prevalence, predisposing factors, pathophysiology, and current treatment approaches for NMS...
