Theodore P Abraham

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi request reprint Role of tissue Doppler and strain echocardiography in current clinical practice
    Theodore P Abraham
    Division of Cardiology, Johns Hopkins University, 600 N Wolfe St, Carnegie 568, Baltimore, MD 21287, USA
    Circulation 116:2597-609. 2007
  2. ncbi request reprint Myocardial dyssynchrony and resynchronization
    Theodore P Abraham
    Division of Cardiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Heart Fail Clin 2:179-92. 2006
  3. pmc The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance
    Radwa A Noureldin
    Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:17. 2012
  4. pmc Assessment of distribution and evolution of mechanical dyssynchrony in a porcine model of myocardial infarction by cardiovascular magnetic resonance
    Khaled Z Abd-Elmoniem
    Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:1. 2012
  5. pmc Comparison and effectiveness of regadenoson versus dipyridamole on stress electrocardiographic changes during positron emission tomography evaluation of patients with hypertrophic cardiomyopathy
    Paco E Bravo
    Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Am J Cardiol 110:1033-9. 2012
  6. doi request reprint Comparison of clinical presentation, left ventricular morphology, hemodynamics, and exercise tolerance in obese versus nonobese patients with hypertrophic cardiomyopathy
    Marco Canepa
    Division of Cardiology, Johns Hopkins University, Baltimore, Maryland Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institute of Health, Baltimore, Maryland Division of Cardiology, Research Center of Cardiovascular Biology, University of Genova, Italy
    Am J Cardiol 112:1182-9. 2013
  7. ncbi request reprint Utility of tissue Doppler and strain echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Kalpana R Prakasa
    Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland, USA
    Am J Cardiol 100:507-12. 2007
  8. pmc Cardiac resynchronization therapy corrects dyssynchrony-induced regional gene expression changes on a genomic level
    Andreas S Barth
    Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA
    Circ Cardiovasc Genet 2:371-8. 2009
  9. ncbi request reprint Comparison of novel echocardiographic parameters of right ventricular function with ejection fraction by cardiac magnetic resonance
    Jianwen Wang
    Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland, USA
    J Am Soc Echocardiogr 20:1058-64. 2007
  10. doi request reprint Relationship of delayed enhancement by magnetic resonance to myocardial perfusion by positron emission tomography in hypertrophic cardiomyopathy
    Paco E Bravo
    Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Circ Cardiovasc Imaging 6:210-7. 2013

Research Grants

  1. Modulation of Cardiac Mechanics in AL Amyloidosis
    Theodore Abraham; Fiscal Year: 2005
  2. Androgens and Myocardial Relaxation in the Aging Heart
    Theodore Abraham; Fiscal Year: 2007
  3. Development of a Hypertrophic Cardiomyopathy Consortium
    Theodore P Abraham; Fiscal Year: 2010
  4. Development of a Hypertrophic Cardiomyopathy Consortium
    Theodore P Abraham; Fiscal Year: 2010

Detail Information

Publications57

  1. ncbi request reprint Role of tissue Doppler and strain echocardiography in current clinical practice
    Theodore P Abraham
    Division of Cardiology, Johns Hopkins University, 600 N Wolfe St, Carnegie 568, Baltimore, MD 21287, USA
    Circulation 116:2597-609. 2007
  2. ncbi request reprint Myocardial dyssynchrony and resynchronization
    Theodore P Abraham
    Division of Cardiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Heart Fail Clin 2:179-92. 2006
  3. pmc The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance
    Radwa A Noureldin
    Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:17. 2012
    ..It is likely that integrating genetic advances with enhanced phenotypic characterization of HCM with novel CMR techniques will importantly improve our understanding of this complex disease...
  4. pmc Assessment of distribution and evolution of mechanical dyssynchrony in a porcine model of myocardial infarction by cardiovascular magnetic resonance
    Khaled Z Abd-Elmoniem
    Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA
    J Cardiovasc Magn Reson 14:1. 2012
    ..We sought to investigate the relationship between infarct and dyssynchrony post- myocardial infarct (MI), in a porcine model. Mechanical dyssynchrony post-MI is associated with left ventricular (LV) remodeling and increased mortality...
  5. pmc Comparison and effectiveness of regadenoson versus dipyridamole on stress electrocardiographic changes during positron emission tomography evaluation of patients with hypertrophic cardiomyopathy
    Paco E Bravo
    Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Am J Cardiol 110:1033-9. 2012
    ..Regadenoson is tolerated better than dipyridamole and is easier to administer. Vasodilator-induced ST-segment depression is a specific but nonsensitive marker for the prediction of abnormal rMP in patients with HC...
  6. doi request reprint Comparison of clinical presentation, left ventricular morphology, hemodynamics, and exercise tolerance in obese versus nonobese patients with hypertrophic cardiomyopathy
    Marco Canepa
    Division of Cardiology, Johns Hopkins University, Baltimore, Maryland Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institute of Health, Baltimore, Maryland Division of Cardiology, Research Center of Cardiovascular Biology, University of Genova, Italy
    Am J Cardiol 112:1182-9. 2013
    ..The association with increased outflow tract gradients has particular importance as contribution of obesity to the pressure gradients may influence clinical decisions in labile obstructive HC. ..
  7. ncbi request reprint Utility of tissue Doppler and strain echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Kalpana R Prakasa
    Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland, USA
    Am J Cardiol 100:507-12. 2007
    ..Peak RV systolic velocity <7.5 cm/s and peak RV strain <18% best identify patients with ARVD...
  8. pmc Cardiac resynchronization therapy corrects dyssynchrony-induced regional gene expression changes on a genomic level
    Andreas S Barth
    Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA
    Circ Cardiovasc Genet 2:371-8. 2009
    ..We hypothesized that such dyssynchrony also induces region-specific alterations in the myocardial transcriptome that are corrected by cardiac resynchronization therapy (CRT)...
  9. ncbi request reprint Comparison of novel echocardiographic parameters of right ventricular function with ejection fraction by cardiac magnetic resonance
    Jianwen Wang
    Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland, USA
    J Am Soc Echocardiogr 20:1058-64. 2007
    ..We sought to determine which echocardiographic variable or variables best correlated with RV ejection fraction (RVEF) by cardiac magnetic resonance...
  10. doi request reprint Relationship of delayed enhancement by magnetic resonance to myocardial perfusion by positron emission tomography in hypertrophic cardiomyopathy
    Paco E Bravo
    Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Circ Cardiovasc Imaging 6:210-7. 2013
    ..We investigated the relationship between DE on CMR and myocardial ischemia in hypertrophic cardiomyopathy...
  11. pmc Three-dimensional regional strain analysis in porcine myocardial infarction: a 3T magnetic resonance tagging study
    Sahar Soleimanifard
    Department of Electrical and Computer Engineering, Johns Hopkins University, 3400 N, Charles Street, Clark Hall 201, Baltimore, MD 21218, USA
    J Cardiovasc Magn Reson 14:85. 2012
    ..The aim of this study was to investigate the incremental value of CMR-based 3D strain and to test the hypothesis that 3D strain is superior to 1D or 2D strain analysis in the assessment of viability using a porcine model of infarction...
  12. pmc Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy
    Khalid Chakir
    Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Circulation 119:1231-40. 2009
    ..The mechanical impact of CRT is immediate and well documented, yet its long-term influences on myocyte function and adrenergic modulation that may contribute to its sustained benefits are largely unknown...
  13. doi request reprint Prevalence and pathophysiologic attributes of ventricular dyssynchrony in arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Laurens F Tops
    Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Am Coll Cardiol 54:445-51. 2009
    ..This study sought to investigate the prevalence and mechanisms underlying right ventricular (RV) dyssynchrony in arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) using tissue Doppler echocardiography (TDE)...
  14. doi request reprint Hypertrophy signaling pathways in experimental chronic aortic regurgitation
    Niels Thue Olsen
    Division of Cardiology, Johns Hopkins Medical Institutions, 600 N Wolfe St, Carnegie 568, Baltimore, MD, 21287, USA
    J Cardiovasc Transl Res 6:852-60. 2013
    ....
  15. doi request reprint Incidence and predictors of left atrial thrombus prior to catheter ablation of atrial fibrillation
    Daniel Scherr
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA
    J Cardiovasc Electrophysiol 20:379-84. 2009
    ..However, the incidence and predictors of LA thrombus detected with TEE have not been systematically examined in this setting...
  16. pmc Cardiac resynchronization by cardiosphere-derived stem cell transplantation in an experimental model of myocardial infarction
    Michael Bonios
    Johns Hopkins University, 720 Rutland Avenue, Baltimore, MD 21210, USA
    J Am Soc Echocardiogr 24:808-14. 2011
    ..The aim of this study was to examine the effects of CDC transplantation on regional function and dyssynchrony after MI...
  17. pmc Hyaluronic acid-human blood hydrogels for stem cell transplantation
    Connie Y Chang
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Biomaterials 33:8026-33. 2012
    ..01). HA-blood hydrogels are highly adhesive, biodegradable, promote CDC survival and increase cardiac function following epicardial application after myocardial infarction...
  18. doi request reprint The role of echocardiography in hemodynamic assessment in heart failure
    Jacob Abraham
    The Johns Hopkins University, Baltimore, MD 21287, USA
    Heart Fail Clin 5:191-208. 2009
    ..The importance of right heart failure and heart failure with preserved ejection fraction is increasingly recognized, and therefore the echocardiographic evaluation of these conditions is emphasized also...
  19. doi request reprint Pathophysiological mechanisms underlying ventricular dyssynchrony
    Alan Cheng
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Europace 11:v10-14. 2009
    ..Recent research has demonstrated that these biomolecular changes are amazingly reversed with cardiac resynchronization therapy, providing insight into how to target the therapy...
  20. pmc Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart
    Khalid Chakir
    Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Sci Transl Med 3:100ra88. 2011
    ..These results identify a key pathway that is triggered by restoring contractile synchrony and that may represent a new therapeutic approach for a broad population of HF patients...
  21. doi request reprint PET/CT assessment of symptomatic individuals with obstructive and nonobstructive hypertrophic cardiomyopathy
    Paco E Bravo
    Division of Nuclear Medicine, Department of Radiology, Johns Hopkins University, Baltimore, MD, USA
    J Nucl Med 53:407-14. 2012
    ..The aim of this study was to evaluate whether patients with obstruction, compared with nonobstructive HCM, demonstrate significant differences in PET parameters of microvascular function...
  22. pmc Electrophysiological consequences of dyssynchronous heart failure and its restoration by resynchronization therapy
    Takeshi Aiba
    Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Circulation 119:1220-30. 2009
    ..Cardiac resynchronization therapy (CRT) is widely applied in patients with heart failure and dyssynchronous contraction (DHF), but the electrophysiological consequences of CRT in heart failure remain largely unexplored...
  23. pmc Creatine kinase adenosine triphosphate and phosphocreatine energy supply in a single kindred of patients with hypertrophic cardiomyopathy
    M Roselle Abraham
    Cardiology Division, Department of Medicine, Johns Hopkins Hospital and Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Cardiol 112:861-6. 2013
    ..A lack of a relation between energetic and contractile abnormalities suggests the former result from the sarcomeric mutation and not a late consequence of mechanical dysfunction...
  24. ncbi request reprint New approach to intracardiac hemodynamic measurements in small animals: echo-guided percutaneous apical puncture
    Kristian Eskesen
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Ultrasound Med 31:1233-8. 2012
    ..Both of these techniques have disadvantages and are not conducive to repeated measurements. Therefore, the purpose of this study was to develop a new technique for measuring intracardiac hemodynamics...
  25. doi request reprint Reversal of global apoptosis and regional stress kinase activation by cardiac resynchronization
    Khalid Chakir
    Division of Cardiology, School of Medicine, Department of Biomedical Engineering, Johns Hopkins University Medical Institutions, Baltimore, MD 21205, USA
    Circulation 117:1369-77. 2008
    ..We hypothesized that cardiac resynchronization (CRT) from biventricular stimulation reverses such molecular abnormalities at the regional and global levels...
  26. doi request reprint Influence of atrial function and mechanical synchrony on LV hemodynamic status in heart failure patients on resynchronization therapy
    Hsin Yueh Liang
    Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    JACC Cardiovasc Imaging 4:691-8. 2011
    ..The aim of this study was to evaluate atrial and ventricular function in patients undergoing cardiac resynchronization therapy (CRT)...
  27. doi request reprint Echocardiography in hypertrophic cardiomyopathy: the role of conventional and emerging technologies
    Luis C Afonso
    Division of Cardiology, Wayne State University, Detroit, Michigan, USA
    JACC Cardiovasc Imaging 1:787-800. 2008
    ....
  28. doi request reprint Can quantitative regional myocardial dynamics contribute to the differential diagnosis of acute stress cardiomyopathy?
    Fatih Yalcin
    Department of Cardiology, Johns Hopkins University School of Medicine, Cardiovascular Imaging Center, Baltimore, USA
    Anadolu Kardiyol Derg 12:71-4. 2012
    ....
  29. ncbi request reprint Magnetic resonance imaging assessment of ventricular dyssynchrony: current and emerging concepts
    Albert C Lardo
    Division of Cardiology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    J Am Coll Cardiol 46:2223-8. 2005
    ....
  30. pmc Constitutive HIF-1α expression blunts the beneficial effects of cardiosphere-derived cell therapy in the heart by altering paracrine factor balance
    Michael Bonios
    Johns Hopkins University, Baltimore, MD 21205, USA
    J Cardiovasc Transl Res 4:363-72. 2011
    ..HIF-1α expression in CDCs blunted the beneficial functional effects of CDC transplantation, suggesting that paracrine factor balance may play an important role in cardiac regeneration...
  31. doi request reprint Image integration in catheter ablation of atrial fibrillation
    Laurens F Tops
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Europace 10:iii48-56. 2008
    ..In addition, factors that may affect the accuracy of the image integration process will be addressed. Finally, the effect of image integration on procedural characteristics and outcome will be reviewed...
  32. ncbi request reprint Feasibility and variability of three dimensional echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathy
    Kalpana R Prakasa
    Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA
    Am J Cardiol 97:703-9. 2006
    ..In conclusion, 3DE measurements of RV volumes and ejection fractions closely correlate with CMR values and may be useful in the follow-up of patients with ARVD/C...
  33. pmc Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice
    Theodore P Abraham
    Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA
    Cardiovasc Res 82:84-92. 2009
    ....
  34. pmc Electromechanical relationship in hypertrophic cardiomyopathy
    Xiaoping Lin
    Division of Cardiology, Johns Hopkins University School of Medicine, 720 Rutland Ave, Ross 871, Baltimore, MD 21201, USA
    J Cardiovasc Transl Res 6:604-15. 2013
    ..LVH and repolarization abnormalities on surface EKG are markers of impaired systolic and diastolic mechanics in HCM. ..
  35. pmc Contribution of central adiposity to left ventricular diastolic function (from the Baltimore Longitudinal Study of Aging)
    Marco Canepa
    Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    Am J Cardiol 109:1171-8. 2012
    ..The effect of visceral adiposity on LV diastolic dysfunction would benefit from confirmation in longitudinal studies...
  36. doi request reprint Diagnostic accuracy of arterial phase 64-slice multidetector CT angiography for left atrial appendage thrombus in patients undergoing atrial fibrillation ablation
    Ilan Gottlieb
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
    J Cardiovasc Electrophysiol 19:247-51. 2008
    ..Multidetector CT (MDCT) is used prior to atrial fibrillation ablation (AFA) to anatomically guide ablation procedures. Whether 64-slice MDCT also can be used to diagnose left atrial thrombus is not known...
  37. ncbi request reprint Tricuspid annular displacement predicts survival in pulmonary hypertension
    Paul R Forfia
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins Hospital, Asthma and Allergy Center, Baltimore, MD 21224, USA
    Am J Respir Crit Care Med 174:1034-41. 2006
    ..Right ventricular (RV) function is an important determinant of prognosis in pulmonary hypertension. However, noninvasive assessment of the RV function is often limited by complex geometry and poor endocardial definition...
  38. ncbi request reprint TGFbeta inducible early gene-1 (TIEG1) and cardiac hypertrophy: Discovery and characterization of a novel signaling pathway
    Nalini M Rajamannan
    Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    J Cell Biochem 100:315-25. 2007
    ..We present evidence implicating TIEG and possibly its target gene, Pttg1, in the development of cardiac hypertrophy in the TIEG null mouse...
  39. ncbi request reprint Two-dimensional acoustic pattern derived strain parameters closely correlate with one-dimensional tissue Doppler derived strain measurements
    Karen M Modesto
    Division of Cardiology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Eur J Echocardiogr 7:315-21. 2006
    ..Novel 2D-SE software allows semi-automated strain measurements and increased averaging capabilities optimizing signal-noise ratio...
  40. pmc Stress induced hypertensive response: should it be evaluated more carefully?
    Nagehan Kucukler
    Johns Hopkins Medical Institutions, Department of Cardiology, Baltimore, MD, USA
    Cardiovasc Ultrasound 9:22. 2011
    ....
  41. ncbi request reprint Resolution of left atrial appendage thrombus by 64-detector CT scan
    Ilan Gottlieb
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 19:103. 2008
  42. ncbi request reprint Strain rate imaging for assessment of regional myocardial function: results from a clinical model of septal ablation
    Theodore P Abraham
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn 55905, USA
    Circulation 105:1403-6. 2002
    ..We examined regional myocardial function using TDI and SRI in a unique clinical model of a small, discrete myocardial infarction...
  43. ncbi request reprint Analysis of postsystolic myocardial thickening work in selective myocardial layers during progressive myocardial ischemia
    Jianwen Wang
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Am Soc Echocardiogr 19:1102-11. 2006
    ..We calculated systolic and postsystolic regional myocardial work index (RMWi) in subendocardial and subepicardial layers of myocardium supplied by a slowly occluding coronary artery...
  44. ncbi request reprint Myocardial contractility by strain echocardiography: comparison with physiological measurements in an in vitro model
    Theodore P Abraham
    Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Am J Physiol Heart Circ Physiol 285:H2599-604. 2003
    ..There was no bias with SR measurements during hypoxia or with epsilon measurements. SE closely tracks standard physiological parameters of regional contractile function, such as SV and delta L, under conditions of varying afterload...
  45. ncbi request reprint Strain and strain rate echocardiography
    Cristina Pislaru
    Department of Physiology and Biophysics, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Curr Opin Cardiol 17:443-54. 2002
    ..This article reviews basic principles and current experimental and clinical applications of strain and strain rate echocardiography...
  46. ncbi request reprint Time to onset of regional relaxation: feasibility, variability and utility of a novel index of regional myocardial function by strain rate imaging
    Theodore P Abraham
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905
    J Am Coll Cardiol 39:1531-7. 2002
    ..This study sought to prospectively establish the feasibility and variability of T(R) in healthy volunteers (CONTROL) and to examine its utility in patients with inducible ischemia (PATIENT)...
  47. ncbi request reprint Strain rate and strain: a step-by-step approach to image and data acquisition
    Gregory Gilman
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Am Soc Echocardiogr 17:1011-20. 2004
    ..This article provides the echocardiographer with a step-by-step approach...
  48. ncbi request reprint Left atrial myopathy in cardiac amyloidosis: implications of novel echocardiographic techniques
    Karen M Modesto
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN, USA
    Eur Heart J 26:173-9. 2005
    ..To assess left atrial (LA) function and determine the prevalence of LA dysfunction in AL amyloidosis (AL) using conventional and strain echocardiography...
  49. ncbi request reprint Delayed onset of subendocardial diastolic thinning at rest identifies hypoperfused myocardium
    Jianwen Wang
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Circulation 111:2943-50. 2005
    ..We hypothesized that delayed onset of subendocardial diastolic thinning will functionally identify regionally hypoperfused resting myocardium...
  50. ncbi request reprint Speckle-derived strain a better tool for quantification of stress echocardiography?
    Theodore P Abraham
    J Am Coll Cardiol 51:158-60. 2008
  51. doi request reprint Evidence of impaired left ventricular systolic function by Doppler myocardial imaging in patients with systemic amyloidosis and no evidence of cardiac involvement by standard two-dimensional and Doppler echocardiography
    Diego Bellavia
    Cardiovascular Division, Mayo Clinic and Foundation, Rochester, MN, USA
    Am J Cardiol 101:1039-45. 2008
    ..This distinction was not apparent from peak longitudinal sTVI or from radial or circumferential sSI or sSR...
  52. ncbi request reprint Beta-blocker therapy induces ventricular resynchronization in dilated cardiomyopathy with narrow QRS complex
    Yasuhiko Takemoto
    Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, Osaka, Japan
    J Am Coll Cardiol 49:778-83. 2007
    ..We sought to evaluate the effects of beta-blocker therapy on regional and global myocardial mechanics in addition to ventricular synchrony in patients with heart failure and normal QRS by using tissue Doppler and strain echocardiography...
  53. ncbi request reprint Two-dimensional strain--a Doppler-independent ultrasound method for quantitation of regional deformation: validation in vitro and in vivo
    Josef Korinek
    Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    J Am Soc Echocardiogr 18:1247-53. 2005
    ..We compared strains measured in vitro and in vivo by 2DSE with those obtained by sonomicrometry...
  54. ncbi request reprint Right ventricular function in asymptomatic individuals with a systemic right ventricle
    J Martijn Bos
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
    J Am Soc Echocardiogr 19:1033-7. 2006
    ..In congenital heart defects where the morphologic right ventricle (RV) supports the systemic circulation, RV failure is common yet develops gradually. We hypothesized that patients who are asymptomatic may have unrecognized RV dysfunction...
  55. ncbi request reprint Usefulness of two-dimensional speckle strain for evaluation of left ventricular diastolic deformation in patients with coronary artery disease
    Hsin Yueh Liang
    Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Cardiol 98:1581-6. 2006
    ..Altered diastolic deformation at rest identifies regions subtended by > or =70% coronary stenosis with high specificity...
  56. ncbi request reprint Increased right ventricular afterload induces postsystolic thickening of the ventricular septum in nonischemic hearts
    Stig Urheim
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    J Am Soc Echocardiogr 18:839-43. 2005
    ..We aimed to assess whether myocardial postsystolic thickening (PST) can be induced by an acute increase in right ventricular (RV) afterload and, thus, demonstrate that PST may have a nonischemic cause...
  57. ncbi request reprint Impact of arterial load and loading sequence on left ventricular tissue velocities in humans
    Barry A Borlaug
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 50:1570-7. 2007
    ..The aim of this study was to examine the relationship between individual components of left ventricular (LV) afterload and tissue Doppler echocardiography (TDE) velocities in humans...

Research Grants5

  1. Modulation of Cardiac Mechanics in AL Amyloidosis
    Theodore Abraham; Fiscal Year: 2005
    ..The long-term goal of this research is to better understand the factors that influence the development of cardiac dysfunction in AL with the aim of optimizing treatment strategies to improve clinical outcomes in AL patients. ..
  2. Androgens and Myocardial Relaxation in the Aging Heart
    Theodore Abraham; Fiscal Year: 2007
    ..Most importantly, potential direct clinical benefits of this research include early detection, improved and novel therapy, and better clinical outcomes for age-related diastolic dysfunction. ..
  3. Development of a Hypertrophic Cardiomyopathy Consortium
    Theodore P Abraham; Fiscal Year: 2010
    ....
  4. Development of a Hypertrophic Cardiomyopathy Consortium
    Theodore P Abraham; Fiscal Year: 2010
    ....