R R Turner

Summary

Affiliation: John Wayne Cancer Institute
Country: USA

Publications

  1. ncbi request reprint Newer pathologic assessment techniques for colorectal carcinoma
    Roderick R Turner
    Department of Pathology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, USA
    Clin Cancer Res 13:6871s-6s. 2007
  2. ncbi request reprint Histopathologic assessment of the sentinel lymph node in breast cancer
    R R Turner
    John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, California 90404, USA
    Ann Surg Oncol 8:56S-59S. 2001
  3. ncbi request reprint Colorectal carcinoma nodal staging. Frequency and nature of cytokeratin-positive cells in sentinel and nonsentinel lymph nodes
    Roderick R Turner
    Department of Pathology, Saint John s Health Center, Santa Monica, Calif, USA
    Arch Pathol Lab Med 127:673-9. 2003
  4. ncbi request reprint Prospective observational study of sentinel lymphadenectomy without further axillary dissection in patients with sentinel node-negative breast cancer
    A E Giuliano
    Joyce Eisenberg Keefer Breast Center, Division of Surgical Oncology, Statistical Coordinating Unit, Department of Nuclear Medicine, Santa Monica, CA, USA
    J Clin Oncol 18:2553-9. 2000
  5. ncbi request reprint Molecular staging of early colon cancer on the basis of sentinel node analysis: a multicenter phase II trial
    A J Bilchik
    Department of Molecular Oncology, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, CA 90404, USA
    J Clin Oncol 19:1128-36. 2001
  6. pmc Prognostic relevance of occult nodal micrometastases and circulating tumor cells in colorectal cancer in a prospective multicenter trial
    Kazuo Koyanagi
    Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, California 90404, USA
    Clin Cancer Res 14:7391-6. 2008
  7. pmc Assessment of DNA methylation status in early stages of breast cancer development
    A Q van Hoesel
    Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    Br J Cancer 108:2033-8. 2013
  8. pmc Aberrant hypermethylation in primary tumours and sentinel lymph node metastases in paediatric patients with cutaneous melanoma
    K T Huynh
    Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    Br J Dermatol 166:1319-26. 2012
  9. ncbi request reprint Pathologic examination of sentinel lymph node for breast carcinoma
    R R Turner
    Department of Surgery, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica California 90404, USA
    World J Surg 25:798-805. 2001
  10. ncbi request reprint Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial
    Anton J Bilchik
    Department of Gastrointestinal Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, and Michigan State University McLaren Regional Medical Center, Flint, MI, USA
    Ann Surg 246:568-75; discussion 575-7. 2007

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Newer pathologic assessment techniques for colorectal carcinoma
    Roderick R Turner
    Department of Pathology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, USA
    Clin Cancer Res 13:6871s-6s. 2007
    ..This brief review discusses the most promising of these approaches and evidence supporting their potential clinical utility...
  2. ncbi request reprint Histopathologic assessment of the sentinel lymph node in breast cancer
    R R Turner
    John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, California 90404, USA
    Ann Surg Oncol 8:56S-59S. 2001
    ..Pathologic characteristics of the primary tumor and SLN metastasis determine the risk of non-SLN metastasis in the same lymphatic basin...
  3. ncbi request reprint Colorectal carcinoma nodal staging. Frequency and nature of cytokeratin-positive cells in sentinel and nonsentinel lymph nodes
    Roderick R Turner
    Department of Pathology, Saint John s Health Center, Santa Monica, Calif, USA
    Arch Pathol Lab Med 127:673-9. 2003
    ..Nodal staging accuracy is important for prognosis and selection of patients for chemotherapy. Sentinel lymph node (SLN) mapping improves staging accuracy in breast cancer and melanoma and is being investigated for colorectal carcinoma...
  4. ncbi request reprint Prospective observational study of sentinel lymphadenectomy without further axillary dissection in patients with sentinel node-negative breast cancer
    A E Giuliano
    Joyce Eisenberg Keefer Breast Center, Division of Surgical Oncology, Statistical Coordinating Unit, Department of Nuclear Medicine, Santa Monica, CA, USA
    J Clin Oncol 18:2553-9. 2000
    ..Therefore, we hypothesized that SLND alone in patients with tumor-negative sentinel nodes would achieve axillary control, with minimal complications...
  5. ncbi request reprint Molecular staging of early colon cancer on the basis of sentinel node analysis: a multicenter phase II trial
    A J Bilchik
    Department of Molecular Oncology, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, CA 90404, USA
    J Clin Oncol 19:1128-36. 2001
    ..We hypothesized that multimarker reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of sentinel lymph nodes (SNs) draining a primary CRC could detect micrometastases not detected by conventional histopathologic analysis...
  6. pmc Prognostic relevance of occult nodal micrometastases and circulating tumor cells in colorectal cancer in a prospective multicenter trial
    Kazuo Koyanagi
    Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, California 90404, USA
    Clin Cancer Res 14:7391-6. 2008
    ..Nodal micrometastasis and circulating tumor cells detected by multimarker quantitative real-time reverse transcription-PCR (qRT-PCR) may have prognostic importance in patients with colorectal cancer...
  7. pmc Assessment of DNA methylation status in early stages of breast cancer development
    A Q van Hoesel
    Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    Br J Cancer 108:2033-8. 2013
    ..In this study, alterations in DNA methylation levels were monitored during benign, premalignant and malignant stages of ductal breast cancer development...
  8. pmc Aberrant hypermethylation in primary tumours and sentinel lymph node metastases in paediatric patients with cutaneous melanoma
    K T Huynh
    Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    Br J Dermatol 166:1319-26. 2012
    ..Yet, there are no molecular prognostic studies identifying these differences...
  9. ncbi request reprint Pathologic examination of sentinel lymph node for breast carcinoma
    R R Turner
    Department of Surgery, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica California 90404, USA
    World J Surg 25:798-805. 2001
    ..This review discusses our current understanding of the pathologic and molecular techniques for sentinel node examination...
  10. ncbi request reprint Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial
    Anton J Bilchik
    Department of Gastrointestinal Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, and Michigan State University McLaren Regional Medical Center, Flint, MI, USA
    Ann Surg 246:568-75; discussion 575-7. 2007
    ..6% rate of micrometastases (MM) identified by immunohistochemical staining (IHC) of H&E-negative SNs in CC. We hypothesized that these MM have prognostic importance...
  11. ncbi request reprint One hundred consecutive cases of sentinel lymph node mapping in early colorectal carcinoma: detection of missed micrometastases
    Thomas F Wood
    John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    J Gastrointest Surg 6:322-9; discussion 229-30. 2002
    ..Further studies are necessary to elucidate the clinical relevance of these micrometastases...
  12. doi request reprint Nodal stage classification for breast carcinoma: improving interobserver reproducibility through standardized histologic criteria and image-based training
    Roderick R Turner
    Department of Pathology, Saint John s Health Center, 1328 Twenty Second St, Santa Monica, CA 90404, USA
    J Clin Oncol 26:258-63. 2008
    ..We sought to determine whether a set of clearly defined histologic criteria could lead to reproducible nodal classification by pathologists...
  13. ncbi request reprint Lymphoscintigraphy and lymphatic mapping for identification of sentinel lymph nodes
    E C Hsueh
    Joyce Eisenberg Keefer Breast Center and the Division of Surgical Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, USA
    World J Surg 25:794-7. 2001
    ....
  14. pmc Human high molecular weight-melanoma-associated antigen: utility for detection of metastatic melanoma in sentinel lymph nodes
    Yasufumi Goto
    Department of Molecular Oncology, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA
    Clin Cancer Res 14:3401-7. 2008
    ..Immunohistochemical staining (IHC) using S-100p-HMB-45-, and MART-1-specific antibodies is used for detecting metastases in sentinel lymph nodes (SLN). However, improvement in IHC is needed for melanoma micrometastasis detection...
  15. ncbi request reprint Nonsentinel node metastases in breast cancer patients with isolated tumor cells in the sentinel node: implications for completion axillary node dissection
    Kristine E Calhoun
    The Joyce Eisenberg Keefer Breast Center, John Wayne Cancer Institute at Saint John s Health Center, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA
    Am J Surg 190:588-91. 2005
    ..We hypothesized that the number of positive non-SLNs is low and ALND is unnecessary for most patients with ITC...
  16. doi request reprint Impact of micrometastases in the sentinel node of patients with invasive breast cancer
    Nora M Hansen
    John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    J Clin Oncol 27:4679-84. 2009
    ..This study is based on the new sixth edition of the American Joint Committee on Cancer (AJCC) staging criteria...
  17. pmc Prognostic significance of molecular upstaging of paraffin-embedded sentinel lymph nodes in melanoma patients
    Hiroya Takeuchi
    Department of Molecular Oncology, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, CA 90404, USA
    J Clin Oncol 22:2671-80. 2004
    ....
  18. ncbi request reprint Peptide nucleic acid clamp PCR: a novel K-ras mutation detection assay for colorectal cancer micrometastases in lymph nodes
    Bret Taback
    Department of Molecular Oncology, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, CA 90404, USA
    Int J Cancer 111:409-14. 2004
    ..This study demonstrates the utility, specificity and sensitivity of PNA clamp PCR assay in identifying occult micrometastases in the SLN of CRC patients by single-base mutation analysis...
  19. ncbi request reprint Prospective multicenter trial of staging adequacy in colon cancer: preliminary results
    Anton J Bilchik
    John Wayne Cancer Institute and Saint Johns Health Center, Santa Monica, CA 90404, USA
    Arch Surg 141:527-33; discussion 533-4. 2006
    ..A 25% recurrence rate in patients with node-negative CRC suggests that current staging practices are inadequate. Focused analysis of the sentinel node (SN) by multiple sectioning and immunohistochemistry improves staging accuracy...
  20. ncbi request reprint Carbon dye histologically confirms the identity of sentinel lymph nodes in cutaneous melanoma
    P I Haigh
    Roy E. Coats Research Laboratories, Division of Surgical Oncology, John Wayne Cancer Institute at Saint John's Health Center, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA
    Cancer 92:535-41. 2001
    ..The location of carbon particles within SNs may assist the pathologist in the detection of metastases, thereby decreasing the histopathologic false-negative rate of LM/SL and subsequently reducing the same-basin recurrence rate...
  21. doi request reprint Predictors of occult nodal metastasis in colon cancer: results from a prospective multicenter trial
    Nabil Wasif
    John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA, USA
    Surgery 147:352-7. 2010
    ..We sought to investigate the correlation of clinicopathologic features of colon cancer with OMs and to identify predictors of OM...
  22. ncbi request reprint Effect of lymphatic mapping on the new tumor-node-metastasis classification for colorectal cancer
    Anton J Bilchik
    Division of Surgical Oncology, John Wayne Cancer Institute at Saint John s Health Center, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA
    J Clin Oncol 21:668-72. 2003
    ..This study examined the role of lymphatic mapping (LM) in the application of the new tumor-node-metastasis (TNM) classification for MM and ITC...
  23. ncbi request reprint Molecular diagnosis of micrometastasis in the sentinel lymph node
    Hiroya Takeuchi
    Department of Molecular Oncology, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, California 90404, USA
    Cancer Treat Res 127:221-52. 2005
  24. pmc Lymphatic mapping establishes the role of BRAF gene mutation in papillary thyroid carcinoma
    Joseph Kim
    Department of Molecular Oncology, John Wayne Cancer Institute at Saint Johns Hospital, Santa Monica, CA 90404, USA
    Ann Surg 244:799-804. 2006
    ..To define the role of BRAF gene mutation in the progression of papillary thyroid carcinoma...
  25. pmc Lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: therapeutic utility and implications of nodal microanatomy and molecular staging for improving the accuracy of detection of nodal micrometastases
    Donald L Morton
    Roy E Coats Research Laboratories of the John Wayne Cancer Insstitute at Saint John s Health Center, Santa Monica, CA 90404, USA
    Ann Surg 238:538-49; discussion 549-50. 2003
    ....
  26. ncbi request reprint Isolated tumor cells in the sentinel node affect long-term prognosis of patients with melanoma
    Randall P Scheri
    Department of Surgical Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA, USA
    Ann Surg Oncol 14:2861-6. 2007
    ..The clinical significance of isolated tumor cells (ITCs) in the melanoma-draining sentinel nodes (SNs) is unclear...
  27. ncbi request reprint Proteomic profiling of primary breast cancer predicts axillary lymph node metastasis
    Taku Nakagawa
    Department of Molecular Oncology, Division of Biostatistics, and Joyce Eisenberg Keefer Breast Center, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
    Cancer Res 66:11825-30. 2006
    ..016 and 0.0083, respectively). ProteinChip array analysis identified differential protein peaks in primary breast cancers that predict the presence and number of ALN metastases and non-SLN status...
  28. pmc Chemokine receptor CXCR4 expression in patients with melanoma and colorectal cancer liver metastases and the association with disease outcome
    Joseph Kim
    Department of Molecular Oncology, Gastrointestinal Cancer Section, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, CA 90404, USA
    Ann Surg 244:113-20. 2006
    ..To determine the role of chemokine receptor (CR) expression in patients with melanoma and colorectal cancer (CRC) liver metastases...
  29. doi request reprint Quantitative analysis of methylation of genomic loci in early-stage rectal cancer predicts distant recurrence
    Michiel F G de Maat
    Department of Molecular Oncology, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA
    J Clin Oncol 26:2327-35. 2008
    ..We then explored in a different clinical patient group whether these epigenetic changes could be correlated with clinical outcome...
  30. ncbi request reprint Melanoma recurrence patterns after negative sentinel lymphadenectomy
    Theresa G Zogakis
    Roy E Coats Research Laboratories, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, CA 90404, USA
    Arch Surg 140:865-71; discussion 871-2. 2005
    ..A tumor-negative sentinel node (SN) does not eliminate the chance of melanoma recurrence. Patterns of metastasis can be identified and characterized in patients with tumor-negative SNs...
  31. ncbi request reprint Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival
    Joseph Kim
    Department of Molecular Oncology, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA
    J Clin Oncol 23:2744-53. 2005
    ..Our hypothesis was that the chemokine receptor CXCR4 expressed by CRC is a prognostic factor for poor disease outcome...
  32. pmc Importance of sentinel lymph node biopsy in patients with thin melanoma
    Byron E Wright
    Department of Surgical Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, California 90404, USA
    Arch Surg 143:892-9; discussion 899-900. 2008
    ..The status of the sentinel node (SN) confers important prognostic information for patients with thin melanoma...
  33. ncbi request reprint Assessment of methylation events during colorectal tumor progression by absolute quantitative analysis of methylated alleles
    Michiel F G de Maat
    Department of Molecular Oncology, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA
    Mol Cancer Res 5:461-71. 2007
    ....
  34. ncbi request reprint American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer
    Gary H Lyman
    University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    J Clin Oncol 23:7703-20. 2005
    ..To develop a guideline for the use of sentinel node biopsy (SNB) in early stage breast cancer...
  35. ncbi request reprint Outcomes for women with ductal carcinoma-in-situ and a positive sentinel node: a multi-institutional audit
    Katrina H Moore
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, MRI 1026, New York, NY 10021, USA
    Ann Surg Oncol 14:2911-7. 2007
    ..Although it is well established that nodal status for invasive disease is prognostically important, the clinical relevance of a positive SLN in patients with DCIS remains undetermined...