Susan C Abraham

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. pmc Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas : frequent alterations in the APC/beta-catenin pathway and chromosome 11p
    S C Abraham
    Division of Gastrointestinal Liver Pathology, The Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Pathol 159:1619-27. 2001
  2. ncbi request reprint Hyperplastic polyps of the esophagus and esophagogastric junction: histologic and clinicopathologic findings
    S C Abraham
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Surg Pathol 25:1180-7. 2001
  3. pmc Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway
    Susan C Abraham
    Department of Pathology, Division of GI LiverPathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Pathol 160:953-62. 2002
  4. ncbi request reprint Upper gastrointestinal tract injury in patients receiving kayexalate (sodium polystyrene sulfonate) in sorbitol: clinical, endoscopic, and histopathologic findings
    S C Abraham
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Surg Pathol 25:637-44. 2001
  5. ncbi request reprint Hyperplastic polyps of the stomach: associations with histologic patterns of gastritis and gastric atrophy
    S C Abraham
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Surg Pathol 25:500-7. 2001
  6. pmc Sporadic fundic gland polyps: common gastric polyps arising through activating mutations in the beta-catenin gene
    S C Abraham
    Department of Pathology, Division of Gastroenterology, The Johns Hopkins University School of Medicine, Ross Building, Room 632, 720 Rutland Ave, Baltimore, MD 21205 2196, USA
    Am J Pathol 158:1005-10. 2001
  7. ncbi request reprint Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas
    Jae Hyuk Lee
    Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Oncogene 23:4646-54. 2004
  8. ncbi request reprint Hepatic adenomas: analysis of sex steroid receptor status and the Wnt signaling pathway
    Michael Torbenson
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Mod Pathol 15:189-96. 2002
  9. ncbi request reprint Molecular and immunohistochemical analysis of intraductal papillary neoplasms of the biliary tract
    Susan C Abraham
    Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 34:902-10. 2003
  10. pmc Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations
    Susan C Abraham
    Department of Pathology, Division of Gastrointestinal Liver Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Pathol 160:1361-9. 2002

Detail Information

Publications74

  1. pmc Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas : frequent alterations in the APC/beta-catenin pathway and chromosome 11p
    S C Abraham
    Division of Gastrointestinal Liver Pathology, The Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Pathol 159:1619-27. 2001
    ..In addition, pancreatoblastoma may represent an extracolonic manifestation of FAP...
  2. ncbi request reprint Hyperplastic polyps of the esophagus and esophagogastric junction: histologic and clinicopathologic findings
    S C Abraham
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Surg Pathol 25:1180-7. 2001
    ..Careful clinical history and biopsy of the nonpolypoid mucosa are essential for determining the clinicopathologic context in which the polyps have developed...
  3. pmc Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway
    Susan C Abraham
    Department of Pathology, Division of GI LiverPathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Pathol 160:953-62. 2002
    ..These results indicate that ACCs are genetically distinct from pancreatic ductal adenocarcinomas, but some cases contain genetic alterations common to histologically similar pancreatoblastomas...
  4. ncbi request reprint Upper gastrointestinal tract injury in patients receiving kayexalate (sodium polystyrene sulfonate) in sorbitol: clinical, endoscopic, and histopathologic findings
    S C Abraham
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Surg Pathol 25:637-44. 2001
    ..Recognition of Kayexalate crystals in histologic sections as a marker for sorbitol-induced mucosal damage may aid in establishing the correct diagnosis for clinically or endoscopically misleading lesions...
  5. ncbi request reprint Hyperplastic polyps of the stomach: associations with histologic patterns of gastritis and gastric atrophy
    S C Abraham
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Surg Pathol 25:500-7. 2001
    ..These results indicate a strong association between various forms of gastritis and the development of hyperplastic polyps and further emphasize the importance of biopsy of the nonpolypoid gastric mucosa during endoscopic examination...
  6. pmc Sporadic fundic gland polyps: common gastric polyps arising through activating mutations in the beta-catenin gene
    S C Abraham
    Department of Pathology, Division of Gastroenterology, The Johns Hopkins University School of Medicine, Ross Building, Room 632, 720 Rutland Ave, Baltimore, MD 21205 2196, USA
    Am J Pathol 158:1005-10. 2001
    ..Sporadic FGPs are therefore the only lesions of the gastrointestinal tract to demonstrate beta-catenin mutations while lacking dysplastic morphology...
  7. ncbi request reprint Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas
    Jae Hyuk Lee
    Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030, USA
    Oncogene 23:4646-54. 2004
    ..Methylation of the p16 gene may contribute to the malignant transformation of gastric precursor lesions...
  8. ncbi request reprint Hepatic adenomas: analysis of sex steroid receptor status and the Wnt signaling pathway
    Michael Torbenson
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Mod Pathol 15:189-96. 2002
    ..Activation of the Wnt signaling pathway appears to be important in a subset of hepatic adenomas but does not result from common beta-catenin or APC mutations and does not appear to be directly linked to hormonal receptor status...
  9. ncbi request reprint Molecular and immunohistochemical analysis of intraductal papillary neoplasms of the biliary tract
    Susan C Abraham
    Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 34:902-10. 2003
    ..Finally, the frequency of allelic loss on 18q suggests that a locus on 18q is involved in the molecular pathogenesis of biliary IPNs, but this locus is not DPC4...
  10. pmc Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations
    Susan C Abraham
    Department of Pathology, Division of Gastrointestinal Liver Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Am J Pathol 160:1361-9. 2002
    ..Overexpression of p53 was limited to only 3 of 19 (15.8%) SPTs. These results emphasize the two distinct, divergent genetic pathways of neoplastic progression in pancreatic ductal and nonductal neoplasms...
  11. ncbi request reprint Genetic alterations in gastric adenomas of intestinal and foveolar phenotypes
    Susan C Abraham
    Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Mod Pathol 16:786-95. 2003
    ..Although intestinal-type and foveolar-type gastric adenomas display divergent biologic behavior, the specific genetic events accounting for these differences in morphology and biologic behavior are unclear...
  12. doi request reprint Significance of central perivenulitis in pediatric liver transplantation
    Susan C Abraham
    Department of Pathology, M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg Pathol 32:1479-88. 2008
    ..CP is most common in conjunction with portal ACR, where it carries a significant risk for the development of zone 3 fibrosis and a trend toward the development of ductopenic chronic rejection...
  13. ncbi request reprint Frequent CpG island methylation in sporadic and syndromic gastric fundic gland polyps
    Susan C Abraham
    Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Pathol 122:740-6. 2004
    ..87). Epigenetic alterations involving methylation of CpG islands might have a role in the development of some FGPs, particularly those with a PPI effect. They do not account for the presence or absence of a dysplastic phenotype in FGPs...
  14. doi request reprint Duplicated muscularis mucosae invasion has similar risk of lymph node metastasis and recurrence-free survival as intramucosal esophageal adenocarcinoma
    Jeannelyn S Estrella
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA
    Am J Surg Pathol 35:1045-53. 2011
    ..EAC invasion into the space between duplicated MM confers a similar risk of lymph node metastasis and recurrence as those of intramucosal EAC, and LVI is the best predictor of lymph node status and RFS in pT1 EAC...
  15. ncbi request reprint Sporadic fundic gland polyposis: a clinical, histological, and molecular analysis
    Michael Torbenson
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland, USA
    Mod Pathol 15:718-23. 2002
    ..The fundic gland polyps were histologically and genetically identical to single sporadic fundic gland polyps and demonstrated frequent somatic activating mutations in exon 3 of the beta-catenin gene...
  16. pmc Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma
    Jae Hyuk Lee
    Department of Pathology, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Am J Pathol 161:611-8. 2002
    ..Gastric adenomas or dysplasias without APC mutations but with or without MSI may have a different biological behavior, and are precursors of intestinal-type of gastric adenocarcinomas...
  17. pmc Sporadic fundic gland polyps with epithelial dysplasia : evidence for preferential targeting for mutations in the adenomatous polyposis coli gene
    Susan C Abraham
    Department of Pathology, Division of Gastrointestinal Liver Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Pathol 161:1735-42. 2002
    ..The lack of microsatellite instability in FGPs in this study and of K-ras mutations in a previous study suggests that secondary genetic alterations are rare in both dysplastic and nondysplastic FGPs...
  18. pmc Results of pancreaticoduodenectomy for lymphoplasmacytic sclerosing pancreatitis
    Jeffrey M Hardacre
    Department of Surgery, The Johns Hopkins Hospital, 600 N Wolfe Street, Baltimore, MD 21287 4688, USA
    Ann Surg 237:853-8; discussion 858-9. 2003
    ....
  19. ncbi request reprint Diffuse lymphoplasmacytic chronic cholecystitis is highly specific for extrahepatic biliary tract disease but does not distinguish between primary and secondary sclerosing cholangiopathy
    Susan C Abraham
    Department of Pathology, Hilton 11 Mayo Clinic, 220 First Street SW, Rochester, MN, USA
    Am J Surg Pathol 27:1313-20. 2003
    ..These results suggest that a pattern of diffuse lymphoplasmacytic chronic cholecystitis is highly specific for extrahepatic biliary tract disease but does not distinguish between primary and secondary cholangiopathies...
  20. doi request reprint Paget cells in the esophagus: assessment of their histopathologic features and near-universal association with underlying esophageal adenocarcinoma
    Susan C Abraham
    Department of Pathology, M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg Pathol 32:1068-74. 2008
    ..A commonality among cases with Paget cells is the presence of focal or diffuse, poorly differentiated adenocarcinoma with discohesive cells. E-cadherin alterations seem to play a less significant role...
  21. doi request reprint Precancerous bile duct pathology in end-stage primary sclerosing cholangitis, with and without cholangiocarcinoma
    Jason T Lewis
    Division of Anatomic Pathology, Department of Pathology, DeKalb Medical Center, Decatur, GA 30033, USA
    Am J Surg Pathol 34:27-34. 2010
    ..Dysplasia, however, is generally confined to large and septal-size bile ducts and its presence may not be recognized unless multiple sections specifically targeted to the biliary tree are examined...
  22. ncbi request reprint Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarrays
    Sharon L Swierczynski
    Department of Pathology, The Johns Hopkinds University School of Medicine, Baltimore, MD 21231, USA
    Hum Pathol 35:357-66. 2004
    ..Therefore, these markers are potentially useful in developing diagnostic tests and treatment paradigms for tumors involving the biliary system...
  23. ncbi request reprint Lymphoplasmacytic chronic cholecystitis and biliary tract disease in patients with lymphoplasmacytic sclerosing pancreatitis
    Susan C Abraham
    Department of Pathology, Hilton 11, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Surg Pathol 27:441-51. 2003
    ....
  24. doi request reprint Pyloric gland adenoma: an entity distinct from gastric foveolar type adenoma
    Zong Ming Chen
    Department of Pathology, Johns Hopkins University, Baltimore, MD 21231 2410, USA
    Am J Surg Pathol 33:186-93. 2009
    ..Despite its bland histologic appearance, it is much more likely to be accompanied by background IM and autoimmune gastritis and can evolve into invasive adenocarcinoma displaying pyloric gland differentiation...
  25. doi request reprint Patchy distribution of pathologic abnormalities in autoimmune pancreatitis: implications for preoperative diagnosis
    Vishal S Chandan
    Department of Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 32:1762-9. 2008
    ..IgG4 immunostaining of apparently negative biopsies may be helpful, but only in a small minority of cases...
  26. ncbi request reprint Oxyntic mucosa pseudopolyps: a presentation of atrophic autoimmune gastritis
    Alyssa M Krasinskas
    Department of Pathology, University of Pennsylvania Medical Center, Philadelphia, USA
    Am J Surg Pathol 27:236-41. 2003
    ..Although a limited number of previous studies have suggested this type of polypoid presentation may represent "early" atrophic gastritis, its persistence in three of our patients argues against this hypothesis...
  27. doi request reprint Mucosal colonization by metastatic carcinoma in the gastrointestinal tract: a potential mimic of primary neoplasia
    Jeannelyn S Estrella
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg Pathol 35:563-72. 2011
    ..In situ growth and presence of an apparent adenoma cannot be taken as prima facie evidence of a primary neoplasm...
  28. ncbi request reprint CD44 loss in gastric stromal tumors as a prognostic marker
    Elizabeth Montgomery
    Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Surg Pathol 28:168-77. 2004
    ..Thus, the prognostic value of CD44s and isoform expression in GIST were evaluated by immunohistochemistry of tissue microarrays...
  29. ncbi request reprint "Seedling" mesenchymal tumors (gastrointestinal stromal tumors and leiomyomas) are common incidental tumors of the esophagogastric junction
    Susan C Abraham
    Division of Anatomic Pathology, Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 31:1629-35. 2007
    ..The common occurrence of microscopic GISTs compared with the rarity of clinically manifest and malignant esophagogastric GISTs suggests that additional genetic or epigenetic alterations must happen for neoplastic progression...
  30. ncbi request reprint Tumor suppressor gene hypermethylation as a predictor of gastric stromal tumor behavior
    Michael G House
    Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD 21231 1000, USA
    J Gastrointest Surg 7:1004-14; discussion 1014. 2003
    ..This study supports the methylation status of E-cadherin as a prognostic marker for early GIST recurrence and survival...
  31. ncbi request reprint Epidermal growth factor receptor, p53 mutation, and pathological response predict survival in patients with locally advanced esophageal cancer treated with preoperative chemoradiotherapy
    Michael K Gibson
    Division of Medical Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231, USA
    Clin Cancer Res 9:6461-8. 2003
    ..This study evaluates the role of clinical and cellular markers in predicting CR and OS in patients with esophageal cancer...
  32. ncbi request reprint Excellent interobserver agreement on grading the extent of residual carcinoma after preoperative chemoradiation in esophageal and esophagogastric junction carcinoma: a reliable predictor for patient outcome
    Tsung Teh Wu
    Department of Pathology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Am J Surg Pathol 31:58-64. 2007
    ..The extent of residual carcinoma is a reliable and reproducible predictor of survival; this grading system may allow a novel and early means of comparing outcomes after different neoadjuvant treatment regimens...
  33. doi request reprint The prevalence and natural history of untreated isolated central perivenulitis in adult allograft livers
    Alyssa M Krasinskas
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213 2546, USA
    Liver Transpl 14:625-32. 2008
    ..In summary, "transplant-associated" isolated CP occurs in 28% of adult patients, early CP is predictive of late CP, and late CP (often present as isolated CP) is associated with long-term liver injury in some patients...
  34. doi request reprint Expression of melanoma antigens in epithelioid gastrointestinal stromal tumors: a potential diagnostic pitfall
    Mehmet L Guler
    Department of Pathology, Johns Hopkins University, Baltimore, MD 21231, USA
    Arch Pathol Lab Med 132:1302-6. 2008
    ..Most gastric gastrointestinal stromal tumors (GISTs) express CD117/c-kit, as do a subset of metastatic melanomas, leading to a diagnostic dilemma in some cases...
  35. doi request reprint Histologic abnormalities are common in protocol liver allograft biopsies from patients with normal liver function tests
    Susan C Abraham
    Department of Pathology, M D Anderson Cancer Center, Houston, TX, USA
    Am J Surg Pathol 32:965-73. 2008
    ....
  36. ncbi request reprint Eosinophilic pancreatitis and increased eosinophils in the pancreas
    Susan C Abraham
    Department of Pathology, Hilton 11, Mayo Clinic, 220 First Street SW, Rochester, MN 55905, USA
    Am J Surg Pathol 27:334-42. 2003
    ..True eosinophilic pancreatitis, although a fascinating clinicopathologic entity, is one of the rarest causes of pancreatic eosinophilia...
  37. ncbi request reprint Pancreaticoduodenectomy (Whipple resections) in patients without malignancy: are they all 'chronic pancreatitis'?
    Susan C Abraham
    Department of Pathology, Mayo Clinic, Rochester, Minnesota, 55905, USA
    Am J Surg Pathol 27:110-20. 2003
    ..2%) and reveal a diverse group of clinicopathologically distinctive pancreatic and biliary tract disease...
  38. ncbi request reprint Microsatellite instability in intraductal papillary neoplasms of the biliary tract
    Susan C Abraham
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Mod Pathol 15:1309-17. 2002
    ....
  39. doi request reprint Metastatic neuroendocrine tumour in the breast: a potential mimic of in-situ and invasive mammary carcinoma
    Kyle D Perry
    Division of Anatomic Pathology, Department of Pathology, Mayo Clinic, Rochester, MN, USA
    Histopathology 59:619-30. 2011
    ....
  40. ncbi request reprint Colchicine effect in a colonic hyperplastic polyp. A lesion mimicking serrated adenoma
    Michael Torbenson
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205 2196, USA
    Arch Pathol Lab Med 126:615-7. 2002
    ..Distinguishing between hyperplastic polyp and serrated adenoma is important because of the different management implications and the increased potential for neoplastic progression in the latter...
  41. ncbi request reprint Fibromatosis of the breast and mutations involving the APC/beta-catenin pathway
    Susan C Abraham
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205 2196, USA
    Hum Pathol 33:39-46. 2002
    ..The spectrum of beta-catenin and APC alterations is similar to that described for desmoid tumors of the abdomen, paraspinal region, and extremities...
  42. ncbi request reprint Atrophic autoimmune pangastritis: A distinctive form of antral and fundic gastritis associated with systemic autoimmune disease
    Dragan Jevremovic
    Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 30:1412-9. 2006
    ..The development of multifocal low-grade dysplasia in 1 patient, a 19-year-old woman, suggests that this condition might have neoplastic potential...
  43. ncbi request reprint Bile duct dysplasia in the setting of chronic hepatitis C and alcohol cirrhosis
    Michael Torbenson
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
    Am J Surg Pathol 31:1410-3. 2007
    ..Alcohol also seems to be a risk factor. The dysplastic changes are multifocal, involve septal sized bile ducts, and are typically papillary...
  44. ncbi request reprint Beta-catenin immunohistochemistry separates mesenteric fibromatosis from gastrointestinal stromal tumor and sclerosing mesenteritis
    Elizabeth Montgomery
    Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
    Am J Surg Pathol 26:1296-301. 2002
    ..beta-Catenin staining identifies lesions that are, instead, mesenteric fibromatoses...
  45. ncbi request reprint Gastric adenomas: intestinal-type and gastric-type adenomas differ in the risk of adenocarcinoma and presence of background mucosal pathology
    Susan C Abraham
    Divison of Gastrointerstinal Liver Pathology, Department of Pahology, Johns Hopkins University School of Medicine, Baltimeore, Maryland
    Am J Surg Pathol 26:1276-85. 2002
    ..In any individual patient complete removal of the adenoma should be performed, and thorough biopsy of the surrounding gastric mucosa is essential to understand the clinicopathologic context of the adenoma...
  46. pmc Frequent beta-catenin mutations in juvenile nasopharyngeal angiofibromas
    S C Abraham
    Department of Pathology, Division of Gastroenterology, The Johns Hopkins University School of Medicine, 720 Rutland Ave, Baltimore, MD 21205-2196, USA
    Am J Pathol 158:1073-8. 2001
    ..The immunohistochemical localization of beta-catenin only to the nuclei of stromal cells further suggests that the stromal cells, rather than endothelial cells, are the neoplastic cells of JNAs...
  47. ncbi request reprint Superficial fibromatoses are genetically distinct from deep fibromatoses
    E Montgomery
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Mod Pathol 14:695-701. 2001
    ..This difference may account inpart for their divergent clinical manifestations despite their morphologic resemblance to deep fibromatoses...
  48. ncbi request reprint Endoscopic findings predict the histologic diagnosis in gastrointestinal graft-versus-host disease
    M Cruz-Correa
    Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Endoscopy 34:808-13. 2002
    ..We performed a study to determine the diagnostic accuracy of macroscopic endoscopy findings in the diagnosis of acute and chronic histologically proven gastrointestinal GvHD (GI-GvHD)...
  49. ncbi request reprint Clinicopathologic and molecular analysis of high-grade dysplasia and early adenocarcinoma in short- versus long-segment Barrett esophagus
    B Nobukawa
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205 2196, USA
    Hum Pathol 32:447-54. 2001
    ..These results suggest that both HGD and early adenocarcinoma in SSBE and LSBE may occur through similar genetic alterations, whereas there are some clinicopathologic differences between SSBE and LSBE. HUM PATHOL..
  50. doi request reprint Rosai-Dorfman disease confined to the breast
    Jerzy J Morkowski
    Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Ann Diagn Pathol 14:81-7. 2010
    ....
  51. ncbi request reprint Glycogen pseudoground glass change in hepatocytes
    Joshua Wisell
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA
    Am J Surg Pathol 30:1085-90. 2006
    ..The changes are generally seen in the background of mild chronic hepatitis with mild or no fibrosis. Glycogen pseudoground glass change can resolve, but may also persist for years...
  52. ncbi request reprint Remission of severe autoimmune enteropathy after treatment with high-dose cyclophosphamide
    Maria M Oliva-Hemker
    Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21187 2631, USA
    J Pediatr Gastroenterol Nutr 36:639-43. 2003
  53. ncbi request reprint Colonic spirochetosis in children and adults
    Ayman Koteish
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Clin Pathol 120:828-32. 2003
    ..While treatment information remains limited, treatment can lead to resolution of symptoms in some cases...
  54. ncbi request reprint Autoimmune gastritis: distinct histological and immunohistochemical findings before complete loss of oxyntic glands
    Michael Torbenson
    Division of Gastrointestinal Liver Pathology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Mod Pathol 15:102-9. 2002
    ....
  55. doi request reprint High-level microsatellite instability in appendiceal carcinomas
    Melissa W Taggart
    Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 37:1192-200. 2013
    ....
  56. ncbi request reprint Giant fibrovascular polyp of the esophagus. A lesion causing upper airway obstruction and syncope
    Matthew R Fries
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Arch Pathol Lab Med 127:485-7. 2003
    ..Despite their large size, giant fibrovascular polyps should be recognized radiologically and pathologically as benign lesions. However, they can result in significant morbidity...
  57. ncbi request reprint Alendronate-associated esophageal injury: pathologic and endoscopic features
    S C Abraham
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 2196, USA
    Mod Pathol 12:1152-7. 1999
    ..Recognition of alendronate-associated erosive or ulcerative esophagitis, particularly in postmenopausal women, and communication of this possibility to the clinician can improve patient care...
  58. ncbi request reprint Colchicine toxicity: distinct morphologic findings in gastrointestinal biopsies
    C A Iacobuzio-Donahue
    Division of Gastrointestinal/Liver Pathology, Department of Pathology, Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland 21205-2196, USA
    Am J Surg Pathol 25:1067-73. 2001
    ..Recognition of these features is important because colchicine toxicity can be fatal if undiagnosed clinically...
  59. ncbi request reprint Prevalence and risk factors for gallbladder neoplasia in patients with primary sclerosing cholangitis: evidence for a metaplasia-dysplasia-carcinoma sequence
    Jason T Lewis
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 31:907-13. 2007
    ..The strong correlation between gallbladder dysplasia/adenocarcinoma and bile duct dysplasia/CC supports the concept of a neoplastic "field effect" along the intrahepatic and extrahepatic biliary tract in PSC...
  60. doi request reprint Muscularis mucosae duplication and the musculo-fibrous anomaly in endoscopic mucosal resections for barrett esophagus: implications for staging of adenocarcinoma
    Jason T Lewis
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 32:566-71. 2008
    ....
  61. ncbi request reprint Duplication of the muscularis mucosae in Barrett esophagus: an underrecognized feature and its implication for staging of adenocarcinoma
    Susan C Abraham
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA
    Am J Surg Pathol 31:1719-25. 2007
    ..The 17% rate of angiolymphatic invasion and 10% rate of lymph node metastases in our patients with invasion into duplicated MM suggest that these tumors can behave aggressively despite their technically intramucosal location...
  62. ncbi request reprint The effect of the metabolic syndrome, hepatic steatosis and steatohepatitis on liver fibrosis in hereditary hemochromatosis
    Leon A Adams
    Department of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MI, USA
    Liver Int 26:298-304. 2006
    ..We sought to examine whether the metabolic syndrome, hepatic steatosis or steatohepatitis influenced hepatic fibrosis among patients with HH and iron overload...
  63. pmc Adult autoimmune enteropathy: Mayo Clinic Rochester experience
    Salma Akram
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 5:1282-90; quiz 1245. 2007
    ..Autoimmune enteropathy is a rare cause of intractable diarrhea associated with circulating gut autoantibodies and a predisposition to autoimmunity. It is rarely observed in adults, with only 11 cases reported to date...
  64. ncbi request reprint Liver transplantation for severe intrahepatic noncirrhotic portal hypertension
    Alyssa M Krasinskas
    Departments of Pathology, University of Pittsburgh, PA, USA
    Liver Transpl 11:627-34; discussion 610-1. 2005
    ..Importantly, however, a diagnosis of cirrhosis is not required in this group of patients to qualify them for OLT, and these patients have good long-term graft function after OLT...
  65. ncbi request reprint An assessment of chromosomal alterations detected by fluorescence in situ hybridization and p16 expression in sporadic and primary sclerosing cholangitis-associated cholangiocarcinomas
    Ryan D DeHaan
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Hum Pathol 38:491-9. 2007
    ..Polysomy and homozygous 9p21 deletion are common in both sporadic and PSC-associated CCAs and are frequently detectable in PSC-associated biliary dysplasia...
  66. ncbi request reprint Gastrointestinal plasmacytoma that caused anemia in a patient with multiple myeloma
    Tuba Esfandyari
    Mayo Clinic, Rochester, MN 55905, USA
    Nat Clin Pract Gastroenterol Hepatol 4:111-5. 2007
    ..He had required more than 15 U of packed red blood cells within a 2-month period for his anemia, despite recombinant erythropoietin treatment, and his hemoglobin level was persistently below 9 g/dl...
  67. ncbi request reprint Achlorhydria, parietal cell hyperplasia, and multiple gastric carcinoids: a new disorder
    Pedram Argani
    Am J Surg Pathol 31:488. 2007
  68. ncbi request reprint Distinguishing gastrointestinal stromal tumors from their mimics: an update
    Susan C Abraham
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Adv Anat Pathol 14:178-88. 2007
    ..It is important to separate GISTs from these potential mimics because their treatment and prognosis can differ markedly...
  69. ncbi request reprint Hemobilia caused by cytomegalovirus cholangiopathy
    Ganapathy A Prasad
    Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55901, USA
    Am J Gastroenterol 100:2592-5. 2005
    ..Biliary CMV disease is rare in HIV-negative persons, but should be considered in a patient with unexplained hemobilia. Cholangioscopy may be useful for diagnosis...
  70. ncbi request reprint Clinicopathologic findings and outcomes of liver transplantation using grafts from donors with unrecognized and unusual diseases
    Surakit Pungpapong
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA
    Liver Transpl 12:310-5. 2006
    ..In conclusion, long-term follow-up is necessary to confirm these findings and understand the impact of using these grafts...
  71. ncbi request reprint Multicenter experience with upper gastrointestinal polyps in pediatric patients with familial adenomatous polyposis
    Thomas M Attard
    Department of Pediatrics, The University of Nebraska Medical Center, Omaha, NE 68198 5160, USA
    Am J Gastroenterol 99:681-6. 2004
    ..There are few data describing pediatric upper gastrointestinal FAP resulting in conflicting screening recommendations...
  72. ncbi request reprint Chronic antral ulcer associated with gastroduodenal lymphocytic phlebitis
    Susan C Abraham
    Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 28:1659-63. 2004
    ..We hypothesize that there may be more cases of upper gastrointestinal ELP than are diagnosed as such, in part because the diagnosis can be made only on surgical resections specimens...
  73. ncbi request reprint Surgical and chemotherapy treatment outcomes of goblet cell carcinoid: a tertiary cancer center experience
    Tuan H Pham
    Department of Colorectal Surgery, Mayo Clinic, 200 First Street S W, Rochester, Minnesota 55905, USA
    Ann Surg Oncol 13:370-6. 2006
    ..Goblet cell carcinoid (GCC) is a rare malignant tumor with distinct histological and clinical features. Our goals were to review the surgical and chemotherapy outcomes of patients with GCC...
  74. ncbi request reprint Achlorhydria, parietal cell hyperplasia, and multiple gastric carcinoids: a new disorder
    Susan C Abraham
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 29:969-75. 2005
    ....